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Content - Volume 89, Issue 4

Editors choice in this issue

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REVIEW
Epidemiology of Itch: Adding to the Burden of Skin Morbidity
Elke Weisshaar, Florence Dalgard
Itch is the most frequent symptom in dermatology and has been researched more extensively in recent years. Nevertheless, there are few true epidemiological studies on itch. The aim of this paper is to review the current state of research on the epidemiology of chronic itch in Western and non-Western populations. The electronic databases PubMed, Medline and the Cochrane Library were searched. Confe ...
Pages: 339-350
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INVESTIGATIVE REPORT
Downregulation of SMAD2, 4 and 6 mRNA and TGFβ Receptor I mRNA in Lesional and Non-lesional Psoriatic Skin
Haiyan Yu, Ulrich Mrowietz and Oliver Seifert
Transforming growth factor beta (TGFβ) has been suggested to be an effective inhibitor of the increased keratinocyte proliferation in psoriasis. Three TGFβ isoforms are described (TGFβ1, 2 and 3), signalling via a heteromeric receptor complex of TGFβRI and TGFβRII. Receptor binding activates SMAD2, 3 and 4, which translocate into the nucleus and regulate TGFβ-responsive genes. SMAD6 and 7 pr ...
Pages: 351-356
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INVESTIGATIVE REPORT
Skin Pigmentation Kinetics after Exposure to Ultraviolet A
Mette H. Ravnbak, Peter A. Philipsen, Stine R. Wiegell and Hans C. Wulf
Multiple exposures to ultraviolet radiation (UVR) are the norm in nature and phototherapy. However, studies of the kinetics of pigmentation following UVA exposure have includ­ed only fair-skinned persons. The aim of this study was to investigate steady-state pigmentation and fading in 12 Scandinavians and 12 Indians/Pakistanis after 6 and 12 exposures on the back using broadband UVA and UVA1 wi ...
Pages: 357-363
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INVESTIGATIVE REPORT
Relevance of Psychosomatic Factors in Psoriasis: A Case-control Study
Slavenka Janković, Milena Raznatović, Jelena Marinković, Natasa Maksimović, Janko Janković and Bosiljka Djikanović
The aim of this study was to assess the role of stressful life events, lack of social support and attachment insecurity in triggering exacerbations of psoriasis. Outpatients experiencing exacerbation of psoriasis in the last 6 months (n = 110) were compared with outpatients affected by skin conditions in which psychosomatic factors are believed to play a minor role (n = 200). Stressful lif ...
Pages: 364-368
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INVESTIGATIVE REPORT
Factors Influencing the Clinical Evaluation of Facial Acne
Michel Faure, Henry Pawin, Florence Poli, Jean Revuz, Claire Beylot, Martine Chivot, Nicole Auffret, Dominique Moyse and Brigitte Dréno
Existing scoring systems for facial acne focus on the lesions themselves, but clinical decisions are based on a general assessment of severity, including the time since onset, the site(s) of involvement, the patient’s history, and the response to prior treatments. The aim of this study was to investigate the influence of some of these factors on the global assessment of acne severity. Involvemen ...
Pages: 369-371
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INVESTIGATIVE REPORT
Single Low-dose Red Light is as Efficacious as Methyl-aminolevulinate-photodynamic Therapy for Treatment of Acne: Clinical Assessment and Fluorescence Monitoring
Camilla Hörfelt, Bo Stenquist, Christina B. Halldin, Marica B. Ericson, and Ann-Marie Wennberg
This controlled study investigated single low-dose red light photodynamic therapy and methyl-aminolevulinate (MAL) for treatment of moderate to severe facial acne in 19 patients. The right cheek was treated with MAL (160 mg/g) for 3 h prior to illumination. The left cheek received red light only. Both cheeks were illuminated with narrow-band red light (635 nm) at a light dose of 15 J/cm2. The glob ...
Pages: 372-378
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CLINICAL REPORT
Clinical Aspects of Itch in Adult Atopic Dermatitis Patients
Danuta Chrostowska-Plak, Joanna Salomon, Adam Reich and Jacek C. Szepietowski
Although pruritus is an essential symptom of atopic dermatitis, its complex pathomechanism is not fully understood. The aim of this study was to characterize the clinical pattern of itch in adult subjects with atopic dermatitis. A total of 89 patients (59 females, 30 males) with atopic dermatitis, age range 18–60 years, were included in the study. Each patient completed a questionnaire about cli ...
Pages: 379-383
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CLINICAL REPORT
Characteristics of Nickel-allergic Dermatitis Patients Seen in Private Dermatology Clinics in Denmark: a Questionnaire Study
Jacob Pontoppidan Thyssen, Marianne Hald, Christian Avnstorp, Niels Kren Veien, Grete Lauerberg, Niels Henrik Nielsen, Knud Kaaber, Berit Kristensen, Ove Kristensen, Jens Thormann, Susanne Vissing, Torkil Menné and Jeanne Duus Johansen
The use of nickel in certain consumer goods has been regulated in Denmark since 1990. The aim of this study was to reveal the clinical characteristics of nickel-allergic patients seen in seven private dermatology clinics and to identify current sources of nickel that may elicit nickel dermatitis. During 2006 to 2007, 634 patients with dermatitis aged 17–91 years were patch-tested and completed a ...
Pages: 384-388
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CLINICAL REPORT
Chronic Urticaria is Usually Associated with Fibromyalgia Syndrome
Claudio Torresani, Salvatore Bellafiore and Giuseppe De Panfilis
Although the pathophysiology of chronic urticaria is not fully understood, it is possible that dysfunctioning of peripheral cutaneous nerve fibres may be involved. It has also been suggested that fibromyalgia syndrome, a multi-symptomatic chronic pain condition, may be associated with alterations and dysfunctioning of peripheral cutaneous nerve fibres. The aim of this study was to determine whethe ...
Pages: 389-392
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CLINICAL REPORT
Antiviral Therapy in Children with Hydroa Vacciniforme
Josefin Lysell, Desiree Wiegleb Edström, Annika Linde, Göran Carlsson, Johan Malmros-Svennilson, Anders Westermark, Jan Andersson and Carl-Fredrik Wahlgren
Hydroa vacciniforme is a rare, usually quite severe, photo­dermatosis. Association with Epstein-Barr virus infection and a possibly increased risk of lymphoprolifera­tive malignancy have been demonstrated. We describe here four patients with Epstein-Barr virus-associated hydroa vacciniforme treated with acyclovir/valacyclovir therapy with a good clinical response. The children were reported to ...
Pages: 393-397
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CLINICAL REPORT
Digital Gangrene in Systemic Lupus Erythematosus
Yayoi Nagai, Akira Shimizu, Mariko Suto, Setsuko Tanaka, Masahito Yasuda, Osamu Tago, Michiko Hasegawa and Osamu Ishikawa
Digital ulcers and gangrene are common skin manifestations of connective tissue diseases, especially systemic sclerosis, although they are relatively rare in systemic lupus erythematosus. We describe here three patients with digital gangrene and systemic lupus erythematosus. None of the patients showed high disease activity of systemic lupus erythematosus at the time the digital gangrene developed ...
Pages: 398-401
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CLINICAL REPORT
Simultaneous Onset of Segmental Vitiligo and a Halo Surrounding a Congenital Melanocytic Naevus
Uta B. Hofmann, Eva-Bettina Bröcker and Henning Hamm
Unlike in common melanocytic naevi, an acquired leukoderma (halo) surrounding a congenital melanocytic naevus is a rare phenomenon. A 6-year-old boy developed a depigmentation around a congenital melanocytic naevus on the right thigh. Simultaneously, segmental vitiligo appeared on the thigh, lower abdomen and buttock of the same side with sharp midline demarcation. Examination for associated autoi ...
Pages: 402-406
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LETTER TO THE EDITOR
Fatal Case of Darier’s Disease with Recurrent Severe Infections
Etsuko Okada, Yayoi Nagai, Sei-ichiro Motegi, Atsushi Tamura, Osamu Ishikawa
Abstract is missing (Letter)
Pages: 408-409
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LETTER TO THE EDITOR
Localized Abdominal Wall Bile Staining Due To Retroperitoneal Bile Leak
Francisco Allegue, Lidia Pérez-Pérez, María Teresa Maza, José Antonio Hermo and Ander Zulaica
Abstract is missing (Letter)
Pages: 410-411
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LETTER TO THE EDITOR
Urticaria Associated with Hyper-IgE in a Patient with Psoriasis Undergoing Treatment with Efalizumab
Rosita Saraceno, Gea Scotto, Andrea Chiricozzi and Sergio Chimenti
Abstract is missing (Letter)
Pages: 412-413
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LETTER TO THE EDITOR
Cutis Verticis Gyrata in a Patient with Hyper-IgE Syndrome
Hei Sung Kim, Rachael Yu Lin Teo and Audrey Wei-Hsia Tan
Abstract is missing (Letter)
Pages: 413-415
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LETTER TO THE EDITOR
Acquired Dermal Melanocytosis Naevus of Ota-like Macules on the Face and Extremities Lesions in a Young Japanese Woman
Tamihiro Kawakami, Chihiro Saito and Yoshinao Soma
Abstract is missing (Letter)
Pages: 415-416
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LETTER TO THE EDITOR
Successful Hair Re-growth with Multimodal Treatment of Early Cicatricial Alopecia in Discoid Lupus Erythematosus
Tatyana Hamilton, Nina Otberg, Wen-Yu Wu, Magdalena Martinka and Jerry Shapiro
Abstract is missing (Letter)
Pages: 417-418
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LETTER TO THE EDITOR
Bullous Pemphigoid with Localized Umbilical Involvement
Enno Schmidt, Sandrine Benoit and Eva-Bettina Bröcker
Abstract is missing (Letter)
Pages: 419-420
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LETTER TO THE EDITOR
Mycosis Fungoides with Recurrent Hodgkin’s Lymphoma and Diffuse Large B-cell Lymphoma
Tomomitsu Miyagaki, Makoto Sugaya, Yosaku Minatani, Hideki Fujita, Akira Hangaishi, Mineo Kurokawa, Yutaka Takazawa and Kunihiko Tamaki
Abstract is missing (Letter)
Pages: 421-422
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LETTER TO THE EDITOR
Folliculotropic Mycosis Fungoides with Severe Hepatic Failure due to Hepatic Involvement
Sayaka Shibata, Makoto Sugaya, Yousaku Minatani, Hideki Fujita, Yuichiro Tsunemi, Tomomitsu Miyagaki, Hidehisa Saeki, Kanako Kikuchi, Takashi Asai, Mineo Kurokawa and Kunihiko Tamaki
Abstract is missing (Letter)
Pages: 423-424
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LETTER TO THE EDITOR
Intravascular Large B-cell Lymphoma: Successful Therapy with Bendamustine and Rituximab
Anna Mleczko, Ingolf Franke, Karin Scheinpflug, Harald Gollnick and Martin Leverkus
Abstract is missing (Letter)
Pages: 425-427
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LETTER TO THE EDITOR
Thoracic Subcutaneous Infiltration: An Unusual Presentation of Subcutaneous Panniculitis-like T-cell Lymphoma
Fabienne Ballanger, Sébastien Barbarot, Steven Le Gouill, Fanny Gaillard, Elisabeth Cassagnau, Laurence Lodé, Brigitte Dréno and Jean F. Stalder
Abstract is missing (Letter)
Pages: 427-429
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LETTER TO THE EDITOR
Atypical Presentation and Dermoscopic Evaluation of Cutaneous Rosai-Dorfman Disease
Isabel Rodríguez-Blanco, José Manuel Suárez-Peñaranda, Jaime Toribio
Abstract is missing (Letter)
Pages: 430-431
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LETTER TO THE EDITOR
Pseudolymphomatoid Cutaneous Leishmaniasis in a Patient Treated with Adalimumab for Rheumatoid Arthritis
Susana Baltà-Cruz, Mercé Alsina-Gibert, Ana Mozos-Rocafort, Carlos Cervera, Lluís Colomo-Saperas, Ana Del Río and Teresa Estrach-Panella
Abstract is missing (Letter)
Pages: 432-433
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LETTER TO THE EDITOR
Cutaneous Necrosis Secondary to Terlipressin Therapy
Celia Posada, Carlos Feal, Arunzazu García-Cruz, Victoria Álvarez, Monica Álvarez and Manuel J. Cruces
Abstract is missing (Letter)
Pages: 434-435
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LETTER TO THE EDITOR
Malignant Acanthosis Nigricans with Enhanced Expression of Fibroblast Growth Factor Receptor 3
Yasutoshi Hida, Yoshiaki Kubo, Yukiko Nishio, Shinji Murakami, Daisuke Fukumoto, Koji Sayama, Koji Hashimoto and Seiji Arase
Abstract is missing (Letter)
Pages: 435-437
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LETTER TO THE EDITOR
Spontaneous Regression and Recurrence in a Case of Nodular Fasciitis
Eva N. Hüter, Chyi-Chia R. Lee, Richard M. Sherry and Mark C. Udey
Abstract is missing (Letter)
Pages: 438-439
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LETTER TO THE EDITOR
Benign Symmetric Lipomatosis Associated with Atopic Dermatitis and Chronic Alcohol Abuse in a Japanese Man
Tamihiro Kawakami, Sora Takeuchi and Yoshinao Soma
Abstract is missing (Letter)
Pages: 440-441
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LETTER TO THE EDITOR
A Case of Cutaneous Polyarteritis Nodosa in Autoimmune Hepatitis
Woo Jin Lee, Chae Hwa Kim, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Kee Chan Moon, Jai Kyoung Koh
This article does not have an abstract.
Pages: 442-443
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QUIZ
Progressive Refractory Ulcer of the Nipple: A Quiz
Yukiko Nomura, Masashi Akiyama, Wataru Nishie and Hiroshi Shimizu
Abstract is missing (Quiz)
Pages: 445-447
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QUIZ
Pigmented Lesion on the Cheek: A Quiz
Inés Zaraa, Anis Dammak, Hela Tounsi, Meriem Amouri, Mourad Mouaffek, Mourd Mokni, Samir Boubaker and Amel Ben Osman
Abstract is missing (Quiz)
Pages: 445-447
Abstract  HTML  PDF