Content - Volume 73, Issue 5

Editor's choice in this issue

All articles

Why hair turns green
Sticherling M, Christophers E
Pages: 321-322
Abstract  PDF
Quantitative and 3-dimensional analysis of Langerhans' cells following occlusion with patch tests using confocal laser scanning microscopy
Emilson A, Lindberg M, Forslind B, Scheynius A.
Quantitative and detailed 3-dimensional (3-D) morphological information can be obtained from the same tissue volume using a confocal laser scanning microscope (CLSM). In the present study, we used CLSM for evaluation of Langerhans' cells (LC) in human skin at 0 h, 24 h and 48 h following occlusion with patch tests for 48 h. The relative volume of epidermal CD1a reactivity was quantified with CLSM ...
Pages: 323-329
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Skin disease in immunosuppressed patients in relation to epidermal Langerhans' cells.
Bergfelt L, Larkö O, Blohmé I.
Warts and skin tumours are common in renal transplant recipients (RTR). The increased susceptibility to skin lesions has been attributed to immunosuppressive treatments. The epidermal antigen-presenting Langerhans' cell (LC) is important for cutaneous immunosurveillance. The number of LC is reduced by UV light and by immunosuppressive therapy. One hundred and seventy-three immunosuppressed patient ...
Pages: 330-334
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Electrical measurement of the water content of the stratum corneum in vivo and in vitro under various conditions: comparison between skin surface hygrometer and corneometer in evaluation of the skin surface hydration state.
Hashimoto-Kumasaka K, Takahashi K, Tagami H.
Two commercially available electrical instruments which evaluate the hydration state of the skin surface were compared in in vitro and in vivo experiments. The skin surface hygrometer (Skicon-200) employs high-frequency conductance, whereas the corneometer (CM 420, CM 820) uses electrical capacitance to determine the level of hydration. In a simulation model of in vivo stratum corneum (SC), the hi ...
Pages: 335-339
Abstract  PDF
Water and ion distribution profiles in human skin.
von Zglinicki T, Lindberg M, Roomans GM, Forslind B.
Bulk sample x-ray microanalysis (XRMA) of human gluteal skin was performed to provide data on water and ion profiles over the epidermal cross section. All samples were analyzed both in the frozen hydrated state and in the frozen dried state. This allows, for the first time, a quantitative determination of the local water content in different strata of the skin. A steep water gradient was found in ...
Pages: 340-343
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Effects of short-time hydration on skin extensibility.
Auriol F, Vaillant L, Machet L, Diridollou S, Lorette G.
Vertical cutaneous extensibility was studied before and after 1, 2, 5 and 10 min hydration by application of tap water. After hydration, we noted an increase in all rheological parameters linked to elasticity whereas viscosity and hysteresis parameters were unmodified. These modifications took place from the first minute and increased thereafter. Men and women showed identical values prior to hydr ...
Pages: 344-347
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An endocrinological study of patients with primary cutis verticis gyrata.
Palazzo R, Schepis C, Ruggeri M, Baldini L, Pizzimenti A, Arcoraci V, Spina E.
An endocrinological study of 15 psychiatric patients with primary cutis verticis gyrata (CVG) and 7 control patients was carried out. The investigation of the pituitary-gonadal axis, pituitary-adrenal axis, pituitary-thyroid axis, prolactin and human growth hormone (basal values and circadian biorhythms) did not show any significant difference between the CVG and the control patients. Only levels ...
Pages: 348-349
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Initiation of the effects of acrivastine and cetirizine on histamine-induced wheals and itch in human skin.
Lahti A, Haapaniemi T.
The initiation of the antihistamine effect of a single dose of acrivastine (8 mg) or cetirizine (10 mg) on wheals and itch induced by histamine dihydrochloride (10 mg/ml) in the prick test was studied in a randomized cross-over design employing 20 healthy medical students. The prick test was performed before ingestion of the drug and after 15, 20, 25, 30, 60 and 90 min and 2, 3 and 4 h. Local symp ...
Pages: 350-351
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Papillomavirus DNA typing analysis in condyloma acuminatum patients and their consorts.
Kiss M, Husz S, Soós J, Dobozy A.
The present study demonstrated human papillomavirus (HPV) infection by means of an in situ HPV DNA hybridization screening test (BIOHIT) in 8 male patients with genital condyloma acuminatum, their asymptomatic female consorts and 6 female patients with vulval condyloma acuminatum. The investigations revealed that all but one of the female consorts were infected by HPV but did not show any clinical ...
Pages: 352-355
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Photopheresis in systemic sclerosis: clinical and serological studies using markers of collagen metabolism.
Zachariae H, Bjerring P, Heickendorff L, Møller B, Wallevik K, Angelo H.
Eight patients with progressive systemic sclerosis were treated with photopheresis or extracorporeal photochemotherapy given on 2 consecutive days every 4 weeks for 5 to 8 months. Previous treatment with immunosuppressive agents or D-penicillamine was discontinued for at least 4 weeks prior to photopheresis. Although IL-2 receptor density in peripheral blood T-lymphocytes decreased significantly i ...
Pages: 356-361
Abstract  PDF
Evaluation of phototoxic properties of some food additives: sulfites exhibit prominent phototoxicity.
Eberlein-König B, Bergner T, Diemer S, Przybilla B.
Additives are used widely to enhance the quality of food products. To identify possible phototoxic properties, 13 food additives (benzoic acid, sodium benzoate, 4-hydroxybenzoic acid, 4-hydroxybenzoic acid methyl ester, 4-hydroxybenzoic ethyl ester, 4-hydroxybenzoic acid propyl ester, p-hydroxybenzoic acid n-butyl ester, benzyl alcohol, sorbic acid, potassium sorbate, propionic acid, sodium disulf ...
Pages: 362-364
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Induction of type IV hypersensitivity to contact allergens in guinea pigs by in vitro haptenized allogenic peritoneal exudate cells.
Helmbold P, Rytter M, Ziegler V, Haustein UF.
The induction of type IV hypersensitivity to contact allergens in guinea pigs has been studied by using allogenic peritoneal exudate cells (> 90% macrophages), which had been incubated primarily in vitro with dinitrochlorobenzene, formaldehyde, potassium dichromate, nickel II sulphate or para-aminobenzoic acid. In these guinea pig sensitization experiments Freund's complete adjuvant was used. In a ...
Pages: 365-369
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Keratinocyte proliferation in epidermal keratinocyte disorders evaluated through PCNA/cyclin immunolabelling and AgNOR counting.
Kanitakis J, Hoyo E, Chouvet B, Thivolet J, Faure M, Claudy A.
The assessment of cell proliferation is important to our understanding of hyperproliferative disorders. In this work we evaluated the proliferation characteristics of epidermal keratinocytes in diseases with abnormal keratinization by two different methods (immunostaining for the proliferating cell nuclear antigen--PCNA and histochemical staining for nucleolar organizer region--associated argyroph ...
Pages: 370-375
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Scanning electron microscopy of scales from pityriasis amiantacea.
Batten TL, White MI, Gregory DW.
The scanning electron microscope has been used to examine scales taken from the scalp of 3 patients with pityriasis amiantacea alone, 3 psoriatic patients with pityriasis amiantacea and one patient with both atopic dermatitis and pityriasis amiantacea. Samples from 2 patients were additionally studied by different fixation techniques and in the frozen hydrated state, but no cementing of the scales ...
Pages: 376-377
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Acanthosis nigricans and bile duct malignancy.
Ravnborg L, Thomsen K.
A case of acanthosis nigricans associated with a metastatic adenocarcinoma is presented. To our knowledge this is the first one reported in the literature. The primary tumour is unknown, but it is presumably a cholangiocarcinoma. The skin changes preceded the detection of malignancy by 2 years, during which the skin lesions progressed though the patient was still in good health. If malignant acant ...
Pages: 378-379
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Neutrophilic dermatosis of the face associated with aortitis syndrome and Hashimoto's thyroiditis.
Nakayama H, Shimao S, Hamamoto T, Munemura C, Nakai A.
This is the first reported case of neutrophilic dermatosis of the face (Sweet's syndrome) associated with aortitis syndrome (Takayasu arteritis) and Hashimoto's thyroiditis. The patient was a 39-year-old Japanese female for whom corticosteroid therapy was effective.
Pages: 380-381
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Toxic pustuloderma induced by ofloxacin.
Tsuda S, Kato K, Karashima T, Inou Y, Sasai Y.
A patient with drug-induced toxic pustuloderma is presented. The patient, who was asthmatic and who was being treated with ofloxacin for bronchitis and pharyngitis, developed intense erythemas followed by subcorneal pustulation associated with fever and a neutrophil leukocytosis. The diagnosis was confirmed by oral readministration of ofloxacin, with the result that pustular eruptions were induced ...
Pages: 382-384
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Interferon alpha-2b treatment of symptomatic chronic vulvodynia associated with koilocytosis.
Larsen J, Peters K, Petersen CS, Damkjaer K, Albrectsen J, Weismann K.
In an open study with identical criteria for diagnosis, 16 female patients with typical symptoms of chronic vulvodynia associated with acetowhitening of the vestibular epithelium and koilocytosis in biopsy specimens received recombinant interferon alpha-2b 5 MIU intralesionally 3 times weekly for 3 weeks or subcutaneously 3 times weekly for 8 weeks. Three months after end of therapy, clinical symp ...
Pages: 385-387
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Supervised four-week heliotherapy alleviates the long-term course of psoriasis.
Snellman E, Aromaa A, Jansén CT, Lauharanta J, Reunanen A, Jyrkinen-Pakkasvirta T, Luoma J, Waal J.
The long-term effects of psoriasis heliotherapy were studied in a randomized cross-over trial with a 2-year follow-up. We allocated 95 patients randomly to receive a 4-week heliotherapy course, either at the onset or in the middle of the follow-up period. After a highly significant immediate alleviation of psoriasis about 50% of the patients still had a reduction of psoriasis 6 months later and ab ...
Pages: 388-392
Abstract  PDF
Is vitiligo an acquired pigmentary anomaly?
Salamon T.
Comment on Autotransplantation in vitiligo: treatment with epidermal grafts and cultured melanocytes. [Acta Derm Venereol. 1993]
Page: 393
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Psoriasis exacerbation induced by interferon-alpha. Report of two cases
Pauluzzi P, Kokelj F, Perkan V, Pozzato G, Moretti M.
No abstract available.
Page: 395
Abstract  PDF
Seborrheic dermatitis and daylight.
Verschoore M, Ortonne JP.
No abstract available.
Page: 396
Abstract  PDF