You are not logged in. Press here to login.

Content

List volumes - List articles in this issue

Original report

Cognitive and emotional problems in patients after cerebral meningioma surgery

doi: 10.2340/16501977-1795

Abstract:

OBJECTIVES: To determine long-term cognitive complaints and symptoms of depression or anxiety in patients following surgery for a cerebral meningioma, and to examine factors associated with these outcomes.
DESIGN: Cross-sectional study.
Patients: Patients operated on for a cerebral meningioma in the University Medical Center Utrecht, The Netherlands, between 2007 and 2009.
METHODS: Clinical data were retrieved from medical files. Patients completed a postal questionnaire. Cognitive complaints were measured with the Cognitive Failures Questionnaire. A score above 43.5 was defined as presence of cognitive complaints. Anxiety and depressive symptoms were measured with the Hospital Anxiety and Depression Scale, and were considered present if the scale score was ≥ 8.
RESULTS: The response rate was 76% (n = 136). Mean time after operation was 32.6 months (standard deviation 10.6 months). Overall, 40% of patients experienced cognitive and/or emotional problems. Thirty-one patients (23%) experienced cognitive complaints, 39 (29%) showed anxiety, and 31 (23%) showed depressive symptoms. Country of birth and previous depression/burn-out were the most important factors. Scores on all outcome measures were related to each other.
CONCLUSION: Forty percent of patients experienced cognitive or emotional problems following surgery for a cerebral meningioma. Screening for these problems is therefore important in order to provide patients with the care they require as soon as possible.

Authors:

Sanne van der Vossen , Vera P.M. Schepers, Jan Willem Berkelbach van der Sprenkel , Johanna M. A. Visser-Meily, Marcel W.M. Post
Rudolf Magnus Institute of Neuroscience and Center of Excellence for Rehabilitation Medicine, University Medical Center Utrecht and Rehabilitation Center De Hoogstraat, Utrecht, The Netherlands

References

1. Ostrom QT, Gittleman H, Farah P, Ondracek A, Chen Y, Wolinsky Y, Kruchko C, Barnholtz-Sloan JS, CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States 2006–2010. Neuro-Oncol 2013; 15 (Suppl 2): ii1–ii56.

2. Whittle IR, Smith C, Navoo P, Collie D. Meningiomas. Lancet 2004; 363: 1535–1543.

3. Cahill KS, Claus EB. Treatment and survival of patients with nonmalignant intracranial meningioma: results from the Surveillance, Epidemiology, and End Results Program of the National Cancer. J Neurosurg 2011; 115: 259–267.

4. McCarthy BJ, Davis FG, Freels S, Surawicz TS, Damek DM, Grutsch J, et al. Factors associated with survival in patients with meningioma. J Neurosurg 1998; 88: 831–839.

5. Tucha O, Smely C, Lange KW. Effects of surgery on cognitive functioning of elderly patients with intracranial meningioma. Br J Neurosurg 2001; 15: 184–188.

6. Tucha O, Smely C, Preier M, Becker G, Paul GM, Lange KW. Preoperative and postoperative cognitive functioning in patients with frontal meningiomas. J Neurosurg 2003; 98: 21–31.

7. Krupp W, Klein C, Koschny R, Holland H, Seifert V, Meixensberger J. Assessment of neuropsychological parameters and quality of life to evaluate outcome in patients with surgically treated supratentorial meningiomas. Neurosurgery 2009; 64: 40–47.

8. Dijkstra M, Van Nieuwenhuizen D, Stalpers LJA, Wumkes M, Waagemans M, Vandertop WP, et al. Late neurocognitive sequelae in patients with WHO grade I meningioma. J Neurol Neurosurg Psychiatry 2009; 80: 910–915.

9. Van Nieuwenhuizen D, Klein M, Stalpers LJA, Leenstra S, Heimans JJ, Reijneveld JC. Differential effect of surgery and radiotherapy on neurocognitive functioning and health-related quality of life in WHO grade I meningioma patients. J Neurooncol 2007; 84: 271–278.

10. Lannoo E, Colardyn F, Vandekerckhove T, De Deyne C, De Soete G, Jannes C. Subjective complaints versus neuropsychological test performance after moderate to severe head injury. Acta Neurochir (Wien) 1998; 140: 245–253.

11. Duits A, Munnecom T, Van Heugten C, Van Oostenbrugge RJ. Cognitive complaints in the early phase after stroke are not indicative of cognitive impairment. J Neurol Neurosurg Psychiatry 2008; 79: 143–146.

12. Liik M, Vahter L, Gross-Paju K, Haldre S. Subjective complaints compared to the results of neuropsychological assessment in patients with epilepsy: the influence of comorbid depression. Epilepsy Res 2009; 84: 194–200.

13. Piazzini A, Canevini MP, Maggiori G, Canger R. The perception of memory failures in patients with epilepsy. Eur J Neurol 2001; 8: 613–620.

14. Passier PECA, Visser-Meily JMA, Van Zandvoort MJE, Post MWM, Rinkel GJE, Van Heugten C. Prevalence and determinants of cognitive complaints after aneurysmal subarachnoid hemorrhage. Cerebrovasc Dis 2010; 29: 557–563.

15. Lang DA, Neil-Dwyer G, Garfield J. Outcome after complex neurosurgery: the caregiver’s burden is forgotten. J Neurosurg 1999; 91: 359–363.

16. Farrin L, Hull L, Unwin C, Wykes T, David A. Effects of depressed mood on objective and subjective measures of attention. J Neuro­psychiatry Clin Neurosci 2003; 15: 98–104.

17. Gallo LC, Malek MJ, Gilbertson AD, Moore JL. Perceived cognitive function and emotional distress following coronary artery bypass surgery. J Behav Med 2005; 28: 433–442.

18. Hohman TJ, Beason-Held LL, Resnick SM. Cognitive complaints, depressive symptoms, and cognitive impairment: are they related? J Am Geriatr Soc 2011; 59: 1908–1912.

19. Stulemeijer M, Vos PE, Bleijenberg G, Van der Werf SP. Cognitive complaints after mild traumatic brain injury: things are not always what they seem. J Psychosom Res 2007; 63: 637–645.

20. Sullivan B, Payne TW. Affective disorders and cognitive failures: a comparison of seasonal and nonseasonal depression. Am J Psychiatry 2007; 164: 1663–1667.

21. Van Roijen L, Essink-Bot ML, Koopmanschap MA, Bonsel G, Rutten FF. Labor and health status in economic evaluation of health care. The Health and Labor Questionnaire. Int J Technol Assess Health Care 1996; 12: 405–415.

22. Broadbent DE, Cooper PF, FitzGerald P, Parkes KR. The Cognitive Failures Questionnaire (CFQ) and its correlates. Br J Clin Psychol 1982; 21: 1–16.

23. Merckelbach H, Muris P, Nijman H, de Jong PJ. Self-reported cognitive failures and neurotic symptomatology. Person Individ Diff 1996; 20: 715–724.

24. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361–370.

25. Spinhoven P, Ormel J, Sloekers PP, Kempen GIJM, Speckens AEM, Van Hemert AM. A validation study of the Hospital Anxiety and Depression Scale (HADS) in different groups of Dutch subjects. Psychol Med 1997; 27: 363–370.

26. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK. WHO classification of tumours of the central nervous system. 4th ed. Lyon: IARC; 2007.

27. Pfeifer S, Van Os J, Hanssen M, Delespaul P, Krabbendam L. Subjective experience of cognitive failures as possible risk factor for negative symptoms of psychosis in the general population. Schizophr Bull 2009; 35: 766–774.

28. Boomsma DI. Genetic analysis of cognitive failures (CFQ): a study of Dutch adolescent twins and their parents. Eur J Personality 1998; 12: 321–330.

29. Bjelland I, Dahl AA, Haug T, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Research 2002; 53: 69–77.

30. Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale: Lawrence Erlbaum Associates; 1988.

31. Passier PECA, Visser-Meily JMA, Van Zandvoort MJE, Rinkel GJE, Lindeman E, Post MWM. Predictors of long-term health-related quality of life in patients with aneurysmal subarachnoid hemorrhage. NeuroRehabilitation 2012; 30: 137–145.

32. Visser-Meily JMA, Rhebergen ML, Rinkel GJE, Van Zandvoort MJ, Post MWM. Long-term health-related quality of life after aneurysmal subarachnoid hemorrhage: relationship with psychological symptoms and personality characteristics. Stroke 2009; 40: 1526–1529.

33. Passier PECA, Visser-Meily JMA, Rinkel GJE, Lindeman E, Post MWM. Life satisfaction and return to work after aneurysmal subarachnoid haemorrhage. J Stroke Cerebrovasc Dis 2011; 20: 324–329.

34. Barker-Collo SL, Feigin VL, Lawes CMM, Parag V, Senior H, Rodgers A. Reducing attention deficits after stroke using attention process training: a randomized controlled trial. Stroke 2009; 40: 3293–3298.

35. Andrewes HE, Drummond KJ, Rosenthal M, Bucknill A, Andrewes DG. Awareness of psychological and relationship problems amongst brain tumour patients and its association with carer distress. Psycho-Oncology 2013 Mar 19 [Epub ahead of print].

36. Visser-Keijzer AC, Jong B, Deelman BG, Berg IJ, Gerritsen MJJ. Subjective change in emotive, cognition and behaviour after stroke: factors affecting the perception of patients and partners. J Clin Exp Neuropsychol 2002; 24: 1032–1045.

37. Hackett ML, Yapa C, Parag V, Anderson CS. Frequency of depression after stroke: a systematic review of observational studies. Stroke 2005; 36: 1330–1340.

38. Gale CR, Allerhand M, Deary IJ, HALCyon Study Team. Is there a bidirectional relationship between depressive symptoms and cognitive ability in older people? A prospective study using the English Longitudinal Study of Ageing. Psychol Med 2012; 42: 2057–2069.

39. Lewis-Fernández R, Hinton DE, Laria AJ, Patterson EH, Hofmann SG, Craske MG, et al. Culture and the anxiety disorders: recommendations for DSM-V. Depress Anxiety 2010; 27: 212–229.

40. Mensah SA, Beavis JM, Thapar AK, Kerr M. The presence and clinical implications of depression in a community population of adults with epilepsy. Epilepsy Behav 2006; 8: 213–219.



Related articles

There are no related articles.


Actions


Abstract

Full text

PDF

Supplementary


There is no supplementary for this article.

Related articles


Click here to show related articles

Print information


Volume 46, Issue 5

DOI: 10.2340/16501977-1795

Pages: 430-437

View at PubMed