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Content - Volume 70, Issue 6

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Reactive changes in the Langerhans' cells of human skin caused by occlusion with water and sodium lauryl sulphate
Mikulowska A
Human skin was patch tested with sodium lauryl sulphate or with water only for 48 h and biopsied immediately and after 24 h, then analyzed by immunocytochemistry and electron microscopy. Sodium lauryl sulphate produced a decrease in the number of epidermal Langerhans' cells and an increase in dermal Langerhans' cells, with individual variations. The 48-h water occlusion controls showed only slight ...
Pages: 468-473
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Expression of protein kinase C isozyme in human Langerhans' cells
Koyama Y, Fukaya Y, Ueda H, Hachiya T, Hagiwara M, Hidaka H, Marunouchi T.
Protein kinase C is a key molecule controlling signal transduction into the cell. We recently reported that protein kinase C II isoenzyme, but neither I nor III isozyme, was expressed in epidermal Langerhans' cells of the adult mouse, and that none of these isozymes was detected in keratinocytes. In this study, we examined the expression of protein kinase C isozymes in human Langerhans' cells in v ...
Pages: 500-502
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