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Preview of fully accepted papers, still not published in any volume

SHORT COMMUNICATION
Allogeneic Haematopoietic Cell Transplantation for Epidermolysis Bullosa: the Dutch Experience
Katarzyna B. Gostyńska, Vamsi K. Yenamandra, Caroline Lindemans, José Duipmans, Antoni Gostyński, Marcel F. Jonkman, Jaap-Jan Boelens
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Characteristics of Pruritus in Relation to Self-assessed Severity of Atopic Dermatitis
Flavien Huet, Marie-Sarah Faffa, Florence Poizeau, Stéphanie Merhand, Laurent Misery, Emilie Brenaut
The objective of this study was to explore characteristics of pruritus in atopic dermatitis (AD) in relation to the severity of AD. A web-questionnaire was used, which included the Patient-Oriented SCORing Atopic Dermatitis index, the 5-D itch scale and the Brest questionnaire. A total of 170 participants were included (86.5% women, mean age 30.9 years). Severity of AD was mild for 8.2% of patient ...
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INVESTIGATIVE REPORT
Changes in Lesional and Non-lesional Skin Microbiome During Treatment of Atopic Dermatitis
Sunyoung Kwon, Ji Young Choi, Jung-Won Shin, Chang-Hun Huh, Kyoung-Chan Park, Mi-Hee Du, Sungroh Yoon, Jung-Im Na
The aim of this study was to evaluate changes in the skin surface microbiome in patients with atopic dermatitis during treatment. The effect of narrowband ultraviolet B phototherapy was also studied to determine the influence of exposure to ultraviolet. A total of 18 patients with atopic dermatitis were included in the study. Patients were divided into 2 groups based on treatment: 1 group treated ...
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REVIEW
Use of Anti-transcriptional Intermediary Factor-1 Gamma Autoantibody in Identifying Adult Dermatomyositis Patients with Cancer: A Systematic Review and Meta-analysis
Marion Best, Nicolas Molinari, François Chasset, Thierry Vincent, Nadège Cordel, Didier Bessis
Anti-transcriptional intermediary factor-1γ (TIF-1γ) autoantibody may be associated with cancer in adult patients with dermatomyositis. The aim of this study was to evaluate the risk of cancer in the presence of anti-TIF-1γ autoantibody in adult dermatomyositis. A comprehensive database search of EMBASE, MEDLINE and the Cochrane Library up to May 2018 was performed using the main key words “d ...
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SHORT COMMUNICATION
Combination of Surgery and Nd:YAG Laser Therapy for Recalcitrant Viral Warts: A Successful Therapeutic Approach for Immunosuppressed Patients
Andrea Baczako, Veronika Krautheim, Tilo Biedermann, Thomas Volz
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Treatment-Induced Delusions of Infestation Associated with Increased Brain Dopamine Levels
Emilie Fowler, Andrea Maderal, Gil Yosipovitch
Abstract is missing (Short communication)
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CLINICAL REPORT
Psoriasis as a Predictor of Cardiometabolic Comorbidity in Women: A Study Based on the Danish National Birth Cohort
Christoffer Blegvad, Anne-Marie Nybo Andersen, Abdulfatah Adam, Claus Zachariae, Lone Skov
Psoriasis is associated with cardiometabolic comorbidity; however, whether this is due to common lifestyle-related risk factors is unclear. This study investigated the association between psoriasis and cardiometabolic comorbidity, taking body mass index and smoking into account. The population comprised expectant mothers in the Danish National Birth Cohort (established 1996–2002). During pregnan ...
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SHORT COMMUNICATION
A Case of Aplasia Cutis Congenita with Widespread Multifocal Skin Defects Without Extracutaneous Abnormalities
Jemin Kim, Jihee Kim, Myeongseob Lee, Eui Ra Huh, Joohee Lim, Kook In Park, Sang Ho Oh
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Exploratory Study of Intracutaneous Histamine Stimulation in Patient Populations with Chronic Pruritus
Athanasios Tsianakas, Nadine Nippe, Christina Maria Hamper, Anna Friederike Cordes, Claudia Zeidler, Martin Schmelz, Sonja Ständer
Chronic pruritus can be a diagnostic sign of an underlying disease. In the intracutaneous histamine test, histamine (one of the best-known inducers of pruritus) may cause different reaction patterns depending on the underlying disease. The aim of this study was to determine if an intracutaneous injection of histamine can differentiate between the causes of chronic pruritus and thus be used as a di ...
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INVESTIGATIVE REPORT
Socioeconomic Status and the Prevalence of Skin and Atopic Diseases in Five European Countries
Robert F. Ofenloch, Marie Louise A. Schuttelaar, Åke Svensson, Magnus Bruze, Luigi Naldi, Simone Cazzaniga, Peter Elsner, Margarida Gonçalo, Thomas L. Diepgen
The aim of this study was to investigate the association between socioeconomic status and the prevalence of self-reported skin and atopic diseases in the general population of 5 European countries. A random sample was drawn from the general population aged 18–74 years, based on electoral precincts. Socioeconomic status was estimated by combining net household income with the highest education of ...
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SHORT COMMUNICATION
Acrokeratosis Paraneoplastica-like Findings as a Manifestation of Systemic Lupus Erythematosus
Laura Huilaja, Minna Soronen, Anna Karjalainen, Kaisa Tasanen
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Paraneoplastic Opsoclonus-Myoclonus Syndrome Preceding a Mucosal Malignant Melanoma
Flora Dresco, François Aubin, Elise Deveza, Eugeniu Revenco, Laurent Tavernier, Eve Puzenat
Abstract is missing (Short Communication)
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SHORT COMMUNICATION
High Blood Pressure in Normal-weight Children with Psoriasis
Francesca Caroppo, Laura Ventura, Anna Belloni Fortina
Abstract is missing (Short communication)
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REVIEW
Effect of Diet in Chronic Spontaneous Urticaria: A Systematic Review
Hélène Cornillier, Bruno Giraudeau, Mahtab Samimi, Stéphane Munck, Florence Hacard, Annie-Pierre Jonville-Bera, Marie-Hélène Jegou, Gwenaëlle d'Acremont, Bach-nga Pham, Olivier Chosidow, Annabel Maruani
Strategies for diets in chronic spontaneous urticaria (CSU) are controversial. This systematic review assessed the interest in diet for managing CSU. We searched for original reports in MEDLINE, EMBASE, CENTRAL and LILACS. Among the 278 reports screened, 20 were included, involving 1,734 patients. Reports described 3 types of systematic diet: pseudoallergen-free diet (n = 1,555 patients), low- ...
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REVIEW
Digital Education for Health Professions in the Field of Dermatology: A Systematic Review by Digital Health Education Collaboration
Xiaomeng Xu, Pawel Przemyslaw Posadzki, Grace E. Lee, Josip Car, Helen Elizabeth Smith
Digital health education is a new approach that is receiving increasing attention with advantages such as scalability and flexibility of education. This study employed a Cochrane review approach to assess the evidence for the effectiveness of health professions’ digital education in dermatology to improve knowledge, skills, attitudes and satisfaction. Twelve trials (n = 955 health profession ...
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INVESTIGATIVE REPORT
Early Circulating Tumour DNA Variations Predict Tumour Response in Melanoma Patients Treated with Immunotherapy
Laura Keller, Nicolas Guibert, Anne Casanova, Stephanie Brayer, Magali Farella, Myriam Delaunay, Julia Gilhodes, Elodie Martin, Gisèle Balagué, Gilles Favre, Anne Pradines, Nicolas Meyer
Antibodies targeting immune checkpoints were recently approved for metastatic melanoma. However, not all patients will respond to the treatment and some will experience grade III–IV immune-related adverse events. Therefore, early identification of non-responder patients would greatly aid clinical practice. Detection of circulating tumour DNA (ctDNA) is a non-invasive approach to monitor tumour r ...
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SHORT COMMUNICATION
Keratin Gel as an Adjuvant in the Treatment of Recalcitrant Pyoderma Gangrenosum Ulcers: A Case Report
Evy Paulsen, Anette Bygum
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Measuring Patient Needs and Benefits in Dermatology using the Patient Benefit Index 2.0: A Validation Study
Janine Topp, Matthias Augustin, Kathrin von Usslar, Ramona Gosau, Kristian Reich, Michael Reusch, Christine Blome
This study investigated the validity and feasibility of the Patient Benefit Index 2.0 (PBI 2.0), a short instrument to assess patient-relevant treatment benefit. In a cross-sectional study, patients with skin diseases completed the PBI 2.0 alongside instruments on quality of life and disease-specific PBI long versions to assess convergent validity. Feasibility questions appraise comprehensibility, ...
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INVESTIGATIVE REPORT
Staphylococcus epidermidis-induced Interleukin-1 Beta and Human Beta-defensin-2 Expression in Human Keratinocytes is Regulated by the Host Molecule A20 (TNFAIP3)
Maren Simanski, Anna-Sophie Erkens, Franziska Rademacher, Jürgen Harder
Staphylococcus epidermidis is an abundant skin commensal capable of activating cutaneous defense responses, such as induction of cytokines and antimicrobial peptides. To permanently colonize human skin and prevent inflammation S. epidermidis needs to control the induction of host defense mediators. We report here that S. epidermidis induces expression of the host regulator protein A20 in human ker ...
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SHORT COMMUNICATION
A Case of Generalized Interstitial Granuloma Annulare and Arthritis Associated with Breast Cancer
Ariane Clapé, Clélia Vanhaecke, Anne Durlach, Philippe Bernard, Christelle Jouannaud, Laurie Kpodar, Bernard Cribier, Manuelle Viguier
Abstract is missing (Short Communication)
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SHORT COMMUNICATION
Aberrant B-cell Subsets and Immunoglobulin Levels in Patients with Moderate-to-severe Psoriasis
Katrin Kahlert, Franziska Grän, Khalid Muhammad, Sandrine Benoit, Edgar Serfling, Matthias Goebeler, Andreas Kerstan
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Pulse–Daylight–Photodynamic Therapy in Combination with Corticosteroid and Brimonidine Tartrate for Multiple Actinic Keratoses: A Randomized Clinical Trial
Stine R. Wiegell, Urs B. Johansen, Hans Christian Wulf
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Large-scale Retrospective Cohort Study of Psychological Stress in Patients with Alopecia Areata According to the Frequency of Intralesional Steroid Injection
Shinwon Hwang, Jaeyong Shin, Tae-Gyun Kim, Do-Young Kim, Sang Ho Oh
Abstract is missing (Short communication)
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CLINICAL REPORT
Increase in Vitamin D but not Regulatory T Cells following Ultraviolet B Phototherapy of Patients with Atopic Dermatitis
Stine Simonsen, Charlotte M. Bonefeld, Jacob P. Thyssen, Carsten Geisler, Lone Skov
This study investigated serum 25-hydroxyvitamin D (25(OH)D) concentrations and circulating regulatory T cells in patients with atopic dermatitis receiving narrow-band ultraviolet B (nbUVB) phototherapy. Thirty adult patients with atopic dermatitis were included. Blood samples were collected at baseline and at weeks 2 and 4 of nbUVB phototherapy. Skin biopsies were taken at baseline and at week 4. ...
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INVESTIGATIVE REPORT
Effects of Short-term Temperature Change in the Innocuous Range on Histaminergic and Non-histaminergic Acute Itch
Zoe Lewis, David N. George, Fiona Cowdell, Henning Holle
While temperatures in the noxious range are well-known to inhibit acute itch, the impact of temperature in the innocuous temperature range is less well understood. We investigated the effect of alternating short-term temperature changes in the innocuous range on histamine and cowhage-induced acute itch, taking into account individual differences in baseline skin temperature and sensory thresholds. ...
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SHORT COMMUNICATION
Phenotypic Features of Epidermolysis Bullosa Simplex due to KLHL24 Mutations in 3 Italian Cases
May El Hachem, Sabina Barresi, Andrea Diociaiuti, Renata Boldrini, Angelo Giuseppe Condorelli, Ettore Capoluongo, Vittoria Proto, Giulietta Scuvera, Cristina Has, Marco Tartaglia, Daniele Castiglia
Abstract is missing (Short Communication)
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CLINICAL REPORT
The Importance of Achieving Clear or Almost Clear Skin for Patients: Results from the Nordic Countries of the Global "Clear about Psoriasis" Patient Survey
Mads Kirchheiner Rasmussen, Martin Enger, Anna-Karin Dahlborn, Siri Juvik, Laura Fagerhed, Rikke Dodge, Charlotta Enerbäck
Psoriasis is a stigmatizing chronic skin condition in which impairment of quality of life is associated with visibility of skin lesions, disease activity and severity. The ultimate goal of treatment is complete clearance of skin symptoms. The worldwide “Clear About Psoriasis” survey explored patients’ perspectives on clear/almost clear skin and the impact of psoriasis on daily life. We repor ...
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SHORT COMMUNICATION
Induced Vitiligo due to Talimogene Laherparepvec Injection for Metastatic Melanoma Associated with Long-term Complete Response
Pablo Iglesias, Simone Ribero, Alicia Barreiro, Sebastian Podlipnik, Cristina Carrera, Josep Malvehy, Susana Puig
Abstract is missing (Short Communication)
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CLINICAL REPORT
Influence of Itch and Pain on Sleep Quality in Atopic Dermatitis and Psoriasis
Karolina Kaaz, Jacek C. Szepietowski, Łukasz Matusiak
Subjective symptoms accompanying atopic dermatitis and psoriasis can negatively influence patients’ well-being. This study assessed the impact of itch and pain on sleep quality among 100 patients with atopic dermatitis and 100 patients with psoriasis, compared with 50 controls. The Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate a spectrum of sleep dis ...
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CLINICAL REPORT
Prevalence and Clinical Characteristics of Cutaneous Manifestations Associated with Bacteraemia: A Cross-sectional Prospective Study
Hélène Taquin, Thomas Hubiche, Laurent Roudière, Agnès Fribourg, Pascal Del Giudice
Bacteraemias are life-threatening conditions that require rapid care and antibiotherapy. Dermatological signs might help in deciding the most relevant treatment. The aim of this study was to determine the prevalence and clinical characteristics of cutaneous manifestations in hospitalized patients with bacteraemia. A cross-sectional study was conducted over a period of 1 year. All consecutive patie ...
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SHORT COMMUNICATION
Blaschkolinear Lichen Planus Pigmentosus in the Setting of Chronic Graft-versus-host Disease
Caterina Pinzani, Jean-David Bouaziz
Abstract is missing (Short communication)
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CLINICAL REPORT
Nail Involvement as a Predictor of Disease Severity in Paediatric Psoriasis: Follow-up Data from the Dutch ChildCAPTURE Registry
Inge M.G.J. Bronckers, Finola M. Bruins, Maartje J. van Geel, Hans M.M. Groenewoud, Wietske Kievit, Peter C.M. van de Kerkhof, Marcel C. Pasch, Elke M.G.J. de Jong, Marieke M.B. Seyger
Little is known about the relationship between nail psoriasis and psoriasis severity in children, and there has been no longitudinal assessment of psoriasis severity related to nail psoriasis. The aim of this study was to assess whether nail psoriasis could serve as a predictor for a more severe disease course. De-identified data were obtained from the ChildCAPTURE registry, a daily clinical pract ...
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SHORT COMMUNICATION
Porokeratosis Ptychotropica on the Penis and Scrotum: A Case Report
Yue-Tong Qian, Sergio Vano-Galvan, Jia-Wei Liu, Wei Liu, Dong-Lai Ma
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Assessing Punctate Administration of Beta-alanine as a Potential Human Model of Non-histaminergic Itch
Janne D. Christensen, Silvia Lo Vecchio, Jesper Elberling, Lars Arendt-Nielsen, Hjalte H. Andersen
Abstract is missing (Short communication)
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QUIZ
Rashes, Erosions and Purulent Fluid in the Intertriginous Areas: A Quiz
Yonghu Sun, Furen Zhang
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Perception of Dermatology and Dermatologists Among Medical Students
Laine Ludriksone, Jörg Tittelbach, Peter Elsner
Abstract is missing (Short Communication)
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SHORT COMMUNICATION
Skin Lesions Suggesting Type 2 Segmental Mosaicism in Noonan Syndrome
Rudolf Happle
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
The Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization
Lorenzo Pasquali, Ankit Srivastava, Florian Meisgen, Kunal Das Mahapatra, Ping Xia, Ning Xu Landén, Andor Pivarcsi, Enikö Sonkoly
Psoriasis is a common immune-mediated disease resulting from altered cross-talk between keratinocytes and immune cells. Previous transcriptomic studies have identified thousands of deregulated genes in psoriasis skin; however, the transcriptomic changes confined to the epidermal compartment remained poorly characterized. The aim of this study was to characterize the transcriptomic landscape of pso ...
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QUIZ
Fast-growing Painful Leg Ulcers in a 26-year-old Woman with Systemic Lupus Erythematosus: A Quiz
Julia Hartmann, Holger A. Haenssle, Alexander H. Enk, Ferdinand Toberer
Abstract is missing (Quiz)
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CLINICAL REPORT
Occurrence, Chronicity and Intensity of Itch in a Clinical Consecutive Sample of Patients with Skin Diseases: a Multi-centre Study in 13 European Countries
Christina Schut, Florence J. Dalgard, Jon Anders Halvorsen, Uwe Gieler, Lars Lien, Lucía Tomas Aragones, Françoise Poot, Gregor B. E. Jemec, Laurent Misery, Lajos Kemény, Francesca Sampogna, Henriët van Middendorp, Flora Balieva, Dennis Linder, Jacek C. Szepietowski, Andrey Lvov, Servando E. Marron, Ilknur K. Altunay, Andrew Y. Finlay, Sam Salek, Jörg Kupfer
Itch is an unpleasant symptom, affecting many dermatological patients. Studies investigating the occurrence and intensity of itch in dermatological patients often focus on a single skin disease and omit a control group with healthy skin. The aim of this multi-centre study was to assess the occurrence, chronicity and intensity (visual analogue scale 0–10) of itch in patients with different skin d ...
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SHORT COMMUNICATION
Unmet Needs in Pemphigoid Diseases: An International Survey Amongst Patients, Clinicians and Researchers
Aniek Lamberts, Marc Yale, Sergei A. Grando, Barbara Horváth, Detlef Zillikens, Marcel F. Jonkman
Abstract is missing (Short communication)
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CLINICAL REPORT
Ultrasound Assessment of Psoriatic Onychopathy: A Cross-sectional Study Comparing Psoriatic Onychopathy with Onychomycosis
Mireia Moreno, Maria Pilar Lisbona, Fernando Gallardo, Gustavo Deza, Marta Ferran, Caridad Pontes, Jesús Luelmo, Joan Maymó, Jordi Gratacós
This cross-sectional study evaluated the usefulness of an ultrasound technique in assessment of nail changes in 35 patients with psoriatic onychopathy and 25 with nail dystrophy secondary to onychomycosis. All patients underwent 3 examinations: a complete clinical assessment; a nail ultrasound study; and fungal culture. Nails of patients with psoriatic onychopathy presented a thinner nail plate an ...
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SHORT COMMUNICATION
Pruritus in Chronic Liver Disease: A Questionnaire Survey on 216 Patients
Makiko Kido-Nakahara, Takeshi Nakahara, Norihiro Furusyo, Shinji Shimoda, Kazuhiro Kotoh, Masaki Kato, Jun Hayashi, Toshimasa Koyanagi, Masutaka Furue
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Two Cases of Acute Febrile Neutrophilic Dermatosis Thought to be Caused by Topical Clindamycin
Kiriko Nitta, Yoko Kano, Yukiko Ushigome, Jun Hayakawa, Tetsuo Shiohara
Abstract is missing (Short Communication)
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SHORT COMMUNICATION
A Case of Perforating Folliculitis Induced by Vemurafenib
Ken Shiraishi, Tae Masunaga, Mikiko Tohyama, Koji Sayama
Abstract is missing (Short Communication)
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CLINICAL REPORT
Fractional Ablative CO2 Laser Followed by Topical Application of Sodium Stibogluconate for Treatment of Active Cutaneous Leishmaniasis: A Randomized Controlled Trial
Ofir Artzi, Eli Sprecher, Amir Koren, Joseph N. Mehrabi, Oren Katz, Yuval Hilerowich
Conventional treatment of cutaneous leishmaniasis often leaves permanent scars with frequent psychosocial sequelae. The aim of this study was to compare the efficacy, safety, associated pain and final cosmetic outcome of fractional carbon dioxide (CO2) laser followed by topical application of sodium stibogluconate vs. sodium stibogluconate injections for the treatment of cutaneous leishmaniasis. A ...
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INVESTIGATIVE REPORT
Mortality in Patients with Bullous Pemphigoid: A Retrospective Cohort Study, Systematic Review and Meta-analysis
Khalaf Kridin, Wesal Shihade, Reuven Bergman
There is little consensus regarding mortality data in bullous pemphigoid (BP). The aim of this study was to evaluate mortality among a relatively large cohort of Israeli patients with BP and to perform a meta-analysis synthesizing existing data on 1-year mortality rates of patients with BP. This retrospective cohort study of 287 patients diagnosed with BP between 2000 and 2015 compared the mortali ...
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CLINICAL REPORT
Comparison of the Treatment Outcome of Oral Tofacitinib with Other Conventional Therapies in Refractory Alopecia Totalis and Universalis: A Retrospective Study
Jung-Won Shin, Chang-Hun Huh, Min-Woo Kim, Ji-Su Lee, Ohsang Kwon, Soyun Cho, Hyun-sun Park
Treatment of alopecia totalis and alopecia universalis is often challenging and unsatisfactory. Recently, Janus kinase inhibitor has shown promising results. The aim of this study is to compare the efficacy and tolerability of oral tofacitinib and conventional modalities for treating refractory alopecia totalis/universalis. A total of 74 patients (18 treated with tofacitinib, 26 treated with conve ...
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SHORT COMMUNICATION
Increase in FoxP3-positive Cells and Their Contacts with Mast Cells in Köbner-negative Patients with Psoriasis after Tape-stripping
Mireille-Maria Suttle, Riikka-Liisa Ritanen, Ilkka T. Harvima
Abstract is missing (Short communication)
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QUIZ
Rapidly Growing Tumour on the Forearm of an 83-year-old Woman: A Quiz
Chakib El Habnouni, Hélène Cornillier, Valérie Tauveron, Serge Guyetant, Annabel Maruani
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Schöpf-Schulz-Passarge Syndrome: Previously Unreported WNT10A Genotype and Phenotypes in 9 Family Members
Corinna E. Zimmermann, Muhidien Soufi, Volker Ruppert, Juergen R. Schaefer, Helmut von Domarus
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Intergluteal Contour Deformity in Hidradenitis Suppurativa
Maria Letizia Musumeci, Giulia Capuzzo, Barbara Cammisuli, Antonio Pesce, Giuseppe Micali
Abstract is missing (Short communication)
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QUIZ
Bizarre Pigmented Lesion on the Scalp: A Quiz
Giuseppe Micali, Anna Elisa Verzì, Elisabetta D'Agata, Francesco Lacarrubba
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Novel Compound Heterozygous Mutations in RAG1 in a Patient with Cutaneous Lymphoproliferative Disease
Cong-cong Xu, Zhi-ming Chen, Jing-shu Xiong, Hao Chen, Jian-Fang Sun
Abstract is missing (Short Communication
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SHORT COMMUNICATION
Evaluation of Single Nucleotide Variants in Ethiopian Patients with Atopic Dermatitis
Samina Asad, Isabel Tapia-Páez, Andrea Montano Montes, Carl-Fredrik Wahlgren, Carl-Fredrik Wahlgren, Kassahun D. Bilcha, Magnus Nordenskjöld, Maria Bradley
Abstract is missing (Short communication)
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CLINICAL REPORT
Direct Immunofluorescence of Mechanobullous Epidermolysis Bullosa Acquisita, Porphyria Cutanea Tarda and Pseudoporphyria
Heleen J. de Groot, Marcel F. Jonkman, Hendri H. Pas, Gilles F.H. Diercks
Mechanobullous epidermolysis bullosa acquisita (mEBA) can have a clinical presentation that is very similar to other blistering diseases, such as porphyria cutanea tarda (PCT) and pseudoporphyria. Direct immunofluorescence is an important feature in the diagnosis of mEBA, although features that overlap with PCT and pseudoporphyria have been reported. This retrospective observational study investig ...
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INVESTIGATIVE REPORT
Knowledge and Influence of Predatory Journals in Dermatology: A Pan-Austrian Survey
Georg Richtig, Markus Richtig, Wolfram Hoetzenecker, Werner Saxinger, Bernhard Lange-Asschenfeldt, Andreas Steiner, Robert Strohal, Christian Posch, Johann W. Bauer, Robert R. Müllegger, Teresa Deinlein, Norbert Sepp, Beatrix Volc-Platzer, Van Anh Nguyen, Matthias Schmuth, Christoph Hoeller, Gudrun Pregartner, Erika Richtig
The aim of this study was to assess the knowledge and influence of predatory journals in the field of dermatology in Austria. A total of 286 physicians (50.5% men) completed a questionnaire. The vast majority of subjects read scientific articles (n = 281, 98.3%) and took them into consideration in their clinical decision-making (n = 271, 98.5% of participants that regularly read scientific ...
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COMMENTARY
Predatory Journals in Dermatology: A Hidden Danger
Guy Shalom
Abstract is missing (Commentary)
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SHORT COMMUNICATION
Cytophagic Histiocytic Panniculitis Associated with Myelodysplastic Syndrome
Ryoko Kimura, Kazunari Sugita, Hiroyuki Goto, Osamu Yamamoto
Abstract is missing (Short Communication)
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CLINICAL REPORT
Rosacea and Demodicosis: Little-known Diagnostic Signs and Symptoms
Fabienne M.N. Forton, Viviane De Maertelaer
Papulopustular rosacea and demodicosis are characterized by non-specific symptoms, which can make clinical diagnosis difficult. This retrospective study of 844 patients assessed the diagnostic importance of clinical signs and symptoms that are poorly recognized as being associated with these conditions. In addition to well-known signs (vascular signs (present in 80% of patients), papules (39%), pu ...
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INVESTIGATIVE REPORT
Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin
Lydia Brandl, Daniela Hartmann, Thomas Kirchner, Antje Menssen
Deregulated Hedgehog signalling is a driver of basal cell carcinomas. One effector of the Hedgehog pathway is n-MYC. c/n-MYC proteins, NAMPT and DBC1 are linked to SIRT1 in a positive feedback loop that may contribute to tumorigenesis of basal cell carcinoma. In 5 basal cell carcinoma types immunohistochemistry revealed n-MYC, NAMPT and SIRT1 expression. DBC1 was homogenously expressed in all epit ...
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SHORT COMMUNICATION
A Case of Ankyloblepharon-ectodermal Defects-cleft Lip/palate-syndrome with Choanal Atresia and Skin Erosions: Phenotypic Variability of TP63-related Disorders
Luana Niculescu, Matias Wagner, Dominik S. Westphal, Marcus Fischer, Walter Mihatsch, Anke Prothmann, Thomas Ruzicka, Andreas Wollenberg, Hans Wolff, Heinrich Schmidt, Kathrin A. Giehl
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
A Myxoid Fibrotic Reaction Pattern is Associated with Metastatic Risk in Cutaneous Squamous Cell Carcinoma
Eugenia Hernández-Ruiz, Inmaculada Hernández-Muñoz, Emili Masferrer, Carla Ferrándiz-Pulido, Evelyn Andrades, Javier Gimeno, Xavier Duran, Vicente García-Patos, Ramon M. Pujol, Agusti Toll
Although desmoplasia has been associated with poor prognoses in cutaneous squamous cell carcinoma, little attention has been paid to the patterns of fibrosis. This study aimed to examine the different stromal fibrotic patterns as markers of metastatic risk. We performed a multicenter retrospective study that included 102 cutaneous squamous cell carcinomas (52 non-metastatic and 50 metastatic carci ...
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SHORT COMMUNICATION
Acquired Partial Lipodystrophy Associated with Anti-Mi-2 Antibody-positive Adult-onset Dermatomyositis
Ken Shiraishi, Mikiko Tohyama, Koji Sayama
Abstract is missing (Short communication)
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REVIEW
Role of the Gut Microbiota in Atopic Dermatitis: A Systematic Review
Elisabeth B.M. Petersen, Lone Skov, Jacob P. Thyssen, Peter Jensen
The immune mechanisms involved in atopic dermatitis (AD) are complex and little is known about the possible role of the gut microbiota in the aetiopathogenesis of AD. A systematic review of the literature was performed according to PRISMA guidelines, and included 44 of 2,199 studies (26 observational and 18 interventional studies). Detection of gut microbiota was performed by either 16s rRNA PCR, ...
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CLINICAL REPORT
Prevalence of Psoriasis and Psoriatic Arthritis and Patient Perceptions of Severity in Sweden, Norway and Denmark: Results from the Nordic Patient Survey of Psoriasis and Psoriatic Arthritis
Kjersti Danielsen, Albert Duvetorp, Lars Iversen, Mikkel Østergaard, Oliver Seifert, Kåre Steinar Tveit, Lone Skov
Optimal clinical management of psoriasis and psoriatic arthritis (PsA) Optimal clinical management of psoriasis and psoriatic arthritis (PsA) requires understanding of the impact on patients. The NORdic PAtient survey of Psoriasis and PsA (NORPAPP) aimed to obtain current data on disease prevalence and patient perceptions in Sweden, Denmark and Norway. Among 22,050 individuals questioned, the repo ...
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SPECIAL REPORT
Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis
Solam Lee, Young Bin Lee, Sung Jay Choe, Won-Soo Lee
Treatment of male androgenetic alopecia with 5α-reductase inhibitors is efficacious. However, the risk of adverse sexual effects remains controversial. This systematic review and meta-analysis investigated the risk of adverse sexual effects due to treatment of androgenetic alopecia in male patients with finasteride, 1 mg/day, or dutasteride, 0.5 mg/day. Fifteen randomized double-blinded placebo-c ...
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CLINICAL REPORT
Diagnostic Accuracy of Non-melanocytic Pink Flat Skin Lesions on the Legs: Dermoscopic and Reflectance Confocal Microscopy Evaluation
Ignacio Gómez-Martín, Sara Moreno, Xavier Duran, Ramon M. Pujol, Sonia Segura
Pink flat skin lesions on the legs in elderly people represent a diagnostic challenge due to the paucity of clinical and dermoscopic evidence. A prospective study of 114 pink flat lesions on the legs of 85 elderly patients was performed to describe the utility of reflectance confocal microscopy in this clinical context. Evaluation of clinical, dermoscopic and confocal parameters and calculation of ...
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INVESTIGATIVE REPORT
Identification of a Single Nucleotide Polymorphism in NFKBIA with Different Effects on Psoriatic Arthritis and Cutaneous Psoriasis in China
Qing Zhao, Yonghu Sun, Xi’an Fu, Zhenzhen Wang, Gongqi Yu, Zhenhua Yue, Yaru Wang, Huimin Zhang, Chuan Wang, Hong Liu, Qing Yang, Furen Zhang
Genome-wide association studies have recently identified a number of non-major histocompatibility complex regions associated with psoriatic arthritis. However, data on Chinese patients with psoriatic arthritis and the differences between psoriatic arthritis and cutaneous psoriasis are limited. This study genotyped 12 single nucleotide polymorphisms in 379 patients with psoriatic arthritis, 376 wit ...
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SHORT COMMUNICATION
Unresectable Non-metastatic Primary Melanoma: Complete Remission Following Treatment with Anti-Programmed-cell-death-receptor 1
Coralie Lheure, Caroline Hoffmann, Nora Kramkimel, Julie Plée, Nathalie Franck, Clélia Vanhaecke, Gabrielle Goldman-Lévy, Guillaume Bataillon, Diane Damotte, Nicolas Dupin, Selim Aractingi, Florent Grange, Sarah Guégan
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Langerhans Cell Histiocytosis with Lymph Node Involvment Presenting as Erythroderma
Huiqin Zhu, Yannan Ma, Ling Sun, Rongxin Zhang, Li Lv, Aoxue Wang
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Two Novel Mutations in the ERCC8 Gene in a Patient with Ultraviolet-sensitive Syndrome
Yue Li, Luyao Zheng, Fuying Chen, Zhirong Yao, Ming Li
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Granular IgA Deposits in the Skin of Patients with Coeliac Disease: Is it Always Dermatitis Herpetiformis?
Veronica Bonciolini, Emiliano Antiga, Beatrice Bianchi, Elena Del Bianco, Alessandra Ninci, Vincenza Maio, Nicola Pimpinelli, Marzia Caproni
Coeliac disease is an immune-mediated enteropathy driven by gluten, which can be associated with dermatitis herpetiformis. The presence of granular IgA deposits, detected by direct immunofluorescence, is the hallmark of dermatitis herpetiformis; nevertheless, IgA deposits have also been demonstrated in healthy skin of patients with coeliac disease. The main objective of this study was to investiga ...
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SHORT COMMUNICATION
A Postzygotic ATP2A2 Novel Mutation Identified by Next-generation Sequencing in Mosaic Darier Disease
Liliana Guerra, Cristina Pedicelli, Vittoria Proto, Angelo Giuseppe Condorelli, Cinzia Mazzanti, Daniele Castiglia
Abstract is missing (Short Communication)
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QUIZ
Disseminated Erythematous Papules and Pustules: A Quiz
Yasuyuki Fujita, Chihiro Shiiya, Yuka Inamura-Takashima, Toshifumi Nomura, Akihiko Shibaki, Hiroshi Shimizu
Abstract is missing (Quiz)
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BOOK REVIEW
Cutaneous Malignancies. A surgical perspective
Lisa Naysmith
Abstract is missing (Book review)
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BOOK REVIEW
Therapy for Severe Psoriasis, 1st Edition
Lone Skov
Abstract is missing (Book review)
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IN THIS ISSUE
Comment on: Quimp: A word meaning “quality of life impairment”
Pavel V. Chernyshov
Abstract is missing (In this Issue...)
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IN THIS ISSUE
Have you measured the patient’s quimp?
Magnus Lindberg
Abstract is missing (In this Issue...)
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BOOK REVIEW
Neonatal and Infant Dermatology, 3rd edition
Regina Fölster-Holst
Abstract is missing (Book review)
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