Content » Vol 85, Issue 1

Investigative Report

UVB 311 nm Tolerance of Vitiligo Skin Increases with Skin Photo Type

Anne-Lou D.B. Caron-Schreinemachers , Melanie M. Kingswijk , Jan D. Bos , Wiete Westerhof
DOI: 10.1080/00015550410022203


It is assumed that skin is protected against sunburn by melanin. In patients with vitiligo, there are white patches in the normal pigmented skin. We noticed that there is a difference in burning capacity of these white patches between people with different skin types. With UVB 311 nm lamps, we irradiated both lesional and non-lesional skin with increasing doses in 33 patients with vitiligo, divided into 5 groups according to skin type (II-VI). Twenty-four hours later we assessed the minimal erythema dose and found a correlation between skin type and UV sensitivity in both lesional skin and normal skin. We suggest that there must be a protection mechanism, other than that offered by melanin pigmentation. The antioxidant status may play a role in this phenomenon.


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