Content » Vol 64, Issue 5

Phenotypic characterization of skin-infiltrating cells in pagetoid reticulosis by monoclonal antibodies

Gonzalez M, Martin-Pascual M, San Miguel J, Caballero MD, López Borrasca A.
DOI: 10.2340/0001555564421424


The immunological characterization of the infiltrating cells in a patient with a disseminated form of Pagetoid reticulosis (PR) was carried out-in histological section and cell suspensions--by means of a panel of monoclonal antibodies and classical markers (E-rosette and surface immunoglobulins (SIg]. Most of the infiltrating cells were seen to be mature T-lymphocytes with a suppressor/cytotoxic phenotype (T11+, T3+, T8+, T4-). The results suggest that this variant of PR represents a special histological type of cutaneous T cell lymphoma.


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