Content » Vol 65, Issue 2

Plasma 5-S-cysteinyldopa concentrations in oculocutaneous albinism

Nimmo JE, Hunter JA, Percy-Robb IW, Jay B, Phillips CI, Taylor WO.
DOI: 10.2340/0001555565169171

Abstract

5-S-cysteinyldopa concentrations were determined by high-pressure liquid chromatography and electrochemical detection in plasma from normally pigmented patients and patients with oculocutaneous albinism, both tyrosinase-positive and tyrosinase-negative. The plasma 5-S-cysteinyldopa concentrations were similar in all three groups, suggesting that 5-S-cysteinyldopa can be produced by mechanisms which do not involve tyrosinase.

Significance

Supplementary content

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