Content » Vol 92, Issue 3

Review

Host Defence Against Candida albicans and the Role of Pattern-recognition Receptors

Gerd G. Gauglitz, Helene Callenberg, Günther Weindl, Hans C. Korting
DOI: 10.2340/00015555-1250

Abstract

Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors responsible for recognition of special structures of C. albicans, which are known to activate intracellular signals that finally lead to directed and efficient host defence.

Significance

Supplementary content

Comments

Not logged in! You need to login/create an account to comment on articles. Click here to login/create an account.