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INVESTIGATIVE REPORT
Estimation of Direct Melanoma-related Costs by Disease Stage and by Phase of Diagnosis and Treatment According to Clinical Guidelines
Alessandra Buja, Gino Sartor, Manuela Scioni, Antonella Vecchiato, Mario Bolzan, Vincenzo Rebba, Vanna Chiarion Sileni, Angelo Claudio Palozzo, Maria Montesco, Paolo Del Fiore, Vincenzo Baldo, Carlo Riccardo Rossi
Cutaneous melanoma is a major concern in terms of healthcare systems and economics. The aim of this study was to estimate the direct costs of melanoma by disease stage, phase of diagnosis, and treatment according to the pre-set clinical guidelines drafted by the AIOM (Italian Medical Oncological Association). Based on the AIOM guidelines for malignant cutaneous melanoma, a highly detailed decision ...
Abstract  PDF
SHORT COMMUNICATION
Allergic Contact Dermatitis Due to Ripasudil Hydrochloride Hydrate in Eye-drops: A Case Report
Minori Kusakabe, Yasutomo Imai, Masaru Natsuaki, Kiyofumi Yamanishi
Abstract is missing (Short communication)
Abstract  PDF
INVESTIGATIVE REPORT
Search for RASA1 Variants in Capillary Malformations of the Legs in 113 Children: Results From the French National Paediatric Cohort CONAPE
Annabel Maruani, Marine Durieux-Verde, Juliette Mazereeuw-Hautier, Olivia Boccara, Ludovic Martin, Christine Chiaverini, Catherine Eschard, Nathalie Bénéton, Pierre Vabres, Xavier Balguerie, Patrice Plantin, Didier Bessis, Sébastien Barbarot, Ali Dadban, Catherine Droitcourt, Aline Berthelot, Gérard Lorette, Sophie Leducq, Mahtab Samimi, Christian Andres, Agnès Caille, Patrick Vourc'h; and Groupe de Recherche de la Société Française de Dermatologie
Patients with an inherited autosomal-dominant disorder, capillary malformation–arteriovenous malformation (CM-AVM), frequently have mutations in Ras P21 protein activator 1 (RASA1). The aims of this study were to determine the prevalence of germline RASA1 variants in a French multicentre national cohort of children, age range 2–12 years, with sporadic occurrence of capillary malformation (CM) ...
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INVESTIGATIVE REPORT
Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
Marthe-Lisa Schaarschmidt, Raphael Herr, Mandy Gutknecht, Katharina Wroblewska, Sascha Gerdes, Michael Sticherling, Matthias Augustin, Wiebke K. Peitsch
Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients’ (n = 222) and physicians’ (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using the Relative Importance Score (RIS) for each attribute calculated by dividing the attribute’s range by the sum of all attribute ...
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SPECIAL REPORT
Fractional Carbon Dioxide Laser as an "Add-on" Treatment for Vitiligo: A Meta-analysis with Systematic Review
Hyun Jung Kim, Eun Sun Hong, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
Treatment of vitiligo is challenging and requires a multidisciplinary approach. Fractional carbon dioxide (CO2) laser as an add-on to conventional treatment has been reported to be effective, but there is no consensus on its use. A systematic review was performed by searching major databases for relevant publications to February 2017. Six studies with 85 participants were included. For those with ...
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REVIEW
Chronic Prurigo of Nodular Type: A Review
Claudia Zeidler, Athanasios Tsianakas, Manuel Pereira, Hartmut Ständer, Gil Yosipovitch, Sonja Ständer
Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules. PN evolves along with chronic pruritus in the context of diverse dermatological, systemic, neurological or psychiatric conditions. Permanent scratching is possibly a major trigger of PN, although its exact pathophysiology remain ...
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CLINICAL REPORT
Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area
Eriika Mansikka, Teea Salmi, Katri Kaukinen, Pekka Collin, Heini Huhtala, Timo Reunala, Kaisa Hervonen
Dermatitis herpetiformis (DH) is an extra-intestinal manifestation of coeliac disease. The highest currently reported prevalence of DH is in Finland, but knowledge of diagnostic delay is limited. This study investigated the duration of rash prior to diagnosis in 446 patients with DH, analysing the results in 3 periods of 15 years. The diagnosis was considered delayed when the duration of rash befo ...
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QUIZ
Chronic Nodular Dermatosis: A Quiz
Marco Cusini, Stefano Ramoni, Vinicio Boneschi, Sebastiano Recalcati
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Late-onset Erythropoietic Protoporphyria Associated with Myelodysplastic Syndrome Treated with Azacitidine
Ai Yoshioka, Susumu Fujiwara, Hiroki Kawano, Hajime Nakano, Shigeru Nakano, Toshimitsu Matsui, Yoshio Katayama, Chikako Nishigori
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Heterogeneity of Skin Re-innervation After Burns and Factors Involved in its Regulation: A Pilot Study
Virginie Buhé, Alexandra Trimaille, Martine Schollhammer, Florence Morvan, Weiguo Hu, Christophe Egles, Alexis Desmoulière, Laurent Misery
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Modified Measles: A Diagnostic Challenge
Jozefien Roose, Celine Rohaert, Annelien Jadoul, Regina Fölster-Holst, Dirk van Gysel
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Patients' Illness Perception as a Tool to Improve Individual Disease Management in Primary Cutaneous Lymphomas
Stefanie Porkert, Eva Lehner-Baumgartner, Julia Valencak, Robert Knobler, Elisabeth Riedl, Constanze Jonak
The Revised Illness Perception Questionnaire (IPQ-R) has been shown to assess illness perception reproducibly in primary cutaneous T-cell lymphomas (CTCL). Illness perception reflects patients' individual concepts of understanding and interpretation of the disease, influencing illness behaviour and health-related quality of life (HRQOL). This study investigated the clinical relevance of the relati ...
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INVESTIGATIVE REPORT
Placebo Effects of Open-label Verbal Suggestions on Itch
Stefanie H. Meeuwis, Henriët van Middendorp, Dieuwke S. Veldhuijzen, Antoinette I.M. van Laarhoven, Jan De Houwer, Adriana P.M. Lavrijsen, Andrea W.M. Evers
Placebo effects are positive outcomes that are not due to active treatment components, which may be elicited even when patients are aware of receiving an inert substance (open-label). This proof-of-principle study investigated for the first time whether open-label placebo effects on itch can be induced by verbal suggestions alone. Ninety-two healthy volunteers were randomized to experimental (open ...
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INVESTIGATIVE REPORT
Cutaneous Chronic Graft Versus Host Disease Following Allogeneic Haematopoietic Stem Cell Transplantation in Children: A Retrospective Study
Rony Shreberk-Hassidim, Michal Neumark, Shoshana Greenberger, Gal Goldstein, Ayal Hassidim, Yuval Dukler, Alexander Maly, Polina Stepensky, Vered Molho-Pessach
Chronic graft versus host disease (cGVHD) is a complication of allogeneic haematopoietic stem cell transplantation (HSCT). The aim of this study was to clinically characterize childhood cutaneous cGVHD. A retrospective study of children treated with HSCT at 2 tertiary medical centres in Israel between 2011 and 2014 was performed. A total of 112 children were included. Cutaneous cGVHD developed in ...
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CLINICAL REPORT
Burden of Aquagenic Pruritus in Polycythaemia Vera
Edyta Lelonek, Łukasz Matusiak, Tomasz Wróbel, Jacek Kwiatkowski, Jacek C. Szepietowski
Aquagenic pruritus (AP) has a significant influence on quality of life (QoL) in patients with polycythaemia vera. This study analysed the impact of AP on patient well-being in 102 patients with polycythaemia vera. Intensity of pruritus was evaluated using a visual analogue scale (VAS), verbal rating scale (VRS) and a 4-item Itch Questionnaire. Psychosocial aspects of AP were assessed with the Hosp ...
Abstract  PDF
SHORT COMMUNICATION
Central Obesity in Children with Psoriasis
Lucia Guidolin, Marco Borin, Elena Fontana, Francesca Caroppo, Stefano Piaserico, Anna Belloni Fortina
Abstract is missing (Short communication)
Abstract  PDF
CLINICAL REPORT
Nail Involvement in Alopecia Areata: A Questionnaire-based Survey on Clinical Signs, Impact on Quality of Life and Review of the Literature
Yvonne B.M. Roest, Henriët van Middendorp, Andrea W.M. Evers, Peter C.M. van de Kerkhof, Marcel C. Pasch
Alopecia areata (AA) is an immune-mediated disease causing temporary or permanent hair loss. Up to 46% of patients with AA also have nail involvement. The aim of this study was to determine the presence, types, and clinical implications of nail changes in patients with AA. This questionnaire-based survey evaluated 256 patients with AA. General demographic variables, specific nail changes, nail-rel ...
Abstract  PDF
INVESTIGATIVE REPORT
Temporal Stability of the Healthy Human Skin Microbiome Following Dead Sea Climatotherapy
Michael Brandwein, Garold Fuks, Avigail Israel, Ashraf Al-Ashhab, Deborah Nejman, Ravid Straussman, Emmilia Hodak, Marco Harari, Doron Steinberg, Zvi Bentwich, Noam Shental, Shiri Meshner
Dead Sea climatotherapy (DSC) is a therapeutic modality for a variety of chronic skin conditions, yet there has been scarce research on the relationship between the cutaneous microbiota and disease states in response to DSC. We characterized the skin bacterial and fungal microbiome of healthy volunteers who underwent DSC. Bacterial community diversity remained similar before and after treatment, w ...
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SPECIAL REPORT
Granuloma Faciale Treatment: A Systematic Review
Claudia Lindhaus, Peter Elsner
Granuloma faciale is an uncommon benign chronic dermatosis characterized by reddish-brown to violaceous asymptomatic plaques appearing predominantly on the face. The pathogenesis of granuloma faciale remains unclear, and it is frequently unresponsive to therapy. This systematic review aims to summarize all recent publications on the management of granuloma faciale. The publications are mainly indi ...
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SHORT COMMUNICATION
Predominant Contribution of CD4 T Cells to Human Herpesvirus 6 (HHV-6) Load in the Peripheral Blood of Patients with Drug-induced Hypersensitivity Syndrome and Persistent HHV-6 Infection
Fumi Miyagawa, Yuki Nakamura, Rie Ommori, Kazuya Miyashita, Hiroshi Iioka, Natsuki Miyashita, Mitsuko Nishikawa, Yukiko Himuro, Kohei Ogawa, Hideo Asada
Abstract is missing (Short communication)
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QUIZ
Six-month History of a Split Thumbnail: A Quiz
Yosuke Mai, Hideyuki Ujiie, Takashi Anan, Hajime Miyazawa, Keisuke Imafuku, Kokichi Hamasaka, Hiroshi Shimizu
Abstract is missing (Quiz)
Abstract  PDF
SHORT COMMUNICATION
9q22.3 Microdeletion Syndrome with Multiple Basal Cell Carcinomas Treated with Vismodegib: Three Key Messages in One Patient
Alice Kieny, Valérie Kremer, Sophie Scheidecker, Dan Lipsker
Abstract is missing (Short communication)
Abstract  PDF
CLINICAL REPORT
Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies
Manuel P. Pereira, Hannah Lüling, Annette Dieckhöfer, Sabine Steinke, Claudia Zeidler, Sonja Ständer
Brachioradial pruritus (BRP) and notalgia paraesthetica (NP) represent 2 of the most common neuropathic itch syndromes. A total of 58 consecutive patients presenting at the Center for Chronic Pruritus, University Hospital Münster, were analysed with regard to clinical presentation, anatomical and morphological pathologies, impairment in quality of life, and response to treatment with topical caps ...
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SHORT COMMUNICATION
Extensive Eruptive Syringoma After Liver Transplantation
Takuya Maeda, Ken Natsuga, Wataru Nishie, Kenichiro Yamashita, Hiroshi Shimizu
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
Kiyoko Yamada, Kenji Matsushita, Jingshu Wang, Takuro Kanekura
Atopic dermatitis (AD) is a chronic inflammatory skin disease. Corticosteroids, which are widely used for AD treatment, have adverse effects, and alternative treatments are urgently needed. This study examined the effect of topical application of high-dose glucose on inflamed skin in a murine model of AD. High-dose glucose treatment on the ear reduced dermatitis scores and ear thicknesses in mite ...
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QUIZ
Disseminated Vesicular Rash in an Immunocompetent Adult Woman: A Quiz
Trine Høgsberg, Anette Bygum
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Assessment of Quality of Life in Chronic Pruritus: Relationship Between ItchyQoL and Dermatological Life Quality Index in 1,150 Patients
Astrid Stumpf, Bettina Pfleiderer, Fleur Fritz, Nadi Osada, Suephy C. Chen, Sonja Ständer
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Validation of Pruritus Measures Gathered with the Electronic Patient-reported Outcome System MoPat
Michael Storck, Claudia Zeidler, Mirjam Rehr, Claudia Riepe, Martin Dugas, Sonja Ständer, Iñaki Soto-Rey
In order to improve diagnosis and treatment, physicians require information about the social context and quality of life of their patients. The Center for Chronic Pruritus at the University Hospital Münster achieves this goal using the electronic patient-reported outcome system "Mobile Patient Survey", which assesses pruritus and quality of life measures. The aim of this study is to evaluate the ...
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SHORT COMMUNICATION
Primary Cutaneous CD30+ Lymphoproliferative Disorders in a Patient with Severe Atopic Dermatitis: Is There a Causative Link?
Magdalena Zychowska, Zdzisław Woźniak, Joanna Maj
Abstract is missing (Short communication)
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CORRESPONDENCE
Psoriasis is More Prevalent than Indicated by Egeberg et al.’s Danish Study: A Comment
Petter Gjersvik
Abstract is missing (Correspondence)
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SHORT COMMUNICATION
Successful Treatment of Epidermal Nevus-Associated Pruritus with Topical Ketamine-Amitriptyline-Lidocaine
Jose A. Jaller, Gil Yosipovitch
Abstract is missing (Short communication)
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REVIEW
Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis
Kazuhisa Furue, Kazuhiko Yamamura, Gaku Tsuji, Chikage Mitoma, Hiroshi Uchi, Takeshi Nakahara, Makiko Kido-Nakahara, Takafumi Kadono, Masutaka Furue
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these disorders. Recently, functional activation of the IL-36 receptor (IL-36R) was discovered to be another driving force in the pathogenesis of psoriasis. ...
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INVESTIGATIVE REPORT
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966
Suvi-Päivikki Sinikumpu, Laura Huilaja, Juha Auvinen, Jari Jokelainen, Katri Puukka, Aimo Ruokonen, Markku Timonen, Kaisa Tasanen
Low grade inflammation is associated with many noncommunicable diseases. The association between skin diseases in general and systemic inflammation has not previously been studied at the population level. A whole-body investigation on 1,930 adults belonging to Northern Finland Birth Cohort 1966 was performed and high sensitive C-reactive protein (CRP) level was measured as a marker of low grade in ...
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INVESTIGATIVE REPORT
Long-term Impact of Ixekizumab on Psoriasis Itch Severity: Results From a Phase III Clinical Trial and Long-term Extension
Alexandra B. Kimball, Thomas Luger, Alice Gottlieb, Luis Puig, Roland Kaufmann, Russel Burge, Chen-Yen Lin, Gil Yosipovitch
Itching is a prevalent plaque psoriasis symptom. Ixekizumab, an IL-17A antagonist, has demonstrated rapid, significant improvements in itch severity over 12 weeks in Phase III psoriasis trials (UNCOVER-1, UNCOVER-2). We assessed the long-term (through 60 weeks) effect of ixekizumab maintenance therapy (80-mg ixekizumab every 4 weeks [IXEQ4W]) on itch severity, using the Itch Numeric Rating Scale, ...
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INVESTIGATIVE REPORT
Eczema in Psoriatico: An Important Differential Diagnosis Between Chronic Allergic Contact Dermatitis and Psoriasis in Palmoplantar Localization
Malgorzata Kolesnik, Ingolf Franke, Anke Lux, Sven R. Quist, Harald P. Gollnick
Differential diagnosis of palmoplantar non-pustular psoriasis and chronic allergic contact dermatitis (ACD) and the combination of these conditions, termed "eczema in psoriatico" (EIP), is difficult, especially in cases of isolated involvement. A blind re-evaluation of 63 archived formalin-fixed palmoplantar samples, previously diagnosed clinically as either psoriasis or chronic ACD, was performed ...
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QUIZ
Crusted Nodules on the Lower Left Arm in a Traveller Returning from South America: A Quiz
Ugur Uslu, Michael Erdmann, Stefan Schliep, Michael Sticherling
Abstract is missing (Quiz)
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CLINICAL REPORT
Clinical Characteristics of Pruritus and Pain in Patients with Hidradenitis Suppurativa
Łukasz Matusiak, Justyna Szczęch, Karolina Kaaz, Edyta Lelonek, Jacek C. Szepietowski
A growing body of research has indicated that pruritus is an important feature of hidradenitis suppurativa (HS). This study evaluated pruritus and pain among 103 patients with HS. Pruritus and pain intensity were assessed with a visual analogue scale, numerical rating scale and 4-item Itch Questionnaire. Dermatology Life Quality Index (DLQI) was implemented to assess quality of life (QoL) issues. ...
Abstract  PDF
CLINICAL REPORT
Role of Substance P and Its Receptor Neurokinin 1 in Chronic Prurigo: a Randomized, Proof-of-Concept, Controlled Trial with Topical Aprepitant
Tatevik Ohanyan, Nicole Schoepke, Stefan Eirefelt, Gert Hoey, Witte Koopmann, Tomasz Hawro, Marcus Maurer, Martin Metz
Substance P (SP) and its receptor neurokinin 1 (NK1R) are thought to be involved in the pathogenesis of chronic prurigo. Here, we assessed SP serum levels, cutaneous NK1R expression, and the effects of topical aprepitant, an NK1R antagonist, in patients with chronic prurigo. SP and NK1R were increased, compared with controls, in the serum and in lesional vs. non-lesional skin of the patients, resp ...
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SHORT COMMUNICATION
Staphylococcal Scalded Skin Syndrome Caused by a Rare Variant of Exfoliative-toxin-A + S. aureus in an Adult Immunocompromised Woman
Simona Saluzzo, Franziska Layer, Georg Stingl, Georg Stary
Abstract is missing (Short communication)
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CLINICAL REPORT
Psychological Health Status and Health-related Quality of Life in Adults with Atopic Dermatitis: A Nationwide Cross-sectional Study in South Korea
Sul Hee Lee, Si Hyung Lee, Sung Yul Lee, Bora Lee, Sang-Hoon Lee, Young Lip Park
Atopic dermatitis (AD) is a chronic inflammatory skin disorder. Patients with AD often experience psychological distress and poor health-related quality of life (HRQoL). The aim of this study was to investigate the association of several psychological health statuses and poor HRQoL in an adult population with AD in South Korea. A total of 37,578 adults who participated in the Korean National Healt ...
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SHORT COMMUNICATION
Successful Treatment of Severe Recalcitrant Hidradenitis Suppurativa with the Interleukin-17A Antibody Secukinumab
Anna Schuch, Tatjana Fischer, Alexander Boehner, Tilo Biedermann, Thomas Volz
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Locally Aggressive Trichoblastic Tumours (Low-grade Trichoblastic Carcinomas): Clinicopathological Analysis and Follow-up
Camille Hua, Charles Velter, Amelie Osio, Céleste Lebbe, Nicole Basset-Seguin, Bernard Cribier, Maxime Battistella
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Photodynamic Therapy: Influence of Clinical and Procedure Variables on Treatment Response in Basal Cell Carcinoma and Bowen Disease
Tamara Gracia-Cazaña, Marta Mascaraque, Nerea Salazar, Jesús Vera-Álvarez, María Pilar Frías, Salvador González, Ángeles Juarranz, Yolanda Gilaberte
Abstract is missing (Short communication)
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CLINICAL REPORT
Distinct Patterns and Aetiology of Chromonychia
Soo Hyeon Bae, Min Young Lee, Jee-Bum Lee
Abnormal colouring of the nails may be a sign of underlying systemic or local disorders. This study investigated the prevalence and causes of chromonychia as a whole, as well as of each subtype. Among 163 patients with chromonychia, trauma was the pathogenesis in up to 20.9% (34/163) of cases. The most common subtype was melanonychia (54.0%; 88/163), followed by leukonychia (23.9%), red (8.6%), gr ...
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SHORT COMMUNICATION
Dermatofibrosarcoma Protuberans Presenting as a Large Atrophic Plaque on the Chest
Ryosuke Saigusa, Takuya Miyagawa, Satoshi Toyama, Jun Omatsu, Tomomitsu Miyagaki, Yuri Masui, Daisuke Yamada, Shinichi Sato
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Adult Staphylococcal Scalded Skin Syndrome Successfully Treated with Multimodal Therapy Including Intravenous Immunoglobulin
Toru Urata, Michihiro Kono, Yuka Ishihara, Masashi Akiyama
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Pre-emptive Evaluation of Venom Allergy in a Patient with Systemic Mastocytosis
Theo Gülen, Cem Akin
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Clinical Characteristics of the Halo Phenomenon in Infants with Neurofibromatosis 1: A Case Series
Monji Koga, Yuichi Yoshida, Shinichi Imafuku
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Dystrophic Calcification in a Patient with Primary Localized Cutaneous Nodular Amyloidosis: An Uncommon Ultrasound Finding
Sergi Planas-Ciudad, Esther Roé Crespo, Juan Francisco Mir-Bonafé, Fania Zamantta Muñoz-Garza, Luis Puig
Abstract is missing (Short communication)
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CORRESPONDENCE
Differential Diagnosis of Erythema Multiforme in Childhood: A Comment to Siedner-Weintraub et al.
Gregorio P. Milani, Sebastiano A.G. Lava, Mario G. Bianchetti
Abstract is missing (Correspondence)
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QUIZ
Long-standing Verrucous Plaques on the Buttocks: A Quiz
Dong Hyuk Eun, Jun Young Kim, Yoon Hyuk Choi, Yong Hyun Jang
Abstract is missing (Quiz)
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CLINICAL REPORT
Evaluation of a Rapid, Fully Automated Platform for Detection of BRAF and NRAS Mutations in Melanoma
Fanny Barel, Briac Guibourg, Laetitia Lambros, Glen Le Flahec, Pascale Marcorelles, Arnaud Uguen
BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration. We compared the rapid, real-time, fully automated molecular diagnosis platform Idylla™ with next-generation sequencing (NGS) and immunohistochemistry for detection of BRAF and NRAS mutations in 36 patients with metastatic melanomas. The Idyl ...
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SHORT COMMUNICATION
Bowen’s Disease: Long-term Results of Treatment with 5-Fluorouracil Cream, Photodynamic Therapy or Surgical Excision
Maud Henriette Elisabeth Jansen, Diebrecht Appelen, Patty J. Nelemans, Veronique J. Winnepenninckx, Nicole W.J. Kelleners-Smeets, Klara Mosterd
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Multiple Basal Cell Carcinoma Arising in a Verrucous Epidermal Naevus: Clinical, Histological and Therapeutic Observations
Francesca Satolli, Miriam Rovesti, Maria Beatrice De Felici, Alfredo Zucchi, Calogero Pagliarello, Claudio Feliciani
Abstract is missing (Short communication)
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QUIZ
Dome-shaped Papules on the Left Flank: A Quiz
Sophie Roenneberg, Ivan Hegyi, Werner Kempf, Katrin Kerl, Emmanuella Guenova
Abstract is missing (Quiz)
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INVESTIGATIVE REPORT
Agreeableness as Predictor of Induced Scratching in Patients with Atopic Dermatitis: A Replication Study
Christina Schut, Katharina Reinisch, Alexander Classen, Sarah Andres, Uwe Gieler, Jörg Kupfer
In patients with atopic dermatitis agreeableness and public self-consciousness have previously been shown to be significant predictors of induced scratching, while depression was significantly related to induced itch. This study aimed to replicate these findings. Itch and scratching were induced by videos of crawling insects or skin diseases. Induced itch was measured using a visual analogue scale ...
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INVESTIGATIVE REPORT
Epidemiology and Outcome of Squamous Cell Carcinoma in Epidermolysis Bullosa in Australia and New Zealand
Minhee Kim, Minmin Li, Lizbeth R.A. Intong-Wheeler, Kim Tran, Damian Marucci, Dedee F. Murrell
We investigate the epidemiology and outcomes of squamous cell carcinoma (SCC) in recessive dystrophic epidermolysis bullosa (RDEB) from the Australasian EB registry cohort. Seventeen out of 49 (34.6%) RDEB patients developed at least one SCC. Data detailing SCC was obtainable from 16/17 RDEB-SCC patients. A total number of 161 primary SCCs occurred in 16 RDEB-SCC patients with a mean of 10 SCCs pe ...
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SHORT COMMUNICATION
Need for Improved Definition of ”Chronic Wounds” in Clinical Studies
Bhone Myint Kyaw, Krister Järbrink, Laura Martinengo, Josip Car, Keith Harding, Artur Schmidtchen
Abstract is missing (Short communication)
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CLINICAL REPORT
Hyperhidrosis Substantially Reduces Quality of Life in Children: A Retrospective Study Describing Symptoms, Consequences and Treatment with Botulinum Toxin
Sandra Eriksson Mirkovic, Alma Rystedt, Mie Balling, Carl Swartling
Studies on children with hyperhidrosis are sparse. This retrospective study presents clinical data and quality of life, along with treatment effect and safety of botulinum toxin (BTX). Case reports from 366 children were included to capture the medical history of hyperhidrosis. The total median score of the Dermatology Life Quality Index before treatment was 11 for children aged 16–17 years and ...
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SHORT COMMUNICATION
Epstein-Barr Virus-related Acute Genital Ulcer Successfully Treated with Colchicine
Agathe Nouchi, Gentiane Monsel, Barthélémy Lafon-Desmurs, Laurence Meng, Sonia Burrel, Micheline Moyal-Barracco, Eric Caumes
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Ichthyosis with Confetti Inherited from a Mosaic Father
Kristine A.U. Pallesen, Ole Clemmensen, Judith Fischer, Jens Michael Hertz, Anette Bygum
Abstract is missing (Short communication)
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CLINICAL REPORT
Incidence and Regression of Actinic Keratoses in Organ Transplant Recipients
Zainab Jiyad, Louise Marquart, Peter O'Rourke, Adèle C. Green
Actinic keratoses (AKs) are highly dynamic lesions and AK activity has been shown to be associated with squamous cell carcinoma (SCC). We sought to explore risk factors which may affect the 12-month turnover of AKs in organ transplant recipients (OTRs). The number of incident AKs, regressed AKs and net change in AK counts were calculated. Negative binomial regression and Poisson regression models ...
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SHORT COMMUNICATION
Primary Cutaneous Aggressive Epidermotropic CD8+ T-cell Lymphoma with Brain Involvement and Mimicking Dermatomyositis
Hitoshi Terui, Kenshi Yamasaki, Saaya Yoshida, Setsuya Aiba
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Rasch Analysis of the Dermatology Life Quality Index Reveals Limited Application to Chinese Patients with Skin Disease
Zehui He, Riccardo Lo Martire, Chuanjian Lu, Hongxia Liu, Lin Ma, Ying Huang, Yongmei Li, Liyun Sun, Yanping Bai, Wali Liu, Xushan Zha
The objective of this study was to examine the psychometric properties of the Chinese version of the Dermatology Life Quality Index (DLQI) and to assess the invariance of its items with respect to several patient parameters via Rasch analysis. Data were aggregated from 9,845 patients with various skin diseases across 9 hospitals in different regions of China. The response structure, local independ ...
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SHORT COMMUNICATION
Light Chain Deposition Disease with Bullous Skin Lesions Mimicking Atypical Bullous Pemphigoid
Marion Malphettes, Pauline Bonnet, Pierre Schneider, Marguerite Vignon, Marine Baron, Jean-David Bouaziz, Maxime Battistella
Abstract is missing (Short communication)
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BOOK REVIEW
Therapy for Severe Psoriasis, 1st Edition
Lone Skov
Abstract is missing (Book review)
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IN THIS ISSUE
Comment on: Quimp: A word meaning “quality of life impairment”
Pavel V. Chernyshov
Abstract is missing (In this Issue...)
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IN THIS ISSUE
Have you measured the patient’s quimp?
Magnus Lindberg
Abstract is missing (In this Issue...)
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BOOK REVIEW
Neonatal and Infant Dermatology, 3rd edition
Regina Fölster-Holst
Abstract is missing (Book review)
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