Content

Content - Volume 89, Issue 2

Editor's choice in this issue

All articles

INVESTIGATIVE REPORT
Lack of Association between Neuropeptide S Receptor 1 Gene (NPSR1) and Eczema in Five European Populations
Elisabeth Ekelund, Maria Bradley, Stephan Weidinger, Dragan L. Jovanovic, Catharina Johansson, Cecilia M. Lindgren, Antonia Todorova, Thilo Jakob, Thomas Illig, Erika von Mutius, Charlotte Braun-Fahrländer, Gert Doekes, Josef Riedler, Annika Scheynius, Göran Pershagen, Ingrid Kockum and Juha Kere
Eczema is often associated with development of allergic asthma. The Neuropeptide S Receptor 1 (NPSR1) gene has previously been associated with asthma and elevated serum IgE levels. The aim of this study was to investigate a potential association between the NPSR1 gene and eczema in patients and healthy individuals from five different populations in Western Europe, in total 6275 individuals. Seven ...
Pages: 115-121
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INVESTIGATIVE REPORT
Prevalence of Atopic Dermatitis in Italian Schoolchildren: Factors Affecting its Variation
Luigi Naldi, Fabio Parazzini, Silvano Gallus and GISED study centres
The frequency of atopic dermatitis in Italian children and its relationship with selected variables were analysed in a large survey of skin health conducted in Italy. In 1997 we conducted a survey on schoolchildren aged 12–17 years from 13 areas of northern, central and southern Italy. For the present analyses, 3179 Caucasian children (1618 males, 1561 females) were considered. A diagnosis of ...
Pages: 122-125
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INVESTIGATIVE REPORT
Effect of Pentane-1,5-diol and Propane-1,2-diol on Percutaneous Absorption of Terbinafine
Hanne Evenbratt and Jan Faergemann
The aim of this study was to compare pentane-1,5-diol and propane-1,2-diol used as absorption enhancers for cutaneously administered terbinafine. Fresh human skin samples were placed in a continuous flow diffusion cell with a gel containing terbinafine on top of the skin. Receptor fluid samples were analysed using high - performance liquid chromatography. The quantity of gel remaining on the ski ...
Pages: 126-129
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INVESTIGATIVE REPORT
Measurement of Nickel, Cobalt and Chromium in Toy Make-up by Atomic Absorption Spectroscopy
Monica Corazza, Federica Baldo, Antonella Pagnoni, Roberta Miscioscia and Annarosa Virgili
Cosmetics should not contain more than 5 ppm of nickel, chromium or cobalt and, in order to minimize the risk of sensitization in very sensitive subjects, the target amount should be as low as 1 ppm. However, there are no published reports on the presence of these metals in toy make-up. This study analysed 52 toy make-ups using atomic absorption spectroscopy. More than 5 ppm of nickel was present ...
Pages: 130-133
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INVESTIGATIVE REPORT
Topical Application of Imiquimod Induces Alterations in Peripheral Blood Lymphocytes in Healthy Individuals*
Efi Pasmatzi, Antigoni Chaidaroglou, Theophilos Sakkis, Alexandra Monastirli, Sophia Georgiou, Alexandros Sagriotis, George Badavanis, Eleftheria Vryzaki, Panagiota Matsouka, Dimitrios Degiannis and Dionysios Tsambaos
The aim of this study was to determine whether imiquimod, a Toll-like receptor-7/8 agonist, in addition to its well-known topical action on the cutaneous immune response, might also induce alterations in the peripheral blood lymphocytes. A 62.5 mg quantity of imiquimod (5% cream) was applied topically under occlusion once daily every second day for 3 weeks to the skin of 10 healthy volunteers, age ...
Pages: 134-139
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INVESTIGATIVE REPORT
Immunological and Clinical Effects of Alphacalcidol in Patients with Psoriatic Arthropathy: Results of an Open, Follow-up Pilot Study
János Gaál, Gabriella Lakos, Péter Szodoray, Judit Kiss, Irén Horváth, Edit Horkay, Georgina Nagy and Andrea Szegedi
The aim of this study was to describe the effect of systemic alphacalcidol (1 OH vitamin D3) treatment on clinical and immunological parameters in patients with psoriatic arthropathy. Among the 19 patients investigated, 10 were treated with 0.25 µg oral alphacalcidol twice daily for 6 months, while 9 other patients served as controls. In the peripheral blood of the treated group but not in the co ...
Pages: 140-144
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INVESTIGATIVE REPORT
Cold Water and Pauses in Illumination Reduces Pain During Photodynamic Therapy: A Randomized Clinical Study
Stine Regin Wiegell, Merete Hædersdal, Hans Christian Wulf
Pain is the main acute adverse event during photodynamic therapy of skin lesions. The objective of this randomized study was to evaluate the pain-relieving effect of pauses and cooling during illumination. Twenty-four patients with actinic keratoses were treated with photodynamic therapy in two symmetrical areas and cooled with either cold-water-spray or cold-water-pack (CoolPack). Treatment areas ...
Pages: 145-149
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CLINICAL REPORT
Photodynamic Therapy Following Carbon Dioxide Laser Enhances Efficacy in the Treatment of Extramammary Paget's Disease
Toshimitsu Fukui, Daisuke Watanabe, Yasuhiko Tamada and Yoshinari Matsumoto
Surgical resection is the first-choice therapy for extramammary Paget's disease, but extensive resection is highly invasive and non-surgical treatments are sometimes preferred. Although photodynamic therapy (PDT) has been used for extramammary Paget's disease for some time, recurrence and residual tumour cells are common. In the present study, five patients with extramammary Paget's disease with a ...
Pages: 150-154
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CLINICAL REPORT
Therapeutic Effectiveness of Various Treatments for Eosinophilic Pustular Folliculitis
Shoko Fukamachi, Kenji Kabashima, Kazunari Sugita, Miwa Kobayashi and Yoshiki Tokura
Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pustular folliculitis. Twenty patients with eosinophilic pustular folliculitis seen ...
Pages: 155-159
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CLINICAL REPORT
Eccrine Poroma: A Clinical-Dermoscopic Study of Seven Cases
Angela Ferrari, Pierluigi Buccini, Vitaliano Silipo, Paola De Simone, Giustino Mariani, Samantha Marenda, Johanna H. Hagman, Ada Amantea, Chiara Panetta and Caterina Catricalà
Eccrine poroma can mimic benign and malignant melanocytic and non-melanocytic lesions. To date, little is known about the dermoscopic features of this condition. Seven histopathologically proven cases of eccrine poroma were examined using dermoscopy by three independent dermatologists. Both glomerular and hairpin vessels were observed in 71% of cases, whereas linear irregular vessels were observed ...
Pages: 160-164
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CLINICAL REPORT
Delusional Parasitosis: Lessons Learnt
Kashif Ahmad and Bart Ramsay
Delusional parasitosis manifests in the patient's firm belief that they have skin symptoms due to an infestation with insects. Patients often refuse to seek psychiatric care. This study reassessed patients with delusional parasitosis in order to review and learn from them, which is important due to the significant morbidity of this condition and the therapeutic difficulties it presents to the de ...
Pages: 165-168
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CLINICAL REPORT
Multiple Epidermolytic Acanthomas Must Not be Confused with Genital Human Papillomavirus Infection
Tarun Kukreja and Aleksandar Krunic
We describe two patients with multiple epidermolytic acanthomas on the scrotum initially referred to our clinic as genital warts. Both patients presented with multiple tan-colored warty papules scattered on the scrotal skin. Biopsy revealed hyperkeratosis, hypergranulosis, and clear cell changes consistent with epidermolytic acan thoma. Human papillomavirus was not detected and the lesions clear ...
Pages: 169-174
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CLINICAL REPORT
T-cell Large Granular Lymphocytic Leukaemia with an Uncommon Clinical and Immunological Phenotype
Maurice A. M. van Steensel, Michel van Gelder, Ariënne M. W. van Marion, Bernd Kremer and Jorge Frank
A 39-year-old man presented with a rapidly growing unilateral painless nodule on the right cheek. Histopathological examination and peripheral blood analysis both showed a population of T-cell large granular lymphocytes, which were CD1+, CD2+, CD5+, CD7+ and CD16+, with expression of cutaneous lymphocyte-associated antigen. Further laboratory examination revealed severe neutropaenia, relative lymp ...
Pages: 172-174
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CLINICAL REPORT
Myeloid Sarcoma Developing in Pre-existing Pyoderma Gangrenosum
Ida Bruun Kristensen, Hanne Møller, Mette Wanscher Kjærskov, Knud Yderstræde, Michael Boe Møller and Olav J. Bergmann
We report here a case of pyoderma gangrenosum in a patient with myelodysplastic syndrome developing into myeloid sarcoma as a sign of transformation to acute leukaemia. The patient was treated successfully with intensive chemotherapy and achieved complete remission, and her otherwise expanding ulcers started to heal. This is the first reported case of secondary blastic infiltration in pyoderma gan ...
Pages: 175-177
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LETTER TO THE EDITOR
Psoriasiform Acral Dermatitis: Long-term Follow-up of 10 Cases
Annalisa Patrizi, Matelda Medri and Iria Neri
This article does not have an abstract.
Pages: 179-180
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LETTER TO THE EDITOR
Lymphangioma Circumscriptum of the Vulva: A Case Report
Müzeyyen Gönül, Seray Külcü Çakmak, Seçil Soylu, Arzu Kılıç, Hülya Gündüz, Ülker Gül and Tuba Ünal
This article does not have an abstract.
Pages: 180-181
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LETTER TO THE EDITOR
Homeopathic Treatment of Children with Atopic Eczema: A Prospective Observational Study with Two Years Follow-up
Claudia M. Witt, Rainer Lüdtke, Stefan N. Willich
This article does not have an abstract.
Pages: 182-183
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LETTER TO THE EDITOR
Merkel Cell Carcinoma Associated with In situ and Invasive Squamous Cell Carcinoma
Begoña Vieites, José M. Suárez-Peñaranda, Victor Delgado, Hugo Vázquez-Veiga, Juan Varela, Jerónimo Forteza
This article does not have an abstract.
Pages: 184-186
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LETTER TO THE EDITOR
Pyoderma Vegetans: A Case for Discussion
Esra Adişen, Fulya Tezel and Mehmet Ali Gürer
This article does not have an abstract.
Pages: 186-188
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LETTER TO THE EDITOR
Bullous Pilomatricoma: A Particular and Rare Dermal Bullous Disorder
Vincenzo de Giorgi, Barbara Alfaioli, Daniela Massi, Alessia Gori, Serena Sestini, Federica Papi, Marta Grazzini and Torello Lotti
This article does not have an abstract.
Pages: 189-190
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LETTER TO THE EDITOR
Vulvar Basal Cell Carcinoma with Clitoral Involvement
Husnu Celik, Bilgin Gurates, Adem Yavuz, Zeynep Dogan, Bengu Cobanoglu and Yunus Saral
This article does not have an abstract.
Pages: 191-192
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LETTER TO THE EDITOR
Sudden Eruption of Pigmentary Spots on Vitiligo Universalis Patient: Possible Misdiagnosis
Eun Chun Han, Kyu-yeop Lee, Jung-U Shin, Yoon Kee Park, Mi Ryung Roh
This article does not have an abstract.
Pages: 192-193
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LETTER TO THE EDITOR
Acquired Haemophilia Mimicking Dermatitis Artefacta
Corinna Simone Brod, Claus Garbe, Jan Schleicher, Martin Röcken and Melany Schilling
This article does not have an abstract.
Pages: 194-195
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LETTER TO THE EDITOR
Compression Bandage as Treatment for Ulcers Induced by Intramuscular Self-injection of Paraffin Oil
Line Iversen, Asja Lemcke, Mikael Bitsch and Tonny Karlsmark
This article does not have an abstract.
Pages: 196-197
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LETTER TO THE EDITOR
Labial Agglutination in a Prepubertal Girl: Effect of Topical Oestrogen
Marie Hjerrild Velander, Dorthe Bisgaard Mikkelsen and Anette Bygum
This article does not have an abstract.
Pages: 198-199
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LETTER TO THE EDITOR
Eosinophilic Pustular Folliculitis Occurring after Bone Marrow Transplantation in a Child with Aplastic Anaemia
Eisaku Ogawa, Ryuhei Okuyama, Hidetaka Niizuma, Hachiro Tagami, Shigeru Tsuchiya and Setsuya Aiba
This article does not have an abstract.
Pages: 200-201
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LETTER TO THE EDITOR
HLA-B*51 in Patients with Recurrent Aphthous Stomatitis
Mustafa Özdemir, Hasan Acar, Fatma Deniz, Emrah Tümer, Burhan Engin and Özgür Balasar
This article does not have an abstract.
Pages: 202-203
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LETTER TO THE EDITOR
Tinea Capitis Caused by Trichophyton equinum
Jochen Brasch, Birgit Lögering and Yvonne Gräser
This article does not have an abstract.
Pages: 204-205
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LETTER TO THE EDITOR
Borderline Lepromatous Leprosy Presenting as a Single Cutaneous Plaque
Hideki Maejima, Norihisa Ishii, Ryouichi Aki, Kensei Katsuoka and Shuichi Obata
This article does not have an abstract.
Pages: 206-207
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LETTER TO THE EDITOR
Epithelioid Sarcoma-like Haemangioendothelioma: A Case Report
Akiko Watabe, Ryuhei Okuyama, Akira Hashimoto, Masami Hosaka, Masahito Hatori, Yoshiyuki Kariya, Mika Watanabe, Hiroshi Hashimoto, Hachiro Tagami and Setsuya Aiba
This article does not have an abstract.
Pages: 208-209
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LETTER TO THE EDITOR
Erythrosis Pigmentosa Mediofacialis: Familial Occurrence
H. Jorn Bovenschen and Marieke M. B. Seyger
This article does not have an abstract.
Pages: 210-211
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LETTER TO THE EDITOR
Isolated Extragenital Bowenoid Papulosis of the Toe-webs
Sang Ho Oh, Ju Hee Lee, Kyu-yeop Lee and Kwang Hoon Lee
This article does not have an abstract.
Pages: 212-213
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LETTER TO THE EDITOR
Severe Post-herpetic Neuralgia Successfully Treated with Botulinum Toxin A: Three Case Reports
Eleni Sotiriou, Zoe Apalla, Despina Panagiotidou and Demetris Ioannidis
This article does not have an abstract.
Pages: 214-215
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LETTER TO THE EDITOR
Penile Ulceration During Pegylated Doxorubicin Chemotherapy of Classical Kaposi's Sarcoma
Serafinella P. Cannavò, Francesco Borgia, Antonino Scimone and Biagio Guarneri
This article does not have an abstract.
Pages: 216-217
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LETTER TO THE EDITOR
Lymphangioleiomyomatosis in a Patient with Tuberous Sclerosis and Dysregulated Diabetes Mellitus
Carsten Sauer Mikkelsen, Dorthe Bisgaard Mikkelsen, Helle Dall Madsen, Poul Erik Andersen, Pernille Ravn and Anette Bygum
This article does not have an abstract.
Pages: 218-219
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LETTER TO THE EDITOR
Secondary Anetoderma Overlying Schwannoma
Woo Jin Lee, Ji Hye Yang, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Kee Chan Moon and Jai Kyoung Koh
This article does not have an abstract.
Pages: 219-220
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LETTER TO THE EDITOR
Tortuous Innominate Artery Simulating a Supraclavicular Subcutaneous Tumour
Tohru Tanigawa, Atsushi Shinohara, Takashi Sato, Jun-ichi Yamashita, Shigeru Inafuku
This article does not have an abstract.
Pages: 221-222
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