Content » Vol 65, Issue 5

Oxidation of dopa in human albinism

Carstam R, Hansson C, Krook G, Rorsman H, Rosengren E, Wirestrand LE.
DOI: 10.2340/0001555565435437


The urine of an albino woman contained small quantities of 5-S-cysteinyldopa; 6-hydroxy-5-methoxyindole-2-carboxylic acid, a melanin precursor metabolite, was lacking. The 5-S-cysteinyldopa excretion observed may reflect non-specific oxidation of dopa. Two other albino patients showed normal values for the excretion of 5-S-cysteinyldopa and of 6-hydroxy-5-methoxyindole-2-carboxylic acid.


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