Content - Volume 97, Issue 1
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Editor's choice in this issue
EDITORIAL
Anders Vahlquist, Artur Schmidtchen, Agneta Andersson
Abstract is missing (Editorial)
Page: 3
INVESTIGATIVE REPORT
Vivien Marasigan, Marie-Anne Morren, Julien Lambert, Karen Medaer, Steffen Fieuws, Tamar Nijsten, Marjan Garmyn
Heightened cutaneous immune surveillance in atopic patients may inhibit development of melanoma. The aim of this study was to analyse the association between atopy and melanoma (development and outcome). A total of 188 cases of melanoma and 596 healthy controls were interviewed by telephone with a standardized questionnaire on atopic, demographic and melanoma characteristics. Cases were matched wi ...
Pages: 54-57
SHORT COMMUNICATION
Peter Kirchmeier, Andreas Zimmer, Bakar Bouadjar, Bernd Rösler, Judith Fischer
Abstract is missing (Short communication)
Pages: 102-104
All articles
EDITORIAL
Anders Vahlquist, Artur Schmidtchen, Agneta Andersson
Abstract is missing (Editorial)
Page: 3
SPECIAL REPORT
Laurent Misery, Sonja Ständer, Jacek C. Szepietowski, Adam Reich, Joanna Wallengren, Andrea W.M. Evers, Kenji Takamori, Emilie Brenaut, Christelle Le Gall-Ianotto, Joachim Fluhr, Enzo Berardesca, Elke Weisshaar
Sensitive skin is a frequent complaint in the general population, in patients, and among subjects suffering from itch. The International Forum for the Study of Itch (IFSI) decided to initiate a special interest group (SIG) on sensitive skin. Using the Delphi method, sensitive skin was defined as “A syndrome defined by the occurrence of unpleasant sensations (stinging, burning, pain, pruritus, an ...
Pages: 4-6
SPECIAL REPORT
Friederike Fiedler, Gabriele I. Stangl, Eckhard Fiedler, Klaus-Michael Taube
Few well-defined, evidence-based nutritional recommendations for people with skin diseases have been published in the scientific literature and standard dermatological textbooks. Using a systematic review of acne vulgaris as an example, the aim of this study was to determine whether there are systematic studies on the topic and, if so, of what quality. Four evidence levels were defined: (A) double ...
Pages: 7-9
INVESTIGATIVE REPORT
Adam Taylor, David C. Budd, Barbara Shih, Oliver Seifert, Andrew Beaton, Tracey Wright, Maria Dempsey, Fiona Kelly, Julia Egerton, Richard P. Marshall, Nicola Aston, Ardeshir Bayat
The keloid lesion is recognised as a spatially heterogeneous mass both in cellular and acellular composition and biological activity. Here, we have utilised a bioinformatic approach to determine whether this spatial heterogeneity is also evident at the molecular level and to identify key upstream regulators of signalling pathways enriched in the lesion in a spatially-restricted manner. Differentia ...
Pages: 10-16
INVESTIGATIVE REPORT
Alina Jankowska-Konsur, Christopher Kobierzycki, Adam Reich, Aleksandra Piotrowska, Agnieszka Gomulkiewicz, Mateusz Olbromski, Marzena Podhorska-Okołów, Piotr Dzięgiel, Jacek C. Szepietowski
SOX18 is a transcription factor involved in the development of hair follicle, blood and lymphatic vessels, as well as regenerative processes. In addition, accumulated data indicate the role of SOX18 in tumourigenesis. So far, no studies on the role of SOX18 expression in mycosis fungoides (MF), the most common primary cutaneous T-cell lymphoma, have been performed. Therefore, we evaluated SOX18 ex ...
Pages: 17-23
INVESTIGATIVE REPORT
Asri Wijayanti, Cathy Y. Zhao, David Boettiger, Yi Z. Chiang, Norito Ishii, Takashi Hashimoto, Dedee F. Murrell
A significant obstacle in guiding evidence-based management of bullous pemphigoid (BP) is the lack of a standardised, validated scoring system for the condition. The aim of this study is to evaluate the suitability of the Bullous Pemphigoid Disease Area Index (BPDAI) and the Autoimmune Bullous Skin disorder Intensity Score (ABSIS) as outcome measures for BP in clinical trials. Thirty-two BP patien ...
Pages: 24-31
INVESTIGATIVE REPORT
Carina Grönhagen, Karin Nilzén, Oliver Seifert, Kristofer Thorslund
Bullous pemphigoid (BP) is the most common autoimmune blistering disease. Since 2001, data from all specialized outpatient and inpatient care institutions in Sweden, have been registered with the National Patient Register (NPR), based on a unique personal identification number. Previous validations of the register have shown high accuracy for various non-dermatological autoimmune diseases. In orde ...
Pages: 32-35
INVESTIGATIVE REPORT
Magdalena Trzeciak, Monika Sakowicz-Burkiewicz, Martyna Wesserling, Daria Dobaczewska, Jolanta Gleń, Roman Nowicki, Tadeusz Pawelczyk
Changes in the expression of cornified envelope (CE) proteins are thought to affect the development and course of atopic dermatitis (AD). The aim of this study was to examine the expression level of CE proteins in order to identify new molecular markers of the AD phenotype. Expression levels of CE proteins were evaluated in the skin of patients with AD (38 biopsies) and healthy subjects (26 biopsi ...
Pages: 36-41
INVESTIGATIVE REPORT
Uwe Gieler, Stefanie Schoof, Tanja Gieler, Sibylle Scheewe, Christina Schut, Jörg Kupfer
This study investigated the extent to which single mothers of children with atopic eczema experience disease-related stress. A total of 96 mothers were divided into 4 groups: mothers living with a partner, who had or did not have a child with atopic eczema, and single mothers, who had or did not have a child with atopic eczema. The following questionnaires were used to assess psychological burden: ...
Pages: 42-46
INVESTIGATIVE REPORT
Magdalena Lange, Jolanta Gleń, Monika Zabłotna, Bogusław Nedoszytko, Małgorzata Sokołowska-Wojdyło, Krzysztof Rębała, Hanna Ługowska-Umer, Marek Niedoszytko, Aleksandra Górska, Monika Sikorska, Agata Zawadzka, Roman Nowicki
Data on interleukin-31 (IL-31) involvement in the patho-genesis of mastocytosis, and its impact on pruritus development in the disease, are limited. The aim of this study was to analyse distinct IL-31 gene polymorphisms in 127 patients (age 0.5–76 years) with mastocytosis and their correlation with clinical presentation, pruritus and serum IL-31 levels. In patients with mastocytosis, the frequen ...
Pages: 47-53
INVESTIGATIVE REPORT
Vivien Marasigan, Marie-Anne Morren, Julien Lambert, Karen Medaer, Steffen Fieuws, Tamar Nijsten, Marjan Garmyn
Heightened cutaneous immune surveillance in atopic patients may inhibit development of melanoma. The aim of this study was to analyse the association between atopy and melanoma (development and outcome). A total of 188 cases of melanoma and 596 healthy controls were interviewed by telephone with a standardized questionnaire on atopic, demographic and melanoma characteristics. Cases were matched wi ...
Pages: 54-57
CLINICAL REPORT
Camilla Pasternack, Katri Kaukinen, Kalle Kurppa, Markku Mäki, Pekka Collin, Kaisa Hervonen, Timo Reunala, Heini Huhtala, Leila Kekkonen, Teea Salmi
Dermatitis herpetiformis (DH) is an extraintestinal manifestation of coeliac disease. The burden of illness in untreated coeliac disease is known to be considerable, but corresponding evidence for DH is lacking. In this study the burden of DH was evaluated prospectively in 52 patients newly diagnosed with DH using a study questionnaire and a validated Psychological General Well-Being (PGWB) questi ...
Pages: 58-62
CLINICAL REPORT
Hjalte H. Andersen, Camilla Melholt, Sigurd D. Hilborg, Anne Jerwiarz, Amalie Randers, Amalie Simoni, Jesper Elberling, Lars Arendt-Nielsen
A frequent empirical observation is that cold-induced counter-irritation may attenuate itch. The aim of this randomized, single-blinded, exploratory study was to evaluate the counter-irritation effects of cold-stimulation and topical application of transient receptor potential TRPA1/M8-agonists (trans-cinnamaldehyde/L-menthol, respectively), on histamine-induced itch, wheals and neurogenic inflamm ...
Pages: 63-70
CLINICAL REPORT
Sabine Steinke, Mandy Gutknecht, Claudia Zeidler, Anette Maria Dieckhöfer, Olga Herrlein, Hannah Lüling, Sonja Ständer, Matthias Augustin
In brachioradial pruritus and notalgia paraesthetica, the 8% capsaicin patch is a novel and effective, but cost-intense, therapy. Routine data for 44 patients were collected 6 months retrospectively and prospectively to first patch application. The cost to health insurance and the patient, and patient-reported outcomes were analysed (visual analogue scale, numerical rating scale, verbal rating sca ...
Pages: 71-76
CLINICAL REPORT
Ji Hyun Lee, Han Mi Jung, Kyung Do Han, Seung-Hwan Lee, Jun Young Lee, Yong Gyu Park, Young Min Park
Whether metabolic syndrome (MetS) and its components are risk factors for atopic dermatitis (AD) remains unclear. This study investigated the association between MetS and AD in Korean adults. Nationally representative data for 5,007 Korean adults, aged 19–40 years, from the cross-sectional Korea National Health and Nutrition Examination Survey 2010–2011 were analysed. AD in female patients was ...
Pages: 77-80
CLINICAL REPORT
Antonietta Cappuccio, Tommaso Limonta, Aurora Parodi, Antonio Cristaudo, Filomena Bugliaro, Serafinella P. Cannavò, Oliviero Rossi, Carlotta Gurioli, Alice Vignoli, Roberta Parente, Enrico Iemoli, Giacomo Caldarola, Ornella De Pità, Sergio Di Nuzzo, Mauro Cancian, Concetta Potenza, Marco Caminati, Luca Stingeni, Rosita Saraceno, Sara Trevisini, Angelo Piccirillo, Claudio Sciarrone, Rosanna Panebianco, Massimo Gola, Antonio Costanzo, Teresa Grieco, Katia Massaroni, Luigi Reale, Maria G. Marini
Chronic spontaneous urticaria (CSU) is perceived as a difficult to manage disease with negative impact on quality of life. The aim of this study was to highlight how to improve the care of people with CSU, using the methodology of narrative medicine. From June 2014 to March 2015, CSU-diagnosed patients and their physicians were asked to record their experiences of the condition in writing. Fourtee ...
Pages: 81-85
CLINICAL REPORT
Laura B. von Kobyletzki, Kim S. Thomas, Jochen Schmitt, Joanne R. Chalmers, Stefanie Deckert, Valeria Aoki, Elke Weisshaar, Jumoke Ahubelem Ojo, Åke Svensson
This study investigated the perspective of international patients on individual symptoms of atopic dermatitis (eczema) in determining treatment response. A questionnaire was developed to evaluate the importance of symptoms from the patient’s perspective. Patients were asked: “How important are these features in deciding whether or not a treatment is working?”, and rated symptoms on a 5-point ...
Pages: 86-90
CLINICAL REPORT
Ewa Wojtyna, Patryk Łakuta, Kamil Marcinkiewicz, Beata Bergler-Czop, Ligia Brzezińska-Wcisło
The aim of this study was to examine the importance of psychosocial factors, such as emotional and instrumental social support, distress, and assumptions about appearance and its salience to one’s self-worth, and to relate these factors to depressive symptoms in patients with psoriasis, according to gender. A group of 219 patients with psoriasis, aged 18–70 years completed the Beck Depression ...
Pages: 91-97
CLINICAL REPORT
Reena Shah, Ruth E. Taylor, Anthony Bewley
Delusional infestation (DI) is an uncommon psychiatric disorder in which patients present with the false and fixed belief (i.e. a delusion) that their skin and/or their environment is infested despite objective evidence to the contrary. Within psychodermatology specialist clinics there is a high rate of DI referrals. What is not known is the level of psychiatric and psychological co-morbidities as ...
Pages: 98-101
SHORT COMMUNICATION
Peter Kirchmeier, Andreas Zimmer, Bakar Bouadjar, Bernd Rösler, Judith Fischer
Abstract is missing (Short communication)
Pages: 102-104
SHORT COMMUNICATION
Katarzyna B. Gostyńska, Jeroen Bremer, Krista K. van Dijk-Bos, Richard Sinke, Anna Maria G. Pasmooij, Marcel F. Jonkman
Abstract is missing (Short communication)
Pages: 105-107
SHORT COMMUNICATION
Leila Youssefian, Hassan Vahidnezhad, Yahya Aghighi, Vahid Ziaee, Sirous Zeinali, Maryam Abiri, Jouni Uitto
Abstract is missing (Short communication)
Pages: 108-109
SHORT COMMUNICATION
Hiram de Almeida Jr, Cristina Has, Greice Rampon, Henrique Isaacsson, Luis Antonio Suita de Castro
Abstract is missing (Short communication)
Pages: 110-111
SHORT COMMUNICATION
Satoshi Nakahara, Satoshi Fukushima, Junji Yamashita, Yosuke Kubo, Aki Tokuzumi, Azusa Miyashita, Miho Harada, Kayo Nakamura, Masatoshi Jinnin, Hironobu Ihn
Abstract is missing (Short communication)
Pages: 112-114
SHORT COMMUNICATION
Miri Kim, Young Hoon Yoon, Ji Hyun Lee, Dong Wook Kim, Hyun Jeong Park
Abstract is missing (Short communication)
Pages: 115-116
SHORT COMMUNICATION
Marta Urech, Athanassios Kyrgidis, Giuseppe Argenziano, Camilla Reggiani, Elvira Moscarella, Caterina Longo, Roberto Alfano, Iris Zalaudek, Aimilios Lallas
Abstract is missing (Short communication)
Pages: 117-119
SHORT COMMUNICATION
Noora Neittaanmäki-Perttu, Toni Tapani Karppinen, Taneli Tani, Erna Snellman, Mari Grönroos
Abstract is missing (Short communication)
Pages: 120-121
SHORT COMMUNICATION
Yumeng Qi, Li Qiu, Song Zheng, Songbai LI, Ting Xiao
Abstract is missing (Short communication)
Pages: 122-123
SHORT COMMUNICATION
Sam Polesie, Anette Gente Lidholm
Abstract is missing (Short communication)
Pages: 124-125
SHORT COMMUNICATION
Kristian B. Arvesen, Troels Herlin, Dorthe A. Larsen, Uffe Koppelhus, Mette Ramsing, Anne-Bine Skytte, Mette Sommerlund
Abstract is missing (Short communication)
Pages: 126-127
SHORT COMMUNICATION
Christian D. Sadik, Hendri H. Pas, Michael K. Bohlmann, Sadegh Mousavi, Sandrine Benoit, Miklós Sárdy, Jorrit B. Terra, Ana L. Lima, Christoph M. Hammers, Nina van Beek, Christine Bangert, Detlef Zillikens, Enno Schmidt
Abstract is missing (Short communication)
Pages: 128-130
SHORT COMMUNICATION
Lisa Groening, Livia Dunér Holthuis, Sam Polesie, Henrik H. Sönnergren
Abstract is missing (Short communication)
Pages: 131-132
SHORT COMMUNICATION
Jin-Wook Jeong, Michihiro Kono, Yoshie Hasegawa-Murakami, Toru Motoi, Kenji Yokota, Takaaki Matsumoto, Kaori Kaibuchi-Ando, Yoichi Kato, Toyohiro Tada, Masashi Akiyama
Abstract is missing (Short communication)
Pages: 133-134
SHORT COMMUNICATION
Anastasiya A. Chokoeva, Georgi K. Maximov, Uwe Wollina, James W. Patterson, Georgi Tchernev
Abstract is missing (Short communication)
Pages: 135-136
SHORT COMMUNICATION
Soo Hyeon Bae, Sook Jung Yun, Jee-Bum Lee, Seong-Jin Kim, Seung-Chul Lee, Young Ho Won
Abstract is missing (Short communication)
Pages: 137-138
SHORT COMMUNICATION
Sanna S. Wingfield Digby, Marianne Hald, Maiken C. Arendrup, Sofie V. Hjort, Kristian Kofoed
Abstract is missing (Short communication)
Pages: 139-140
SHORT COMMUNICATION
Takeshi Kato, Noriki Fujimoto, Shinichiro Honda, Norikazu Fujii, Masae Shirai, Takeshi Nakanishi, Gen Nakanishi, Toshihiro Tanaka
Abstract is missing (Short communication)
Pages: 141-142
QUIZ
Anaisa A.V. de Souza, Marcello M.S. Nico
Abstract is missing (Quiz)
Pages: 143-144
LETTER TO THE EDITOR
Elisabet Nylander, Petra Tunbäck
Abstract is missing (Correspondence)
Pages: 145-146
