Content

Content - Volume 80, Issue 6

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GUEST EDITORIAL
This article does not have an abstract.
Pages: 401-403
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LETTER TO THE EDITOR
Investigation of Cytomegalovirus and Human Herpes Viruses 6 and 7 as Possible Causative Antigens in Psoriasis
Psoriasis is probably a T-cell-mediated autoimmune disease. Infectious models of autoimmune diseases have been proposed and in psoriasis, it has been suggested that there may be molecular mimicry between streptococcal antigens and epidermal keratins. The immunological profile of stable psoriasis plaques suggests, however, that viral antigens may be important. We investigated, using polymerase cha ...
Pages: 404-406
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LETTER TO THE EDITOR
Proliferation of T Lymphocytes from Atopic Dermatitis Skin is Enhanced upon anti-CD3, Reduced upon Mitogen and Superantigen, and Negligible upon Tuberculin Stimulation
Knowledge about the nature of lymphocytes infiltrating atopic dermatitis skin is restricted to allergen-specific T cells. We investigated the proliferative capacities of T lymphocytes cultured in an antigen-independent way from biopsies of atopic dermatitis skin. When compared with peripheral blood mononuclear cells (PBMC) from healthy donors or atopic dermatitis patients, the skin-homing lymphoc ...
Pages: 407-411
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LETTER TO THE EDITOR
Skin-identical Lipids Versus Petrolatum in the Treatment of Tape-stripped and Detergent-perturbed Human Skin
The cutaneous permeability barrier is localized to the stratum corneum interstices and is mediated by lamellar bilayers enriched in cholesterol, free fatty acids and ceramides. Topically applied lipids may interfere with the skin barrier function and formulations containing "skin-identical lipids" have been suggested to facilitate normalization of damaged skin. The aim of the present study was to ...
Pages: 412-415
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LETTER TO THE EDITOR
Tumour Necrosis Factor-a Does Not Influence Proliferation and Differentiation of Healthy and Psoriatic Keratinocytes in a Skin-equivalent Model
Tumour necrosis factor-α (TNF-α) has been implicated in the pathogenesis of psoriasis. Its effect on keratinocytes from healthy and psoriatic skin was investigated. The keratinocytes were co-cultured with healthy and psoriatic fibroblasts in skin equivalents and grown in a serum-free medium for 15 days. TNF-α was added, or not, on day 12. The expression of differentiation and proliferation mar ...
Pages: 416-420
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LETTER TO THE EDITOR
Experimental Candida albicans Lesions in Healthy Humans: Dependence on Skin pH
The addition of suspensions of Candida albicans cells under occlusion to the left and right forearms, buffered at 2 different pH levels (6.0 and 4.5), resulted after 24 h in unilateral or bilateral lesions in 14 of 15 volunteers. The resulting skin-surface pH was 5.7 ± 0.3 and 5.1 ± 0.2, respectively. The lesions were more pronounced on the arm with the higher pH in all 14 subjects who reacted. ...
Pages: 421-424
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LETTER TO THE EDITOR
Is Helicobacter pylori Infection Associated with Chronic Urticaria?
There have been controversial reports of an elevated prevalence rate of Helicobacter pylori infection in chronic urticaria patients. Furthermore, in some studies remission of chronic urticaria has been reported after eradication of H. pylori. The aim of this investigation was to evaluate the prevalence of H. pylori infection among chronic urticaria patients and to study the e ...
Pages: 425-426
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LETTER TO THE EDITOR
Peptic Ulcer and Helicobacter pylori in Patients with Lichen Planus
The aetiology of lichen planus is unknown, but it is often connected with infections. In recent years peptic ulcer disease has also been closely linked with an infectious agent, Helicobacter pylori. A case-control study was conducted in 78 patients with lichen planus to find out a previous history of peptic ulcer disease, using a questionnaire and a medical record review. Patients were als ...
Pages: 427-429
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Health-related Quality of Life in Patients with Psoriasis and Atopic Dermatitis Measured with SF-36, DLQI and a Subjective Measure of Disease Activity
Lena Lundberg, Magnus Johannesson, Margareta Silverdahl, Christina Hermansson, Magnus Lindberg
The impact of skin diseases on health-related quality of life is considerable. It is important to quantify the patient's perspective of the severity of their disease. Health-related quality of life was measured in 366 patients with skin diseases attending the dermatology outpatient clinic in Uppsala, Sweden, from November 1996 to December 1997, with 1 generic (SF-36) and 1 disease-specific (DLQI) ...
Pages: 430-434
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LETTER TO THE EDITOR
In vivo Testing of the Protection Provided by Non-latex Gloves against a 2-Hydroxyethyl Methacrylate-containing Acetone-based Dentin-bonding Product
In dentistry, allergic contact dermatitis to acrylates and allergic contact urticaria to latex are important occupational hazards. There is a need to identify non-latex gloves which are suitable for dental work but at the same time provide adequate protection against acrylate monomers. In a previous study, a new open-chamber system was used for testing the in vivo protection of 6 different ...
Pages: 435-437
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LETTER TO THE EDITOR
Increased Basic Fibroblast Growth Factor Levels in Serum and Blister Fluid from Patients with Vitiligo
Basic fibroblast growth factor (bFGF) is a pleiotropic growth factor which has a high capacity for stimulating normal melanocyte proliferation and suppressing melanogenesis. The close and complicated relationship between bFGF, melanocyte proliferation and melanogenesis raises the theoretical possibility that bFGF may also be involved in the pathomechanism leading to vitiligo. The aim of this stud ...
Pages: 438-439
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CLINICAL REPORT
Analysis of the CDKN2A and CDK4 Genes and HLA-DR and HLA-DQ Alleles in Two Spanish Familial Melanoma Kindreds
Some confusion exists in the literature about which criteria should be used to define familial melanoma. This could explain the different reported frequencies of mutations in predisposing genes, mostly CDKN2A, in these patients. This study evaluated the human leucocyte antigen (HLA) class II genotype and the presence of mutations in CDKN2A and CDK4 genes in 2 families with very different clinical ...
Pages: 440-442
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CLINICAL REPORT
Immunohistological Distribution of Stem Cell Factor and Kit Receptor in Angiosarcoma
Angiosarcoma is a rare neoplasm, originating in the endothelium, which has a poor prognosis because of a high potential for metastasis. Although little is known about the pathogenesis of angiosarcoma, angiogenic cytokines are suggested to play an important role in tumor progression in a paracrine/autocrine fashion. Mast cells contain several mediators or cytokines influencing vascularization. To ...
Pages: 443-445
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LETTERS TO THE EDITOR
This article does not have an abstract.
Pages: 446-458
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BOOK REVIEWS
This article does not have an abstract.
Page: 471
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