From current issue: 5 (95)
ReviewMetastatic Melanoma A Review of Current and Future Treatment OptionsEmanual Maverakis, Lynn A. Cornelius, Glen M. Bowen, Tiffany Phan, Falin B. Patel, Sarah Fitzmaurice, Young He, Barbara Burrall, Christopher Duong, April M. Kloxin, Hawa Sultani, Reason Wilken, Steve R. Martinez, Forum Patel
Despite advances in treatment and surveillance, melanoma continues to claim approximately 9,000 lives in the US annually (SEER 2013). The National Comprehensive Cancer Network currently recommends ipilumumab, vemurafenib, dabrafenib, and high-dose IL-2 as first line agents for Stage IV melanoma. Little data exists to guide management of cutaneous and subcutaneous metastases despite the fact that t ...
Clinical ReportClinical Spectrum of Skin Manifestations of Lyme Borreliosis in 204 Children in AustriaMartin Glatz, Astrid Resinger, Kristina Semmelweis, Christina M. Ambros-Rudolph, Robert R. Müllegger
The spectrum of skin manifestations of Lyme borreliosis in children is not well characterized. We conducted a retrospective study to analyze the clinical characteristics, seroreactivity to Borrelia burgdorferi sensu lato, and outcome after treatment in 204 children with skin manifestations of Lyme borreliosis seen in 19962011. Solitary erythema migrans was the most common manifestation (44.6%), ...
Clinical ReportCyclosporine Treatment in Severe Gestational PemphigoidLaura Huilaja, Kaarin Mäkikallio, Katariina Hannula-Jouppi, Liisa Väkevä, Johanna Höök-Nikanne, Kaisa Tasanen
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Gestational pemphigoid, a rare autoimmune skin disease typically occurring during pregnancy, is caused by autoantibodies against collagen XVII. Clinically it is characterised by severe itching followed by erythematous and bullous lesions of the skin. Topical or oral glucocorticoids usually relieve symptoms, but in more severe cases systemic immunosuppressive treatments are needed. Data on immunosu ...
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In This Issue - 2015-05-25
IFN-γ in vitiligo, is it the fuel or the fire?
John E. Harris
Special Report - 2015-05-22
Efficacy of Rituximab for Pemphigus: A Systematic Review and Meta-analysis of Different Regimens
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Pathogenesis of Multiple Lentigines in LEOPARD Syndrome with PTPN11 Gene Mutation
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Serum Creatinine Levels During and After Long-term Treatment with Cyclosporine A in Patients with Severe Atopic Dermatitis
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