Content » Vol 62, Issue 1

Lichen nitidus: electron microscopic and immunofluorescence studies

J. Clausen, F.K. Jacobsen, F. Brandrup
DOI: 10.2340/00015555621519


Skin biopsies from a patient suffering from lichen nitidus were studied by electron microscopy and immunofluorescence studies. Complete disintegration of the stratum basale in the central area of the lesion and signs of acantholysis in the border area were found. In the central part of the lesion the dermo-epidermal junction was severely damaged in most places. In the dermal infiltrate, macrophages and lymphocytes were found with a considerable representation of S?©zary cells, not previously reported in lichen nitidus. The ultrastructural changes are identical with those found in lichen planus. No in vivo bound immunoglobulins, fibrinogen, or complement C3 were found.


Supplementary content


Not logged in! You need to login/create an account to comment on articles. Click here to login/create an account.