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These articles have been accepted for publication in Acta Dermato-Venereologica and are currently being edited and typeset. Readers should note that articles published below have been fully refereed, but have not been through the copy-editing and proof correction process. Only Abstract is possible to read. When this process is finalized the complete paper will be able to find.
INVESTIGATIVE REPORT
Suicidal Ideation in Adult Patients with Atopic Dermatitis: A German Cross-sectional Study
Jan Dieris-Hirche, Uwe Gieler, Frank Petrak, Wolfgang Milch, Bert te Wildt, Barbara Dieris, Stephan Herpertz
A cross-sectional study was performed to assess symptoms of suicidality, depression and anxiety in adult patients with atopic dermatitis. The study describes the relationships between these psychiatric symptoms and skin-specific factors, such as atopic dermatitis severity and skin satisfaction. A sample of 181 German patients with atopic dermatitis was compared with a control group of 64 persons w ...
Abstract
INVESTIGATIVE REPORT
Rasch Analysis of the Dermatology Life Quality Index Reveals Limited Application to Chinese Patients with Skin Disease
Zehui He, Riccardo Lo Martire, Chuanjian Lu, Hongxia Liu, Lin Ma, Ying Huang, Yongmei Li, Liyun Sun, Yanping Bai, Wali Liu, Xushan Zha
The objective of this study was to examine the psychometric properties of the Chinese version of the Dermatology Life Quality Index (DLQI) and to assess the invariance of its items with respect to several patient parameters via Rasch analysis. Data were aggregated from 9,845 patients with various skin diseases across 9 hospitals in different regions of China. The response structure, local independ ...
Abstract
INVESTIGATIVE REPORT
Autoimmune Disease in Children and Adolescents with Psoriasis: A Cross-Sectional Study in Denmark
Christoffer Blegvad, Alexander Egeberg, Tilde E. Tind Nielsen, Gunnar H. Gislason, Claus Zachariae, Anne-Marie Nybo Andersen, Lone Skov
Psoriasis is an immune-mediated inflammatory disease, which, in studies among adults, have been shown to cluster with autoimmune disease. The aim of this cross-sectional register study was to examine possible associations between 9 pre-selected autoimmune diseases and psoriasis in children and adolescents. The study population consisted of all individuals living in Denmark, age under 18 years on 3 ...
SHORT COMMUNICATION
Photodynamic Therapy with Red Light and 5-Aminolaevulinic Acid for Herpes Simplex Recurrence: Preliminary Results
Beata J. Osiecka, Piotr Nockowski, Stanisław Kwiatkowski, Jacek C. Szepietowski
Abstract is missing (Short communication)
SHORT COMMUNICATION
Use of Molecular Biology Techniques in Sarcoidal Granulomatous Dermatitis: A Clinicopathological and Molecular Approach with Diagnostic Implications
Tiago C. Esteves, Teresa Tórtola, Berta Ferrer, Gloria Aparicio, Elena Sulleiro, Juanjo González-López, Zaira Moure, Dani Romero, Vicente Garcia-Patos
Abstract is missing (Short communication)
CLINICAL REPORT
Mycoplasma genitalium and Macrolide Resistance-associated Mutations in the Skåne Region of Southern Sweden 2015
Ola Forslund, Max Hjelm, Ragghd El-Ali, Annika Johnsson, Carina Bjartling
Mycoplasma genitalium is a sexually transmitted infection ordinarily treated with azithromycin. Emerging resistance to macrolide is linked to mutations in the 23S rRNA gene. We analysed the frequency of such mutations of M. genitalium isolates from patients that were symptomatic, and from sexual partners of symptomatic individuals, from October to December of 2015, in the Skåne Region of Sweden ...
SHORT COMMUNICATION
Trichomonas vaginalis is Rare Among Women in Iceland
Ingibjorg Hilmarsdottir, Erna Sigmundsdottir, Audur Eiriksdottir, Daniel Golparian, Magnus Unemo
Abstract is missing (Short communication)
CLINICAL REPORT
Circulating Tumour DNA for Monitoring Treatment Response to Anti-PD-1 Immunotherapy in Melanoma Patients
Atsuko Ashida, Kaori Sakaizawa, Hisashi Uhara, Ryuhei Okuyama
Anti-programmed cell death-1 (anti-PD-1) antibody shows high therapeutic efficacy in patients with advanced melanoma. However, assessment of its therapeutic activity can be challenging because of tumour enlargement associated with intratumoural inflammation. Because circulating tumour DNA (ctDNA) correlates with tumour burden, we assessed the value of ctDNA levels as an indicator of tumour changes ...
SHORT COMMUNICATION
Agreement Between Self-reported Inflammatory Skin Disorders and Dermatologists’ Diagnosis: A Cross-sectional Diagnostic Study
Céline Phan, Khaled Ezzedine, Cindy Lai, Laurence Le Cleach, Oliver Cogrel, Laurence Fardet, Pierre Wolkenstein, Olivier Chosidow, Marie Beylot-Barry, Emilie Sbidian
Abstract is missing (Short communication)
SHORT COMMUNICATION
Cutis Verticis Gyrata Fluctuation with Atopic Dermatitis Disease Activity
Hideyuki Kosumi, Kentaro Izumi, Ken Natsuga, Yasuyuki Yamaguchi, Akira Itami, Hiroshi Shimizu
Abstract is missing (Short communication)
SHORT COMMUNICATION
Consumer Behaviour Among Nickel-allergic Patients
Malin G. Ahlström, Jacob P. Thyssen, Torkil Menné, Jeanne D. Johansen
Abstract is missing (Short communication)
SHORT COMMUNICATION
Lipoid Proteinosis: A Previously Unrecognized Mutation and Therapeutic Response to Acitretin
Claudia Carnevale, Daniele Castiglia, Andrea Diociaiuti, Vittoria Proto, Simona Giancristoforo, Renata Boldrini, Giovanna Zambruno, Maya El Hachem
Abstract is missing (Short communication)
INVESTIGATIVE REPORT
Efficacy of a Daily Protective Moisturizer with High UVB and UVA Photoprotection in Decreasing Ultraviolet Damage: Evaluation by Reflectance Confocal Microscopy
Antonio Gomes-Neto, Paula Aguilera, Leonor Prieto, Sophie Seité, Dominique Moyal, Cristina Carrera, Josep Malvehy, Susana Puig
Patients with photodermatoses or actinic keratoses benefit from very high ultraviolet B-ultraviolet A (UVB-UVA) photoprotection. However, poor compliance is an issue that jeopardizes adequate protection, leading to disease recurrence. This study evaluated the efficacy of a daily protective moisturizer with high UVB and UVA photoprotection applied 8 h before irradiation. A monocentric, open-label, ...
CLINICAL REPORT
Evaluation of a Rapid, Fully Automated Platform for Detection of BRAF and NRAS Mutations in Melanoma
Fanny Barel, Briac Guibourg, Laetitia Lambros, Glen Le Flahec, Pascale Marcorelles, Arnaud Uguen
BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration. We compared the rapid, real-time, fully automated molecular diagnosis platform Idylla™ with next-generation sequencing (NGS) and immunohistochemistry for detection of BRAF and NRAS mutations in 36 patients with metastatic melanomas. The I ...
INVESTIGATIVE REPORT
Mineral Depositions of Calcifying Skin Disorders are Predominantly Composed of Carbonate Apatite
Michael Franzen, Elena Müller-More, Janne Cadamuro, Josef Koller, Wolfgang Salmhofer, Iris Wohlmuth-Wieser, Cornelia Kronberger, Hermann Salmhofer
Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization. Studies on the pathophysiology of mineral compositions and effective treatment modalities are limited. We therefore studied 14 patients with subcutaneous calcifications. Mineral material was collected and analysed by Fourier transform infrared spectrometry. Blood analyses were run to ...
QUIZ
A Pinkish-Blue Exophytic Nodule on the Arm of an Elderly Man: A Quiz
Calogero Pagliarello, Ignazio Stanganelli, Roberto Ricci, Claudio Feliciani, Sergio Di Nuzzo
Abstract is missing (Quiz)
INVESTIGATIVE REPORT
Distraction From Itch Shows Brainstem Activation Without Reduction in Experimental Itch Sensation
Astrid Stumpf, Bettina Pfleiderer, Gudrun Schneider, Gereon Heuft, Martin Schmelz, Ngoc Quan Phan, Sonja Ständer, Markus Burgmer
The central processing of itch is not completely understood. This is the first study to use functional magnetic resonance imaging (fMRI) to examine the central modulation by distraction of experimentally induced itch. A total of 33 healthy volunteers were examined with fMRI. Periods of itch induction without distraction and itch with distraction by a Stroop task were counterbalanced during the sca ...
REVIEW
Henoch-Schönlein Purpura: A Literature Review
Liv Eline Hetland, Kjærsti Sørensen Susrud , Kim Hein Lindahl, Anette Bygum
Henoch-Schönlein purpura is the most common childhood vasculitis, but may also affect adults. This article reviews the literature since 2011 on advances in diagnosis, clinical disease manifestations, pathophysiology and treatment of Henoch-Schönlein purpura. The clinical manifestations are thought to arise from IgA depositions in blood vessel walls in the affected organs, mostly skin, gastro ...
INVESTIGATIVE REPORT
Increased Interleukin-19 Expression in Cutaneous T-cell Lymphoma and Atopic Dermatitis
Tomonori Oka, Makoto Sugaya, Naomi Takahashi, Rina Nakajima, Sayaka Otobe, Miyoko Kabasawa, Hiraku Suga, Tomomitsu Miyagaki, Yoshihide Asano, Shinichi Sato
Interleukin-19 (IL-19), a pro-inflammatory cytokine known to stimulate the production of T helper type 2 (Th2) cytokines, is induced by IL-17A and highly expressed in the lesional skin of psoriasis and atopic dermatitis (AD). This aim of this study was to investigate whether IL-19 is involved in cutaneous T-cell lym­phoma (CTCL) and AD. IL-19 levels were significantly higher in the sera of pati ...
QUIZ
A Large Skin-colored Nodule on the Plantar Foot: A Quiz
Nathan W. Rojek, Veselina Korcheva, Sancy A. Leachman
Abstract is missing (Quiz)
SHORT COMMUNICATION
Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma with Brain Involvement and Mimicking Dermatomyositis
Hitoshi Terui, Kenshi Yamasaki, Saaya Yoshida, Setsuya Aiba
Abstract is missing (Short communication)
INVESTIGATIVE REPORT
Pemphigus Vulgaris and Pemphigus Foliaceus: Differences in Epidemiology and Mortality
Khalaf Kridin, Shira Zelber-Sagi, Reuven Bergman
Little is known about differences in epidemiological features and prognosis between pemphigus vulgaris (PV) and pemphigus foliaceus (PF). The objective of this study was to compare PV and PF patients regarding ethnic variations and mortality rates. Mortality of PV and PF patients was compared with age- and sex-matched control subjects in the general population. The study cohort comprised 207 patie ...
CLINICAL REPORT
Diagnostic Efficacy of Digital Dermoscopy and Clinical Findings in Thin Melanoma of the Lower Limbs
Emi Dika, Marco Adriano Chessa, Simone Ribero, Pier A. Fanti, Carlotta Gurioli, Martina Lambertini, Carlotta Baraldi, Annalisa Patrizi
The introduction of dermoscopy has improved the accuracy of diagnosis of melanoma. However, early stage melanoma can be difficult to diagnose. Eighty-nine cases of thin melanoma with a Breslow thickness ≤1 mm located on the lower limb and diagnosed between 2008 and 2016 were assessed using 4 dermoscopic algorithms: (i) modified pattern analysis; (ii) ABCD rule of dermoscopy; (iii) 7-point ch ...
SHORT COMMUNICATION
No Viral Transcripts Associated with Folliculotropic Mycosis Fungoides Using a High Throughput Sequencing Approach
Aurélie Du-Thanh, Olivier Dereure, Justine Cheval, Marine Dumarest, Liza Al-Shikhley, Céline Girard, Bernard Guillot, Marc Eloit
Abstract is missing (Short communication)
SHORT COMMUNICATION
Locally Aggressive Trichoblastic Tumours (Low-grade Trichoblastic Carcinomas): Clinicopathological Analysis and Follow-up
Camille Hua, Charles Velter, Amelie Osio, Céleste Lebbe, Nicole Basset-Seguin, Bernard Cribier, Maxime Battistella
Abstract is missing (Short communication)
SPECIAL REPORT
The Role of Topical Timolol in the Treatment of Infantile Hemangiomas: A Systematic Review and Meta-analysis
Maham Khan, Aaron Boyce, David Prieto-Merino, Åke Svensson, Emma Wedgeworth, Carsten Flohr
To date the efficacy and safety of topical timolol in the treatment of infantile hemangioma has not be reviewed and analysed systematically. We collated all published data on the efficacy and safety of topical timolol in the treatment of infantile hemangioma. A total of 31 studies with 691 patients were included. The fixed effects pooled estimate of the response rate defined as any improvement fro ...
BOOK REVIEW
Hurwitz Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence, 5th Edition
Regina Fölster-Holst
Abstract is missing (Book review)
BOOK REVIEW
Skin Barrier Function
Magnus Lindberg
Abstract is missing (Book review)
BOOK REVIEW
Current Problems in Dermatology, Vol. 48. Tattooed Skin and Health
Kristian Thestrup-Pedersen
Abstract is missing (Book review)
BOOK REVIEW
Chemical Immunology and Allergy, Vol. 100. History of Allergy
Carl-Fredrik Wahlgren
Abstract is missing (Book review)