Content » Vol 73, Issue 1


The polymerase chain reaction and dermatology. A new technique with important implications for the study of skin inflammation and for diagnostic tests of dermatological disorders.

Paludan K, Thestrup-Pedersen K.
DOI: 10.2340/000155557316


The polymerase chain reaction is a powerful and versatile tool for the analysis of nucleic acids. Through a reaction imitating in vivo DNA replication, a defined fragment of DNA is repeatedly replicated by a DNA polymerase in an exponential manner. Such selective amplification of a sequence of interest has created new possibilities in molecular biology and related sciences. The basic principle and some of its variations and applications for both qualitative and quantitative analyses of potential interest to dermatologists are described.


Supplementary content


Not logged in! You need to login/create an account to comment on articles. Click here to login/create an account.