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Content - Volume 78, Issue 3

Editor's choice in this issue

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Restricted usage of the T-cell receptor Vß repertoire in tonsillitis in association with palmoplantar pustulosis: Investigative reports
Toshiyuki Yamamoto, Ichiro Katayama, Kiyoshi Nishioka
Focal infections such as chronic tonsillitis or dental caries occasionally play a role in the induction or exacerbation of palmoplantar pustulosis (PPP). Arthro-osteitis is sometimes a complication in severe cases of PPP. To study the effects of bacterial infection on the exacerbation of cutaneous lesions and arthralgia, we investigated the T-cell receptor Vβ repertoire in peripheral blood monon ...
Pages: 161-163
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Disruption of the Vertical Calcium Gradient in Murine Epidermis by a Potent Vitamin D3 Analogue, KH 1060
R. Gniadecki, J. Serup, B. Gajkowska
The hormonal forms of vitamin D3 (1,25-dihydroxyvitamin D3 and synthetic vitamin D3 analogues) are potent regulators of keratinocyte growth and stimulators of keratinocyte differentiation. Recent experiments in vitro on cultured keratinocytes indicate that Ca2+ may be a second messenger mediating the effects related to the induction of keratinocyte differentiation by the hormona ...
Pages: 164-168
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Comparative Study of the In vitro Inflammatory Activity of Three Nickel Salts on Keratinocytes
I. Sainte-Marie, O. Jumbou, I. Tenaud, B. Dreno
Nickel, the allergen of contact dermatitis, induces the in vitro production of inflammation markers such as intracellular adhesion molecule-1, interleukin-1 and tumour necrosis factor-α by keratinocytes. The purpose of our study was to compare the effect in vitro of different nickel salts on keratinocyte activation in order to determine whether this process depends on the nature of ...
Pages: 169-172
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Thomsen-Friedenreich and its precursor (Tn) antigen expression in normal skin and in benign cutaneous tumours: a marker for sebaceous differentiation
Jean Kanitakis, Issam Al-Rifai, Michel Faure, Alain Claudy
The Thomsen-Friedenreich (T) antigen is the core disaccharide of cancer-associated carbohydrates, whose expression allegedly correlates with the prognosis of some carcinomas. We studied the expression of the T antigen and its precursor (Tn) with monoclonal antibodies in formalin-fixed specimens of normal skin and various benign cutaneous tumours and inflammatory lesions (n: 105). In normal skin, ...
Pages: 173-176
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Early Detection of Epidermal Dust-like Particles in Experimentally UV-induced Lesions in Patients with Photosensitivity and Lupus Erythematosus
F. Nyberg, C. Skoglund, E. Stephansson
Dust-like particles, producing a specific fine-speckled, epidermo-subepidermal direct immunofluorescence staining pattern, have been associated mainly with subacute cutaneous lupus erythematosus (LE). Under experimental conditions the appearance of immunoglobulins along the basement membrane in ultraviolet (UV) light-induced lesions has been reported as a late phenomenon.
In this study, photo ...
Pages: 177-179
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A clinical and flow cytometric model to study remission and relapse in psoriasis
Conrad P. Glade, Piet E. J. Van Erp, Hildburg Werner-Schlenzka, Peter C. M. Van De Kerkhof
The aim of the present study has been to analyse remission and relapse characteristics in psoriasis vulgaris. In 15 patients, two different psoriatic lesions (clinical and flow cytometric study) were treated with clobetasol propionate until clearance for maximally 23 days. In the clinical study only cleared lesions were divided into three test sectors with different post-clearance treatment: (1) ...
Pages: 180-185
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Colorimetric Method for Quantifying Human Stratum Corneum Removed by Adhesive-Tape-Stripping
F. Dreher, A. Arens, J. J. Hostýnek, S. Mudumba, J. Ademola, H. I. Maibach
Tape-stripping of the skin is a useful method for removing the stratum corneum and obtaining more information about the function of this skin layer as the main barrier for skin penetration. The amount of stratum corneum removed is of relevance in establishing the concentration profile of chemicals within the stratum corneum after topical application. Weighing is the preferred ...
Pages: 186-189
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Studies on Mast Cells and Histamine Release in Psoriasis: The Effect of Ranitidine
Lars I. Petersen, Ulla Hansen, Johannes K. Kristensen, Henrik Nielsen, Per S. Skov, Hans J. Nielsen
The purpose of this study was to investigate histamine and skin mast cells in psoriasis before and during 6 months of treatment with high-dose ranitidine. Sixteen psoriasis patients, presenting a mean PASI score of 15.4, were compared with 13 age- and sex-matched healthy controls. Resting extracellular skin levels of histamine and histamine release to mast cell secretagogues, as measured by the m ...
Pages: 190-193
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Clinical reports: Antiinflammatory properties of cetirizine in a human contact dermatitis model: Clinical evaluation of patch tests is not hampered by antihistamines
Jean Jacques Grob, Michel Castelain, Marie Aleth Richard, Jean Pierre Bonniol, Valérie Beéraud, Hertzel Adhoute, Nadia Guillou, Jean Jacques Bonerandi
The aim of this double-blind, placebo-controlled, randomized, cross-over pilot study was to assess the antiinflammatory properties of cetirizine. A group of 27 patients with a positive patch test to an allergen consecutively received cetirizine 10 mg o.d. or placebo during a 14-day period, respectively. At day 11 of each period, patch testing was performed with the allergen. The image analysis sh ...
Pages: 194-197
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Cutaneous involvement as the first manifestation in a case of T-cell prolymphocytic leukaemia
Angèlica Serra, M. Teresa Estrach, Rosa Martí, Neus Villamor, Montserrat Rafel, Emili Montserrat
Mature T-cell malignancies of extracutaneous origin are rare disorders. T-cell prolymphocytic leukaemia (T-PLL) is the most common form of all mature T-cell leukaemias in adults. Secondary skin involvement by T-PLL has been reported in 25% of patients. A case of T-PLL which presented with cutaneous infiltration mimicking a cellulitis-like lesion resistant to antibiotic therapy is described. The d ...
Pages: 198-200
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Subbandage Pressure Measurements Comparing a Long-stretch with a Short-stretch Compression Bandage
Lis Danielsen, Søren Munk Madsen, Lene Henriksen, Jens Sindrup, Lars J. Petersen
Forty-three patients with venous leg ulcers were randomized into treatment with either a long- or a short-stretch compression bandage. Subbandage pressure was regularly measured during rest and walking for a period of up to 1 year. The long-stretch bandage was kept on as long as possible, often up to 1 week. It maintained a significantly higher subbandage pressure in the upright position and duri ...
Pages: 201-204
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Herpes Virus-like DNA (HHV-8) in Immunosuppressive Therapy-related, HIV-related and Classical Kaposi's Sarcoma in Norwegian Patients
Petter Jensen, Yao Qi Huang, Jian Jun Li, Ole Petter F. Clausen, Alvin E. Friedman-Kien
The recently discovered human herpes virus 8 (Kaposi's sarcoma-associated herpes virus) has been implicated in the pathogenesis of Kaposi's sarcoma. Using polymerase chain reaction we detected DNA sequences of this herpes virus in 11 of 14 biopsy specimens from Kaposi's sarcoma in Norwegian patients, including the immunosuppressive therapy-related type (3 of 3), the HIV-related type (4 of 5), and ...
Pages: 205-206
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Acrodermatitis Chronica Atrophicans: Histopathologic Findings and Clinical Correlations in 111 Cases
Eva Brehmer-Andersson, Anders Hovmark, Eva Åsbrink
We studied 111 consecutive, untreated and serologically confirmed patients with acrodermatitis chronica atrophicans. Emphasis was on the histopathologic patterns of erythematous and fibrous lesions, and on an assay used to correlate histopathologic findings with such clinical features as fibrous nodules, ulnar bands and the pain reaction allodynia. There was a significant correlation between allo ...
Pages: 207-213
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Interdependence of Eye and Hair Colour, Skin Type and Skin Pigmentation in a Caucasian Population
Jørgen Lock-Andersen, Hans Christian Wulf, Niels Ditlev Knudstorp
Eye colour, hair colour and skin colour are important risk factors for malignant melanoma and non-melanoma skin cancers. There are few studies in which the distribution of these pigmentary factors in risk populations has been assessed. The purpose of this study was to investigate the prevalence of the major eye and hair colours and the distribution of skin types and skin pigmentation in a Caucasi ...
Pages: 214-219
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Juvenile generalized pustular psoriasis: Letters to the editor
This article does not have an abstract.
Page: 220
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Acute generalized exanthematous pustulosis associated with paracetamol
This article does not have an abstract.
Pages: 222-223
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Acute generalized exanthematous pustulosis induced by amoxapine
This article does not have an abstract.
Page: 224
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Pitted keratolysis: a discussion of two cases in non-weight-bearing areas
This article does not have an abstract.
Pages: 225-226
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Somatostatin and psoriasis
This article does not have an abstract.
Page: 226
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Pemphigus foliaceus associated with cilazapril
This article does not have an abstract.
Page: 227
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Eruptive multiple keratoacanthomas of the extremities
This article does not have an abstract.
Pages: 228-229
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Scleroderma renal crisis in association with essential oils
This article does not have an abstract.
Page: 230
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Chronic cutaneous leishmaniasis mimicking sebopsoriasis
This article does not have an abstract.
Page: 231
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Dermatofibrosarcoma protuberans and basal cell carcinoma
This article does not have an abstract.
Page: 233
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Herpes Zoster
This article does not have an abstract.
Page: 234
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Response to the letter by Nikkels & Pi rard
This article does not have an abstract.
Pages: 234-235
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Focal Dermal Hypoplasia: A Case with Minor Clinical Manifestations
S. Menni, D. Boccardi and D. Imondi
Pages: 235-236
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Verrucous-crusted Herpes Zoster in an Immunocompetent Patient
S. Veraldi, L. Gnecchi and F. Zorzi
Pages: 236-237
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Erythema Annulare Centrifugum Associated with Pregnancy
Charoen Choonhakarn and Pitulak Seramethhakun
Pages: 237-238
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Becker's Naevus of the Lower Limb
Binod K. Khaitan, Devraj Dogra, Yashpal Manchanda and Sanjay Rathi
Pages: 238-239
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