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These articles have been accepted for publication in Acta Dermato-Venereologica and are currently being edited and typeset. Readers should note that articles published below have been fully refereed, but have not been through the copy-editing and proof correction process. Only Abstract is possible to read. When this process is finalized the complete paper will be able to find.
SHORT COMMUNICATION
Changes in Androgen Receptor Expression as a Molecular Marker of Progression from Normal Epithelium to Invasive Cancer in Elderly Patients with Penile Squamous Cell Carcinoma
Valerio Gaetano Vellone, Emanuele Cozzani, Leonardo Peñuela, Roberto Russo, Bruno Spina, Carlo Toncini, Carlo Terrone, Aurora Parodi
Abstract is missing (Short Communication)
Abstract
SHORT COMMUNICATION
A Case of Subcutaneous Infection with Mycobacterium mageritense Identified by Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry
Tomohiro Oiwa, Teruasa Murata, Tetsuya Honda, Satoshi Nakano, Kenji Kabashima
Abstract is missing (Short communication)
Abstract
SHORT COMMUNICATION
Efficacy of Oral Ruxolitinib in a Patient with Refractory Chronic Spontaneous Urticaria
Atsushi Fukunaga, Mitsuhiro Ito, Chikako Nishigori
Abstract is missing (Short communication)
INVESTIGATIVE REPORT
Granular IgA Deposits in the Skin of Patients with Coeliac Disease: Is it Always Dermatitis Herpetiformis?
Veronica Bonciolini, Emiliano Antiga, Beatrice Bianchi, Elena Del Bianco, Alessandra Ninci, Vincenza Maio, Nicola Pimpinelli, Marzia Caproni
Coeliac disease is an immune-mediated enteropathy driven by gluten, which can be associated with dermatitis herpetiformis. The presence of granular IgA deposits, detected by direct immunofluorescence, is the hallmark of dermatitis herpetiformis; nevertheless, IgA deposits have also been demonstrated in healthy skin of patients with coeliac disease. The main objective of this study was to investiga ...
REVIEW
Melanogenesis Inhibitors
Sulekha Kumari, Steven Tien Guan Thng, Navin Kumar Verma, Hemant K. Gautam
Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles. These hyperpigmentary skin disorders can significantly impact an individual’s appearance, and may cause emotional and psychological distress and reduced quality of life. A large number of melanogenesis inhibitors have been developed, b ...
REVIEW
Antioxidative Phytochemicals Accelerate Epidermal Terminal Differentiation via the AHR-OVOL1 Pathway: Implications for Atopic Dermatitis
Masutaka Furue, Akiko Hashimoto-Hachiya, Gaku Tsuji
Aryl hydrocarbon receptor (AHR) is a chemical sensor that is expressed abundantly in epidermal keratinocytes. Oxidative AHR ligands induce the production of reactive oxygen species. However, antioxidant AHR ligands inhibit reactive oxygen species generation via activation of nuclear factor-erythroid 2-related factor-2, which is a master switch for antioxidative signalling. In addition, AHR signall ...
SHORT COMMUNICATION
Secondary Cutaneous Epstein–Barr Virus-associated Diffuse Large B-cell Lymphoma with Hodgkin/Reed-Sternberg-like Cells in a Patient with Angioimmunoblastic T-cell Lymphoma
Hao Chen, Yan-ning Xue, Chong-mei Xin, Jing-shu Xiong, Xiao Ni, Jian-Fang Sun
Abstract is missing (Short communication)
SHORT COMMUNICATION
A Case of Ankyloblepharon-ectodermal Defects-cleft Lip/palate-syndrome with Choanal Atresia and Skin Erosions: Phenotypic Variability of TP63-related Disorders
Luana Niculescu, Matias Wagner, Dominik S. Westphal, Marcus Fischer, Walter Mihatsch, Anke Prothmann, Thomas Ruzicka, Andreas Wollenberg, Hans Wolff, Heinrich Schmidt, Kathrin A. Giehl
Abstract is missing (Short communication)
SHORT COMMUNICATION
Effects of Film Dressings on Itch Hypersensitivity Using Murine Dry Skin Models
Tomoyuki Iwanaga, Mitsutoshi Tominaga, Yui Hirata, Hironori Matsuda, Tomomasa Shimanuki, Hideoki Ogawa, Kenji Takamori
Abstract is missing (Short communication)
SHORT COMMUNICATION
Chlamydiales Bacterial Sequences in Lesional and Healthy Skin of Patients with Parapsoriasis
Kati Hokynar, Alexander Salava, Eero Vesterinen, Antti Lauerma, Annamari Ranki, Mirja Puolakkainen
Abstract is missing (Short communication)
SHORT COMMUNICATION
Eccrine Porocarcinoma of the Skin is Rising in Incidence in the East of England
Peter K.C. Goon, Puran Gurung, Nick J. Levell, Priya Subramanian, Adrian S.W. Yong, Kevin Y.C. Lee, Laszlo Igali, David Greenberg, Syed N. Shah, Eunice K.H. Tan
Abstract is missing (Short communication)
SHORT COMMUNICATION
Methotrexate for the Treatment of Recalcitrant Primary Localized Cutaneous Amyloidosis: A Case Series
Carolyn M. Stull, Hong Liang Tey, Gil Yosipovitch
Abstract is missing (Short communication)
INVESTIGATIVE REPORT
Sub-optimal Application of a High SPF Sunscreen Prevents Epider­mal DNA Damage in Vivo
Antony R. Young, Jessica Greenaway, Graham I. Harrison, Karl P. Lawrence, Robert Sarkany, Thierry Douki, France Boyer, Gwendal Josse, Emmanuel Questel, Camille Monteil, Ana B. Rossi
The cyclobutane pyrimidine dimer (CPD) is a potentially mutagenic DNA photolesion that is the basis of most skin cancers. There are no data on DNA protection by sunscreens under typical conditions of use. The study aim was to determine such protection, in phototypes I/II, with representative sunscreen-user application. A very high SPF formulation was applied at 0.75, 1.3 and 2.0 mg/cm2. Unprotecte ...
SHORT COMMUNICATION
A Case of Pityriasis Rubra Pilaris Treated Successfully with the Phosphodiesterase-4 Inhibitor Apremilast
Maria Cho, Tetsuya Honda, Chiyuki Ueshima, Tatsuki Kataoka, Atsushi Otsuka, Kenji Kabashima
Abstract is missing (Short commuication)
INVESTIGATIVE REPORT
Modulation of Itch by Localized Skin Warming and Cooling
Kristen M. Sanders, Takashi Hashimoto, Kent Sakai, Tasuku Akiyama
Skin thermal changes modulate itch sensitivity. However, the mechanisms of this modulation are still unclear. Using mouse models of acute and chronic itch, we investigated whether local innocuous thermal stimulation of the skin alters itch sensitivity and if blockade of thermosensitive transient receptor potential (TRP) channels can reduce these changes. Localized thermal changes were achieved by ...
CLINICAL REPORT
Nocebo Effects and Scratching Behaviour in Itch
Danielle J.P. Bartels, Antoinette I.M. van Laarhoven, Peter C.M. van de Kerkhof, Andrea W.M. Evers
Nocebo effects, i.e. reduced treatment effects due to patients’ negative expectations, play a role in itch. Recent studies have shown that nocebo effects can be induced experimentally in itch and even be reversed into the placebo effect. It is not known whether these effects generalize to itch-associated scratching behaviour. The aim of this study was to determine whether induction and reversion ...
CLINICAL REPORT
Assessment of the Effect of 3% Diclofenac Sodium on Photodamaged Skin by Means of Reflectance Confocal Microscopy
Gonzalo Segurado-Miravalles, Natalia Jiménez-Gómez, Oscar Muñoz Moreno-Arrones, Ivette Alarcón-Salazar, Adrian Alegre-Sánchez, David Saceda-Corralo, Pedro Jaén-Olasolo, Salvador González-Rodríguez
Treatment of actinic keratosis with 3% diclofenac sodium w/w in hyaluronic acid is associated with a concomitant improvement in signs of photodamaged skin. However this effect has not yet been examined in depth. Twenty patients with actinic keratosis and signs of photodamaged skin were studied. They received treatment with diclofenac sodium w/w in hyaluronic acid for 2 months. Clinical and reflect ...
CLINICAL REPORT
Livedoid Vasculopathy: A French Observational Study Including Therapeutic Options
Emma Gardette, Philippe Moguelet, Jean-David Bouaziz, Dan Lipsker, Olivier Dereure, Francois Le Pelletier, Catherine Lok, Thierry Maisonobe, Didier Bessis, Jacqueline Conard, Camille Francès, Stéphane Barete
Livedoid vasculopathy is a rare thrombotic cutaneous disease. This observational study aimed to assess the clinical and biological features of livedoid vasculopathy and the efficacy of treatments. Patients enrolled had typical livedoid vasculopathy both clinically and histologically. Investigation of thrombophilia was performed. Electromyography was undertaken in the presence of symptoms suggestin ...
INVESTIGATIVE REPORT
Genotype–Phenotype Correlations of Dystrophic Epidermolysis Bullosa in India: Experience from a Tertiary Care Centre
Vamsi K. Yenamandra, Shamsudheen K. Vellarikkal, Madhumita R. Chowdhury, Rijith Jayarajan, Ankit Verma, Vinod Scaria, Sridhar Sivasubbu, Subrata Basu Ray, Amit K. Dinda, Madhulika Kabra, Vinod K. Sharma, Gomathy Sethuraman
Recent advances in the field of genomics have seen the successful implementation of whole exome sequencing as a rapid and efficient diagnostic strategy in several genodermatoses. The aim of this study was to explore the potential of molecular studies in dystrophic epidermolysis bullosa (DEB) in India. Whole exome sequencing was performed using genomic DNA from each case of epidermolysis bullosa, f ...
INVESTIGATIVE REPORT
Mortality in Patients with Bullous Pemphigoid: A Retrospective Cohort Study, Systematic Review and Meta-analysis
Khalaf Kridin, Reuven Bergman
There is little consensus regarding mortality data in bullous pemphigoid (BP). The aim of this study was to evaluate mortality among a relatively large cohort of Israeli patients with BP and to perform a meta-analysis synthesizing existing data on 1-year mortality rates of patients with BP. This retrospective cohort study of 287 patients diagnosed with BP between 2000 and 2015 compared the mortali ...
SHORT COMMUNICATION
Nanostring Analysis of Skin Biopsies from Patients with Henoch-Schönlein Purpura Reveals Genes Associated with Pathology and Heterogeneity in the Disease Process
Yingrou Tan, Jackson Liang Yao Li, Bernett Teck Kwong Lee, Josephine Lum, Zacharias Aloysius Dwi Pramono, Maximilien Evrard, Michael Poidinger, Hong Liang Tey, Lai Guan Ng
Abstract is missing (Short communication)
CLINICAL REPORT
Longer Duration of Untreated Psychosis is Associated with Poorer Outcomes for Patients with Delusional Infestation
Dmitry V. Romanov, Peter Lepping, Anthony Bewley, Markus Huber, Roland W. Freudenmann, Andrey Lvov, Stephen Bertel Squire, Eric O. Noorthoorn
We examined the association between the duration of untreated psychosis and outcome for patients with delusional infestation. This multi-centre international study included consecutive 211 patients. Illness severity was evaluated at first presentation and outcome was measured with the Clinical Global Impression scale (CGI) at baseline and follow-up. A regression analysis showed a clear clinical an ...
BOOK REVIEW
Genetic Skin Disorders, 3rd edition
Anders Vahlquist
Abstract is missing (Book review)
BOOK REVIEW
Hurwitz Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence, 5th Edition
Regina Fölster-Holst
Abstract is missing (Book review)
BOOK REVIEW
Skin Barrier Function
Magnus Lindberg
Abstract is missing (Book review)
BOOK REVIEW
Current Problems in Dermatology, Vol. 48. Tattooed Skin and Health
Kristian Thestrup-Pedersen
Abstract is missing (Book review)
BOOK REVIEW
Chemical Immunology and Allergy, Vol. 100. History of Allergy
Carl-Fredrik Wahlgren
Abstract is missing (Book review)