Content - Volume 78, Issue 6

Editor's choice in this issue

All articles

Editorial: Thanks for the Years with Acta Dermato-Venereologica
Lennart Juhlin
This article does not have an abstract.
Page: 401
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Differential Epidermal Expression of the Invariant Chain in Allergic and Irritant Contact Dermatitis
Axel Emilson, Magnus Lindberg, Annika Scheynius
Allergic contact dermatitis and irritant contact dermatitis have different pathogenic mechanisms. It is therefore plausible that the epidermal expression of HLA-DR and the invariant chain associated with antigen processing and presentation might differ between allergic contact dermatitis and irritant contact dermatitis. We have quantified the volume of epidermal HLA-DR and invariant chain reactiv ...
Pages: 402-407
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Rhythmical Variations of Haemoglobin Oxygenation in Cutaneous Capillaries
Markus Stücker, Jana Steinbrügge, Christiane Ihrig, Klaus Hoffmann, Dieter Ihrig, Anja Röchling, Dietrich Lübbers, Holger Jungmann, Peter Altmeyer
The consequences of rhythmical arteriolar vasomotion for nutrition and the tissue oxygen supply to human skin are largely unknown. In the study presented here, the periodic variations of haemoglobin oxygenation in the small cutaneous vessels have been evaluated with a new reflection spectrophotometer. For the assessment of spatial variations, we examined 24 different sites in 20 healthy volunteer ...
Pages: 408-411
Abstract  PDF
Mutations in the 1A Rod Domain Segment of the Keratin 9 Gene in Epidermolytic Palmoplantar Keratoderma
Jun-Mo Yang, Seewoo Lee, Hyo-Jung Kang, Jeung-Hoon Lee, Un-Cheol Yeo, Il-Young Son, Ki-Beom Park, Peter Steinert, Eil-Soo Lee
Palmoplantar keratodermas (PPK) constitute a heterogeneous group of diseases marked by the thickening of palms and soles of affected individuals. They are divided into autosomal dominant and autosomal recessive groups by the mode of transmission. The autosomal dominantly transmitted group is further divided into epidermolytic (EPPK, Voerner) and non-epidermolytic (NEPPK, Unna-Thost) types accordi ...
Pages: 412-416
Abstract  PDF
A Glutamate to Lysine Mutation at the End of 2B Rod Domain of Keratin 2e Gene in Ichthyosis Bullosa of Siemens
Jun-Mo Yang, Eun-So Lee, Hyo-Jung Kang, Gwang-Seong Choi, Kozo Yoneda, Seung-Yong Jung, Ki-Beom Park, Peter Steinert, Eil-Soo Lee
Ichthyosis bullosa of Siemens is a rare autosomal dominant skin disorder whose clinical findings are quite similar to those of epidermolytic hyperkeratosis. The differences between those two diseases include absence of erythroderma and different distributions in the skin in ichthyosis bullosa of Siemens. Recent studies have confirmed that ichthyosis bullosa of Siemens is caused by the mutation in ...
Pages: 417-419
Abstract  PDF
Estrogenic Xenobiotics Increase Expression of SS-A/Ro Autoantigens in Cultured Human Epidermal Cells
Kou Sakabe, Takahiko Yoshida, Hiroyuki Furuya, Fujio Kayama, Edward K. L. Chan
SS-A/Ro autoantibodies are detected at high levels in patients with autoimmune diseases such as systemic lupus erythematosus. It has been reported that natural estrogen is capable of inducing cell surface expression of SS-A/Ro autoantigens in human epidermal keratinocytes. In this study, we analysed, by reverse transcriptase polymerase chain reaction and immunohistochemistry, the effects of estro ...
Pages: 420-423
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Expression of T Cell Receptor Vß Chain in Lesional Skin of Atopic Dermatitis
Seog-Jun Ha, Hyun-Jeong Lee, Dae-Gyoo Byun, Jin-Wou Kim
Atopic dermatitis is a chronic, relapsing inflammatory skin disorder characterized by local infiltration of T cells. To date, numerous reports have shown that Staphylococcus aureus may exacerbate atopic dermatitis, and superantigens produced by this organism are thought to be one of the major causative factors in atopic dermatitis. The purpose of this study was to evaluate the role of stap ...
Pages: 424-427
Abstract  PDF
Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In vitro and Convert Hair Cycle In vivo
Tomoya Takahashi, Toshikazu Kamiya, Yoshiharu Yokoo
For the purpose of discovering natural products which possess hair growing activity, we examined about 1000 kinds of plant extracts concerning growth-promoting activity with respect to hair follicle cells. After an extensive search, we discovered that proanthocyanidins extracted from grape seeds promote proliferation of hair follicle cells isolated from mice by about 230% relative to controls (10 ...
Pages: 428-432
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Murine Local Lymph Node Assay for Predictive Testing of Allergenicity: Two Irritants Caused Significant Proliferation
Johan Montelius, Helen Wahlkvist, Anders Boman, Jan Wahlberg
The murine local lymph node assay is a method for predictive testing of contact allergenicity, but its ability to discriminate between allergens and irritants has been questioned. To explain some of the conflicting results with irritants, the proliferation induced by methyl salicylate and nonanoic acid, both considered to be non-sensitisers, was further investigated. Both substances showed a dose ...
Pages: 433-437
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Pinch Grafting of Leg Ulcers in Primary Care
Rut F. Öien, Bjarne U. Hansen, Anders Håkansson
Treatment of chronic leg ulcers consumes considerable primary care resources. For the patient, it often entails restrictions in everyday life. This study describes the results of 84 skin transplantations on 45 patients with 55 ulcerated limbs, using the pinch graft technique, performed in primary care from 1987-1993. The healing rate after 12 weeks for venous ulcers was 45%, and for neuropathic u ...
Pages: 438-439
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Chronic Urticaria and Helicobacter pylori
Rossano Valsecchi, Paolo Pigatto
Chronic urticaria can result from multiple causes. A number of factors have been identified that can appear to be important in the pathogenesis of individual cases, including intolerance to food, drugs, some internal diseases and some infections. Recently a possible relationship between chronic urticaria and Helicobacter pylori has been suggested. One hundred and twenty-five patients were investi ...
Pages: 440-442
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Selective Photothermolysis of Hair Follicles by Normal-mode Ruby Laser Treatment
Thomas Walther, Wolfgang Bäumler, Matthias Wenig, Michael Landthaler, Ulrich Hohenleutner
This study was designed to evaluate the effect of selective photothermolysis on dark pigmented hair follicles treated with a normal-mode ruby laser (694-nm wavelength, pulse duration 0.5 ms, fluence 20 J/cm2, spot size 2 mm). In 15 volunteers, four test areas each were selected. After shaving, the first area was irradiated once, the second twice, the third three times and the fourth se ...
Pages: 443-444
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Side Effects from the Pulsed Dye Laser: The Importance of Skin Pigmentation and Skin Redness
Merete Haedersdal, Monika Gniadecka, Jan Efsen, Niels Bech-Thomsen, Jens Keiding, Hans Christian Wulf
The pulsed dye laser is the treatment of choice for port-wine stains. In this study we evaluate the importance of preoperative skin pigmentation and skin redness for the development of side effects from one treatment with the pulsed dye laser. A risk assessment is performed and skin reflectance measurement objectifies postoperative pigmentary changes. Fourteen human volunteers (skin types I to V) ...
Pages: 445-450
Abstract  PDF
The Development of an Acne Quality of Life Scale: Reliability, Validity, and Relation to Subjective Acne Severity in Mild to Moderate Acne Vulgaris
Madhulika A. Gupta, Andrew M. Johnson, Aditya K. Gupta
We developed a disease-specific 9-item Acne Quality of Life scale that is sensitive to changes in patient-rated indices of acne severity and the psychological morbidity that is associated with acne. Seventy patients with mild to moderate acne vulgaris completed a 12-item scale that was developed to assess both the social and vocational impacts of acne. Factor analysis revealed the presence of two ...
Pages: 451-456
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Cutaneous Sarcoidosis: Complete Remission after Oral Isotretinoin Therapy
S. Georgiou, A. Monastirli, E. Pasmatzi, D. Tsambaos
We report a 31-year-old female patient with cutaneous sarcoidosis, who showed a complete remission of her single system skin disease after an 8-month therapy with oral isotretinoin (1 mg/kg/day). At 15-month follow-up, the patient still remained free of recurrence and visceral involvement.
Pages: 457-459
Abstract  PDF
Syringoma: A Review of Twenty-nine Cases
A. Patrizi, I. Neri, S. Marzaduri, E. Varotti and B. Passariní
Pages: 460-462
Abstract  PDF
Subclinical Joint Involvement in Psoriasis: Magnetic Resonance Imaging and X-ray Findings
Annamaria Offidani, Andreina Cellini, Gianluca Valeri, Andrea Giovagnoni
Previous studies have shown that magnetic resonance imaging is more sensitive in assessing soft tissue and bone involvement in inflammatory arthritis than conventional radiography. Therefore the main objects of this study were to evaluate the frequency of hand involvement in psoriatic patients free from arthritic symptoms, and to compare the results with those of a healthy control population (age ...
Pages: 463-465
Abstract  PDF
Comparison of Actual Psoriasis Surface Area and the Psoriasis Area and Severity Index by the Human Eye and Machine Vision Methods in Following the Treatment of Psoriasis
L. Savolainen, J. Kontinen, E. Alatalo, J. Röning, A. Oikarinen
The lack of a quantitative method for assessing psoriasis severity poses a problem for quality control in dermatology. Quantitative estimation of involved surface area is important, as in the psoriasis area and severity index (PASI), but the reliability of many methods is poor. The purpose of this study was to assess the involved surface area of 15 psoriasis patients before and after different an ...
Pages: 466-467
Abstract  PDF
Acquired Malalignment: A Complication of Lateral Longitudinal Nail Biopsy
David A. R. de Berker, Robert Baran
We report the development of malalignment of the nail following lateral longitudinal biopsy of the nail unit in seven subjects. The lateral biopsies were in excess of the routine 3 mm diagnostic biopsy performed for investigation of a nail dystrophy, being indicated for excision of focal pathology. Deviation of the distal nail towards the side of excision might be accounted for by one or both of ...
Pages: 468-470
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Familial Leukonychia Totalis
Edouard Grosshans
This article does not have an abstract.
Page: 471
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Urticaria Due to Occupational Exposure to Glyceryl Monothioglycolate Permanent Wave Solution
Walter Shelley, Dorinda Shelley, Nickolai Talanin
This article does not have an abstract.
Pages: 471-472
Abstract  PDF
Angiokeratoma Circumscriptum of the Oral Cavity
M. Vijai Kumar, Devinder M. Thappa, Srikanth Shanmugam, Chaganti Ratnakar
This article does not have an abstract.
Page: 472
Abstract  PDF
Non-purulent Furunculoid Cutaneous Nodules as an Indicator for Agranulocytosis
M. Lüftl, Ch. Schöber, W. Ch. Marsch
This article does not have an abstract.
Pages: 473-474
Abstract  PDF
Trichilemmal Carcinoma In situ
Yuko Sasaki, Hiroshi Shimizu, Takeji Nishikawa
This article does not have an abstract.
Pages: 474-475
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A Case of Verrucous Epidermal Naevus Successfully Treated with Acitretin
Oktay Taykapan, Bilal Do<an, Hüseyin Balo<lu, Yavuz Harmanyeri
This article does not have an abstract.
Pages: 475-476
Abstract  PDF
A Case of Cat Scratch Disease Diagnosed by Serologic Tests Specific for Bartonella henselae
Tetsuya Koga, Yumiko Kubota, Shoji Toshitani
This article does not have an abstract.
Page: 477
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Congenital Onychodysplasia of the Index Fingers with Anomaly of the Great Toe
Hiroko Koizumi, Takako Tomoyori, Akira Ohkawara
This article does not have an abstract.
Pages: 478-479
Abstract  PDF
Isotretinoin for Sebaceous Skin Lesions in Muir-Torre Syndrome: A Case Report
Jan A. Marcusson, Bolli Bjarnason, A-M. Ros
This article does not have an abstract.
Pages: 479-480
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Response to the Letter by Professor Grosshans
Lars Detlev Köhler, Matthias Möhrenschlager, Johannes Ring
This article does not have an abstract.
Page: 481
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Angioedema Due to Chironoida Larvae Used as Fish Food
Francesco Purello D'Ambrosio, Luisa Ricciardi, Sebastiano Gangemi, Stefania Isola, Marcello Cilia, Carmelo Levanti
This article does not have an abstract.
Pages: 482-483
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On the Association Between Vitiligo and Malignant Melanoma
B. Lindelöf, M-A. Hedblad, B. Sigurgeirsson
This article does not have an abstract.
Pages: 483-484
Abstract  PDF
Non-AIDS-related Kaposi Sarcoma Tissues do not Contain DNA Sequences of HHV-6, HHV-7, Epstein-Barr Virus, Cytomegalovirus and HSV
Francesco Drago, Emilia Raineri, Alfredo Rebora
This article does not have an abstract.
Page: 485
Abstract  PDF