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Preview of fully accepted papers, still not published in any volume

CLINICAL REPORT
Adult Patients with Atopic Eczema have a High Burden of Psychiatric Disease: A Finnish Nationwide Registry Study
Saana Kauppi, Jari Jokelainen, Markku Timonen, Kaisa Tasanen, Laura Huilaja
Atopic dermatitis is associated with several comorbidities. Epidemiological studies on psychiatric comorbidities in adult atopic dermatitis patients are sparse. We analyzed psychiatric comorbidities in a Finnish nationwide adult atopic dermatitis cohort. The study included 57,690 adult patients with atopic dermatitis as cases and 40,363 individuals diagnosed with melanocytic naevi as controls. Dat ...
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SHORT COMMUNICATION
Morbihan Syndrome Successfully Treated with Omalizumab
Pegah Kafi, Inger Edén, Carl Swartling
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder Resembling B-cell Pseudo­lymphoma on the Lip and Conjunctivae
Fumi Miyagawa, Yuki Aoki, Aya Hayashino, Chie Sotozono, Hideo Asada
Abstract is missing (Short communication)
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SPECIAL REPORT
European S2k Guideline on Chronic Pruritus
Elke Weisshaar, Jacek C. Szepietowski, Florence J. Dalgard, Simone Garcovich, Uwe Gieler, Ana M. Giménez-Arnau, Julien Lambert, Tabi Leslie, Thomas Mettang, Laurent Misery, Ekin Şavk, Markus Streit, Erwin Tschachler, Erwin Tschachler, Joanna Wallengren, Sonja Ständer
Pruritus is a frequent symptom in medicine. Population-based studies show that every 5th person in the general population has suffered from chronic pruritus at least once in the lifetime with a 12-month incidence of 7%. In patient populations its frequency is much higher depending on the underlying cause, ranging from around 25% in haemodialysis patients to 100% in skin diseases such as urticaria ...
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QUIZ
Stable Firm Pink Papules on a Woman in her 60s: A Quiz
Catherine Baker, Katherine R. Lee, Anh Khoa Pham, Robert E. LeBlanc, Joi B. Carter
Abstract is missing (Quiz)
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INVESTIGATIVE REPORT
Gliptin-associated Bullous Pemphigoid and the Expression of Dipeptidyl Peptidase-4/CD26 in Bullous Pemphigoid
Outi Lindgren, Outi Varpuluoma, Jussi Tuusa, Jorma Ilonen, Laura Huilaja, Nina Kokkonen, Kaisa Tasanen
Dipeptidyl peptidase-4 inhibitors (DPP-4i or gliptins) increase the risk of developing bullous pemphigoid (BP). To clarify, whether gliptin-associated BP has special features, we analyzed the clinical, histopathological and immunological features of 27 BP patients, 10 of which previously used gliptin medication. Compared to those who had not previously received gliptins, subjects who had, showed h ...
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SHORT COMMUNICATION
Progressive Nodular Histiocytosis with Large Nodules and a Bulky Mass
Takahiro Kiyohara, Kaoru Makimura, Mari Miyamoto, Takako Shijimaya, Naoko Nagano, Sei Nakamaru, Hirotsugu Tanimura
Abstract is missing (Short Communication)
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REVIEW
Nail Psoriasis: An Updated Review and Expert Opinion on Available Treatments, Including Biologics
Federico Bardazzi, Michela Starace, Francesca Bruni, Michela Magnano, Bianca Maria Piraccini, Aurora Alessandrini
Nail psoriasis affects 50–79% of patients with skin psoriasis and up to 80% of patients with psoriatic arthritis, and can also represent a negative prognostic factor in individuals with plaque psoriasis. Treatments for nail psoriasis are limited, as nails are often difficult to treat with topical therapies alone, and relapse is common. Among different systemic agents, secukinumab, a fully human ...
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SHORT COMMUNICATION
Economic Analysis of Herpes Zoster in a Hospital Setting in Hong Kong
Wai-kit Ming, Wing-yin Yu, Owen Tak-yin Tsang, Paul Kay-sheung Chan, Joyce Hoi-sze You
Abstract is missing (Short communication)
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CLINICAL REPORT
Low- vs. Middle-dose Total Skin Electron Beam Therapy for Mycosis Fungoides: An Efficiency-based Retrospective Survey of Skin Response
Annelies Taverniers, Aurélie Du-Thanh, Marie Charissoux, Christine Kerr, Olivier Dereure
Optimal doses of total skin electron beam therapy for mycosis fungoides remain to be established. Clinical efficiency and adverse effects of middle-dose (25 Gy) vs. low-dose (10–12 Gy) total skin electron beam therapy were retrospectively compared in a series of 14 and 12 mycosis fungoides, respectively. Overall skin response rate was 96.2% (92.9% middle-dose and 100% low-dose; not significant ( ...
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SHORT COMMUNICATION
Therapeutic Effectiveness of Immunoradiotherapy on Brain-metastatic BRAF/MEK Inhibitor-resistant Melanoma with Balloon Cell Change
Haruka Goto, Takatoshi Shimauchi, Kensuke Fukuchi, Naoki Yokota, Shinichiro Koizumi, Masahiro Aoshima, Yuno Endo, Yurika Masuda, Hidehiko Miyazawa, Akira Kasuya, Katsumasa Nakamura, Taisuke Ito, Yoshiki Tokura
Abstract is missing (Short communication)
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CLINICAL REPORT
Emotional Ability and Skin-restricted Lupus Evolution: A Longitudinal Study
Isabelle Jalenques, Fabien Rondepierre, Aurélien Mulliez, Michel D'Incan, Silla M. Consoli and The LuPsy cohort investigators
Impaired emotional abilities (higher scores of alexithymia and lower levels of emotional awareness) were found in patients with skin-restricted lupus, warranting examination of the relationship between these abilities and the evolution of skin-restricted lupus, using longitudinal data. A total of 75 consecutive outpatients with skin-restricted lupus were recruited and assessed by a dermatologist a ...
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SHORT COMMUNICATION
Nevus Count Associations with Thinner Nodular or Superficial Spreading Melanoma
Clio Dessinioti, Alan C. Geller, Arabella Stergiopoulou, Susan M. Swetter, Eszter Baltás, Jonathan E. Mayer, Timothy M. Johnson, Alexander J. Stratigos
Abstract is missing (Short communication)
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QUIZ
Vascular Mass of the Scalp in a Newborn: A Quiz
Afi-Emiliène Edee, Matthias Tallegas, Anne Jourdain, Antoine Listrat, Baptiste Morel, Annabel Maruani
Abstract is missing (Quiz)
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REVIEW
Drug-induced Linear IgA Bullous Dermatosis: a Case Report and Review of the Literature
Judith Lammer, Rüdiger Hein, Sophie Roenneberg, Tilo Biedermann, Thomas Volz
Linear IgA bullous dermatosis (LABD) is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. Although most reported cases are idiopathic, there is a subset of patients with drug-induced LABD. Various drugs have been associated with the drug-induced form of the disease. This paper reviews the literature on drugs reported to el ...
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QUIZ
Ulcers and Scars on the Trunk of a 20-month-old Boy: A Quiz
Tal Goldberger, Alexander Maly, Tamar Harel, Vered Molho-Pessach
Abstract is missing (Quiz)
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INVESTIGATIVE REPORT
Inhibiting Sphingosine Kinase 2 Derived-sphingosine-1-phosphate Ameliorates Psoriasis-like Skin Disease via Blocking Th17 Differentiation of Naïve CD4 T Lymphocytes in Mice
Sun-Hye Shin, Kyung-Ah Cho, Soojung Hahn, Younghay Lee, Yu-He Kim, So-Youn Woo, Kyung-Ha Ryu, Woo-Jae Park, Joo-Won Park
Sphingosine-1-phosphate (S1P) is a signalling sphingolipid metabolite that regulates important cell processes, including cell proliferation and apoptosis. Circulating S1P levels have been reported to be increased in patients with psoriasis relative to healthy patients. The aim of this study was to examine the potency of S1P inhibition using an imiquimod-induced psoriasis mouse model. Both topical ...
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CLINICAL REPORT
Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma
Juliette Hardy, Franck Boralevi, Stéphanie Mallet, Natalia Cabrera, Alexandre Belot, Alice Phan, Sébastien Barbarot, Audrey Duriez-Lasek, Christine Chiaverini, Thomas Hubiche, Emmanuel Mahé, Edouard Bégon, Emmanuelle Bourrat, Olivia Boccara, Hélène Aubert, Martine Grall Lerosey, Catherine Droitcourt, Maryam Piram, Juliette Mazereeuw-Hautier, and Research Group of the French Society of Paediatric Dermatology (SDFP in French)
Methotrexate has demonstrated its efficiency for the treatment of juvenile localized scleroderma but some patients may be resistant. The aim of our study was to define the profile of such patients. We performed an observational retrospective multicenter study between 2007 and 2016 and included all children seen in the French Paediatric Dermatology and Rheumatology departments with active localized ...
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SHORT COMMUNICATION
Agreement Between Self-reported and Dermatologists’ Diagnosis for Alopecia Areata and Atopic Dermatitis: A Bi-centric Prospective Study
Marie-Aleth Richard, Khaled Ezzedine
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons
Sarah Ehling, Tomoki Fukuyama, Mei-Chuan Ko, Thierry Olivry, Wolfgang Bäumer
Neuromedin B is expressed in nociceptive and itch-sensitive dorsal root ganglia neurons, but its peripheral pruritogenic potential is not well described. The potential of neuromedin B as a pruritogen and pro-inflammatory peptide in the skin was tested in vivo in an acute model in mice and monkeys as well as an allergic dermatitis model in mice. To identify the underlying mechanisms in vitro real t ...
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QUIZ
Erythematous Rash in a Transgender Patient: A Quiz
Francisco Galeano-Valle, Jeehea Sonya Haw
Abstract is missing (Quiz)
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CLINICAL REPORT
Strong Associations Between Inflammation, Pruritus and Mental Health in Dialysis Patients
Severin Schricker, Thorsten Heider, Moritz Schanz, Jürgen Dippon, Mark Dominik Alscher, Heinz Weiss, Thomas Mettang, Martin Kimmel
Pruritus, impaired mental health and inflammation contribute to morbidity in end-stage renal disease. There are no studies on all 3 conditions. We therefore obtained inflammatory parameter data (C-reactive protein and interleukin-6), pruritus data and psychological test data (36-Item Short-Form Health Survey, “Allgemeine Depressionsskala” and Toronto Alexithymia Scale-20) for 19 dialysis patie ...
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INVESTIGATIVE REPORT
Serum miR-125a-5p and CCL17 Upregulated in Chronic Spontaneous Urticaria and Correlated with Treatment Response
Liming Zhang, Ruiqun Qi, Yang Yang, Xinghua Gao, Hongdou Chen, Ting Xiao
Chronic spontaneous urticaria (CSU) is a common skin disorder associated with autoimmunity. MicroRNAs (miRNAs) are endogenous noncoding RNA molecules reported to be potential biomarkers for some autoimmune diseases. In this study, we investigated the association of miRNAs with CSU. A quantitative PCR (qPCR)-based array was generated from sera as obtained from 20 active CSU patients and 20 healthy ...
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INVESTIGATIVE REPORT
Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis
Weilong Zhong, Xia Wu, Wei Zhang, Jie Zhang, Xiaofan Chen, Shihong Chen, Haiyan Huang, Yong Yang, Bo Yu, Xia Dou
Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in chronic itch and inflammation. This study investigated the mRNA levels and immunoreactivity of the nerve growth factor, IL-31, thymic stromal lymphopoi ...
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CLINICAL REPORT
High Prevalence of Human Papillomavirus on Anal and Oral Samples from Men and Women with External Anogenital Warts: The HERCOLES Study
Carmen Lisboa, Irene Santo, Jacinta Azevedo, Luis Azevedo, Angela Pista, Camila Dias, Maria Joaõ Cunha
Human papillomavirus (HPV) infection is highly prevalent in the sexually active population. This study estimates the prevalence of HPV DNA in anal and oral samples from a cohort of men and women with incident anogenital warts. Anal and/or oral samples from 541 patients with anogenital warts were tested for 35 HPV genotypes using a PCR assay. The overall prevalence of anal HPV and oral HPV DNA was ...
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CLINICAL REPORT
Topical Steroid Withdrawal: A Case Series of 10 Children
Belinda Sheary
Concerns about topical steroid withdrawal are causing some patients to cease long-term topical corticosteroid therapy, however, little is known about the ensuing clinical outcomes. This qualitative case series studied 10 children whose parents stopped their chronic topical corticosteroid use and subsequently developed features typically reported in adults experiencing topical steroid withdrawal. P ...
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CLINICAL REPORT
Epidemiology of Depression in Patients with Psoriasis: A Nationwide Population-based Cross-sectional Study
Stephen Chu-Sung Hu, Gwo-Shing Chen, Hung-Pin Tu
The epidemiology of depression in patients with psoriasis has not been well defined in the Asian population. This study evaluated the epidemiological features of, and risk factors for, depression among patients with psoriasis in Taiwan. A nationwide population-based cross-sectional study was undertaken using the National Health Insurance Research Database. This study included 17,086 patients with ...
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QUIZ
Disseminated Small Papules on the Face: A Quiz
Victor Olsavszky, Cyrill Géraud, Moritz Felcht
Abstract is missing (Quiz)
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CORRESPONDENCE
Antipruritic vs. Antitumour Action of Aprepitant: A Question of Dose
Miguel Muñoz, Julio Parrilla, Marisa Rosso, Rafael Coveñas
Abstract is missing (Correspondence)
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ERRATUM
Erratum
Abstract is missing (Erratum)
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BOOK REVIEW
Facial Reconstruction after Mohs Surgery
John Paoli
Abstract is missing (Book review)
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BOOK REVIEW
Cutaneous Malignancies. A surgical perspective
Lisa Naysmith
Abstract is missing (Book review)
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BOOK REVIEW
Genetic Skin Disorders, 3rd edition
Anders Vahlquist
Abstract is missing (Book review)
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IN THIS ISSUE
Comment on: Quimp: A word meaning “quality of life impairment”
Pavel V. Chernyshov
Abstract is missing (In this Issue...)
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IN THIS ISSUE
Have you measured the patient’s quimp?
Magnus Lindberg
Abstract is missing (In this Issue...)
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