Content - Volume 62, Issue 2

All articles

In situ characterization and counting of mononuclear cells in lesions of different clinical forms of psoriasis
Bjerke JR.
Mononuclear cells in the dermis were characterized and counted in cryostat sections of lesional skin from 34 patients with various clinical forms of psoriasis. T lymphocytes were detected with F(ab´)2 preparation of rabbit IgG against human T lymphocytes and acid alpha-naphthyl acetate esterase (ANAE) activity as histochemical marker. The ANAE method was also used for the detection of macrophages ...
Pages: 93-100
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Local panatrophy with linear distribution: a clinical, ultrastructural and biochemical study
J. Serup, K. Weismann, T. Kobayasi, T. Ammitzbøll, R. Møller
A young female with local panatrophy of the right-side extremities affecting all mesodermal layers--dermis, subcutaneous tissue, muscles, and bone--is described. The atrophies were strictly linear. Ultrastructurally, collagen fibrils of the reticular dermis from the atrophic area consisted of two types, a large population of fibrils with decreased diameter and round cut-surface, and a small popula ...
Pages: 101-105
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Effects of sex steroids on human skin in organ culture
R. Tammi
Histometric and autoradiographic methods were applied to investigate the actions of sex hormones on the cultured epidermis of post-menopausal women. Both testosterone and progesterone at the concentration of 10(-9)-10(-7) mol/l enhanced the keratinization of the epidermal cells during the 7-day culture. The numbers of the granular cells were increased by both of these hormones and the transit time ...
Pages: 107-112
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Ultrastructure of Cryptococcus neoformans
H. Hino, K. Takizawa, G. Asboe-Hansen
The ultrastructure of C. neoformans was studied in two cases of cutaneous cryptococcosis. Extracellular and intracellular fungi were observed. Their capsules and clear zones were thick and distinct, but their cytoplasmic organelles were not obvious. In macrophages, a few stages of fungal degeneration could be observed. It could not be ascertained whether the changes were caused by anti-fungal drug ...
Pages: 113-117
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Cutaneous lymphocytomas: clinical and histological aspects
G.L. Wantzin, K. Hou-Jensen, M. Nielsen, J. Petri, K. Thomsen
25 cases of cutaneous lymphocytoma were reviewed, of which 13 were benign lymphocytoma of the skin and 15 lymphocytic infiltration of the skin (Jessner). The clinical diagnosis benign lymphocytoma of the skin was in agreement with the histology, except in 2 patients where lymphocytic infiltration of the skin (Jessner) was the most likely clinical diagnosis. Of the 15 patients treated, 8 went into ...
Pages: 119-124
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Colloid bodies in dermatoses other than lichen planus
A. Johannesson, H. Hammar, KG. Sundqvist
In a previous study on lichen planus the morphology and significance of the colloid bodies were discussed (13). In the present study a description is given of 30 dermatoses with colloid bodies, observed among unselected patients. The colloid bodies develop as a result of damage to the epithelium caused by circulatory disorders with subsequent hypo- or anoxia. Lichenoid cell infiltration into the c ...
Pages: 125-131
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Effects of short-wave ultraviolet light (UVB) on delayed hypersensitivity in the guinea pig
J. Austad, N.J. Mørk
Guinea pigs, previously sensitized to dinitrochlorobenzene (DNCB), were exposed to varying doses of UVB radiation on the right flank for a period of 12 days. The response to an elicitation dose of DNCB was diminished in the irradiated skin immediately after UV treatment. This effect was dose-dependent. No reduction in the response could be demonstrated in unexposed skin. One week after UVB treatme ...
Pages: 133-136
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Influence of ultraviolet light on itch and flare reactions in human skin induced by histamine and the histamine liberator compound 48/80
B. Fjellner, Ö. Hägermark
The itch and flare responses induced by intradermal injection of histamine and the histamine liberator compound 48/80 were studied in healthy volunteers before and after exposure to UVB, UVA or PUVA administered 2-3 times weekly for 4 weeks. All three modalities were found to inhibit the responses induced by compound 48/80. The degree of tanning was most pronounced after PUVA and weakest after UVB ...
Pages: 137-140
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Herpetiform eruption with leukocytoclasis: a distinctive clinico-pathological variety of erythema multiforme
Ferrándiz C, Peyrí J, Henkes J, Romagosa V.
Six patients are described who experienced a prodromal period suggesting an infective process, followed by a distinctive polymorphous cutaneous eruption. The most striking lesion, present in all of them and giving the eruption a distinctive herpetiform appearance, included closely grouped vesicles resting on an erythematous base. Histopathological examination of these lesions showed features of de ...
Pages: 141-146
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Erythema craquelé provoked by corticosteroids on normal skin
Björnberg A.
The provocation of erythema craquel?© after cessation of long-term continuous steroid application to normal skin was investigated in 58 healthy subjects, usually under occlusion. No correlation was demonstrated between the erythema craquel?© and skinfold thickness measured with the Harpenden technique.
Pages: 147-151
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Sensitization capacity of polyester methacrylate in ultraviolet curing inks tested in the guinea pig
B. Björkner
One of the prepolymers used in Ultraviolet (UV) curing ink formulations is acrylated polyester. The prepolymer investigated is a dimethacrylated polyester, thus a saturated polyester terminated with methacrylic groups. In conventional UV-curing coatings the prepolymer commonly used is an unsaturated polyester. Three of six workers with dermatitis from UV-curing inks in printing plants had positive ...
Pages: 153-154
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HLA antigens in discoid lupus erythematosus
M.M. Tongio, J Fersing, G Hauptmann, S Mayer, D Grange, M Samsoen, E Groshans
HLA-A, B, C and Bf typing was performed in 55 cases of Discoid Lupus Erythematosus (DLE). When both the sex and age of the patient at the onset of the disease were taken into consideration (group I under 40 years, group II over 40), the following increases in antigen frequency were observed: group I: A2 in women, B5, A10 in men; group II: Aw19.2 in women, B8 in both sexes. Nevertheless, if the pro ...
Pages: 155-157
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Occurrence of Trichophyton tonsurans infections in the Danish island of Funen
EK Foged, B Sylvest
During the period from 1977 to 1980 eleven cases of T. tonsurans infections were diagnosed in the Mycology Laboratory, Department of Dermatology and Venereology, Odense University Hospital, Denmark. All patients were adults and none had tinea capitis. Five patients had tinea pedis, 5 tinea ungvium, 2 tinea cruris, one tinea manuum, and one tinea glabrosa.
Pages: 159-162
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Oral retinoid in combination with bleomycin, cyclophosphamide, prednisone and transfer factor in mycosis fungoides
H Zachariae, E Grunnet, K Thestrup-Pedersen, L Molin, H Schmidt, F Starfelt, K Thomsen
Oral retinoids seem to have been of great benefit in a non-randomized study on advanced mycosis fungoides using two different chemotherapy regimens, one with retinoid, the other without. Both groups also received a 3-drug chemotherapy with bleomycin, cyclophosphamide and prednisone. Complete remission including all signs of lymph-node involvement was found in 8 of 10 patients of the retinoid treat ...
Pages: 162-164
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Effect on oral leukoplakia of reducing or ceasing tobacco smoking
B. Roed-Petersen
Oral leukoplakia patients who were smokers were asked to give up their smoking habits. It was found that leukoplakias present in persons with smoking habits might be reversible, when the smoking habit was reduced or given up. Leukoplakias which were not reversible could possibly be of the same idiopathic type as leukoplakias in non-smokers.
Pages: 164-167
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Inhibited proliferation of human scleroderma skin fibroblasts and rheumatoid synovial cells with griseofulvin in vitro
GC Priestley, JC. Brown
Griseofulvin at 2-17 micrograms/ml in in vitro inhibited the proliferation of scleroderma skin fibroblasts and rheumatoid synovial cells. The inhibition was concentration-dependent, with little difference between the two types of cells. Mean ID50 values from the four strains of each group were 9.2 for fibroblasts and 9.5 for synovial cells. The results show that griseofulvin at therapeutic concent ...
Pages: 167-169
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Exanthema fixum due to ultraviolet radiation
J. Langeland
No abstract available.
Pages: 169-171
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Propylthio-uracil-induced cutaneous vasculitis
M Gammeltoft, JK. Kristensen
Three cases of cutaneous vasculitis, leukocytopenia and arthralgia, presumably caused by the antithyroid drug Propylthio-uracil, are presented. Acute vasculitis of the superficial and deep dermal blood vessels accompanied by vascular thrombus formation were found in biopsy specimens. Direct immunofluorescence studies demonstrated deposits of C3 or IgM and C3 in the walls of vessels in affected and ...
Pages: 171-173
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Malignant clear cell hidradenoma: a case report
DB Czarnecki, I Aarons, JP Dowling, B Lauritz, P Wallis, EH Taft
A 73-year-old man developed a malignant clear cell hidradenoma on the nose. Although it was treated solely with diathermy and curettage it did not recur. These rare tumours are histologically malignant but do not always behave aggressively. In some patients local growth and recurrence may occur, while in others the tumour metastasizes widely. There is no way of predicting how these tumours will be ...
Pages: 173-176
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The Klippel Trenaunay Weber Syndrome presenting with cutaneous bleeding
SJ Adams, WJ. Cunliffe
A patient with the Klippel Trenaunay Weber syndrome presented with prolonged bleeding from the finger tips during strenuous exercise. Tissue fibrinolysis studies showed increased fibrinolytic activity suggesting that the blood vessels in the affected limb may be functionally as well as anatomically abnormal.
Pages: 176-178
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Palmo-plantar keratoderma associated with carcinoma of the bronchus
FA Kerdel, DM. MacDonald
No abstract available.
Pages: 178-180
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Cartilaginous nevus on the glabella
S Sayama, H. Tagami
Cartilaginous nevus usually occurs in front of the auricle as an accessory auricle and much less frequently on the cheek or anterior part of the neck. We report a case of cartilaginous nevus found on an unusual location, The glabella of the face, in an otherwise normal newborn girl. We think that it was a remnant of the branchial cartilage derived from the first pharyngeal arch of embryonic life.
Pages: 180-181
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A novel wax stick preparation of anthralin
RJ Chalmers, JM Marks, S Shuster
A new wax formulation of anthralin was compared with anthralin as used in the Ingram regimen for the treatment of chronic discoid psoriasis. In 16 out-patients 12 of the 13 who responded to the Ingram regimen also showed a satisfactory response to the wax preparation. The latter could be applied more rapidly and simply and may thus have a useful place in the domestic management of chronic psoriasi ...
Pages: 181-182
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Aspirin iin the management of necrobiosis lipoidica
K Karkavitsas, JA Miller, PM Dowd, JD Kirby
No abstract available.
Page: 183
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