Content

Content - Volume 75, Issue 4

Editor's choice in this issue

All articles

INVESTIGATIVE REPORT
Three-dimensional architecture of human cutaneous vascular lesions: a scanning electron microscopic study of corrosion casts.
Arashiro K, Ohtsuka H, Miki Y
Corrosion casts were made from angiosarcoma of the scalp of an elderly person, Klippel-Trenaunay syndrome, pseudo-Kaposi's sarcoma, diffuse neonatal hemangiomatosis, cavernous hemangioma and arteriovenous malformation and were examined by scanning electron microscopy (SEM). The normal scalp from a cadaver was studied as a control for the angiosarcoma of the scalp. the SEM of the vascular corrosion ...
Pages: 257-263
Abstract  PDF
INVESTIGATIVE REPORT
Electronic infrared thermography as a method of assessing herpes labialis infection.
Biagioni PA, Lamey PJ
The purpose of this study was to ascertain the applicability of infrared thermography to study the natural history of herpes labialis lesions. Since thermography is capable of detecting changes not visible to the naked eye, then it may be of value in complementing clinical examination of the various stages of herpes labialis. In addition, thermographic imaging is quantitative and therefore allows ...
Pages: 264-268
Abstract  PDF
INVESTIGATIVE REPORT
Comparison of the effect of hydrocortisone, hydrocortisone-17-butyrate and betamethasone on collagen synthesis in human skin in vivo
Haapasaari KM, Risteli J, Koivukangas V, Oikarinen A
It has been shown previously that topical corticosteroid treatment decreases collagen synthesis in human skin in vivo and that the adverse effects are due to reduced collagen synthesis. The aim of the present study was to evaluate the effect of hydrocortisone, hydrocortisone-17-butyrate and betamethasone on collagen synthesis in human skin in vivo. Fourteen healthy male volunteers applied hydrocor ...
Pages: 269-271
Abstract  PDF
INVESTIGATIVE REPORT
Topical cis-urocanic acid suppresses both induction and elicitation of contact hypersensitivity in BALB/C mice
Lauerma AI, Aioi A, Maibach HI
Cis-urocanic acid, converted from trans-urocanic acid in stratum corneum by ultraviolet B irradiation, has been shown to impair contact hypersensitivity induction. To study whether topical cis-urocanic acid also alters contact hypersensitivity elicitation, as well as immediate hypersensitivity and acute irritation, we treated mice with 1% topical cis-urocanic acid or vehicle prior to induction or ...
Pages: 272-275
Abstract  PDF
INVESTIGATIVE REPORT
Influence of activation and differentiation of cells on the effectiveness of photodynamic therapy
Photodynamic therapy combines photosensitizers absorbing light in the red spectral region and irradiation with light of the corresponding wavelength. To analyse the influence of cell differentiation on susceptibility to photodynamic therapy, we compared the proliferation inhibition induced by photodynamic therapy on normal human keratinocytes, spontaneously transformed human keratinocyte cell line ...
Pages: 276-279
Abstract  PDF
The influence of the pH-value on the growth of Brevibacterium epidermidis in continuous culture
Lukacs A, Korting HC, Lemke O, Ruckdeschel G, Ehret W, Braun-Falco O.
Brevibacterium epidermidis is a major component of the bacterial flora of certain skin surface biotopes, characterized by a comparatively high pH-value. The presence of Brevibacterium epidermidis seems to be linked to the production of malodour. Skin surface pH has been found to be a major factor of bacterial growth on the skin. In order to find out if this might also apply to Brevibacterium epide ...
Pages: 280-282
Abstract  PDF
INVESTIGATIVE REPORT
Seasonal variation of tyrosinase activity in serum.
Sonesson B, Eide S, Rorsman H, Rosengren E
Serum samples for the analysis of tyrosinase activity were obtained from 10 healthy subjects in autumn, winter and summer. Tyrosinase was purified from 100 microl serum by adsorption to concanavalin A sepharose, the tyrosinase adsorbed to the gel being separated from other components by centrifugation. The gel was suspended in a buffer containing 5-hydroxy-indole-3-acetic acid as an antioxidant an ...
Pages: 283-286
Abstract  PDF
INVESTIGATIVE REPORT
Urinary excretion of melanocyte metabolites during treatment with chloroquine phosphate
Sjölin-Forsberg G, Hansson C, Kågedal B, Gannedahl EL, Berne B.
The antimalarial drug chloroquine is also used in the prevention of photodermatoses and in patients with inflammatory connective diseases. The drug binds strongly to melanin. Melanocytic activity can be studied by analysis of the urinary markers of eumelanin (6-hydroxy-5-methoxyindole-2-carboxylic acid, 6H5MI-2-C) and phaeomelanin (5-S-cysteinyl-dopa, 5-S-CD). To determine whether chloroquine inte ...
Pages: 287-289
Abstract  PDF
INVESTIGATIVE REPORT
Retinoids and fibrinolysis
Bäck O, Nilsson TK
Vitamin A and its analogues have been reported to increase the release of tissue plasminogen activator in vitro. The aim of the present study was to reevaluate these findings and to investigate whether retinoids in doses used in dermatological therapy could enhance the release of endothelial fibrinolytic factors. Our results showed that endothelial cells incubated in vitro with retinoic acid incre ...
Pages: 290-292
Abstract  PDF
INVESTIGATIVE REPORT
Raised serum androgens and increased responsiveness to luteinizing hormone in men with acne vulgaris
Ramsay B, Alaghband-Zadeh J, Carter G, Wheeler MJ, Cream JJ
We have investigated the hormone profiles and the relationship between serum testosterone and luteinizing hormone in men with long-standing acne vulgaris. In the controls, age correlated with the free androgen index and with serum dehydroepiandrosterone-sulphate, so for the purposes of comparison 33 men with acne vulgaris were age-matched against 33 controls. Compared with controls, the acne patie ...
Pages: 293-296
Abstract  PDF
INVESTIGATIVE REPORT
Adenosine deaminase in progressive systemic sclerosis
Meunier P, Filipe P, Emerit I, Freitas J, Guerra Rodrigo F, Manso C
The aim of the present study was to confirm the increase of adenosine deaminase (ADA) activity in progressive systemic sclerosis (PSS), described by Sasaki & Nakajima, and to compare plasma ADA activity of patients in different stages of the disease. Enzyme activity was measured with a colorimetric assay. The 48 patients were subdivided into 3 groups: subgroup 1 (n = 10), disease still limited to ...
Pages: 297-299
Abstract  PDF
CLINICAL REPORT
Occurrence and clinical features of sensitization to Pityrosporum orbiculare and other allergens in children with atopic dermatitis.
Lindgren L, Wahlgren CF, Johansson SG, Wiklund I, Nordvall SL
One hundred and nineteen consecutive cases of children with atopic dermatitis aged 4-16 years (73 girls) from a pediatric dermatology outpatient clinic were included in a study of atopic sensitization. Structured interviews and clinical investigations were performed. IgE antibodies to common inhalant allergens, Pityrosporum orbiculare, Candida albicans, Tricophyton rubrum and Staphylococcus aureus ...
Pages: 300-304
Abstract  PDF
CLINICAL REPORT
An epidemic of tinea corporis caused by Trichophyton tonsurans among wrestlers in Sweden.
Hradil E, Hersle K, Nordin P, Faergemann J.
An epidemic of tinea corporis due to Trichophyton tonsurans among wrestlers in Sweden is described. Totally 19 patients, 14 patients from Malmö and 5 from Gothenburg, were found. The suspected source of this epidemic was from a wrestlers' team from the USA visiting Sweden in April, 1993. All patients were treated orally with either griseofulvin, fluconazole or terbinafine, and all were cured. To ...
Pages: 305-306
Abstract  PDF
CLINICAL REPORT
Hyperpigmentation due to calcipotriol (MC 903) plus heliotherapy in psoriatic patients. Three case reports.
Kokelj F, Lavaroni G, Perkan V, Plozzer C
Calcipotriol is a synthetic analogue of vitamin D, used in the treatment of psoriasis. Until now no specific sid-effects have been described after combined therapy with calcipotriol and UV. We describe 3 patients, who in the summer of 1993, after a combined treatment of calcipotriol and heliotherapy, developed hyperpigmentation in the site where the ointment had been applied. Hyperpigmentation hea ...
Pages: 307-309
Abstract  PDF
CLINICAL REPORT
Mucocutaneous fungal colonization in HIV-infected children.
Don PC, Shen NN, Koestenblatt EK, Sierra MF, Stone RK, Bamji M
The prevalence of symptomatic mucocutaneous candidiasis in HIV-infected children is well documented. Information, however, of the carriage rate of potential fungal pathogens is lacking. In this study we determined the fungal colonization rate of multiple mucocutaneous sites from 13 HIV-infected and 12 control children. The rate of yeast and mould colonization and the species of fungal isolates wer ...
Pages: 310-311
Abstract  PDF
CLINICAL REPORT
HPV infection in male partners of women with squamous intraepithelial neoplasia and/or high-risk HPV
Strand A, Rylander E, Wilander E, Zehbe I
In order to estimate the prevalence of HPV infection in male partners of women with squamous intraepithelial lesions and/or high risk HPV, we examined 25 men. In situ hybridisation or polymerase chain reaction was used to detect HPV DNA in biopsied tissue or cell samples from the genital epithelium. Twenty (80%) of the male consorts had clinical features suggestive of HPV infection. Of these, 18 ( ...
Pages: 312-316
Abstract  PDF
LETTER TO THE EDITOR
Antibodies to the 90 kDa heat shock protein in chronic plaque psoriasis
al-Masaud AS, Wood EJ, Cunliffe WJ
Pages: 317-319
Abstract  PDF
LETTER TO THE EDITOR
Prostaglandin E1 improves necrobiosis lipoidica
Kuwert C, Abeck D, Steinkraus V, Jakob T, Ring J
Pages: 319-320
Abstract  PDF
LETTER TO THE EDITOR
Acquired multiple cavernous hemangiomas of the hand.
Takimoto R, Tsuboi R, Ogawa H
Pages: 321-322
Abstract  PDF
LETTER TO THE EDITOR
LEOPARD syndrome associated with steatocystoma multiplex and hyperelastic skin. Report of a Japanese case.
Mochizuki-Osawa M, Terui T, Kato T, Tagami H
Pages: 323-324
Abstract  PDF
LETTER TO THE EDITOR
Cyclosporin A in metastatic Crohn's disease.
Bardazzi F, Guidetti MS, Passarini B, Spettoli E
Pages: 324-325
Abstract  PDF
LETTER TO THE EDITOR
Multiloculated lentigo maligna melanoma in a patient without evidence for xeroderma pigmentosum.
Brandt O, Abeck D, Weichenthal M, Steinkraus V, Breitbart E, Jung EG, Ring J.
Pages: 326-327
Abstract  PDF
LETTER TO THE EDITOR
Erythema gyratum repens-like eruption in a patient with Sjögren syndrome.
Matsumura T, Kumakiri M, Sato-Matsumura KC, Ohkawara A.
Pages: 327-327
Abstract  PDF
LETTER TO THE EDITOR
Cutaneous alternariosis occurring in a patient treated with local intrarectal corticosteroids.
Machet L, Machet MC, Maillot F, Cotty F, Vaillant L, Lorette G
Pages: 328-329
Abstract  PDF
LETTER TO THE EDITOR
Very low-dose chloroquine treatment for porphyria cutanea tarda.
Drago F, Battifoglio ML, Gelati G, Rebora A
Pages: 329-330
Abstract  PDF
LETTER TO THE EDITOR
Could bacterial acetaldehyde production explain the deleterious effect of alcohol on skin diseases?
Höök-Nikanne J, Kariniemi AL, Renkonen OV, Mustakallio K, Salaspuro M
Pages: 330-330
Abstract  PDF
LETTER TO THE EDITOR
Diffuse palmoplantar keratoderma associated with acrocyanosis and livedo reticularis. Two sporadic cases.
Ohtake N, Sou K, Tsukamoto K, Furue M, Tamaki K
Pages: 331-331
Abstract  PDF