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Content - Volume 83, Issue 5

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In this issue…
Kristian Thestrup-Pedersen
This article does not have an abstract.
Page: 321
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LETTER TO THE EDITOR
Transgenic Mice Over-expressing a Serine Protease in the Skin: Evidence of Interferon ?-independent MHC II Expression by Epidermal Keratinocytes
Stratum corneum chymotryptic enzyme (SCCE; also known as kallikrein 7) is a serine protease that is preferentially expressed in cornifying epithelia and possibly involved in the desquamation process. We have recently described transgenic mice over-expressing human SCCE in the epidermis showing increased epidermal thickness, hyperkeratosis, and an apparent dermal inflammation with pruritus. This su ...
Pages: 322-327
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LETTER TO THE EDITOR
Allergy and Irritation: An Adverse Association in Patients with Atopic Eczema
The pathomechanism of atopic eczema is complex. Two of the most important exogenous factors for atopic eczema are allergenic and irritant substances. In this study we investigate the combined effect of topical aeroallergens and irritation on the skin of atopic individuals. We performed patch testing with several aeroallergens (atopy patch test) and with an irritant, sodium lauryl sulphate, on clin ...
Pages: 328-331
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LETTER TO THE EDITOR
Pathogenic Mechanisms in Epidermolysis Bullosa Naevi
Epidermolysis bullosa naevi are large, eruptive melanocytic naevi which frequently arise in areas of former blisters in patients suffering from inherited epidermolysis bullosa. Morphologically, these naevi are similar to malignant melanoma, although so far no malignant transformation has been observed. To investigate the pathogenesis of these moles we documented their clinical evolution and their ...
Pages: 332-337
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LETTER TO THE EDITOR
Influence of Climatic Conditions on the Irritant Patch Test with Sodium Lauryl Sulphate
Irritant patch testing with detergents is increasingly being used as a measure of skin barrier function, but there is evidence that climatic changes can influence the test outcome. In this study we investigated the relation between cutaneous reactivity to a detergent and climatic conditions. Between January 2000 and December 2001 epicutaneous patch testing with 0.5% sodium lauryl sulphate was perf ...
Pages: 338-341
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LETTER TO THE EDITOR
Lipid Peroxidation and Antioxidant Defence System in Patients with Active or Inactive Behçet's Disease
To evaluate plasma lipid peroxidation and enzymatic and non-enzymatic antioxidant systems in patients with Behçet's disease, plasma malondialdehyde levels and total antioxidant status, erythrocyte superoxide dismutase and whole blood glutathione peroxidase activities were studied in 15 patients with active disease and in 30 with inactive disease, and compared with 20 age-matched healthy control s ...
Pages: 342-346
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LETTER TO THE EDITOR
Atopic Dermatitis in Young Children: Diagnostic Criteria for Use in Epidemiological Studies Based on Telephone Interviews
The aim of the study was to establish diagnostic criteria for atopic dermatitis in 1.5-year-old children that could be employed in epidemiological studies of atopic dermatitis based on telephone interviews. In a Danish cohort of 100,000 pregnant women, 4 computer-assisted telephone interviews were carried out. In the last interview, conducted when the child was 1.5 years old, mothers were asked ab ...
Pages: 347-350
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LETTER TO THE EDITOR
An Experimental Ointment Formulation of Pimecrolimus is Effective in Psoriasis without Occlusion
Pimecrolimus (Elidel®, SDZ ASM 981), a new macrolactam ascomycin derivative, was highly effective in treating plaque-type psoriasis when applied under Finn-chamber occlusion. A two-centre, randomized, double-blind, vehicle- and positive-controlled within-patient study was therefore conducted in 23 adult psoriasis patients. Pimecrolimus 1% was applied, twice daily, in ...
Pages: 351-353
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LETTER TO THE EDITOR
Large B-cell Lymphoma of the Leg in a Patient with Multiple Malignant Tumours
A patient who had primary gastric B-cell non-Hodgkin's lymphoma, invasive ductal breast cancer and a basocellular carcinoma of the forehead in her medical history was studied. Three years after polychemotherapy and irradiation of the breast cancer, a rapidly enlarging, ulcerated violaceous tumour developed on the patient's left leg. The tumour was identified by the histopathological, immunohistoch ...
Pages: 354-357
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LETTER TO THE EDITOR
Papular Neutrophilic Dermatosis and Erythema Elevatum Diutinum Following Erythropoietin Therapy in a Patient with Myelodysplastic Syndrome
A 65-year-old man with refractory anaemia with an excess of blasts developed an erythematous papular eruption symmetrically distributed on the legs and trunk 3 months after initiation of erythropoietin therapy. The lesions showed a dense neutrophilic infiltrate in the absence of leucocytoclastic vasculitis, and did not fit the criteria of a well-defined neutrophilic dermatosis. Concomitant with th ...
Pages: 358-361
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LETTER TO THE EDITOR
Linear Scleroderma Along Blaschko's Lines in a Patient with Systematized Morphea
We have previously shown that frontoparietal scleroderma en coup de sabre, a type of linear scleroderma that affects the face and scalp, follows the lines of Blaschko, but the question whether linear scleroderma that occurs in the limbs follows Blaschko's lines has not been answered. We describe the case of a 4-year-old girl with multiple morphea showing remarkable unilateral systematized distribu ...
Pages: 362-364
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Short-time, High-dosage Penicillin Infusion Therapy of Syphilis: An Alternative to Recommended Regimens?
The optimal dosage and duration of penicillin treatment for the various stages of syphilis are not known. We present data on 20 patients with syphilis (primary, secondary or latent) treated with high-dose, short-time penicillin infusion therapy. Patients were given 10 MIU of penicillin G intravenously every 6 h up to a total dose of 90 MIU within 48 h. No adverse reactions were registered but 9 pa ...
Pages: 365-368
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Vulvar Vestibulitis: Evidence of Depression and State Anxiety in Patients and Partners
Vulvar vestibulitis is believed to be the most frequent cause of dyspareunia in premenopausal women, with the symptoms affecting the patient's life in several ways. We therefore assessed the level of depression and state anxiety in women with vulvar vestibulitis and their partners, and the association of depression and state anxiety with genital symptoms. In this prospective study, 30 women were i ...
Pages: 369-373
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Perianal Lentiginosis: A Case of Localized Lentiginosis
This article does not have an abstract.
Pages: 379-380
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A Curious Keloid of the Penis
This article does not have an abstract.
Pages: 384-385
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EDITORIAL COMMENT
Subcorneal Pustular Dermatosis and Mycoplasma pneumoniae Respiratory Infection
This article does not have an abstract.
Pages: 387-388
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Urticaria-Like Follicular Mucinosis Responding to Dapsone
This article does not have an abstract.
Pages: 389-390
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LETTER TO THE EDITOR
Disseminated Erythematous and Pityriasiform Plaques Caused by Imatinib Mesylate
This article does not have an abstract.
Pages: 391-392
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LETTER TO THE EDITOR
Two Cases of Henoch-Schönlein Purpura with Transient Myocardial Ischaemia
This article does not have an abstract.
Pages: 393-394
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LETTER TO THE EDITOR
Neutrophilic Eccrine Hidradenitis in a Patient with Behçet's Disease
This article does not have an abstract.
Pages: 395-396
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LETTER TO THE EDITOR
Malignant Melanoma Arising from a Small Congenital Melanocytic Naevus
This article does not have an abstract.
Pages: 397-398
Abstract  PDF