Content - Volume 83, Issue 213
The history, neurophysiology, clinical aspects and treatment
of pruritus are reviewed in this article. The different
forms of pruritus in dermatological and systemic
diseases are described, and the various aetiologies and
pathophysiology of pruritus in systemic diseases are discussed.
Lack of understanding of the neurophysiology
and pathophysiology of pruritus has hampered the development
Congenital ichthyosis comprises a rare group of usually
monogenetic diseases that present at birth as a collodion
phenotype or as variable degrees of ichthyosiform
erythroderma, with or without superficial blisters. Depending
on which gene mutation causes the disease, the
skin problems later in life may range from a severe
lamellar or bullous ichthyosis to mild or only focally
expressed hyp ...