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These articles have been accepted for publication in Acta Dermato-Venereologica and are currently being edited and typeset. Readers should note that articles published below have been fully refereed, but have not been through the copy-editing and proof correction process. Only Abstract is possible to read. When this process is finalized the complete paper will be able to find.
QUIZ
Pruritic Erythematous Macules in a Patient with Systemic Sarcoidosis: A Quiz
Astrid Herzum, Mattia Fabio Molle, Emanuele Cozzani, Martina Burlando, Pietro Paolo Tavilla, Claudia Micalizzi, Ilaria Trave, Aurora Parodi
Abstract is missing (Quiz)
Abstract
INVESTIGATIVE REPORT
Epidemiology, Comorbidity and Risk Factors for Psoriatic Arthritis: a Health Insurance Claims Database Analysis
Maximilian Reinhardt, Claudia Garbe, Jana Petersen, Matthias Augustin, Nathalia Kirsten, Mona H.C. Biermann, Benjamin Häberle, Kristina Hagenström
Psoriatic arthritis is a frequent manifestation of psoriasis, and has a high level of impact on physical functioning, work ability and quality of life. However, there have been few studies of the epidemiology, development of, and risk factors for concomitant psoriatic arthritis in patients with psoriasis. This study analysed data from a German public health insurance database of >2 million individ ...
Abstract
SHORT COMMUNICATION
More about Zlotnikov, the Man Who Explained Blaschko’s Lines to be a Mosaic
Rudolf Happle, Eckart Haneke
Abstract is missing (Short communication)
Abstract
CLINICAL REPORT
Influence of Port-wine Stains on Quality of Life of Children and Their Parents
Fan Jiang, Junyi Shao, Lele Chen, Nali Yang, Jingjing Liu, Zhiming Li
Port-wine stains are congenital vascular malformations that affect the quality of life of children and their parents. This study used the Family Dermatology Life Quality Index and Children’s Dermatology Life Quality Index to examine the effects of port-wine stains on the quality of life of children and their parents, including an in-depth, systematic analysis of the moderating effects of the chi ...
Abstract
REVIEW
Patient-reported Outcome Measures in Dermatology: A Systematic Review
Rachael L. Pattinson, Nirohshah Trialonis-Suthakharan, Sunnia Gupta, Alasdair L. Henry, Jacqueline F. Lavallée, Marina Otten, Timothy Pickles, Nick Courtier, Jennifer Austin, Christine Janus, Matthias Augustin, Chris Bundy
By relying on data from existing patient-reported outcome measures of quality of life, the true impact of skin conditions on patients’ lives may be underestimated. This study systematically reviewed all dermatology-specific (used across skin conditions) patient-reported outcome measures and makes evidence-based recommendations for their use. The study protocol is registered on PROSPERO (CRD42018 ...
Abstract
SHORT COMMUNICATION
Syringotropic Mycosis Fungoides with Vasculopathic Ulcers and Expression of T-follicular-helper Cell Markers
Emmanuel Ribereau-Gayon, Joann Le Borgne De Lavillandre, Thibaut Deschamps, Brigitte Balme, Olivier Harou, Florent Grange
Abstract is missing (Short Communication)
Abstract
QUIZ
Persistent Widespread Pruritic Nodules: A Quiz
Hong-Hao Hu, Wen-Jia Yang, Jiu-Hong Li, Hao Guo
Abstract is missing (Quiz)
Abstract
SHORT COMMUNICATION
Comorbidities of Prurigo Nodularis in Finland Between 1996 and 2019
Kristian Wikström, Henri Verkko, Suvi-Päivikki Sinikumpu, Jari Jokelainen, Kaisa Tasanen, Laura Huilaja
Abstract is missing (Short Communication)
Abstract
SHORT COMMUNICATION
Complexity of Transcriptional and Translational Interference of Laminin-332 Subunits in Junctional Epidermolysis Bullosa with LAMB3 Mutations
Ping-Chen Hou, Ken Natsuga, Wei-Ting Tu, Hsin-Yu Huang, Brandon Chen, Liang-Yu Chen, Wan-Rung Chen, Yi-Kai Hong, Yen-An Tang, Julia Yu-Yun Lee, Peng-Chieh Chen, H. Sunny Sun, John A. McGrath, Chao-Kai Hsu
Abstract is missing (Short communication)
Abstract
CLINICAL REPORT
Cutaneous Squamous Cell Carcinoma in Epidermolysis Bullosa: a 28-year Retrospective Study
Susan J. Robertson, Elizabeth Orrin, Manpreet K. Lakhan, Gavin O’Sullivan, Jessie Felton, Alistair Robson, Danielle T. Greenblatt, Catina Bernardis, John A. McGrath, Anna E. Martinez, Jemima E. Mellerio
Epidermolysis bullosa (EB), notably severe recessive dystrophic EB (RDEB-S), is associated with increased risk of aggressive mucocutaneous squamous cell carcinomas, the major cause of mortality in early adulthood. This observational, retrospective case review describes a series of EB patients with cutaneous squamous cell carcinomas over a 28-year period. Forty-four EB patients with squamous cell c ...
Abstract
SHORT COMMUNICATION
Effect Modification by Smoking Status on the Association Between Psoriasis and Chronic Obstructive Pulmonary Disease among Adults in the USA
Jeffrey Liu, Amylee Martin, Akshitha Thatiparthi, Jashin J. Wu
Abstract is missing (Short Communication)
Abstract
INVESTIGATIVE REPORT
Wearing Occlusive Gloves Increases the Density of Staphylococcus aureus in Patients with Hand Eczema
Line Brok Nørreslet, Sofie Marie Edslev, Esben Meulengracht Flachs, Niels Erik Ebbehøj, Paal Skytt Andersen, Tove Agner
Hand eczema is frequently colonized with Staphylococcus aureus. Some patients with hand eczema wear occlusive gloves regularly; however, the effect of this on the density of S. aureus is unexplored. The aim of this study is to examine the effect of occlusive gloves on the density of S. aureus sampled from the hands of patients with hand eczema. In an experimental set-up, patients with moderate-to- ...
Abstract
INVESTIGATIVE REPORT
Activation of Transient Receptor Potential Vanilloid-3 Channels in Keratinocytes Induces Pruritus in Humans
Jin Cheol Kim, Han Bi Kim, Won-Sik Shim, In Suk Kwak, Bo Young Chung, Seok Young Kang, Chun Wook Park, Hye One Kim
Carvacrol, a natural transient receptor potential vanilloid-3 activator, has been reported to cause pruritus in mice. This study aimed to evaluate the effects of carvacrol and various antipruritic agents in humans. A stimulation test with carvacrol, β-alanine, and histamine was performed. After application of the pruritic solutions, the skin was stimulated with pinpricks. In inhibition test A, Fo ...
Abstract
REVIEW
Diagnostic Accuracy of Trichoscopy in Trichotillomania: A Systematic Review
Agnieszka Kaczorowska, Lidia Rudnicka, Catherine M. Stefanato, Anna Waskiel-Burnat, Olga Warszawik-Hendzel, Malgorzata Olszewska, Adriana Rakowska
Trichotillomania is classified as a mental health disorder, but it is commonly diagnosed by dermatologists. The aim of this systematic review is to assess the diagnostic value of trichoscopy in diagnosing trichotillomania. The analysis identified the 7 most specific trichoscopic features in trichotillomania. These features had the following prevalence and specificity: trichoptilosis (57.5%; 73/127 ...
Abstract
QUIZ
Petechial Purpura on the Lower Legs: A Quiz
Benjamin Klein, Kristin Küpper, Jan Christoph Simon
Abstract is missing (Quiz)
Abstract
CLINICAL REPORT
Effectiveness of Apremilast in Real Life in Patients with Psoriasis: A Longitudinal Study
Giovanna Malara, Cristina Politi, Caterina Trifirò, Chiara Verduci, Graziella D'Arrigo, Alessandra Testa, Giovanni Tripepi
Apremilast is an oral selective phosphodiesterase-4 inhibitor developed recently for psoriasis treatment. The aim of this study is to assess the real-life outcomes of use of apremilast in patients with psoriasis in everyday clinical practice. A total of 159 adult patients (90 males) with plaque psoriasis were included in the study. Fifty of the patients (31%) had psoriatic arthritis. All patients ...
Abstract
INVESTIGATIVE REPORT
Teledermatology in Primary Care in Singapore: Experiences of Family Doctors and Specialists
Aloysius Chow, Sok Huang Teo, Jing Wen Kong, Simon Biing Ming Lee, Yee Kiat Heng, Maurice A.M. van Steensel, Helen E. Smith
Most teledermatology studies focus on patients’ satisfaction; fewer focus on the experiences of healthcare professionals. This qualitative study explored healthcare professionals’ perceptions of teledermatology used for linking public primary care clinics with the specialist dermatology centre in Singapore. Semi-structured in-depth interviews were conducted with 25 family physicians and dermat ...
Abstract
CLINICAL REPORT
Survival of Adjuvant Drugs for Treatment of Pemphigus: A Population-based Cohort Study
Khalaf Kridin, Christoph M. Hammers, Ralf J. Ludwig, Dana Tzur Bitan, Arnon D. Cohen
Drug survival reflects the real-life efficacy and safety of therapeutic agents. Evidence regarding the durability of adjuvant agents in the treatment of pemphigus is sparse. The aims of this study were to investigate the survival of adjuvant agents used to manage patients with pemphigus, and to identify predictors of treatment dropout. A retrospective population-based cohort study was designed to ...
Abstract
CLINICAL REPORT
Secukinumab Exhibits Sustained and Stable Response in Patients with Moderate-to-Severe Psoriasis: Results from the SUPREME Study
Antonio Costanzo, Filomena Russo, Marco Galluzzo, Luca Stingeni, Roberta Scuderi, Leonardo Zichichi, Manuela Papini, Luisa Di Costanzo, Andrea Conti, Martina Burlando, Andrea Chiricozzi, Francesca Maria Gaiani, Cristina Mugheddu, Maria Letizia Musumeci, Paolo Gisondi, Stefano Piaserico, Paolo Dapavo, Marina Venturini, Gianluca Pagnanelli, Paolo Amerio, Concetta Potenza, Ketty Peris, Franca Cantoresi, Sara Trevisini, Francesco Loconsole, Annamaria Offidani, Santo Raffaele Mercuri, Viviana Lora, Francesca Prignano, Marta Bartezaghi, Giovanni Oliva, Elisabetta Aloisi, Roberto Orsenigo for the SUPREME study group
Secukinumab, a fully human monoclonal antibody, neutralizes interleukin-17A, a cornerstone cytokine driving the multiple manifestations of psoriasis. This post-hoc analysis of the SUPREME study was performed to determine the sustainability of response to secukinumab in terms of Psoriasis Area and Severity Index (PASI) 90 in patients with moderate-to-severe plaque psoriasis. Based on PASI 90 respon ...