Content » Vol 97, Issue 5

Investigative Report

ItchApp©: An App-based eDiary for Assessment of Chronic Pruritus in Clinical Trials

Marvin Gernart, Athanasios Tsianakas, Claudia Zeidler, Claudia Riepe, Nani Osada, David Pihan, Sonja Ständer
DOI: 10.2340/00015555-2602

Abstract

Performing a reliable assessment of chronic pruritus remains a challenge. Electronic diaries are often used, but many of the scales have not been validated. ItchApp© was developed for Android smartphones in order to address this lack. A total of 40 subjects with chronic pruritus completed questionnaires both on paper and with ItchApp© (verbal rating scale, numerical rating scale, dynamic pruritus score) in order to validate the software application. Strong correlations were found for test–retest reliability (intraclass correlation coefficient: 0.865–0.977) and convergent validity (Spearman’s r: 0.442–0.924). A feasibility questionnaire for ItchApp© revealed a high level of user friendliness and compliance. This was confirmed in a randomized controlled trial with 68 subjects, for which the clinically important difference in the numerical rating scale values for ItchApp© was calculated (2.61 points). In summary, ItchApp© is a recently developed eDiary that can provide experts with a reliable evaluation of patients with chronic pruritus. It will be made available for future clinical trials.

Significance

Supplementary content

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