Content » Vol 48, Issue 9

Original report

Impaired cardiorespiratory fitness after aneurysmal subarachnoid hemorrhage

Wouter J. Harmsen, Gerard M. Ribbers, Bart Zegers, Emiel M. Sneekes, Majanka H. Heijenbrok-Kal, Ladbon Khajeh, Fop van Kooten, Sebastiaan J.C.M.M Neggers, Rita J.G. van den Berg-Emons
Rehabilitation Medicine, Erasmus MC, 3015 CE Rotterdam, The Netherlands. E-mail: w.harmsen@erasmusmc.nl
DOI: 10.2340/16501977-2127

Abstract

Objective: To assess cardiorespiratory fitness in patients following an aneurysmal subarachnoid haemorrhage and to explore this in fatigued and non-fatigued patients.
Design: Cross-sectional case-control study.
Subjects/patients: A total of 28 patients, 6 months post aneurysmal subarachnoid haemorrhage, and 28 sex- and age-matched controls.
Methods: Cardiorespiratory responses to a progressive cardiopulmonary exercise test on a cycle ergometer were obtained using indirect calorimetry. Fatigue was assessed using the Fatigue Severity Scale.
Results: Mean peak oxygen uptake (V̇O2peak) was significantly lower in patients (22.0 (standard deviation (SD) 6.2) ml/kg/min) than in controls (69% of controls, p < 0.001). All other cardiorespiratory fitness parameters were also lower, with peak levels ranging from 62% to 77% of matched controls. Mean V̇O2peak was 19.4 (SD 4.1) ml/kg/min in fatigued patients (63% of matched controls, p < 0.001) and 23.9 (SD 6.9) ml/kg/min in non-fatigued patients (74% of matched controls, p = 0.002).
Conclusion: Cardiorespiratory fitness is impaired after aneurysmal subarachnoid haemorrhage, both in fatigued and non-fatigued patients. This finding may have implications for treatment.

Lay Abstract

Comments

Do you want to comment on this paper? The comments will show up here and if appropriate the comments will also separately be forwarded to the authors. You need to login/create an account to comment on articles. Click here to login/create an account.
Advertisement