Content » Vol 92, Issue 3


Host Defence Against Candida albicans and the Role of Pattern-recognition Receptors

Gerd G. Gauglitz, Helene Callenberg , Günther Weindl, Hans C. Korting
DOI: 10.2340/00015555-1250


Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors responsible for recognition of special structures of C. albicans, which are known to activate intracellular signals that finally lead to directed and efficient host defence.


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