Q-switched ruby laser application is safe and effective for the management of actinic lentigo (topical glycolic acid is not).
Kopera D, Hohenleutner U, Landthaler M
A study was designed to evaluate the effectiveness of single q-switched ruby laser exposure to erase actinic lentigo. A peeling fluid containing glycolic acid designed to treat lentigines was evaluated comparatively. Ten female patients presenting with actinic lentigines on the forearms and dorsal aspects of their hands were treated with the q-switched ruby laser on the right side. Single ruby laser irradiation of actinic lentigines on the dorsal aspects of forearms and hands caused transient crusting due to exfoliation of the epidermal surface, which generally lasted for 2 weeks. Four weeks after treatment total fading of the lesions was evident. Topical application of peeling fluid applied on the left forearms caused burning sensations, local irritation and superficial scaling but could not clear the lentigines. A single course of q-switched ruby laser exposure is safe and efficient for the management of actinic lentigines, as it completely clears these obvious signs of aging. Topical treatment of lentigines using a commercial peeling solution leads to moderate or severe irritation and is ineffective.