Content

Content - Volume 74, Issue 2

Editor's choice in this issue

All articles

INVESTIGATIVE REPORT
Oral hairy leukoplakia: pathogenetic aspects and significance of the lesion.
Brehmer-Andersson E, Lucht E, Lindskog S, Ekman M, Biberfeld P
Oral hairy leukoplakia in HIV-seropositive persons is considered as a highly serious sign and places the patient in the AIDS-related complex group according to the classification recommended by the Centers for Disease Control. Epstein-Barr virus (EBV) is thought to be the cause. Based on the investigation of 14 of our own cases and a review of the literature, we conclude that so called hairy leuko ...
Pages: 81-89
Abstract  PDF
INVESTIGATIVE REPORT
Serum selenium in melanoma and epidermotropic cutaneous T-cell lymphoma.
Deffuant C, Celerier P, Boiteau HL, Litoux P, Dreno B
As several studies have demonstrated a relationship between decreased serum selenium concentrations and the frequency of certain cancers, we studied these concentrations in two kinds of cutaneous tumour cancer: melanoma and epidermotropic cutaneous lymphoma. We first determined the predictive value of the selenium assay for the frequency of recurrences in stage I and II melanomas and then consider ...
Pages: 90-92
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INVESTIGATIVE REPORT
HLA-DR positive epidermal Langerhans' cells in liver cirrhosis and immunosuppressed liver transplanted patients.
Gilhar A, Enat R, Baruch Y
The aim of the present study was to evaluate the number of Langerhans' cells (LC) in immunosuppressed liver transplanted patients, compared to patients with liver cirrhosis and healthy volunteers. The detection of LC was performed in the epidermal sheet of each patient by using indirect immunoperoxidase and ATPase staining. A significant reduction in the number of LC was found in the liver transpl ...
Pages: 93-94
Abstract  PDF
INVESTIGATIVE REPORT
Ki-67 and p53 expression in cutaneous Bowen's disease: an immunohistochemical study of fixed-embedded tissue sections.
Szekeres G, De Giacomoni P
The monoclonal Ki-67-specific MIB-1 and p53 protein-specific DO-1 antibodies were used to identify proliferating cell fractions on microwave-pretreated paraffin sections of 7 cutaneous Bowen's disease specimens. A high Ki-67 score was characteristic of all cases examined, and significant p53-positivity was seen in 4 cases. In the peritumoral, histologically normal epidermis, Ki-67- and p53-positiv ...
Pages: 95-97
Abstract  PDF
INVESTIGATIVE REPORT
DF3 (CA15-3) antibody as a marker of cutaneous adnexal tumors.
Yasui S, Ando I, Kukita A, Hino H, Ohara K
DF3(CA15-3) monoclonal antibody detects the 20 amino acid sequence of epithelial mucin. In normal cutaneous tissue DF3 antibody exhibits strong and constant positive reactivity with sebaceous and secretory segments of eccrine and apocrine sweat glands. All epidermal tumors are DF3 negative but poorly differentiated squamous cell carcinoma. Various adnexal tumors such as eccrine hidrocystoma, tubul ...
Pages: 98-100
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INVESTIGATIVE REPORT
Expression of the alpha 6 beta 4 integrin by squamous cell carcinomas and basal cell carcinomas: possible relation to invasive potential?
Rossen K, Dahlstrøm KK, Mercurio AM, Wewer UM
We have studied the expression of alpha 6 beta 4 integrin, a carcinoma laminin receptor in ten squamous cell carcinomas (SCCs) and ten basal cell carcinomas (BCCs) of the skin in order to examine whether changes in alpha 6 beta 4 integrin expression may be related to invasive and metastatic potential. Monoclonal antibodies specific for each subunit were applied on cryosections, using a three step ...
Pages: 101-105
Abstract  PDF
INVESTIGATIVE REPORT
Somatostatin immunoreactive cells in lesional psoriatic human skin during peptide T treatment.
Johansson O, Hilliges M, Talme T, Marcusson JA, Wetterberg L
Peptide T has been shown to be an effective treatment in psoriasis. The mechanism through which peptide T works in psoriasis is at present unknown. Furthermore, a clearance of psoriasis has also been registered using the inhibitory peptide somatostatin. These observations all focus on the fact that peptide T, somatostatin, and/or other peptides, might provide a clue to understanding the etiology a ...
Pages: 106-109
Abstract  PDF
INVESTIGATIVE REPORT
Lowered peripheral resistance in arteries of legs with venous ulcer.
Malanin K, Haapanen A, Havu V
In the literature there is disagreement concerning the existence of arteriovenous shunting in legs with venous ulcer(s). The aim of this study was to find out if there are differences in resistance in the arteries of ulcer legs and non-ulcer legs and if it is possible to investigate this with a non-invasive Doppler method. Eleven patients, aged 34-87 years, with venous ulcer only in one leg, were ...
Pages: 110-112
Abstract  PDF
INVESTIGATIVE REPORT
Histamine effect on human cutaneous blood flow: regional variations.
Tur E, Aviram G, Zeltser D, Brenner S, Maibach HI
Different reactivities of small blood vessels to the histamine released by exogenous and endogenous substances may play a role in the regional variations of the elicited cutaneous response. To study the regional dependence of cutaneous blood flow in response to histamine, the compound was administered intradermally (prick introduction), thereby bypassing the spatially dependent penetration process ...
Pages: 113-116
Abstract  PDF
INVESTIGATIVE REPORT
A possible new incoherent lamp for photodynamic treatment of superficial skin lesions.
Szeimies RM, Hein R, Bäumler W, Heine A, Landthaler M
Since coherence of laser light is not necessary for photodynamic therapy of skin lesions, attempts have been made to construct incoherent lamps. A recent development is the PDT 1200 (Waldmann Medizintechnik/Germany), a light source consisting of a 1200 watt metal halogen lamp. Emission of 600 to 800 nm radiation is achieved by using cut-off filters. Power density can be varied from 30 mW/cm2 to 20 ...
Pages: 117-119
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CLINICAL REPORT
High frequency of thyroid dysfunction in patients with vitiligo.
Hegedüs L, Heidenheim M, Gervil M, Hjalgrim H, Høier-Madsen M
An association between vitiligo and autoimmune thyroid disease has previously been suspected. This study was undertaken to determine the frequency and type of thyroid disease in 35 consecutive patients admitted because of vitiligo compared with a matched control group. One or more signs of thyroid disease was demonstrated in 15 out of 35 patients (43%) with vitiligo, as compared to 7 out of 35 (20 ...
Pages: 120-123
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CLINICAL REPORT
A survey of atopic diseases among school children in Sør-Varanger community. Possible effects of subarctic climate and industrial pollution from Russia.
Dotterud LK, Kvammen B, Bolle R, Falk ES
The occurrence of atopic diseases in school children in the community of Sør-Varanger was studied on the basis of a questionnaire sent to the parents of all the 575 children aged 7-12 years. 551 children (95.8%), 266 girls and 285 boys, completed the questionnaire. Atopic diseases were reported to be present or to have occurred in 249 (45.2%) of the 551 children, more frequently in girls (50.4%) ...
Pages: 124-128
Abstract  PDF
CLINICAL REPORT
Infra-auricular fissures in atopic dermatitis.
Tada J, Toi Y, Akiyama H, Arata J
Retro-auricular or auricular dermatitis in atopic dermatitis (AD) is common and important for the diagnosis of AD in infancy and even in adulthood. Particularly, "infra-auricular fissures", acute eczematous changes like fissures at the adhesive junction of ear lobes, seem to be prominent features for the diagnosis of AD. Of 137 patients with AD, 81.8% showed present or past existence of infra-auri ...
Pages: 129-131
Abstract  PDF
CLINICAL REPORT
Erythema multiforme during GM-CSF therapy.
Stasi R, Gatti S, Perrotti A, Orlandi A, Spagnoli LG, Papa G
A 52-year-old Caucasian man treated with granulocyte-macrophage colonystimulating factor (GM-CSF) developed a cutaneous eruption on legs and ankles with clinical and histologic features of erythema multiforme. Laboratory studies indicated that the eruption occurred at the time of peripheral blood lymphocyte recovery and that it was coincidental with serum peaks of interleukin-1 (IL-1), interleukin ...
Pages: 132-134
Abstract  PDF
CLINICAL REPORT
Dyschromatosis symmetrica hereditaria associated with idiopathic torsion dystonia. A case report.
Patrizi A, Manneschi V, Pini A, Baioni E, Ghetti P
The authors report a case of a family in which a diagnosis of dyschromatosis symmetrica hereditaria was established by a clinical pattern of cutaneous lesions and by assessment of cellular DNA repair synthesis. The skin lesions were characterized by a mixture of hyperpigmented and hypopigmented macules and were localized on the back of the feet of three patients (two male brothers and one sister). ...
Pages: 135-137
Abstract  PDF
CLINICAL REPORT
Leukocytoclastic vasculitis: another coumarin-induced hemorrhagic reaction.
Tamir A, Wolf R, Brenner S
A 67-year-old male developed a hemorrhagic eruption 4 weeks after initiation of coumarin therapy. Examination revealed a well-demarcated, purple patch with a central hemorrhagic bulla on the anterior aspect of the leg, surrounded by small petechiae. Histological examination of the purple plaque revealed leukocytoclastic vasculitis. It is suggested that leukocytoclastic vasculitis be considered in ...
Pages: 138-139
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CLINICAL REPORT
Steroid injection therapy for pseudocyst of the auricle.
Miyamoto H, Oida M, Onuma S, Uchiyama M
In our clinic, we encountered 8 patients with pseudocyst of the auricle during a 6-year period from 1987 to 1992 and injected steroid solution locally into the pseudocysts. Three of these patients had no recurrences and 4 were treated successfully after 1-3 recurrences. In only one case was this therapy ineffective. After 11 injections, which resulted in permanent deformity of the auricle, the pat ...
Pages: 140-142
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CLINICAL REPORT
Weekly treatment of psoriasis with a hydrocolloid dressing in combination with triamcinolone acetonide. A controlled comparative study.
van de Kerkhof PC, Chang A, van der Walle HB, van Vlijmen-Willems I, Boezeman JB, Huigen-Tijdink R
In a within subject comparison, the efficacy and the tolerability of topical treatment with triamcinolone acetonide under a hydrocolloid dressing were compared with triamcinolone acetonide monotherapy, monotherapy with hydrocolloid dressing and triamcinolone acetonide under plastic occlusion. The clinical efficacy of hydrocolloid dressing as a monotherapy and the pronounced clinical efficacy of th ...
Pages: 143-146
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LETTER TO THE EDITOR
Vitiligo.
Falabella R
Comment on - Autotransplantation in vitiligo: treatment with epidermal grafts and cultured melanocytes. [Acta Derm Venereol. 1993] - Repigmentation of vitiligo by transplantation of cultured autologous melanocytes. [Acta Derm Venereol. 1993]
Pages: 147-148
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LETTER TO THE EDITOR
Anthropophilic transmission of blistering distal dactylitis.
Zemtsov A, Paulger B, Veitschegger M
Pages: 148-149
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LETTER TO THE EDITOR
The case of the mercury heart
Muzio GF, Guarrera M, Rongioletti F
Comment in The case of the mercury heart. [Acta Derm Venereol. 1995]
Pages: 149-150
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LETTER TO THE EDITOR
Kallin's syndrome: two more cases
Nielsen PG
Pages: 150-152
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LETTER TO THE EDITOR
Localized pachydermodactyly in a woman
Bardazzi F, Fanti PA, de Padova MP, Varotti C
Pages: 152-153
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LETTER TO THE EDITOR
Alopecia areata occurring in a patient receiving systemic cyclosporin A.
Roger D, Charmes JP, Bonnetblanc JM
Pages: 154-154
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LETTER TO THE EDITOR
Cutaneous eyebrow metastasis in a patient with primary gastric adenocarcinoma.
Peris K, Cerroni L, D'Alessandro I, Chimenti S
Pages: 154-155
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LETTER TO THE EDITOR
Nickel, atopy, irritant reactivity and statistical pitfalls.
Schnuch A
Comment on Irritant reactivity is a better risk marker for nickel sensitization than atopy. [Acta Derm Venereol. 1993]
Pages: 156-156
Abstract  PDF