Content

Content - Volume 81, Issue 1

All articles

EDITORIAL
Editorial News and Some Highlights in This Issue
Anders Vahlquist, Lennart Juhlin, Torbjörn Egelrud
This article does not have an abstract.
Pages: 1-2
Abstract  PDF
INVESTIGATIVE REPORT
Cytokine Expression of Skin T-lymphocytes from Patients with Atopic Dermatitis
Naoyuki Higashi, Karen Bang, Borbala Gesser, Marianne Lund, Kristian Thestrup-Pedersen
We analysed the cytokine profile of skin T cells by establishing 11 T-cell lines from adult patients with moderate-to-severe atopic eczema using T-cell growth factors interleukin-2 and interleukin-4. We compared T-cell lines from lesional skin of atopic dermatitis patients with those from non-atopic skin of patients with other skin diseases, observing that T-cell lines of patients with atopic derm ...
Pages: 3-7
Abstract  PDF
INVESTIGATIVE REPORT
Occurrence of Neutrophils and Activated Th1 cells in UVB-induced Erythema
Tadashi Terui, Kazuhiro Takahashi, Michitaka Funayama, Atsushi Terunuma, Maki Ozawa, Shu Sasai, Hachiro Tagami
We investigated the sequential changes in infiltrating inflammatory cells and several cytokine levels over a period of 48 h in human back skin exposed to 3 minimal erythematous doses of UVB. The measurement of blood flow, using a laser Doppler method, indicated that UVB-induced erythema reached a peak 12-24 h after irradiation. Immunohistochemically, an increase in the number of CD4+ T ...
Pages: 8-13
Abstract  PDF
INVESTIGATIVE REPORT
A Double-blind Investigation of the Potential Systemic Absorption of Isotretinoin, when Combined with Chemical Sunscreens, Following Topical Application to Patients with Widespread Acne of the Face and Trunk
William J. Cunliffe, Daniel Glass, Karen Goode, Graham I. Stables, Graham C. Boorman
This study assessed the systemic absorption of isotretinoin and its metabolites, during a 4-week application of a cream containing 0.1% isotretinoin and chemical sunscreens, compared with a 4% benzoyl peroxide cream, in patients with acne on the face and trunk. Blood was drawn at weeks 0, 1, 2, 3 and 4 and at 96 h post-treatment. Plasma levels of isotretinoin (13-cisretinoic acid) and tretinoin (a ...
Pages: 14-17
Abstract  PDF
CLINICAL REPORT
Tumour Necrosis Factor-a Promoter Polymorphism in Erythema Nodosum
Svenja Labunski, Guido Posern, Stephan Ludwig, G. Kundt, Eva-B. Bröcker, Manfred Kunz
Erythema nodosum is a common skin disease characterized by erythematous, tender subcutaneous nodules, mostly located on the lower extremities. Little is known about its pathogenesis, although a wide variety of aetiological factors (e.g. bacterial and viral infections, neoplastic diseases and drugs) have been described. Sarcoidosis, a typical granulomatous disease, often occurs in association with ...
Pages: 18-21
Abstract  PDF
CLINICAL REPORT
Comparison of Cyclosporin and UVAB Phototherapy for Intermittent One-year Treatment of Atopic Dermatitis
Håkan Granlund, Pekka Erkko, Anita Remitz, Tor Langeland, Per Helsing, Marja Nuutinen, Sakari Reitamo
Although cyclosporin is effective for the treatment of severe atopic dermatitis, phototherapy is the standard second-line treatment for this disease. An open, randomized, controlled, parallel-group study was conducted to compare the efficacy, influence on quality of life and safety of cyclosporin and UVAB phototherapy during 1 year of intermittent treatment of atopic dermatitis in adult patients. ...
Pages: 22-27
Abstract  PDF
CLINICAL REPORT
No Human Leukocyte Antigen-A, -B or -DR Association in Swedish Patients with Hidradenitis Suppurativa
Jan Lapins, Olle Olerup, Lennart Emtestam
Hidradenitis suppurativa (HS) is a cicatrizing, inflammatory and recurrent disease restricted to inverse skin, such as that of the axilla and groin of younger adults. In a previous study, using serological tissue-typing techniques, no significant increases in the human leukocyte antigen (HLA)-A and -B specificities were found in patients with HS. The aim of this study was to determine the frequenc ...
Pages: 28-30
Abstract  PDF
CLINICAL REPORT
Allergic Contact Sensitization in an Adult Danish Population: Two Cross-sectional Surveys Eight Years Apart (The Copenhagen Allergy Study)
Niels Henrik Nielsen, Allan Linneberg, Torkil Menné, Flemming Madsen, Lars Frølund, Asger Dirksen, Torben Jørgensen
In 1990 and 1998 15–41-year-old people were patch-tested in 2 cross-sectional studies of random samples of the population in the western part of Copenhagen County, Denmark. In 1990, 290 subjects and in 1998, 469 subjects were patch-tested. The participation rates were 69% and 51%, respectively. Contact sensitivity to one or more haptens was found in 15.9% and 18.6% in 1990 and 1998, respectively ...
Pages: 31-34
Abstract  PDF
CLINICAL REPORT
Recurrent Genital Herpes in a Population Attending a Clinic for Sexually Transmitted Diseases
G. B. Löwhagen, P. Tunbäck, K. Andersson, G. Johannisson
Patients with recurrent genital herpes attending a sexually transmitted disease clinic were studied and transmission of the infection was elucidated by evaluating serostatus in their partners. Of 84 patients attending for recurrent genital herpes, 94% had a herpes simplex virus type 2 (HSV-2) infection and only 6% (5 patients) a type 1 infection. The mean age of the patients was 36 years and the d ...
Pages: 35-37
Abstract  PDF
CLINICAL REPORT
Dermatoscopic Prediction of Melanoma Thickness Using Latent Trait Analysis and Likelihood Ratios
Henrik F. Lorentzen, Kaare Weismann, Frederik Grønhøj Larsen
Breslow thickness and Clark level can be used to determine surgical procedures for cutaneous malignant melanoma and patient eligibility for experimental adjuvant therapy. Efforts to predict the thickness of melanomas using dermatoscopy have focused on differences between single dermatoscopic findings. The aim of this study was to develop a method for preoperative identification of melanomas of ≥ ...
Pages: 38-41
Abstract  PDF
CLINICAL REPORT
Granulomatous Slack Skin: A Distinct Disorder or a Variant of Mycosis Fungoides?
G. Topar, B. Zelger, M. Schmuth, N. Romani, J. Thaler, N. Sepp
About 75% of cutaneous lymphomas belong to the group of T-cell lymphomas. Mycosis fungoides is the most common entity in this group. Granulomatous slack skin is a rare form of cutaneous T-cell lymphoma closely related to mycosis fungoides. We present here a patient with areas of lax skin for several years who developed a generalized erythroderma with associated immunoactivation and a deterioration ...
Pages: 42-44
Abstract  PDF
CLINICAL REPORT
Aleukemic Leukemia Cutis Presenting as Benign-appearing Exanthema
Anja Benez, Silke Metzger, Gisela Metzler, Gerhard Fierlbeck
Aleukemic leukemia cutis is a rare condition characterized by the infiltration of the skin by leukemic cells before their appearance in the peripheral blood or bone marrow. We report here a 62-year-old seemingly healthy patient who presented with disseminated erythematous maculae. A skin biopsy showed leukemia cutis of monocytic type. No involvement of bone marrow or peripheral blood was found. Th ...
Pages: 45-47
Abstract  PDF
CLINICAL REPORT
An Unusual Form of Generalized Granuloma Annulare in a Patient Insulin-dependent Diabetes Mellitus
Emel Erkek, Ayyen Karaduman, Gül Bükülmez, Nilgün zentürk, Özay Özkaya
The generalized form of granuloma annulare may be associated with systemic disorders, including diabetes mellitus. We describe here an unusual form of generalized granuloma annulare in a patient with complicated insulin-dependent diabetes mellitus. The cutaneous eruption had been present for decades as non-pruritic, persistent, violet–brown patches with raised edges. There were flexion deformiti ...
Pages: 48-50
Abstract  PDF
CLINICAL REPORT
Chronic Infection Due to Fusarium oxysporum Mimicking Lupus Vulgaris: Case Report and Review of Cutaneous Involvement in Fusariosis
M. Pereiro Jr, M. T. Abalde, A. Zulaica, J. L. Caeiro, A. Flórez, C. Peteiro, J. Toribio
A 67-year-old female presented with a 20-year-old lesion involving the right ear and preauricular area mimicking tuberculous lupus. Fusarium oxysporum infection was confirmed by biopsy studies and cultures. The biopsy specimen showed an unusually extensive dermal invasion with fungal hyphae. This is an uncommon clinical presentation for Fusarium infection in a healthy patient. When r ...
Pages: 51-53
Abstract  PDF
LETTER TO THE EDITOR
Characterization of a Novel Point Mutation (Arg432His) in X-Linked Ichthyosis
M. Valdes-Flores, A.L. Jimenez Vaca, S.H. Kofman-Alfaro, S.A. Cuevas-Covarrubias
This article does not have an abstract.
Pages: 54-55
Abstract  PDF
LETTER TO THE EDITOR
Infiltration of Activated Eosinophils in the Skin Lesions of Atopic Dermatitis
Masae Katane, Masashi Akiyama, Keiko Hatanaka, Akira Kawada, Itsuro Matsuo
This article does not have an abstract.
Pages: 56-57
Abstract  PDF
LETTER TO THE EDITOR
Acral Darier's Disease Successfully Treated with Adapalene
G. Cianchini, L. Colonna, D. Camaioni, G. Annessi, P. Puddu
This article does not have an abstract.
Pages: 57-58
Abstract  PDF
LETTER TO THE EDITOR
Famciclovir in Treatment of Acute Herpes Zoster: Results of Two Post-marketing Surveillance Studies in Germany
R. Engst, U. Schiewe, W. Höbel, K. Machka, W. Meister
This article does not have an abstract.
Pages: 59-60
Abstract  PDF
LETTER TO THE EDITOR
Oral Terbinafine for Tinea Capitis due to Microsporum Canis in Children
Geromanta Baleviciene, Olegas Ceburkovas, Danute Maciuliene
This article does not have an abstract.
Page: 61
Abstract  PDF
LETTER TO THE EDITOR
IgE-mediated Urticaria/Angioedema After Ingestion of Mussels
E. Nettis, A. Pannofino, P. Dambra, M. P. Loria, G. Di Maggio, E. Damiani, A. Ferrannini, A. Tursi
This article does not have an abstract.
Page: 62
Abstract  PDF
LETTER TO THE EDITOR
Systemic Sclerosis Following Physical Trauma
Uwe-Frithjof Haustein
This article does not have an abstract.
Page: 63
Abstract  PDF
LETTER TO THE EDITOR
Disseminated Superficial Porokeratosis with Mucosal Involvement
E. Rosón, I. García-Doval, C. de la Torre, A. Losada, T. Rodríguez, C. Ocampo, M. Cruces
This article does not have an abstract.
Pages: 64-65
Abstract  PDF
LETTER TO THE EDITOR
Mechanic's Hand: A Clinical Diagnostic Aid in Dermatomyositis
Rashmi Mittal, Vinod K. Sharma, H. R. Y. Prasad, Manoj K. Singh
This article does not have an abstract.
Pages: 65-66
Abstract  PDF
LETTER TO THE EDITOR
Lichen Myxedematosus Associated with Chronic Hepatitis C: A Case Report
M. A. Montesu, F. Cottoni, R. Sanna, D. Cerimele
This article does not have an abstract.
Pages: 67-68
Abstract  PDF
LETTER TO THE EDITOR
The Asp84Glu Variant of the MC1R Gene in Norwegian Melanoma Patients
Per Helsing, Bjørn Høyheim
This article does not have an abstract.
Pages: 68-69
Abstract  PDF
LETTER TO THE EDITOR
Erythroderma due to Dermatophyte
Ramji Gupta, Vikas Khera
This article does not have an abstract.
Page: 70
Abstract  PDF
LETTER TO THE EDITOR
Successful Sulfasalazine Treatment of Severe Chronic Idiopathic Urticaria Associated with Pressure Urticaria
Karin Hartmann, Nadja Hani, Ralf Hinrichs, Nicolas Hunzelmann, Karin Scharffetter-Kochanek
This article does not have an abstract.
Page: 71
Abstract  PDF
LETTER TO THE EDITOR
Epidermolysis Bullosa Acquisita Treated with Basiliximab, an Interleukin-2 Receptor Antibody
Michael G. Haufs, Eckart Haneke
This article does not have an abstract.
Page: 72
Abstract  PDF
LETTER TO THE EDITOR
Capnocytophaga Canimorsus Sepsis Causing Sweet's Syndrome
Bo Bang, Claus Zachariae
This article does not have an abstract.
Pages: 73-74
Abstract  PDF
LETTER TO THE EDITOR
Sarcoidosis Developing after Stopping Oral Prednisolone for Systemic Lupus Erythematosus
Kaoru Umeki, Daisuke Sawamura, Takamitsu Sugawara
This article does not have an abstract.
Page: 74
Abstract  PDF
LETTER TO THE EDITOR
Darier's Disease Seen with Cutis Verticis Gyrata
Muammer Parlak, Teoman Erdem, Ali Karakuzu, Ali Ihsan Güleç, Necmettin Akdeniz
This article does not have an abstract.
Page: 75
Abstract  PDF
LETTER TO THE EDITOR
Successful Treatment of Extensive Condyloma Acuminata of the Inguinal Area and Thigh with Topical Imiquimod Cream
Jeffrey M. Weinberg, Allison Stewart, Jerry O. Stern
This article does not have an abstract.
Pages: 76-77
Abstract  PDF
LETTER TO THE EDITOR
Unusually Large Cutaneous Metastases of Renal Cell Carcinoma
K. Peris, M. C. Fargnoli, F. Lunghi, S. Chimenti
This article does not have an abstract.
Pages: 77-78
Abstract  PDF
ANNOUNCEMENT
ANNOUNCEMENTS
This article does not have an abstract.
Page: 79
Abstract  PDF
BOOK REVIEW
BOOK REVIEWS
This article does not have an abstract.
Page: 80
Abstract  PDF