Content » Vol 69, Issue 5

Transient acantholytic dermatosis associated with lymphomatous angioimmunoblastic lymphadenopathy

Zelickson BD, Tefferi A, Gertz MA, Banks PM, Pittelkow MR.
DOI: 10.2340/0001555569445448


Transient acantholytic dermatosis is a papulovesicular cutaneous eruption first described in 1970. There have been subsequent reports of similar disorders occurring in patients with malignancy. Angioimmunoblastic lymphadenopathy with dysproteinemia is a disorder characterized by an acute onset of generalized lymphadenopathy associated with fever, malaise, pruritus, night sweats, and hepatosplenomegaly. The patient described had a papular acantholytic dermatosis associated with the development of angioimmunoblastic lymphadenopathy with dysproteinemia-like T-cell lymphoma. The cutaneous manifestations of angioimmunoblastic lymphadenopathy with dysproteinemia are discussed.


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