Content » Vol 90, Issue 1


Pruritus in Cutaneous T-cell Lymphomas: Frequent, Often Severe and Difficult to Treat

Nicolas Meyer, Carle Paul, Laurent Misery
DOI: 10.2340/00015555-0789


Pruritus has a well-known association with Hodgkin’s disease and other nodal lymphomas; indeed it often rev­eals the disease. Pruritus is also an important symptom of cutaneous T-cell lymphomas. Lymphoma-associated itch is thus both frequent and severe, but its pathophysiology remains unclear. Few studies have evaluated the efficacy of therapeutic agents in the management of cutaneous T-cell lymphoma-related pruritus. The main objective of treatment remains disease control. Pruritus management is generally based on the physician’s experience. Treat­ment is very difficult, especially in Sézary syndrome. We present here management strategies for cutaneous lymph­oma-associated pruritus.


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