Content

Content - Volume 90, Issue 4

Editor's choice in this issue

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EDITORIAL
In This Issue: To Expose or Not to Expose?
Jonathan Rees and Lisa Naysmith
One of us, when a trainee, was mildly admonished for returning from vacation with a moderate tan. The implicit message was that sun exposure was harmful and tanned dermatologists bad role models. Much as a respiratory physician who smoked set a bad example, so did a tanned dermatologist. Whatever the ethical or professional foundations for this view, the science underpinning this conceit was alway ...
Pages: 339-339
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IN THIS ISSUE
The Impact Factor Leaps Again!
Anders Vahlquist, Torbjörn Egelrud, Agneta Andersson
We are very pleased to inform our readers that Acta Dermato-Venereologica is thriving. We receive more and more articles for consideration. Probably as a result of the rising impact factor (Fig. 1) the number of submissions per year has now risen from 300 (2008) to presently almost 600. Concurrently the number of published pages has increased somewhat but not to the same extent, meaning that the a ...
Pages: 340-340
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REVIEW
Systemic Combination Treatment for Psoriasis: A Review
Peter Jensen, Lone Skov, Claus Zachariae
Psoriasis is a chronic inflammatory skin disease, which affects approximately 2.6% of the population in Northern Europe and Scandinavia. In order to achieve disease control, combinations of systemic treatments are sometimes needed for variable time periods. However, no evidence-based guidelines exist for the use of systemic combination therapy. Therefore, our aim was to review the current literatu ...
Pages: 341-349
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INVESTIGATIVE REPORT
Ceramides and Barrier Function in Healthy Skin
Jakob Mutanu Jungersted, Lars I. Hellgren, Julie K. Høgh, Tue Drachmann, Gregor B.E. Jemec, Tove Agner
Lipids in the stratum corneum are key components in the barrier function of the skin. Changes in lipid composition related to eczematous diseases are well known, but limited data are available on variations within healthy skin. The objective of the present study was to compare ceramide subgroups and ceramide/cholesterol ratios in young, old, male and female healthy skin. A total of 55 participants ...
Pages: 350-353
Abstract  PDF
INVESTIGATIVE REPORT
Effect of Itch, Scratching and Mental Stress on Autonomic Nervous System Function in Atopic Dermatitis
Bryant W. Tran, Alexandru D.P. Papoiu, Carmen V. Russoniello, Hui Wang, Tejesh J. Patel, Yiong-Huak Chan, Gil Yosipovitch
Atopic dermatitis is a stress-responsive disorder that involves the autonomic nervous system. The current study used heart rate variability to examine the effect of itch, scratching and mental stress in atopic patients with mod­erate to severe disease. Twenty-one patients with active disease and 24 healthy volunteers participated in the study. Heart rate variability measurements were taken at 5 m ...
Pages: 354-361
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INVESTIGATIVE REPORT
Non-melanoma Skin Cancer and Ten-year All-cause Mortality: A Population-based Cohort Study
Annette Østergaard Jensen, Anna Lei Lamberg, Jacob Bonde Jacobsen, Anne Braae Olesen, Henrik Toft Sørensen
Confounding from comorbidity and socioeconomic status may have biased earlier findings of all-cause mortality among patients with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We therefore examined all-cause mortality among 72,295 Danish patients with BCC, 11,601 with SCC, and 383,714 age- and gender-matched population control cohort subjects with extensive control for comorbidity ...
Pages: 362-367
Abstract  PDF
INVESTIGATIVE REPORT
Variation in Epidermal Morphology in Human Skin at Different Body Sites as Measured by Reflectance Confocal Microscopy
Karen Robertson, Jonathan L. Rees
Two methods of estimating stratum corneum thickness using reflectance confocal microscopy were examined, and epidermal thickness measurements at multiple body sites were compared. Measurements of stratum corneum thickness were made using the derivative method, which is based on the rate of change of image intensity as a proxy for keratin concentration, and simple visual analysis of confocal images ...
Pages: 368-373
Abstract  PDF
INVESTIGATIVE REPORT
Ethosome Formulations of Known Contact Allergens can Increase their Sensitizing Capacity
Jacob Torp Madsen, Stefan Vogel, Ann-Therese Karlberg, Carl Simonsson, Jeanne Duus Johansen, Klaus E. Andersen
Vesicular systems, such as liposomes and ethosomes, are used in cosmetic and pharmaceutical products to encapsulate ingredients, to protect ingredients from degradation, to increase bioavailability, and to improve cosmetic performance. Some reports have suggested that formulation of cosmetic ingredients in vesicular carrier systems may increase their contact allergy elicitation potential in humans ...
Pages: 374-378
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INVESTIGATIVE REPORT
Differences in the Peritumoural Inflammatory Skin Infiltrate Between Squamous Cell Carcinomas in Organ Transplant Recipients and Immunocompetent Patients
Britta Krynitz, Barbro Lundh Rozell, Bernt Lindelöf
Organ transplant recipients (OTR) have a greatly increased risk (up to 100 times) of developing squamous cell carcinomas (SCC) in the skin. This is attributed specifically to chronic immunosuppression, causing dysfunctional viral defence and tumour protection. To investigate the possible link between increasing risk of SCCs and type of inflammation in these tumour-prone patients, we analysed the p ...
Pages: 379-385
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INVESTIGATIVE REPORT
A Database Analysis of Cutaneous Lupus Erythematosus with the EUSCLE Core Set Questionnaire
Anna Maria Meuth, Suzanne Amler, Merle Haust, Dennis Bein, Cristina Sauerland, Wolfgang Köpcke, Gisela Bonsmann, Filippa Nyberg, Annegret Kuhn
The aim of this study was to determine whether the Core Set Questionnaire developed recently by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) is a useful tool to evaluate clinical features and therapeutic strategies in cutaneous lupus erythematosus. Disease characteristics were analysed in 50 patients with different subtypes of cutaneous lupus erythematosus from two European centr ...
Pages: 386-394
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CLINICAL REPORT
Somatic and Psychiatric Comorbidity in Patients with Chronic Pruritus
Ingela Ferm, Magnus Sterner, Joanna Wallengren
It has been reported that 10–50% of patients with pruritus but no skin rash have an underlying systemic disease and up to 70% a psychiatric one. The aim of this retrospective study was to review the records of a large number of patients with chronic pruritus for concomitant diseases and treatment options. Medical records of 139 patients (52 males, 87 females) with chronic pruritus who visited th ...
Pages: 395-400
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CLINICAL REPORT
Correlation of Immunological Profile with Phenotype and Disease Outcome in Pemphigus
Josep E. Herrero-González, Pilar Iranzo, Daniel Benítez, Francisco Lozano, Carmen Herrero, José M. Mascaro
There has been no previous clinical-immunological study of pemphigus in Spain. The aim of this study was to perform a retrospective analysis of pemphigus patients who had been followed for a period of 18 years in our centre. We characterized the autoantibody response, compared diagnostic assays and correlated the immunobiological data with phenotype and prognosis. Clinical, epidemiological and imm ...
Pages: 401-405
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CLINICAL REPORT
Ultrastructural Demonstration of a Relationship between Acquired Cutis Laxa and Monoclonal Gammopathy
Annabel Maruani, Brigitte Arbeille, Marie-Christine Machet, Christelle Barbet, Boris Laure, Ludovic Martin, Laurent Machet
Acquired cutis laxa is an uncommon disorder sometimes associated with monoclonal gammopathy and multiple myeloma, although the mechanism of this link is unclear. We report here a case of a 34-year-old man with generalized acquired cutis laxa and monoclonal light chain disease with renal and neurological involvement. Electron microscopy examination of a skin sample revealed shortened and fragmented ...
Pages: 406-408
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LETTER TO THE EDITOR
Treatment of Extrafacial Rosacea with Low-dose Isotretinoin
Öznur Bostanci, Claudia Borelli, Martin Schaller
Abstract is missing (letter)
Pages: 409-410
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LETTER TO THE EDITOR
Simvastatin in Psoriasis: Ambiguous Effects
Andreas Colsman, Michael Sticherling
Abstract is missing (letter)
Pages: 411-411
Abstract  PDF
LETTER TO THE EDITOR
Dermochondrocorneal Dystrophy (Francois’ Syndrome)
Jane Baumgartner-Nielsen, Jesper Hjortdal, Karsten Fogh
Abstract is missing (Letter)
Pages: 412-413
Abstract  PDF
LETTER TO THE EDITOR
Aspirin-intolerant Chronic Urticaria Exacerbated by Cutaneous Application of a Ketoprofen Poultice
Atsushi Fukunaga, Mayumi Hatakeyama, Kumiko Taguchi, Hideki Shimizu, Tatsuya Horikawa, Chikako Nishigori
Abstract is missing (Letter)
Pages: 413-415
Abstract  PDF
LETTER TO THE EDITOR
Solitary Glomus Tumour on the Nostril of a Child: Unusual Clinical Presentation
Yosuke Ishitsuka, Kuniaki Ohara, Fujio Otsuka
Abstract is missing (letter)
Pages: 415-416
Abstract  PDF
LETTER TO THE EDITOR
Imiquimod for the Treatment of Classical Kaposi's Sarcoma
Bianca Bernardini, Diana Faggion, Luisella Calabrò, Elisabetta Oro, Mauro Alaibac
Abstract is missing (Letter)
Pages: 417-418
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LETTER TO THE EDITOR
Cutaneous Lymphoid Hyperplasia Associated with Leishmania panamensis Infection
Sebastiano Recalcati, Pamela Vezzoli, Valentina Girgenti, Luigia Venegoni, Stefano Veraldi, Emilio Berti
Abstract is missing (letter)
Pages: 418-419
Abstract  PDF
LETTER TO THE EDITOR
A Case of Primary Idiopathic Cutaneous Pustular Vasculitis
Yoshihide Asano, Kenzo Kaji, Takeo Idezuki, Atsuyuki Igarashi
Abstract is missing (Letter)
Pages: 420-421
Abstract  PDF
LETTER TO THE EDITOR
Leukaemia Cutis at the Site of Striae Distensae: An Isotopic Response?
Chuan-I Liu, Che-Hao Hsu
Abstract is missing (Letter)
Pages: 422-423
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LETTER TO THE EDITOR
Painful Buruli Ulcer in a Malian Visitor to France
Khaled Ezzedine, Thierry Pistone, Veronique Guir, Denis Malvy
Abstract is missing (Letter)
Pages: 424-424
Abstract  PDF
LETTER TO THE EDITOR
Refractory Chronic Urticaria Treated Effectively with the Protease Inhibitors, Nafamostat Mesilate and Camostat Mesilate
Shunsuke Takahagi, Hajime Shindo, Makiko Watanabe, Yoshikazu Kameyoshi, Michihiro Hide
Abstract is missing (Letter)
Pages: 425-426
Abstract  PDF
LETTER TO THE EDITOR
Bullous Amyloidosis Mimicking Bullous Pemphigoid: Usefulness of Electron Microscopic Examination
Akihiko Asahina, Kazuko Hasegawa, Miyako Ishiyama, Tomomitsu Miyagaki, Yayoi Tada, Yuko Suzuki, Toshihide Kanabe, Ikuo Saito
Abstract is missing (Letter)
Pages: 427-428
Abstract  PDF
LETTER TO THE EDITOR
Possible Acceleration of Regression by Antibiotic Treatment in Benign Cephalic Histiocytosis with Infiltration of CD11a/CD11c+ Macrophages
Sven R. Quist, Heike Weidling, Ingolf Franke, Bernd Bonnekoh, Harald P. Gollnick
Abstract is missing (Letter)
Pages: 429-430
Abstract  PDF
LETTER TO THE EDITOR
Necrotizing Soft Tissue Infection of the Glans Penis due to Atypical Candida Species Complicated with Fournier’s Gangrene
Peter Jensen, Claus Zachariae, Frederik Grønhøj Larsen
Abstract is missing (letter)
Pages: 431-432
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LETTER TO THE EDITOR
Skin Necrosis Revealing Antiphospholipid Syndrome During Immunotherapy for Melanoma
Ludivine Gressier, Philippe Guilpain, Isabelle Gorin, Agnès Carlotti, Claire Goulvestre, Françoise Boitier, Loïc Guillevin, Marie-Françoise Avril, Luc Mouthon, Nicolas Dupin
Abstract is missing (letter)
Pages: 433-434
Abstract  PDF
LETTER TO THE EDITOR
Trichoblastoma-Like Tumour with Follicular, Matrical and Sebaceous Differentiation: Involvement of Hair Follicle Stem Cells?
Stephen Chu-Sung Hu, Chi-Ling Lin, Kun-Bow Tsai, Gwo-Shing Chen, Yi-Ying Chin, Chien-Te Lin, Cheng-Che E. Lan
Abstract is missing (letter)
Pages: 436-437
Abstract  PDF
LETTER TO THE EDITOR
CK7+/CK20– Merkel Cell Carcinoma Presenting as Inguinal Subcutaneous Nodules with Subsequent Epidermotropic Metastasis
Yen-Yun Tsai, Cheng-Hsiang Hsiao, Hsien-Ching Chiu, Ming Chen, Tsen-Fang Tsai
Abstract is missing (letter)
Pages: 438-439
Abstract  PDF
LETTER TO THE EDITOR
Diagnostic Pitfalls of Using Dermoscopic Features to Differentiate Between Malignant Melanoma and Pigmented Seborrhoeic Keratosis
Satoru Aoyagi, Hiroo Hata, Kentaro Izumi, Maria Maroto Iitani, Hiroshi Shimizu
Abstract is missing (letter)
Pages: 440-441
Abstract  PDF
LETTER TO THE EDITOR
Procalcitonin as a Biomarker for Toxic Shock Syndrome
Madoka Kato, Sakae Kaneko, Kenji Takagaki, Yoshitaka Kohayagawa, Tessin Watanabe, Yuichi Yoshida, Osamu Yamamoto
Abstract is missing (Letter)
Pages: 441-443
Abstract  PDF
LETTER TO THE EDITOR
Two Cases of Severe Refractory Chronic Idiopathic Urticaria Treated with Omalizumab
Christian Vestergaard, Mette Deleuran
Abstract is missing (letter)
Pages: 443-444
Abstract  PDF
LETTER TO THE EDITOR
White Papules Around the Ears: A Quiz
Sven R. Quist, Ingolf Franke, Bernd Bonnekoh, Harald Gollnick
Abstract is missing (Quiz)
Pages: 445-447
Abstract  PDF
LETTER TO THE EDITOR
Cystic Nodules Affecting Sexual Activity: A Quiz
Aleksandra Batycka-Baran, Wojciech Baran, Joanna Maj, Jacek C. Szepietowski
Abstract is missing (Quiz)
Pages: 445-447
Abstract  PDF