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These articles have been accepted for publication in Acta Dermato-Venereologica and are currently being edited and typeset. Readers should note that articles published below have been fully refereed, but have not been through the copy-editing and proof correction process. Only Abstract is possible to read. When this process is finalized the complete paper will be able to find.
SHORT COMMUNICATION
Blau Syndrome: Report of a Rare Entity with Congenital Ostium Secundum Atrial Septal Defect in a 7-year-old Chinese Girl
Xian-hong Yang, Lin Lin, Jian-fang Sun, Yi-qun Jiang
Abstract is missing (Short communication)
Abstract
REVIEW
A Review of Cutaneous Microdialysis of Inflammatory Dermatoses
Helen Rea, Brian Kirby
Microdialysis is a minimally invasive technique to study metabolic, biochemical, and pharmacological events in tissue. Factors that influence microdialyslate collection include molecular weight cutoff of the membrane, perfusion rate, perfusate viscosity, duration of collection, depth of the catheter, length of the tubing and adsorption of hydrophobic molecules to the membrane. To standardize these ...
Abstract
CLINICAL REPORT
Clinical Efficacy of Oligofructans from Ophiopogon japonicus in Reducing Atopic Dermatitis Flare-ups in Caucasian Patients
Carine Mainzer, Maud Le Guillou, Raoul Vyumvuhore, Bernard Chadoutaud, Sylvie Bordes, Brigitte Closs
Atopic dermatitis is a chronic relapsing inflammatory skin disease affecting 15–20% children and 2–10% adults worldwide. Topical treatments include corticosteroids and calcineurin inhibitors, despite frequently observed adverse events such as skin atrophy, itching and burning sensations. Good alternatives that can prolong disease relief in between flare-ups are therefore needed. We conducted a ...
Abstract
SHORT COMMUNICATION
Dowling-Degos Disease and Hidradenitis suppurativa. Epidemiological and Clinical Study of 15 patients and Review of the Literature
Eugenia Agut-Busquet, Iris González-Villanueva, Jorge Romani de Gabriel , Jose Carlos Pascual, Miquel Ribera Pibernat, Jesús Luelmo
Abstract is missing (Short communication)
Abstract
SHORT COMMUNICATION
Satisfaction with Information Provision and Health-related Quality of Life in Basal and Squamous Cell Carcinoma Patients: A Cross-sectional Population-based Study
Rick Waalboer-Spuij, Loes M. Hollestein, Tamar E.C. Nijsten, Lonneke V. van de Poll-Franse; on behalf of the BaSQoL Group
Abstract is missing (Short communication)
Abstract
INVESTIGATIVE REPORT
Novel and Recurrent PNPLA1 Mutations in Spanish Patients with Autosomal Recessive Congenital Ichthyosis; Evidence of a Founder Effect
Uxia Esperón-Moldes, Manuel Ginarte Val, Laura Rodríguez-Pazos, Laura Fachal, José Manuel Azaña, María Barberá Fons, Mónica Viejo Diaz, Ana Vega
Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of rare non-syndrome diseases that affect cornification. PNPLA1 is one of the 12 related genes identified so far. Mutation screening of this gene has resulted in the identification of 13 individuals, from 10 families, who carried 7 different PNPLA1 mutations. These mutations included two missense, two frameshift and 3 nonsense, 3 of them ...
Abstract
SHORT COMMUNICATION
Keratitis-Ichthyosis-Deafness Syndrome: Early Death Caused by the GJB2 Mutation p.Gly12Arg
Clothilde Godillot, Maella Severino-Freire, Vincent Michaud, Franck Boralevi, Christine Labrèze, Vincent Guigonis , Giuliana Onnis, Fanny Morice-Picard, Juliette Mazereeuw-Hautier
Abstract is missing (Short communication)
Abstract
CLINICAL REPORT
Dupilumab versus Cyclosporine for Treatment of Moderate-to-Severe Atopic Dermatitis in Adults: Indirect Comparison Using the Eczema Area and Severity Index
Lieneke F.M. Ariëns, Abhijit Gadkari, Harmieke van Os-Medendorp, Rajeev Ayyagari, Emi Terasawa, Andreas Kuznik, Zhen Chen, Gaëlle Bégo-Le Bagousse, Yufang Lu, Elena Rizova, Neil M.H. Graham, Gianluca Pirozzi, Marjolein De Bruin-Weller, Laurent Eckert
Dupilumab is approved for uncontrolled moderate-to-severe atopic dermatitis (AD), and cyclosporine for severe AD for ≤ 1 year. The efficacy of these treatments was compared indirectly. Regression models used pooled patient-level data to estimate response (Eczema Area and Severity Index (EASI) EASI-50/EASI-75 at weeks 12–16 and 24–30) to dupilumab 300 mg every 2 weeks (weeks; CHRONOS [NCT02 ...
Abstract
INVESTIGATIVE REPORT
Topical Corticosteroid Phobia Among Healthcare Professionals Using the TOPICOP Score
Lies Lambrechts, Liesbeth Gilissen, Marie-Anne Morren
Corticophobia is a major problem in adherence to therapy. This study examined corticophobia among healthcare professionals using the Topical Corticosteroid Phobia (TOPICOP) questionnaire. The TOPICOP questionnaire was adapted for use with professionals (TOPICOP-P). Four groups of professionals: pharmacists, paediatricians, general practitioners and dermatologists were observed. The mean global TOP ...
Abstract
CLINICAL REPORT
Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study
Florian Anzengruber, Matthias Augustin, Marc A. Radtke, Diamant Thaci, Nikhil Yawalkar, Markus Streit, Kristian Reich, Mathias Drach, Christina Sorbe, Lars E. French, Ulrich Mrowietz, Julia-Tatjana Maul, Peter H. Itin, Alexander A. Navarini
Psoriasis can involve the skin, joints, nails and cardiovascular system and result in a significant impairment in quality of life. Studies have shown a lower response rate in smokers, and smoking is a trigger factor for psoriasis. The aim of this study was therefore to analyse the response to systemic therapies for psoriasis, with a focus on smoking. Prospectively collected data from patients with ...
Abstract
CLINICAL REPORT
Economic Burden of Adult Patients with Moderate to Severe Atopic Dermatitis Indicated for Systemic Treatment
Lieneke F.M. Ariëns, Kirsten J.M. van Nimwegen, Marjan Shams, Digna T. de Bruin, Jorien van der Schaft, Harmieke van Os-Medendorp, Marjolein De Bruin-Weller
Given the introduction of new therapies targeting specific immune pathways for atopic dermatitis (AD), information on the economic burden of AD patients is needed. Direct costs (medication use and healthcare resource utilization) and costs of productivity loss were studied in 90 adult patients with AD indicated for systemic treatment. Costs were calculated for patients with controlled (Investigato ...
Abstract
QUIZ
An Unusual Birthmark on the Scalp: A Quiz
Yue-Tong Qian, Jin-Yuan Ma, Sergio Vano-Galvan, Jia-Wei Liu, Wei Liu, Dong-Lai Ma
Abstract is missing (Quiz)
Abstract
CLINICAL REPORT
Interest in Skin Cancer in Urban Populations: A Retrospective Analysis of Google Search Terms in Nine Large German Cities
Linda Tizek, Maximilian C. Schielein, Melvin Rüth, Rolf-Markus Szeimies, Wolfgang G. Philipp-Dormston, Stephan A. Braun, Christine Hecker, Bernadette Eberlein, Tilo Biedermann, Alexander Zink
Skin cancer is a major public health issue, which could be reduced through prevention programmes. How­ever, prevention utilization is not very prevalent. It is therefore important to understand individuals’ interest in skin cancer. Google AdWords Keyword Planner was used to identify the search volume of terms relating to skin cancer in 9 German cities between July 2014 and June 2018. From a tot ...
Abstract
SHORT COMMUNICATION
Effect of Omega-3 Supplementation on Quality of Life in Patients with Psoriasis: A Digital Survey-based Study
Anders D. Andersen, Alexander Almegaard, Anders Nikolai Ørsted Schultz, John Robert Zibert
Abstract is missing (short communication)
Abstract
SHORT COMMUNICATION
Palmoplantar Keratoderma and Woolly Hair Revealing Asymptomatic Arrhythmogenic Cardiomyopathy
Liliana Guerra, Monia Magliozzi, Anwar Baban, Corrado Di Mambro, Giovanni Di Zenzo, Antonio Novelli, May El Hachem, Giovanna Zambruno, Daniele Castiglia
Abstract is missing (short communication)
Abstract
CLINICAL REPORT
Autochthonous Cutaneous Larva Migrans in France and Europe
Pascal Del Giudice, Sophie Hakimi, Frédéric Vandenbos, Catherine Magana, Thomas Hubiche
Cutaneous larva migrans is a dermatitis, typically acquired in warm tropical or sub-tropical countries, caused by skin migration of the larvae of animal nematodes (mainly Ancylostoma braziliense and occasionally Ancylostoma caninum and Uncinaria stenocephala) (1–3). The larvae penetrate the skin after contact with infected soil and cause a typical creeping eruption. Patients with cutaneous larva ...
Abstract
SHORT COMMUNICATION
Two Cancer Patients Receiving Dupilumab for Treatment of Atopic Dermatitis
Emilie Fowler, Jordan Rosen, Hadar Lev-Tov, Gil Yosipovitch
Abstract is missing (short communication)
Abstract
CLINICAL REPORT
Novel DSP Spectrin 6 Region Variant Causes Neonatal Erythroderma, Failure to Thrive, Severe Herpes Simplex Infections and Brain Lesions
Svetlana Vakkilainen, Laura Puhakka, Paula Klemetti, Kaarina Heiskanen, Mikko Seppänen, Mikko Muona, Celine Posseme, Duffy Darragh, Timo Väisänen, Outi Elomaa, Maarit Palomäki, Harri Saxén, Annamari Ranki, Katariina Hannula-Jouppi
Desmoplakin (DSP) and Desmoglein 1 (DSG1) variants result in skin barrier defects leading to erythroderma, palmoplantar keratoderma and variable [AQ4] other features. Some DSG1 variant carriers present with SAM syndrome (Severe dermatitis, multiple Allergies, Metabolic wasting) and a SAM-like phenotype has been reported in 4 subjects with different heterozygous DSP variants. We report here a patie ...
Abstract
QUIZ
Progressive Erythroderma without Malignancy in the Skin: A Quiz
Hiroyuki Irie, Teruki Dainichi, Yo Kaku, Kenji Kabashima
Abstract is missing (Quiz)
Abstract
SHORT COMMUNICATION
Secukinumab Provides Rapid Relief From Itching and Pain in Patients with Moderate-to-Severe Psoriasis: Patient Symptom Diary Data from Two Phase 3, Randomized, Placebo-controlled Clinical Trials
Gil Yosipovitch, Jennifer Soung, Jonathan Weiss, Elisa Muscianisi, Xiangyi Meng, Isabelle Gilloteau, Boni E. Elewski
Abstract is missing (Short communication)
Abstract
CLINICAL REPORT
Sunbed Use Increases Cutaneous Squamous Cell Carcinoma Risk in Women: A Large-scale, Prospective Study in Sweden
Gustav Boelsggard Christensen, Christian Ingvar, Linda Werner Hartman, Håkan Olsson, Kari Nielsen
The incidence of cutaneous squamous cell carcinoma has increased rapidly in Sweden in the past decades. Here, we present a prospective study of the Melanoma in Southern Sweden (MISS)-cohort, with 29,460 participating women in southern Sweden that investigates the risk factors for cutaneous squamous cell carcinoma. Data on the host and skin cancer risk factors were collected through questionnaires ...
Abstract
SHORT COMMUNICATION
Vitiligo Repigmentation with Melanoma Progression During Pembrolizumab Treatment
Charlée Nardin, Fabien Pelletier, Eve Puzenat, François Aubin
Abstract is missing (Short communication)
Abstract
QUIZ
Dense Papules on the Face: A Quiz
Hongmei Zhou, Qiang Zhao, Lihong Zhao, Qian Shang, Jing Li, Songmei Geng
Abstract is missing (Quiz)
Abstract
CLINICAL REPORT
Direct and Indirect Effects of Crisaborole Ointment on Quality of Life in Patients with Atopic Dermatitis: A Mediation Analysis
Eric L. Simpson, Gil Yosipovitch, Andrew G. Bushmakin, Joseph C. Cappelleri, Thomas Luger, Sonja Ständer, Wynnis L. Tom, William C. Ports, Michael A. Zielinski, Anna M. Tallman, Huaming Tan, Robert A. Gerber
Crisaborole ointment is a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis. Using pooled data from two phase 3 studies (NCT02118766/NCT02118792), mediation modeling determined the interrelationship among pruritus, quality of life (QoL), and treatment. Patients aged ≥ 2 years received crisaborole ointment 2% or vehicle twice daily for 28 days. Q ...
Abstract
SHORT COMMUNICATION
Cellular Angiofibroma: Case Report of a Unique Subungual Presentation
Christophe Perrin, Giuseppe E. Cannata, Florence Pedeutour, Bérengère Dadone-Montaudié, Damien Ambrosetti
Abstract is missing (Short communication)
Abstract
BOOK REVIEW
Skin Barrier Function
Magnus Lindberg
Abstract is missing (Book review)
Abstract
BOOK REVIEW
Current Problems in Dermatology, Vol. 48. Tattooed Skin and Health
Kristian Thestrup-Pedersen
Abstract is missing (Book review)
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