HIGHLIGHTS
Healthcare service utilization and epidemiology of AD in Israel
Guy Shalom, Meir Babaev, Khalaf Kridin, Yochai Schonmann, Amir Horev, Jacob Dreiher, Michal Shani, Shmuel Tiosano, Shani Fisher, Doron Comaneshter, Arnon D. Cohen
An increased burden of healthcare utilization across the entire spectrum of healthcare serveds is requried for atopic dermatitis patients compared with controls.
Eye complications during dupilumab treatment for severe AD
Lina U. Ivert, Carl-Fredrik Wahlgren, Lena Ivert, Maria Lundqvist, Maria Bradley
The risk of aderse events from the eyes and recurrence of herpes virus infections should be kept in mind when using dupilumab.
Swedish cost-utility analysis of calcipotriol/betamethasone dipropionate aerosol foam
Albert Duvetorp, Lars-Åke Levin, Emma Engerstedt Mattsson, Lasse Ryttig
The superior efficacy of Cal/BD foam over ointment led to fewer consultation visits, a decreased risk of progressing to second-line therapy, and lower total costs.
Modifiable risk-factors for keratinocyte cancers in Australia
Lina Maria Serna-Higuita, Simone L. Harrison, Petra Buttner, Margaret Glasby, Beverly A. Raasch, Angelika Iftner, Claus Garbe, Peter Martus, Thomas Iftner
Increasing age, lower academic qualifications, freckling during adolescence, solar lentiginous, propensity to sunburn and high-cumulative sun exposure increse the risk of keratinocyte cancer.
Itch in psoriasis
Radomir Reszke, Rafał Białynicki-Birula, Jacek C. Szepietowski
The majority of psoriatic patients experience chronic itch. This study evaluated the prevalence and clinical charactertistics of chronic itch in a cohort of psoriatic subjects.
Ixekizumab-induced psoriasiform eruption
Tomohiro Oiwa, Mafumi Fujita, Sawako Takase, Youichi Nishimura, Miyuki Ota, Kayo Okada, Takao Tachibana
The first case report of psoriasiform eruptions induced by ixekizumab.
COL17A1 variant alters splicing and causes JEB
Julia Hoffmann, Federica Casetti, Antonia Reimer, Juna Leppert, Gabriele Grüninger, Cristina Has
This study proves the pathogenicity of the hypomorphic COL17A1 variant associated with mild to moderate JEB. The in silico prediction of splicing alteration was confirmed by sequencing the mRNA; surprisingly the prediction with a relataively low score was experimentally proven.
This case series describes ten patients treated with dupilumab, where eye complications such as conjunctivitis were common, suggesting the importance of close collaboration with an ophthalmologist, especially among patients with severe, long-lasting AD and/or previous eye disease.
