Content

Content - Volume 89, Issue 1

Editor's choice in this issue

All articles

EDITORIAL
Editorial: Looking back on 10 years as Editor of Acta Dermato-Venereologica
Anders Vahlquist
Looking back on 10 years as Editor of Acta Dermato-Venereo­logica (ADV), I am pleased to say that the journal’s impact factor is steadily increasing and is now almost 2.0 (Fig. 1), and that our economy remains strong after 3 years without a commercial publisher. In 2008 the number of submissions increased to almost 400, the majority of papers being of high quality (approximately 50% are eventua ...
Page: 3
Abstract  HTML  PDF
IN THIS ISSUE
In this Issue. Phenotypic Complexity of Epidermolysis Bullosa: The Paradigm of the Pruriginosa Subtype
Jouni Uitto
Phenotypic Complexity of Epidermolysis Bullosa: the Paradigm of the Pruriginosa Subtype The heritable forms of epidermolysis bullosa (EB) comprise a group of mechano-bullous disorders with skin blistering as the unifying diagnostic feature (1). The clinical severity can be highly variable: in milder cases EB can present with life-long blistering tendency with no significant impact on the longevit ...
Pages: 4-5
Abstract  HTML  PDF
INVESTIGATIVE REPORT
New Glycine Substitution Mutations in Type VII Collagen Underlying Epidermolysis Bullosa Pruriginosa but the Phenotype is not Explained by a Common Polymorphism in the Matrix Metalloproteinase-1 Gene Promoter
Noor Almaani, Lu Liu, Naomi Harrison, Akio Tanaka, Joey E. Lai-Cheong, Jemima E. Mellerio and John A. McGrath
Epidermolysis bullosa (EB) pruriginosa is an unusual variant of dystrophic EB in which intense itching can lead to striking skin changes resembling acquired skin disorders such as nodular prurigo or hypertrophic lichen planus. The molecular pathology involves mutations in the COL7A1 gene, but the nature of the mutations is similar to those seen in other non-pruritic forms of dystrophic EB. The mec ...
Pages: 6-11
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Expression of Retinoid-regulated Genes in Lamellar Ichthyosis vs. Healthy Control Epidermis: Changes after Oral Treatment with Liarozole
Elizabeth Pavez Loriè, Agneta Gånemo, Marcel Borgers, Luc Wouters, Stan Blockhuys, Lieve van de Plassche, Hans Törmä, Anders Vahlquist
Lamellar ichthyosis is a keratinization disorder caused by TGM1, Ichthyin and several other gene mutations. A new treatment option is liarozole, which blocks the cytochrome P450 (CYP26)-mediated catabolism of endogenous all-trans retinoic acid. This study focuses on the expression of retinoid-related genes in ichthyotic epidermis before and after treatment with oral liarozole. We first compared th ...
Pages: 12-20
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Functional Characteristics of the Skin Surface of Children Approaching Puberty: Age and Seasonal Influences
Nobuko Akutsu, Motoki Ooguri, Tomoko Onodera, Yusuke Kobayashi, Masako Katsuyama, Naomi Kunizawa, Tetsuji Hirao, Junichi Hosoi, Yuji Masuda, Seiichi Yoshida, Motoji Takahashi, Toru Tsuchiya, Hachiro Tagami
The aim of this study was to determine differences in the functional properties of the stratum corneum of children and adults, focusing on the influence of approaching puberty. Biophysical measurements were made of the stratum corneum of 32 healthy Japanese children aged 10-14 years and their mothers in summer and the following winter. The children showed significantly lower skin surface hydration ...
Pages: 21-27
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Does Vitamin D Intake During Infancy Promote the Development of Atopic Allergy?
Ove Bäck, Hans K:son Blomquist, Olle Hernell and Berndt Stenberg
The active metabolite of vitamin D, 1,25-(OH)2D3, has immunomodulatory properties in addition to its more established action on bone and calcium metabolism. Recently vitamin D has been proposed as one of several environmental factors responsible for the increase in atopic diseases during the last decades. The objective of this study was to determine whether the estimated dose of dietary vitamin D3 ...
Pages: 28-32
Abstract  HTML  PDF
Impact of Adult Atopic Dermatitis on Topical Drug Penetration: Assessment by Cutaneous Microdialysis and Tape Stripping
Patricia Garcia Ortiz, Steen H. Hansen, Vinod P. Shah, Torkil Menné, Eva Benfeldt
Appropriate methodologies for the determination of drug penetration in diseased skin have not yet been established. The aim of this study was to determine the cutaneous penetration of a metronidazole cream formulation in atopic dermatitis, employing dermal microdialysis and tape strip sampling techniques. Non-invasive measuring methods were used for the quantification of the severity of the dermat ...
Pages: 33-38
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Itch and Mental Distress: A Cross-Sectional Study among Late Adolescents
Jon Anders Halvorsen, Florence Dalgard, Magne Thoresen, Espen Bjertness and Lars Lien
Itch is known to be associated with psychological factors in adults, but has not been explored among adolescents. A cross-sectional, questionnaire-based population study involving adolescents born mostly in 1986 was carried out in 2004. A total of 4744 individuals were invited and the participation rate was 80%. The Hopkins Symptom Checklist-10 was used to measure mental distress. The prevalence o ...
Pages: 39-44
Abstract  HTML  PDF
CLINICAL REPORT
Treatment of Chronic Pruritus with the Selective Serotonin Re-uptake Inhibitors Paroxetine and Fluvoxamine: Results of an Open-labelled, Two-arm Proof-of-concept Study
Sonja Ständer, Barbara Böckenholt, Funda Schürmeyer-Horst, Carsten Weishaupt, Gereon Heuft, Thomas A. Luger and Gudrun Schneider
Chronic pruritus is difficult to treat and requires the evaluation of new therapeutic modalities. We initiated an open-labelled, two-arm prospective, proof-of-concept study applying two selective serotonin re-uptake inhibitors on a long-term basis. Paroxetine and fluvoxamine were tested in a total of 72 pruritic patients (27 men, 45 women, age range 28–88 years, mean age 59.2 years). The reducti ...
Pages: 45-51
Abstract  HTML  PDF
CLINICAL REPORT
Exogenous Histamine Aggravates Eczema in a Subgroup of Patients with Atopic Dermatitis
Margitta Worm, Eva-Maria Fiedler, Sabine Dölle, Tania Schink, Wolfgang Hemmer, Reinhart Jarisch, Torsten Zuberbier
Food and beverages may contain high amounts of histamine and thus may cause symptoms after ingestion. The aim of this study was to investigate the role of ingested histamine in atopic dermatitis. Patients with atopic dermatitis had to maintain a histamine-free diet for one week. Consecutively, double-blind, placebo-controlled provocations were performed with histamine-hydrochloride and placebo. Th ...
Pages: 52-56
Abstract  HTML  PDF
CLINICAL REPORT
Effectiveness of a Multidisciplinary Itch-coping Training Programme in Adults with Atopic Dermatitis
Andrea W.M. Evers, Piet Duller, Elke M.G.J. de Jong, Marisol E. Otero, Christianne M. Verhaak, Pieter G.M. van der Valk, Peter C.M. van de Kerkhof, Floris W. Kraaimaat
The short- and longer-term effectiveness of a brief, multidisciplinary itch-coping group training scheme in adults with atopic dermatitis was evaluated. Clinical severity scores (Eczema Area and Severity Index) and validated self-report measures were obtained in a waiting-list control condition (n=30) and a treatment condition (n=61) at pre- and post-treatment and in the treatment condition at 3- ...
Pages: 57-63
Abstract  HTML  PDF
CLINICAL REPORT
Skin Problems in Ostomy Patients: A Case-control Study of Risk Factors
Hanne Nybæk, Dorte Bang Knudsen, Troels Nørgaard Laursen, Tonny Karlsmark and Gregor B. E. Jemec
Skin complications are frequent in ostomy patients and a number of risk factors have been suggested. The data on risk factors have, however, been documented mainly in single-centre studies and the actual importance of the suggested risk factors should therefore be verified in a group of ostomy patients broadly selected from the gene­ral population. All patients with permanent ostomies living in R ...
Pages: 64-67
Abstract  HTML  PDF
CLINICAL REPORT
Sjögren-Larsson Syndrome: A Study of Clinical Symptoms and Dermatological Treatment in 34 Swedish Patients
Agneta Gånemo, Sten Jagell and Anders Vahlquist
Sjögren-Larsson syndrome (SLS) is a recessively inherited disease with congenital ichthyosis, spastic diplegia or tetraplegia and mental retardation, caused by a deficiency of fatty aldehyde dehydrogenase. The aim of this study was to examine all 34 Swedish patients with SLS, emphasizing skin symptoms, dermatological treatment, and neurological symptoms (evaluated in some cases for more than 25 y ...
Pages: 68-73
Abstract  HTML  PDF
CLINICAL REPORT
Primary Cutaneous CD30+ Anaplastic Large Cell Lymphoma in a Heart Transplant Patient: Case Report and Literature Review
Anna Belloni-Fortina, Maria Cristina Montesco, Stefano Piaserico, Matteo Bordignon, Francesco Tona, Giuseppe Feltrin, Mauro Alaibac
Solid organ transplant recipients are at risk of developing a wide range of viral-associated malignancies, including skin tumours and lymphoproliferative disorders. The risk of a post-transplant lymphoproliferative disorder is 28-49 times the risk of a lymphoproliferative disorder in the normal population. Most cases are of B-cell phenotype and are associated with Epstein-Barr virus infection. Pos ...
Pages: 74-77
Abstract  HTML  PDF
LETTER TO THE EDITOR
Gender Differences in Topical Treatment of Allergic Contact Dermatitis
Eline Noiesen, Martin D. Munk, Kristian Larsen, Marianne Høyen, Tove Agner
Abstract is missing (Letter)
Pages: 79-81
Abstract  HTML  PDF
LETTER TO THE EDITOR
Etanercept for the Treatment of Hidradenitis Suppurativa
Eleni Sotiriou, Zoe Apalla and Dimitrios Ioannidos
Abstract is missing (Letter)
Pages: 82-83
Abstract  HTML  PDF
LETTER TO THE EDITOR
Two Cases of Confluent and Reticulated Papillomatosis with an Unusual Location
Deborah Lee, Kyung-Jong Cho, Soon-Kwon Hong, Jong-Keun Seo, Seon-Wook Hwang and Ho-Suk Sung
Abstract is missing (Letter)
Pages: 84-85
Abstract  HTML  PDF
LETTER TO THE EDITOR
Multiple Morphea-like lesions Associated with Chronic Graft-versus-host Disease after Cord Blood Transplantation
Yoshio Kawakami, Mikio Ohtsuka, Atsushi Kikuta and Toshiyuki Yamamato
Abstract is missing (Letter)
Pages: 86-87
Abstract  HTML  PDF
LETTER TO THE EDITOR
Congenital Melanocytic Naevus with Atypical Pigment Network on Dermoscopy
Takahiro Kiyohara, Kenya Kawami, Yoshiaki Imamura, Masaru Tanaka, Minoru Takata, Masanobu Kumakiri
Abstract is missing (Letter)
Pages: 88-89
Abstract  HTML  PDF
LETTER TO THE EDITOR
Opioid Antagonist for Pruritus of Cholestasis Unmasking Bony Metastases
Ann A. Lonsdale-Eccles and Andrew J. Carmichael
Abstract is missing (Letter)
Page: 90
Abstract  HTML  PDF
LETTER TO THE EDITOR
Widespread Mycobacterium marinum Infection
Susanne Fabricius, Hanne Fogh, Gregor Jemec, Bo Baslund and Tove Agner
Abstract is missing (Letter)
Pages: 91-92
Abstract  HTML  PDF
LETTER TO THE EDITOR
Septic Shock after Treatment of Pyoderma Gangrenosum with Infliximab
Florian Wölbing, Gerhard Fierlbeck, Wolfram Hötzenecker, Martin Schaller and Martin Röcken
Abstract is missing (Letter)
Pages: 93-94
Abstract  HTML  PDF
LETTER TO THE EDITOR
Scleroderma-like Reaction Restricted to the Red Parts of a Tattoo
Nicolas Kluger, Pascale Mathelier-Fusade­ and Philippe Moguelet
Abstract is missing (Letter)
Pages: 95-96
Abstract  HTML  PDF
LETTER TO THE EDITOR
Borrelia Infection and Pityriasis Rosea
Giuseppe Stinco, Maurizio Ruscio, Davide Proscia, Fabio Piccirillo
Abstract is missing (Letter)
Pages: 97-98
Abstract  HTML  PDF
LETTER TO THE EDITOR
Novel Treatment for Cheilitis Glandularis
Hendrik Jorn Bovenschen
Abstract is missing (Letter)
Pages: 99-100
Abstract  HTML  PDF
LETTER TO THE EDITOR
Successful Treatment of Mucous Membrane Pemphigoid with the Anti-CD-20 Antibody Rituximab
Tamara Schumann, Enno Schmidt, Nina Booken, Sergij Goerdt, Matthias Goebeler
Abstract is missing (Letter)
Pages: 101-102
Abstract  HTML  PDF
LETTER TO THE EDITOR
Cutaneous Granulomatous Infection Caused by Scopulariopsis brevicaulis
Ching-Ying Wu, Chih-Hung Lee, Hsing-Lin Lin, Chieh-Shan Wu
Abstract is missing (Letter)
Pages: 103-104
Abstract  HTML  PDF
LETTER TO THE EDITOR
Pyoderma Gangrenosum with Myelodysplastic Syndrome Treated with Analogous Bone Marrow Transplantation
Kazuhoshi Yamanaka, Shuichi Kuniyuki, Naoki Maekawa, Yuki Yoshida, Hirohumi Teshima
Abstract is missing (Letter)
Pages: 105-106
Abstract  HTML  PDF
LETTER TO THE EDITOR
Pustular Bacterid Associated with Ankylosing Spondylitis
Ting Xiao, Hong-Guang Lu, Jian Wu, Chun-Di He, Hong-Duo Chen
Abstract is missing (Letter)
Pages: 107-108
Abstract  HTML  PDF
LETTER TO THE EDITOR
Is Pruritus in Depression a Rare Phenomenon?
Przemysław Pacan, Magdalena Grzesiak, Adam Reich, Jacek C. Szepietowski
Abstract is missing (Letter)
Pages: 109-110
Abstract  HTML  PDF