Content » Vol 67, Issue 3

HLA-B39 and the axial type of psoriatic arthritis

Crivellato E, Zacchi T.
DOI: 10.2340/0001555567249250


The frequency distribution of HLA-B38 and HLA-B39 was studied in a group of 50 unrelated psoriatic arthritis patients. A high increase of HLA-B39 was noted in the subgroup with axial arthropathy. All B39 positive patients presented with spondylitis and/or sacroiliitis. The hypothesis is formulated that HLA-B39 may discriminate a genetic subset of psoriatic arthritis characterized by a particular susceptibility to develop axial involvement.


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