Content

Content - Volume 96, Issue 3

Editor's choice in this issue

INVESTIGATIVE REPORT
Pathophysiological Study of Sensitive Skin
Virginie Buhé, Katell Vié, Christelle Guéré, Audrey Natalizio, Céline Lhéritier, Christelle Le Gall-Ianotto, Flavien Huet, Matthieu Talagas, Nicolas Lebonvallet , Pascale Marcorelles , Jean-Luc Carré, Laurent Misery
Sensitive skin is a clinical syndrome characterized by the occurrence of unpleasant sensations, such as pruritus, burning or pain, in response to various factors, including skincare products, water, cold, heat, or other physical and/or chemical factors. Although these symptoms suggest inflammation and the activation of peripheral innervation, the pathophysiogeny of sensitive skin remains unknown. ...
Pages: 314-318
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CLINICAL REPORT
Patient Preferences for Treatment of Basal Cell Carcinoma: Importance of Cure and Cosmetic Outcome
Isabelle Martin, Marthe-Lisa Schaarschmidt, Anne Glocker, Raphael Herr, Astrid Schmieder, Sergij Goerdt, Wiebke K. Peitsch
Treatment options for localized resectable basal cell carcinoma (BCC) include micrographically controlled surgery, simple excision, curettage, laser ablation, cryosurgery, imiquimod, 5-fluorouracil, photodynamic therapy and radiotherapy. The aim of this study was to assess the preferences of patients with BCC for outcome (cure and recurrence rate, cosmetic outcome, risk of temporary and permanent ...
Pages: 355-360
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SHORT COMMUNICATION
Diagnosis of Amelanotic Lentigo Maligna by Using In vivo Reflectance Confocal Microscopy
Angela Alani, Bart Ramsay, Kashif Ahmad
Abstract is missing (Short communication)
Pages: 406-407
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All articles

IN THIS ISSUE
A New Perspective on the Formation of Stratum Corneum Intercellular Space
Magnus Lindberg
Abstract is missing (In this Issue...)
Page: 291
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COMMENTARY
Is Oil a Balsam for Baby Skin?
Lars Norlén
Abstract is missing (Commentary)
Page: 291
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REVIEW
Diagnosis of Mastocytosis in Children and Adults in Daily Clinical Practice
Magdalena Lange, Hanna Ługowska-Umer , Marek Niedoszytko, Bartosz Wasąg, Janusz Limon, Anton Żawrocki, Bogusław Nedoszytko, Michał Sobjanek, Katarzyna Plata-Nazar, Roman Nowicki
Mastocytosis comprises a heterogeneous group of disorders characterized by clonal, neoplastic proliferation of mast cells accumulating in one or multiple organs. In the majority of cases skin involvement is the first clinical manifestation of the disease. Clinical work-up consists of a combination of morphological, immunohistochemical, flow cytometric immunophenotyping and molecular examination. C ...
Pages: 292-297
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REVIEW
Delusional Infestation and Chronic Pruritus: A Review
Lynn S. Kimsey
The literature on chronic pruritus, paresthesia and delusional infestation indicates that a wide variety of conditions ranging from AIDS to vitamin deficiencies may cause these symptoms. In many, or perhaps most of these cases, activation of itch pathways seems to be the underlying cause of the skin sensations and perhaps even the visual hallucinations characteristic of delusional infestation. The ...
Pages: 298-302
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INVESTIGATIVE REPORT
Skin Lamellar Bodies are not Discrete Vesicles but Part of a Tubuloreticular Network
Lianne den Hollander, HongMei Han, Matthijs de Winter, Lennart Svensson, Sergej Masich, Bertil Daneholt, Lars Norlén
Improved knowledge of the topology of lamellar bodies is a prerequisite for a molecular-level understanding of skin barrier formation, which in turn may provide clues as to the underlying causes of barrier-deficient skin disease. The aim of this study was to examine the key question of continuity vs. discreteness of the lamellar body system using 3 highly specialized and complementary 3-dimensiona ...
Pages: 303-308
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INVESTIGATIVE REPORT
Quantitative Analysis of Formaldehyde-induced Fluorescence in Paraffin-embedded Specimens of Malignant Melanomas and Other Melanocytic Lesions
Hiroyuki Hara, Michiko Naito, Tomonori Harada, Isao Tsuboi, Tadashi Terui, Shin Aizawa
Inter-observer agreement is problematic in the histopathological diagnosis of melanoma and melanocytic naevi, even among expert pathologists. Formaldehyde-induced fluorescence (FIF) has been used for histochemical demonstration of catecholamines, 5-hydroxytryptamine and their immediate precursors. FIF can detect melanogenic activity and may be useful in differentiating malignant melanoma from othe ...
Pages: 309-313
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INVESTIGATIVE REPORT
Pathophysiological Study of Sensitive Skin
Virginie Buhé, Katell Vié, Christelle Guéré, Audrey Natalizio, Céline Lhéritier, Christelle Le Gall-Ianotto, Flavien Huet, Matthieu Talagas, Nicolas Lebonvallet , Pascale Marcorelles , Jean-Luc Carré, Laurent Misery
Sensitive skin is a clinical syndrome characterized by the occurrence of unpleasant sensations, such as pruritus, burning or pain, in response to various factors, including skincare products, water, cold, heat, or other physical and/or chemical factors. Although these symptoms suggest inflammation and the activation of peripheral innervation, the pathophysiogeny of sensitive skin remains unknown. ...
Pages: 314-318
Abstract  HTML  PDF
INVESTIGATIVE REPORT
Transient Receptor Potential Vanilloid-1 in Epidermal Keratinocytes May Contribute to Acute Pain in Herpes Zoster
Sang Bum Han, Hyeree Kim, Sang Hyun Cho, Jeong Deuk Lee, Jin Ho Chung, Hei Sung Kim
The role of transient receptor potential vanilloid-1 (TRPV1) in the initiation of neurogenic inflammation and transduction of pain is well established. In this study 33 patients with herpes zoster (HZ) were recruited from a single centre and underwent a questionnaire interview at their first visit. Punch biopsies from the HZ lesions and the contralateral unaffected skin were performed to localize ...
Pages: 319-322
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EDITORIAL COMMENT
Olive Oil, Sunflower Oil or no Oil for Baby Dry Skin or Massage: A Pilot, Assessor-blinded, Randomized Controlled Trial (the Oil in Baby SkincaRE [OBSeRvE] Study)
Alison Cooke, Michael J. Cork, Suresh Victor, Malcolm Campbell, Simon Danby, John Chittock, Tina Lavender
Topical oils on baby skin may contribute to development of childhood atopic eczema. A pilot, assessor-blinded, randomized controlled trial assessed feasibility of a definitive trial investigating their impact in neonates. One-hundred and fifteen healthy, full-term neonates were randomly assigned to olive oil, sunflower oil or no oil, twice daily for 4 weeks, stratified by family history of atopic ...
Pages: 323-330
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INVESTIGATIVE REPORT
Quality of Life, Emotional Wellbeing and Family Repercussions in Dermatological Patients Experiencing Chronic Itching: A Pilot Study
Servando E. Marron, Lucia Tomas-Aragones, Santiago Boira, Ricardo Campos-Rodenas
A better understanding of the psychosocial impact of chronic itching could lead to improved intervention strategies. The aim of this study is to examine the prevalence and characteristics of chronic itching in dermatological patients. The Itch Severity Scale (ISS) was completed by a sample of 201 patients from a Dermatology Outpatient Clinic in Spain and 61.69% (n = 124) of participant ...
Pages: 331-335
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INVESTIGATIVE REPORT
Self-reported Occupational Skin Exposure and Risk of Physician-certified Long-term Sick Leave: A Prospective Study of the General Working Population of Norway
Jose H. Alfonso, Tore Tynes, Jacob P. Thyssen, Jan-Øivind Holm, Håkon A. Johannessen
Little is known about the contribution of occupational skin exposure as a risk factor for physician-certified long-term sick leave in the general working population of Norway. This study drew a cohort (n = 12,255; response at baseline 69.9%) randomly from the general population of Norway. Occupational skin exposure (in 2009) was measured based on 5 items. The outcome of interest was ph ...
Pages: 336-340
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INVESTIGATIVE REPORT
Face-to-face Sun Protection Training and Text Messages Improve Sun Protection Behaviour in Adolescent Organ Transplant Recipients: HIPPOlino Feasibility Study
Michael M. Sachse, Silke Böttcher , Lars Pape, Gunnar Wagner, Otto Mehls , Günter Klaus , Gudrun Laschewski, Mareike Barz , Ingeborg Jahn , Hajo Zeeb
Adolescent organ transplant recipients have an increased risk of developing skin cancer. The aim of this study was to evaluate the technical feasibility and acceptability of short messaging service-based sun protection recommendations for adolescent patients. Sun-protective knowledge and behaviour were also evaluated using standardized questionnaires and telephone interviews. Twenty-six organ tran ...
Pages: 341-345
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CLINICAL REPORT
Real-life Data on Patient Characteristics, Cost and Effectiveness of Field-directed Treatment for Actinic Keratoses: An Observational Study
Margit C.J. van Rijsingen, Inge Seubring, Janneke P.C. Grutters, M. Birgitte Maessen-Visch, Hans A.C. Alkemade, Remco van Doorn, Hans Groenewoud, Peter C.M. van de Kerkhof, Gert Jan van der Wilt, Marie-Jeanne P. Gerritsen
Actinic keratoses (AK) occur frequently; however, real-life clinical data on personalized treatment choice and costs are scarce. This multicentre one-year observational study investigated patient-characteristics, cost and effectiveness of methylaminolaevulinate photodynamic therapy (MAL-PDT), imiquimod (IMI) and 5-fluorour-acil (5-FU) in patients with AKs on the face/scalp. A total of 104 patients ...
Pages: 346-350
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CLINICAL REPORT
Laser-mediated Photodynamic Therapy: An Alternative Treatment for Actinic Keratosis?
Janneke P.H.M. Kessels, Patty J. Nelemans, Klara Mosterd, Nicole W.J. Kelleners-Smeets, Gertruud A.M. Krekels, Judith U. Ostertag
Photodynamic therapy (PDT) with light emitting diode (LED) illumination is a frequently used treatment modality for actinic keratosis (AK) with excellent cosmetic outcome. A major disadvantage, however, is the high pain score. Pulsed dye laser (PDL) illumination has been suggested, but the long-term efficacy of this treatment is unknown. In this split-face study we prospectively treated 61 patient ...
Pages: 351-354
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CLINICAL REPORT
Patient Preferences for Treatment of Basal Cell Carcinoma: Importance of Cure and Cosmetic Outcome
Isabelle Martin, Marthe-Lisa Schaarschmidt, Anne Glocker, Raphael Herr, Astrid Schmieder, Sergij Goerdt, Wiebke K. Peitsch
Treatment options for localized resectable basal cell carcinoma (BCC) include micrographically controlled surgery, simple excision, curettage, laser ablation, cryosurgery, imiquimod, 5-fluorouracil, photodynamic therapy and radiotherapy. The aim of this study was to assess the preferences of patients with BCC for outcome (cure and recurrence rate, cosmetic outcome, risk of temporary and permanent ...
Pages: 355-360
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CLINICAL REPORT
Clinical Findings and Provision of Care in Haemodialysis Patients with Chronic Itch: New Results from the German Epidemiological Haemodialysis Itch Study
Kinan Hayani, Melanie Weiss, Elke Weisshaar
The German Epidemiological Haemodialysis Itch Study (GEHIS) has shown that more than one-third of haemodialysis (HD) patients have chronic itch (CI). As part of GEHIS, 216 patients with current CI were offered a dermatological examination, of whom 177 were investigated. According to the clinical classification of the International Forum for the Study of Itch (IFSI), 43.5% (n = 77) of t ...
Pages: 361-366
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CLINICAL REPORT
Validity of ABCD Rule of Dermoscopy in Clinical Practice
Ingela Ahnlide, Mats Bjellerup, Fredrik Nilsson, Kari Nielsen
The ABCD rule of dermoscopy was developed to facilitate the dermoscopic differentiation between benign and malignant melanocytic lesions. However, there is a lack of studies on its validity in clinical practice. The aim of this study was to evaluate the accuracy of the algorithm used bedside, compared with the accuracy of the preliminary preoperative diagnosis, and to rate physicians’ level of c ...
Pages: 367-372
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CLINICAL REPORT
Urticaria and Prodromal Symptoms Including Erythema Marginatum in Danish Patients with Hereditary Angioedema
Eva R. Rasmussen, Priscila Valente de Freitas, Anette Bygum
Erythema marginatum is a characteristic skin rash seen in patients with hereditary angioedema (HAE); however, it can be confused with urticaria, leading to delay in correct diagnosis. The aim of this study was to clarify how often erythema marginatum is misinterpreted as urticaria, potentially leading physicians to refrain from testing for HAE. Few studies have been published on urticaria and prod ...
Pages: 373-376
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CLINICAL REPORT
Phimosis with Preputial Fissures as a Predictor of Undiagnosed Type 2 Diabetes in Adults
Yun-Ching Huang, Yao-Kuang Huang , Chih-Shou Chen , Alan W. Shindel , Ching-Fang Wu, Jian-Hui Lin , Kuo-Hsiung Chiu, Tzu-Hsin Yang, Chung-Sheng Shi
Diabetes is usually asymptomatic in its early stage. Early diagnosis may improve outcomes by enabling initiation of treatment before end organ damage has progressed. The aim of this study was to determine whether the clinical sign of phimosis with preputial fissures is predictive of type 2 diabetes in patients not previously diagnosed with diabetes. Twenty-eight patients with acquired phimosis and ...
Pages: 377-380
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CLINICAL REPORT
Illness Perception in Primary Cutaneous T-cell Lymphomas: What Patients Believe About Their Disease
Johanna Eder, Martina Kammerstätter, Friedrich Erhart, Daniela Mairhofer-Muri, Franz Trautinger
There is currently no information available on illness perception in primary cutaneous T-cell lymphomas (CTCL). The aim of this study was therefore to gather initial information on disease understanding and interpretation in patients with CTCL. Consecutive patients from a hospital-based primary cutaneous lymphoma ward completed the Revised Illness Perception Questionnaire (IPQ-R) on 2 consecutive ...
Pages: 381-385
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SHORT COMMUNICATION
Interleukin-36γ (IL-1F9) Identifies Psoriasis Among Patients With Erythroderma
Johanna Braegelmann, Angelo Massimiliano D´Erme, Sidikov Akmal, Judith Maier, Christine Braegelmann, Jörg Wenzel
Abstract is missing (Short communication)
Pages: 386-387
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SHORT COMMUNICATION
Hand Eczema in Africa: Clinical Findings and Experiences from South-West Uganda
Stephen K. Mirembe, Grace K. Mulyowa, Gerold Jaeger, Robert Ofenloch, Thomas L. Diepgen, Elke Weisshaar
Abstract is missing (Short communication)
Pages: 388-389
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SHORT COMMUNICATION
Skin-Tissue-sparing Excision with Electrosurgical Peeling: A Case Series in Hidradenitis Suppurativa
Ineke C. Janse , Joke Hellinga, Janine L. Blok, Edwin R. van den Heuvel, Julia R. Spoo, Marcel F. Jonkman, Jorrit B. Terra, Barbara Horváth
Abstract is missing (Short communication)
Pages: 390-391
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SHORT COMMUNICATION
Oral Mucosal Lesions in Sarcoidosis: Comparison with Cutaneous Lesions
Marcello Menta S. Nico, Ana Lúcia Monteiro Guimarães, Paula Yume Sato Serzedello Correa, Silvia V. Lourenço
Abstract is missing (Short communication)
Pages: 392-393
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SHORT COMMUNICATION
Relapse Pattern and Treatment Outcome of Curative Radiotherapy for Primary Cutaneous CD30+ Anaplastic Large-cell Lymphoma: A Retrospective Cohort Study
Bing-Shen Huang, Wan-Yu Chen, Chun-Wei Wang, Ann-Lii Cheng, Ji-Hong Hong, Sung-Hsin Kuo
Abstract is missing (Short communication)
Pages: 394-395
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CLINICAL REPORT
Intralesional Rituximab Treatment for Primary Cutaneous B-cell Lymphoma: Nine Finnish Cases
Liisa Väkevä, Annamari Ranki, Tarja Mälkönen
Abstract is missing (Short communication)
Pages: 396-397
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SHORT COMMUNICATION
Clinical Characteristics of Pruritus in Neurofibromatosis 1
Emilie Brenaut, Constance Nizery-Guermeur , Séverine Audebert-Bellanger , Salah Ferkal , Pierre Wolkenstein, Laurent Misery, Claire Abasq-Thomas
Abstract is missing (Short communication)
Pages: 398-399
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SHORT COMMUNICATION
Development of an Allergen-induced Atopic Itch Model in Dogs: A Preliminary Report
Judy S. Paps, Wolfgang Bäumer, Thierry Olivry
Abstract is missing (Short communication)
Pages: 400-401
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SHORT COMMUNICATION
Lipid Content and Barrier Function Analysis in Uraemic Pruritus
Weronika Chorążyczewska, Adam Reich, Jacek C. Szepietowski
Abstract is missing (Short communication)
Pages: 402-403
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SHORT COMMUNICATION
Intraepidermal Nerve Fibre Density is Decreased in Lesional and Inter-lesional Prurigo Nodularis and Reconstitutes on Healing of Lesions
Svetlana Bobko, Claudia Zeidler, Nani Osada, Claudia Riepe, Bettina Pfleiderer, Esther Pogatzki-Zahn, Andrey Lvov, Sonja Ständer
Abstract is missing (Short communication)
Pages: 404-406
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SHORT COMMUNICATION
Diagnosis of Amelanotic Lentigo Maligna by Using In vivo Reflectance Confocal Microscopy
Angela Alani, Bart Ramsay, Kashif Ahmad
Abstract is missing (Short communication)
Pages: 406-407
Abstract  HTML  PDF
SHORT COMMUNICATION
Characterization of a Novel Mutation in the NCSTN Gene in a Large Chinese Family with Acne Inversa
Shide Zhang, Jin Meng, Miao Jiang, Jingjun Zhao
Abstract is missing (Short communication)
Pages: 408-409
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SHORT COMMUNICATION
Up-regulation of Activation Markers on Basophils in Patients with Papuloerythroderma
Hikari Otake, Atsushi Otsuka, Yumi Nonomura, Natsuko Iga, Kenji Kabashima
Abstract is missing (Short communication)
Pages: 410-411
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SHORT COMMUNICATION
Erythematous Variety of Bullous Pemphigoid: Case Report and Literature Review
Yukari Ise, Yasushi Suga, Kazuko Okumura, Osamu Negi, Norito Ishii, Takashi Hashimoto
Abstract is missing (Short communication)
Pages: 412-413
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SHORT COMMUNICATION
Paraneoplastic Epidermolysis Bullosa Acquisita Associated with Thyroid Carcinoma
Giuseppe Alfonso Lombardo, Maria Antonietta Pilla, Roberto Benucci, Alessandro Monopoli, Gianandrea Baliva, Tommaso Gobello, Giovanni Di Zenzo, Giovanna Zambruno, Liliana Guerra
Abstract is missing (Short communication)
Pages: 414-415
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SHORT COMMUNICATION
Bullous Delayed Pressure Urticaria Responding to Omalizumab
Sabine Müller, David Rafei-Shamsabadi, Kristin Technau-Hafsi, Sophia Renzel, Thilo Jakob
Abstract is missing (Short communication)
Pages: 416-417
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SHORT COMMUNICATION
Solitary Plaque-type Morphea with Dystrophic Calcinosis Cutis
Gustavo Deza, Julia Maria Sánchez-Schmidt, Ramon M. Pujol
Abstract is missing (Short communication)
Pages: 418-419
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SHORT COMMUNICATION
Emergence of Photosensitivity with Decreased Treg Cells in a Patient with Mycosis Fungoides Treated with Anti-CC Chemokine Receptor 4 Antibody Mogamulizumab
Kazuki Tatsuno, Tomohiro Sano, Kensuke Fukuchi, Sachiko Kuriyama, Masahiro Aoshima, Akira Kasuya, Shigeki Ikeya, Toshiharu Fujiyama, Taisuke Ito, Yoshiki Tokura
Abstract is missing (Short communication)
Pages: 420-421
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SHORT COMMUNICATION
Borderline Lepromatous Leprosy: Cutaneous Manifestation and Type 1 Reversal Reaction
Mai Hattori , Sei-ichiro Motegi, Hiroo Amano, Norihisa Ishii, Osamu Ishikawa
Abstract is missing (Short communcation)
Pages: 422-423
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SHORT COMMUNICATION
Identification of a Novel Mutation in the SLC39A4 Gene in a Case of Acrodermatitis Enteropathica
Rüdiger Panzer, Sébastien Küry, Sébastien Schmitt, Regina Fölster-Holst
Abstract is missing (Short communication)
Pages: 424-425
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LETTER TO THE EDITOR
A Place for BRAFV600E Mutation-specific Immunohistochemistry Alongside Cell-free DNA Mutation Detection in Melanoma
Arnaud Uguen, Matthieu Talagas, Marc De Braekeleer , Pascale Marcorelles
Abstract is missing (Letter to the Editor)
Pages: 426-427
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QUIZ
Keratotic Nodule on The Heel: A Quiz
Paloma Nogueras-Morillas, Gonzalo Blasco-Morente , Beatriz Espadafor-López, José Aneiros-Fernández, Jesús Tercedor-Sánchez
Abstract is missing (Quiz)
Pages: 427-431
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QUIZ
Violaceous and Petechial Persistent Plantar Plaques: A Quiz
Ignacio Gómez-Martín, Gemma Martín-Ezquerra, Ramon M. Pujol
Abstract is missing (Quiz)
Pages: 427-431
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QUIZ
Giant Ulcer on Abdominal Wall: A Quiz
Hao Guo, Jiu-Hong Li, Xiao-Yi Yang , Xiao-Lu Wang , Jie Cao , Song Zheng, Hong-Duo Chen
Abstract is missing (Short communication)
Pages: 427-431
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