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Acta Dermato-Venereologica
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From current issue: 4 (95)

Increased Expression of the Wnt Signalling Inhibitor Dkk-1 in Non-lesional Skin and Peripheral Blood Mononuclear Cells of Patients with Plaque PsoriasisInvestigative Report
Increased Expression of the Wnt Signalling Inhibitor Dkk-1 in Non-lesional Skin and Peripheral Blood Mononuclear Cells of Patients with Plaque Psoriasis
Oliver Seifert, Jan Söderman, Marita Skarstedt, Olaf Dienus, Andreas Matussek

Psoriasis is a common inflammatory skin disease characterised by abnormal keratinocyte proliferation, increased dermal angiogenesis and systemic inflammation. The cell signalling cascades provoked by Wnt proteins and their inhibitors, such as Dickkopf-1, play crucial roles to maintain homeostasis of a variety of tissues, including skin, and are also involved in angiogenesis and innate immunity. Th ...


Decrease in Chymase Activity is Associated with Increase in IL-6 Expression in Mast Cells in Atopic DermatitisInvestigative Report
Decrease in Chymase Activity is Associated with Increase in IL-6 Expression in Mast Cells in Atopic Dermatitis
Tiina Ilves, Ilkka T. Harvima

Mast cell chymase and interleukin (IL)-6 can be involved in atopic dermatitis and chymase can degrade IL-6. Our aim was therefore to study the expression of mast cell chymase and IL-6 in atopic skin using enzyme- and immunohistochemistry and to analyse their interaction in vitro. Chymase activity was significantly reduced in mast cells in skin lesions whereas the percentage of IL-6+ mast cells was ...


Linear IgA Bullous Dermatosis: A Retrospective Study of 23 Patients in DenmarkClinical Report
Linear IgA Bullous Dermatosis: A Retrospective Study of 23 Patients in Denmark
Kristina Lings, Anette Bygum

Linear IgA bullous dermatosis (LAD) is an autoimmune, chronic bullous disease affecting primarily young children and adults. Studies on LAD are relatively sparse and from Scandinavia we could only find a few case reports. Therefore we decided to conduct a retrospective investigation of patients seen at our department since 1972. A total of 23 patients were identified; 7 children (F:M ratio 0.75) ...


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Blastic Plasmacytoid Dendritic Cell Neoplasm in a 7-year-old Girl with a Solitary Skin Lesion Mimicking Traumatic Purpura
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Epidermal Thickness at Different Body Sites: Relationship to Age, Gender, Pigmentation, Blood Content, Skin Type and Smoking Habits
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Allergenic Oxidation Products
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Vogt-Koyanagi-Harada Syndrome Associated with Psoriasis and Autoimmune Thyroid Disease
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New release of full articles

Special Report - 2015-04-15
Intralesional 5-Fluorouracil in Keloid Treatment: A Systematic Review
Eveline Bijlard, Sanne Steltenpool, Frank B. Niessen

Clinical Report - 2015-04-14
Sentinel Node Status and Immunosuppression: Recurrence Factors in Localized Merkel Cell Carcinoma
Thomas Jouary, Emeline Kubica, Stéphane Dalle, Cecile Pages, Anne-Benedicte Duval-Modeste, Bernard Guillot, Sandrine Mansard, Philippe Saiag, François Aubin, Christophe Bedane, Sophie Dalac, Anne Dompmartin, Florence Granel-Brocard, Catherine Lok, Pierre-Emmanuel Stoebner, Jean-Philippe Lacour, Marie-Therese Leccia, Abou Diallo, Khaled Ezzedine, Christina Mateus

Investigative Report - 2015-04-14
A Human Surrogate Model of Itch Utilizing the TRPA1 Agonist Trans-cinnamaldehyde
Chris R. Højland, Hjalte H. Andersen, Jeppe N. Poulsen, Lars Arendt-Nielsen, Parisa Gazerani

Short communication - 2015-04-14
Five-day Azithromycin Treatment Regimen For Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis
Magnus Unemo, Kim M.A. Endre, Harald Moi

Investigative Report - 2015-04-13
A Case of Subepidermal Blistering Disease with Autoantibodies to Multiple Laminin Subunits who Developed Later Autoantibodies to Alpha-5 Chain of Type IV Collagen Associated with Membranous Glomerulonephropathy
Hirohiko Sueki, Yoshinori Sato, Shinpei Ohtoshi, Tokio Nakada, Ashio Yoshimura, Chiharu Tateishi, Dorin-Bogdan Borza, William Fader, Reza F. Ghohestani, Yoshiaki Hirako, Hiroshi Koga, Norito Ishii, Atsunari Tsuchisaka, Hua Qian, Xiaoguang Li, Takashi Hashimoto

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ISI Impact Factor 2013: 4.244

No. 5 among the world's dermatological journals – highest in Europe!

An international peer-reviewed journal for clinical and experimental research in the field of dermatology and venereology.

Published by a Non-Profit Organization

Topics: Atopic dermatitis and contact allergy, facial dermatoses and adnexal disorders, new treatments, psoriasis and genodermatoses, psychodermatology, sexually transmitted diseases, skin biology and inflammation, skin cancer and pigmentation, skin immunology and lymphoma, urticaria and itch, wound healing and tissue repair


The official Journal of:
International Forum for the Study of Itch
European Society for Dermatology and Psychiatry

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