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Preview of fully accepted papers, still not published in any volume

QUIZ
Rapidly Growing Nodule on the Finger of a 20-year-old Woman: A Quiz
Alexander Zink, Alicia Pichlmeier, Tatjana Fischer, Tilo Biedermann
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Sarcoidal Foreign Body Reaction as a Severe Side-effect to Permanent Makeup: Successful Treatment with Intralesional Triamcinolone
Jörg Tittelbach, Melanie Peckruhn, Sibylle Schliemann, Peter Elsner
Abstract is missing (Short communication)
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QUIZ
An Erythematous Papular Rash on the Left Flank of a 31-year-old Woman: A Quiz
Emily Rudd, Nicholas Francis, Luke Moore, Louise Fearfield
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Abatacept Improves Skin-score and Reduces Lesions in Patients with Localized Scleroderma: A Case Series
Simon Wehner Fage, Kristian Bakke Arvesen, Anne Braae Olesen
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Generalized Purpura as an Atypical Skin Manifestation of Adult-onset Still’s Disease in a Patient with Behçet’s Disease
Chika Omigawa, Takashi Hashimoto, Takaaki Hanafusa, Takeshi Namiki, Ken Igawa, Hiroo Yokozeki
Abstract is missing (Short communication)
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CLINICAL REPORT
Systemic Inflammation and Evidence of a Cardio-splenic Axis in Patients with Psoriasis
Kasper F. Hjuler, Lars C. Gormsen, Mikkel H. Vendelbo, Alexander Egeberg, Jakob Nielsen, Lars Iversen
The spleen is thought to play a role in atherosclerosis-associated immunity and cardiovascular research has indicated the existence of a cardio-splenic axis. The aim of this study was to assess splenic 18F-fluorodeoxyglucose uptake as a measure of systemic inflammation in patients with untreated psoriasis compared with historical controls assessed by positron emission tomography-computed tomograph ...
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CLINICAL REPORT
Epidemiology and Medication Trends in Patients with Psoriasis: A Nationwide Population-based Cohort Study from Korea
Ju Hee Han, Ji Hyun Lee, Kyung Do Han, Hyun-Min Seo, Chul Hwan Bang, Young Min Park, Jun Young Lee, Yong Gyu Park
This study investigated the prevalence of psoriasis and trends in prescription of medications for patients with psoriasis using the Korean National Health Insurance Claims Database from 2006 to 2015. The prevalence of psoriasis and psoriatic arthritis per 10,000 people increased from 47.4 to 61.5 and from 0.04 to 0.23 respectively. The prescription of topical agents was a mean of 73.3%. For system ...
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SHORT COMMUNICATION
Laser-assisted Photodynamic Therapy or Laser-assisted Amorolfine Lacquer Delivery for Treatment of Toenail Onychomycosis: An Open-label Comparative Study
Amir Koren, Fares Salameh, Eli Sprecher, Ofir Artzi
Abstract is missing (Short communication)
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CLINICAL REPORT
Blood Predictive Biomarkers for Nivolumab in Advanced Melanoma
Edouard Chasseuil, Mélanie Saint-Jean, Hannah Chasseuil, Lucie Peuvrel, Gaëlle Quéreux, Jean-Michel Nguyen, Aurélie Gaultier, Emilie Varey, Amir Khammari, Brigitte Dréno
Nivolumab response rate is 40% in metastatic melanoma. Few studies have evaluated pre-treatment biomarkers predictive of response. The aim of this study was to identify potential peripheral blood biomarkers associated with survival in patients with advanced melanoma treated with nivolumab. All advanced melanoma cases treated with anti-programmed cell death protein 1 (anti-PD1) over a 3-year period ...
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SHORT COMMUNICATION
Eyelid Dermatitis as a Side Effect of Interleukin-17A Inhibitors in Psoriasis
Yuichi Teraki, Aya Takahashi, Yumiko Inoue, Saori Takamura
Abstract is missing (Short communication)
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CLINICAL REPORT
Epidermolysis Bullosa (EB) Acquisita in an Adult Patient with Previously Unrecognized Mild Dystrophic EB and Biallelic COL7A1 Mutations
Liliana Guerra, Angelo Giuseppe Condorelli, Paola Fortugno, Valentina Calabresi, Cristina Pedicelli, Giovanni Di Zenzo, Daniele Castiglia
Circulating anti-type VII collagen autoantibodies are frequently detected in patients with recessive dystrophic epidermolysis bullosa (RDEB). However, evidence supporting their pathogenic role in inducing epidermolysis bullosa acquisita (EBA) has been provided for only one individual with dominant dystrophic epidermolysis bullosa (DDEB). We describe here a patient who presented with dystrophic toe ...
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SHORT COMMUNICATION
Methotrexate Management in Psoriasis: Are We Following the Guidelines?
Tora Lindqvist, Louai A. Salah, Martin Gillstedt, Ann-Marie Wennberg, Amra Osmancevic
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Significant Changes in the Skin Microbiome in Patients with Chronic Plaque Psoriasis after Treatment with Narrowband Ultraviolet B
Malin Assarsson, Albert Duvetorp, Olaf Dienus, Jan Söderman, Oliver Seifert
Changes in the skin microbiome have been shown to promote cutaneous inflammation. The skin microbiome of patients with chronic plaque type psoriasis was analysed before and after treatment with narrowband ultraviolet B (UVB). Swab samples of the microbiome were taken from lesional and non-lesional skin of 26 patients. Microbiotas were characterized by sequencing 16S rRNA bacterial genes on the Ill ...
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INVESTIGATIVE REPORT
The Position of Targeted Next-generation Sequencing in Epidermolysis Bullosa Diagnosis
Cristina Has, Julia Küsel, Antonia Reimer, Julia Hoffmann, Franziska Schauer, Andreas Zimmer, Judith Fischer
The precise classification of epidermolysis bullosa (EB) into 4 main types and more than 30 subtypes is based on the level of skin cleavage, as well as clinical and molecular features, and is crucial for early prognostication, case management, genetic counselling and prenatal or pre-implantation diagnosis. We report here the molecular pathology of 40 consecutive cases of suspected EB, which were i ...
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SHORT COMMUNICATION
Indeterminate Cell Histiocytosis Presenting with Leonine Facies
Cheng Chen, Giang Huong Nguyen, Yue-Ping Zeng
Abstract s missing (Short communication)
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SHORT COMMUNICATION
Ramucirumab-induced Multiple Haemangiomas of the Skin: Two Case Reports
Hideyuki Kosumi, Wataru Nishie, Tatsuro Sugai, Ellen Toyonaga, Norihiro Yoshimoto, Hiroyuki Nakamura, Ryota Horibe, Yasuo Kitamura, Hiroshi Nakatsumi, Hiroshi Shimizu
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Delusional Infestation: Perspectives from Scottish Dermatologists and a 10-year Case Series from a Single Centre
Yee Ling Wong, Andrew Affleck, Alexander M. Stewart
Perceptions of the clinical management of delusional infestation (DI) were compared with clinical outcomes in this 10-year case series from a single centre in Dundee, UK. An online questionnaire (survey-monkey, a TM brand of online survey available for free for basic use) was sent to Scottish Dermatologists to gauge their opinions and confidence in the management of DI. Also, a retrospective revie ...
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CLINICAL REPORT
Clinical, Viral and Genetic Characteristics of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Shanghai, China
Xiaojin Wu, Fanping Yang, Shengan Chen, Hao Xiong, Qinyuan Zhu, Xudong Gao, Qinghe Xing, Xiaoqun Luo
DRESS is one of the most severe drug reactions. The aim of this retrospective study was to summarize the clinical presentation, genetic predisposition and prognostic factors of DRESS. A total of 52 patients with DRESS, who were inpatients at a medical referral centre in Shanghai, China, from January 2011 to December 2016, were analysed retrospectively. All the patients had skin eruption, 83% had l ...
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SHORT COMMUNICATION
Nodular Melanoma: A Histopathologic Entity?
Adèle C. Green, Amaya Viros, Maria Celia B. Hughes, Caroline Gaudy-Marqueste, Victoria Akhras, Martin G. Cook, Richard Marais
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
The Pain Quality Assessment Scale for epidermolysis bullosa
Nicholas H.B. Schräder, Wing Y. Yuen, Marcel F. Jonkman
Pain is one of the most debilitating symptoms in epidermolysis bullosa (EB) leading to reduced quality of life. Pain in EB comprises both neuropathic and non-neuropathic qualities. An assessment of pain qualities has not formerly been completed in EB. The Pain Quality Assessment Scale (PQAS) is an adjusted version of the validated Neuropathic Pain Scale and includes 20 pain qualities and descripto ...
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INVESTIGATIVE REPORT
Validation of the Itch Severity Item as a Measurement Tool for Pruritus in Patients with Psoriasis: Results from a Phase 3 Tofacitinib Program
Sonja Ständer, Thomas Luger, Joseph C. Cappelleri, Andrew G. Bushmakin, Carla Mamolo, Michael A. Zielinski, Anna M Tallman, Gil Yosipovitch
Tofacitinib is an oral Janus kinase inhibitor. This post-hoc analysis aimed to investigate the psychometric properties of the Itch Severity Item (ISI), a numeric rating scale from 0 (no itching) to 10 (worst possible itching) for pruritus in psoriasis, and review the effect of tofacitinib on pruritus in patients with psoriasis participating in Phase 3 studies (N = 3,641). The ISI showed high t ...
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CLINICAL REPORT
Effects of a Hybrid Education Programme for Korean Mothers of Children with Atopic Dermatitis
Je-Bog Yoo, Jennie C. De Gagne, Seung-Hyeon S. Jeong, Chan-Woo Jeong
Atopic dermatitis (AD), a common childhood skin disorder, can limit a child’s learning and physical activities. South Korean mothers, as primary caregivers, experience anxiety and helplessness when caring for their ill children. The aim of this study was to develop a hybrid AD education programme (consisting of a face-to-face session followed by 8 online sessions) and evaluate its effects on anx ...
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SHORT COMMUNICATION
Incidence of Actinic Keratosis and Risk of Skin Cancer in Subjects with Actinic Keratosis: A Population-based Cohort Study
Ji Hyun Lee, Yeong Ho Kim, Kyung Do Han, Young Min Park, Jun Young Lee, Yong Gyu Park, Young Bok Lee
Abstract is missing (Short communication)
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QUIZ
A Rapidly Expanding Ulcer in the Armpit of a 48-year-old Man: A Quiz
Yael Renert-Yuval, Sharon Merims, Alexander Maly, Yuval Ramot
Abstract is missing (Quiz)
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SPECIAL REPORT
Treatment of Scleroedema Adultorum Buschke: A Systematic Review
Diana Miguel, Sibylle Schliemann, Peter Elsner
Scleroedema adultorum Buschke is a rare skin disease, which can be divided into 3 subtypes: classic type, occurring after respiratory infections; a type lacking association with infections; and a type associated with diabetes. Scleroedema adultorum Buschke is characterized by thickening and tightening of the skin, which typically starts at the neck. In half of patients, spontaneous remission may o ...
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SPECIAL REPORT
Treatment of Cutaneous Pseudolymphoma: A Systematic Review
Diana Miguel, Melanie Peckruhn, Peter Elsner
Cutaneous pseudolymphoma (CPL) is a reactive polyclonal T- or B-cell lymphoproliferative process. CPL may appear as localized or disseminated skin lesions. While most cases of CPL are idiopathic, they may also occur as a response to, for example, contact dermatitis, arthropod reactions, and bacterial infections. CPL can be classified based on its clinical features, but all variants have similar hi ...
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REVIEW
Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders
Xue-Gang Xu, Hong-Duo Chen
Prostanoids, including prostaglandins (PGs) and thromboxane A2 (TXA2), are a family of lipid-derived autacoids that modulate many physiological systems and pathological contexts. Prostanoids are generated by sequential metabolism of arachidonic acid, catalysed by cyclo-oxygenase, to PGH2, which is then converted to PGD2, PGE2, PGF2α, PGI2 and TXA2, catalysed by their specific synthases. Recent ev ...
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SHORT COMMUNICATION
Generalized Bullous Fixed Drug Eruption Following Metamizole (Re-)Exposure: A Medical Error-analytic Case Study
Peter Elsner, Maja Mockenhaupt
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Ex vivo Culture of Duodenal Biopsies from Patients with Dermatitis Herpetiformis Indicates that Transglutaminase 3 Antibody Production Occurs in the Gut
Minna Hietikko, Kaisa Hervonen, Tuire Ilus, Teea Salmi, Heini Huhtala, Kaija Laurila, Tiina Rauhavirta, Timo Reunala, Katri Kaukinen, Katri Lindfors
Coeliac disease and dermatitis herpetiformis (DH) are characterized by autoantibodies targeting transglutaminase (TG)2 and TG3, respectively. Previous studies show that TG2 antibodies are produced in the gut and can be assessed in organ culture of small-intestinal biopsies from patients with coeliac disease. Thus far, no studies have investigated TG3 antibodies in organ culture of biopsies from pa ...
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INVESTIGATIVE REPORT
Atypical Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 in Denmark: A Diagnostic Mimicker
Hans-Henrik Horsten, Michael Kemp, Thea K. Fischer, Kim H. Lindahl, Anette Bygum
Since 2008, outbreaks of atypical hand, foot, and mouth disease (HFMD) in children and adults have been reported worldwide. The majority of these outbreaks are caused by a new lineage of Coxsackie virus A6 (CV-A6) presenting a more severe clinical phenotype than the classical childhood HFMD caused by CV-A16. Between June 2014 and January 2016, 23 cases of atypical HFMD disease presented at a Derma ...
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CLINICAL REPORT
Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis
Louise Lönndahl, Mikael Holst, Maria Bradley, Hassan Killasli, Johan Heilborn, Martin A. Hall, Elvar Theodorsson, Jadwiga Holmberg, Klas Nordlind
Atopic dermatitis (AD) is a chronic, itchy, inflammatory skin disorder that may worsen due to stress and anxiety. Tachykinins have been suggested to be involved in the inflammation in AD, as well as pruritus. Aprepitant is a NK-1 receptor antagonist. This open randomized trial evaluated the effect of aprepitant added to topical treatment in adult patients with moderate–severe AD. The treatment g ...
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SHORT COMMUNICATION
Post-traumatic Stress Disorder in Patients and Relatives Following a Diagnosis of de novo Neurofibromatosis Type 1
Johanna Huguen, Séverine Audebert-Bellanger, Emilie Brenaut, Laurent Misery, Claire Abasq-Thomas
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study
Jeanette Halskou Hesselvig, Kristian Kofoed, Jashin J. Wu, Lene Dreyer, Gunnar Gislason, Ole Ahlehoff
Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort study of the entire Danish population aged ≥ 18 and ≤ 100 years was conducted, followed from 1997 to 2011 by individual-level linkage of natio ...
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QUIZ
Acquired Transverse Stripes on the Fingernails: A Quiz
Alya Alkhars, Marion Delaplace, Muriel Ouedraogo, Laurent Machet
Abstract is missing (Quiz)
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CLINICAL REPORT
Tailored Therapist-guided Internet-based Cognitive-behavioural Treatment for Psoriasis and Rheumatoid Arthritis: Two Case Reports
Saskia Spillekom-van Koulil, Maaike Ferwerda, Sylvia van Beugen, Henriët van Middendorp, Peter C.M. van de Kerkhof, Piet L.C.M. van Riel, Andrea W.M. Evers
Chronic somatic conditions, such as psoriasis, arthritis psoriatica and rheumatoid arthritis, have a large impact on patients’ lives. Tailored therapist-guided internet-based cognitive-behavioural therapy (ICBT) has been shown to be effective in improving physical and psychological well-being in these patients. Two cases are presented here, in order to provide an in-depth illustration of the cou ...
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CLINICAL REPORT
Development and Validation of the Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) Questionnaire
Rick Waalboer-Spuij, Loes M. Hollestein, Reinier Timman, Lonneke V. van de Poll-Franse, Tamar E. Nijsten
Health-related quality of life (HRQoL) is important in the management of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Disease-specific questionnaires exist, but with important shortcomings. The aim of this study was to develop and validate a questionnaire suitable for use in all patients with BCC and those with SCC. In a 4-phase trajectory, a preliminary questionnaire was created ...
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CLINICAL REPORT
Granuloma Annulare and Morphea: Correlation with Borrelia burgdorferi Infections and Chlamydia-related Bacteria
Lauri Tolkki, Kati Hokynar, Seppo Meri, Jaana Panelius, Mirja Puolakkainen, Annamari Ranki
A retrospective study of 109 skin biopsies with granuloma annulare (GA) or morphea histology from patients with suspected tick bite was performed. Biopsies were tested for cutaneous Borrelia burgdorferi DNA using PCR. The same biopsies were analysed for tick-borne novel agents, Chlamydia-related bacteria (members of the Chlamydiales order), using a PCR-based method. Borrelia DNA was detected in 7/ ...
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SHORT COMMUNICATION
Infectious Cellulitis Caused by Streptococcus halichoeri
Pascal Del Giudice, Céline Plainvert, Thomas Hubiche, Asmaa Tazi, Agnès Fribourg, Claire Poyart
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema
Floor M. Garritsen, Jorien van der Schaft, Marlies de Graaf, Dirk Jan Hijnen, Carla A.F. Bruijnzeel-Koomen, Marcel P.H. van den Broek, Marjolein S. De Bruin-Weller
Abstract is missing (Short communication)
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SHORT COMMUNICATION
The Regibul Register: A Tool for Monitoring the Distribution and Incidence of Autoimmune Bullous Dermatoses in Three French Regions, 2010 to 2015
Jeffrey Loget, Coralie Barbe, Sophie Duvert-Lehembre, Christophe Bédane, Michaël Maizières, Pascal Joly, Amélie Couraud, Julie Plée, Philippe Bernard
Abstract is missing (Short communication)
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CLINICAL REPORT
Correlation Between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis Treated with Ustekinumab
Jeanette Halskou Hesselvig, Alexander Egeberg, Nikolai Dyrberg Loft, Claus Zachariae, Kristian Kofoed, Lone Skov
Monitoring of biological treatment efficacy for psoriasis is based on clinical evaluation and patient’s quality of life. However, long-term correlation between Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) in real life has not been studied in patients treated with ustekinumab. All patients with psoriasis treated with ustekinumab at our department were include ...
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COMMENTARY
Matrix-Assisted Laser Desorption/Ionisation Time-Of-Flight (MALDI-TOF) Mass Spectrometry in Dermatology
David Chandler, Roderick J. Hay
Abstract is missing (Commentary)
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INVESTIGATIVE REPORT
Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back
Marie-Ange Dagnelie, Stéphane Corvec, Mélanie Saint-Jean, Valérie Bourdès, Jean-Michel Nguyen, Amir Khammari, Brigitte Dréno
Propionibacterium acnes, a major member of normal skin microbiota, is subdivided into 6 phylotypes: IA1, IA2, IB, IC, II and III. This study investigated P. acnes subgroups on the face and back in patients with severe acne and in healthy controls. In 71.4% of patients with severe acne, P. acnes phylotypes were identical on the face and back, whereas this was the case in only 45.5% of healthy contr ...
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QUIZ
An Asymptomatic Plaque on the Chest: A Quiz
Alessandro Pileri, Susanna Gunnella, Vieri Grandi, Vincenza Maio, Nicola Pimpinelli
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Biological and Clinical Response to Omalizumab in a Patient with Bullous Pemphigoid
Sébastien Menzinger, Gürkan Kaya, Enno Schmidt, Lionel Fontao, Emmanuel Laffitte
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Risk Factors for Surgical Site Infections in Dermatological Surgery
Xiaomeng Liu, Melissa Sprengers, Patty J. Nelemans, Klara Mosterd, Nicole W.J. Kelleners-Smeets
Current literature on risk factors for surgical site infection (SSI) in dermatological surgery in the absence of antibiotic prophylaxis is limited. The aim of this study was to retrospectively evaluate patients presenting for dermatological surgery. A total of 1,977 procedures were reviewed. SSI was clinically suspected in 79 (4.0%) patients and confirmed by culture in 38 (1.9%). Using the stricte ...
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CLINICAL REPORT
Estimation of Direct Melanoma-related Costs by Disease Stage and by Phase of Diagnosis and Treatment According to Clinical Guidelines
Alessandra Buja, Gino Sartor, Manuela Scioni, Antonella Vecchiato, Mario Bolzan, Vincenzo Rebba, Vanna Chiarion Sileni, Angelo Claudio Palozzo, Maria Montesco, Paolo Del Fiore, Vincenzo Baldo, Carlo Riccardo Rossi
Cutaneous melanoma is a major concern in terms of healthcare systems and economics. The aim of this study was to estimate the direct costs of melanoma by disease stage, phase of diagnosis, and treatment according to the pre-set clinical guidelines drafted by the AIOM (Italian Medical Oncological Association). Based on the AIOM guidelines for malignant cutaneous melanoma, a highly detailed decision ...
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SHORT COMMUNICATION
Allergic Contact Dermatitis Due to Ripasudil Hydrochloride Hydrate in Eye-drops: A Case Report
Minori Kusakabe, Yasutomo Imai, Masaru Natsuaki, Kiyofumi Yamanishi
Abstract is missing (Short communication)
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INVESTIGATIVE REPORT
Search for RASA1 Variants in Capillary Malformations of the Legs in 113 Children: Results From the French National Paediatric Cohort CONAPE
Annabel Maruani, Marine Durieux-Verde, Juliette Mazereeuw-Hautier, Olivia Boccara, Ludovic Martin, Christine Chiaverini, Catherine Eschard, Nathalie Bénéton, Pierre Vabres, Xavier Balguerie, Patrice Plantin, Didier Bessis, Sébastien Barbarot, Ali Dadban, Catherine Droitcourt, Aline Berthelot, Gérard Lorette, Sophie Leducq, Mahtab Samimi, Christian Andres, Agnès Caille, Patrick Vourc'h; and Groupe de Recherche de la Société Française de Dermatologie
Patients with an inherited autosomal-dominant disorder, capillary malformation–arteriovenous malformation (CM-AVM), frequently have mutations in Ras P21 protein activator 1 (RASA1). The aims of this study were to determine the prevalence of germline RASA1 variants in a French multicentre national cohort of children, age range 2–12 years, with sporadic occurrence of capillary malformation (CM) ...
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CLINICAL REPORT
Patients’ and Physicians’ Preferences for Systemic Psoriasis Treatments: A Nationwide Comparative Discrete Choice Experiment (PsoCompare)
Marthe-Lisa Schaarschmidt, Raphael Herr, Mandy Gutknecht, Katharina Wroblewska, Sascha Gerdes, Michael Sticherling, Matthias Augustin, Wiebke K. Peitsch
Systemic antipsoriatic treatment options are increasing rapidly. The aim of this nationwide discrete choice experiment was to compare patients’ (n = 222) and physicians’ (n = 78) preferences for outcome and process attributes of systemic antipsoriatics using Relative Importance Scores (RIS). Both groups considered Psoriasis Area and Severity Index 90 (PASI 90) to be most important (RIS ...
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REVIEW
Fractional Carbon Dioxide Laser as an "Add-on" Treatment for Vitiligo: A Meta-analysis with Systematic Review
Hyun Jung Kim, Eun Sun Hong, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
Treatment of vitiligo is challenging and requires a multidisciplinary approach. Fractional carbon dioxide (CO2) laser as an add-on to conventional treatment has been reported to be effective, but there is no consensus on its use. A systematic review was performed by searching major databases for relevant publications to February 2017. Six studies with 85 participants were included. For those with ...
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REVIEW
Chronic Prurigo of Nodular Type: A Review
Claudia Zeidler, Athanasios Tsianakas, Manuel Pereira, Hartmut Ständer, Gil Yosipovitch, Sonja Ständer
Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules. PN evolves along with chronic pruritus in the context of diverse dermatological, systemic, neurological or psychiatric conditions. Permanent scratching is possibly a major trigger of PN, although its exact pathophysiology remain ...
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CLINICAL REPORT
Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area
Eriika Mansikka, Teea Salmi, Katri Kaukinen, Pekka Collin, Heini Huhtala, Timo Reunala, Kaisa Hervonen
Dermatitis herpetiformis (DH) is an extra-intestinal manifestation of coeliac disease. The highest currently reported prevalence of DH is in Finland, but knowledge of diagnostic delay is limited. This study investigated the duration of rash prior to diagnosis in 446 patients with DH, analysing the results in 3 periods of 15 years. The diagnosis was considered delayed when the duration of rash befo ...
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QUIZ
Chronic Nodular Dermatosis: A Quiz
Marco Cusini, Stefano Ramoni, Vinicio Boneschi, Sebastiano Recalcati
Abstract is missing (Quiz)
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SHORT COMMUNICATION
Late-onset Erythropoietic Protoporphyria Associated with Myelodysplastic Syndrome Treated with Azacitidine
Ai Yoshioka, Susumu Fujiwara, Hiroki Kawano, Hajime Nakano, Shigeru Nakano, Toshimitsu Matsui, Yoshio Katayama, Chikako Nishigori
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Heterogeneity of Skin Re-innervation After Burns and Factors Involved in its Regulation: A Pilot Study
Virginie Buhé, Alexandra Trimaille, Martine Schollhammer, Florence Morvan, Weiguo Hu, Christophe Egles, Alexis Desmoulière, Laurent Misery
Abstract is missing (Short communication)
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SHORT COMMUNICATION
Modified Measles: A Diagnostic Challenge
Jozefien Roose, Celine Rohaert, Annelien Jadoul, Regina Fölster-Holst, Dirk van Gysel
Abstract is missing (Short communication)
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CLINICAL REPORT
Patients' Illness Perception as a Tool to Improve Individual Disease Management in Primary Cutaneous Lymphomas
Stefanie Porkert, Eva Lehner-Baumgartner, Julia Valencak, Robert Knobler, Elisabeth Riedl, Constanze Jonak
The Revised Illness Perception Questionnaire (IPQ-R) has been shown to assess illness perception reproducibly in primary cutaneous T-cell lymphomas (CTCL). Illness perception reflects patients' individual concepts of understanding and interpretation of the disease, influencing illness behaviour and health-related quality of life (HRQOL). This study investigated the clinical relevance of the relati ...
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INVESTIGATIVE REPORT
Placebo Effects of Open-label Verbal Suggestions on Itch
Stefanie H. Meeuwis, Henriët van Middendorp, Dieuwke S. Veldhuijzen, Antoinette I.M. van Laarhoven, Jan De Houwer, Adriana P.M. Lavrijsen, Andrea W.M. Evers
Placebo effects are positive outcomes that are not due to active treatment components, which may be elicited even when patients are aware of receiving an inert substance (open-label). This proof-of-principle study investigated for the first time whether open-label placebo effects on itch can be induced by verbal suggestions alone. Ninety-two healthy volunteers were randomized to experimental (open ...
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CLINICAL REPORT
Cutaneous Chronic Graft Versus Host Disease Following Allogeneic Haematopoietic Stem Cell Transplantation in Children: A Retrospective Study
Rony Shreberk-Hassidim, Michal Neumark, Shoshana Greenberger, Gal Goldstein, Ayal Hassidim, Yuval Dukler, Alexander Maly, Polina Stepensky, Vered Molho-Pessach
Chronic graft versus host disease (cGVHD) is a complication of allogeneic haematopoietic stem cell transplantation (HSCT). The aim of this study was to clinically characterize childhood cutaneous cGVHD. A retrospective study of children treated with HSCT at 2 tertiary medical centres in Israel between 2011 and 2014 was performed. A total of 112 children were included. Cutaneous cGVHD developed in ...
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CLINICAL REPORT
Burden of Aquagenic Pruritus in Polycythaemia Vera
Edyta Lelonek, Łukasz Matusiak, Tomasz Wróbel, Jacek Kwiatkowski, Jacek C. Szepietowski
Aquagenic pruritus (AP) has a significant influence on quality of life (QoL) in patients with polycythaemia vera. This study analysed the impact of AP on patient well-being in 102 patients with polycythaemia vera. Intensity of pruritus was evaluated using a visual analogue scale (VAS), verbal rating scale (VRS) and a 4-item Itch Questionnaire. Psychosocial aspects of AP were assessed with the Hosp ...
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SHORT COMMUNICATION
Central Obesity in Children with Psoriasis
Lucia Guidolin, Marco Borin, Elena Fontana, Francesca Caroppo, Stefano Piaserico, Anna Belloni Fortina
Abstract is missing (Short communication)
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CLINICAL REPORT
Nail Involvement in Alopecia Areata: A Questionnaire-based Survey on Clinical Signs, Impact on Quality of Life and Review of the Literature
Yvonne B.M. Roest, Henriët van Middendorp, Andrea W.M. Evers, Peter C.M. van de Kerkhof, Marcel C. Pasch
Alopecia areata (AA) is an immune-mediated disease causing temporary or permanent hair loss. Up to 46% of patients with AA also have nail involvement. The aim of this study was to determine the presence, types, and clinical implications of nail changes in patients with AA. This questionnaire-based survey evaluated 256 patients with AA. General demographic variables, specific nail changes, nail-rel ...
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INVESTIGATIVE REPORT
Temporal Stability of the Healthy Human Skin Microbiome Following Dead Sea Climatotherapy
Michael Brandwein, Garold Fuks, Avigail Israel, Ashraf Al-Ashhab, Deborah Nejman, Ravid Straussman, Emmilia Hodak, Marco Harari, Doron Steinberg, Zvi Bentwich, Noam Shental, Shiri Meshner
Dead Sea climatotherapy (DSC) is a therapeutic modality for a variety of chronic skin conditions, yet there has been scarce research on the relationship between the cutaneous microbiota and disease states in response to DSC. We characterized the skin bacterial and fungal microbiome of healthy volunteers who underwent DSC. Bacterial community diversity remained similar before and after treatment, w ...
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QUIZ
Six-month History of a Split Thumbnail: A Quiz
Yosuke Mai, Hideyuki Ujiie, Takashi Anan, Hajime Miyazawa, Keisuke Imafuku, Kokichi Hamasaka, Hiroshi Shimizu
Abstract is missing (Quiz)
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SHORT COMMUNICATION
9q22.3 Microdeletion Syndrome with Multiple Basal Cell Carcinomas Treated with Vismodegib: Three Key Messages in One Patient
Alice Kieny, Valérie Kremer, Sophie Scheidecker, Dan Lipsker
Abstract is missing (Short communication)
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CLINICAL REPORT
Clinical Characteristics of Pruritus and Pain in Patients with Hidradenitis Suppurativa
Łukasz Matusiak, Justyna Szczęch, Karolina Kaaz, Edyta Lelonek, Jacek C. Szepietowski
A growing body of research has indicated that pruritus is an important feature of hidradenitis suppurativa (HS). This study evaluated pruritus and pain among 103 patients with HS. Pruritus and pain intensity were assessed with a visual analogue scale, numerical rating scale and 4-item Itch Questionnaire. Dermatology Life Quality Index (DLQI) was implemented to assess quality of life (QoL) issues. ...
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BOOK REVIEW
Therapy for Severe Psoriasis, 1st Edition
Lone Skov
Abstract is missing (Book review)
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IN THIS ISSUE
Comment on: Quimp: A word meaning “quality of life impairment”
Pavel V. Chernyshov
Abstract is missing (In this Issue...)
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IN THIS ISSUE
Have you measured the patient’s quimp?
Magnus Lindberg
Abstract is missing (In this Issue...)
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BOOK REVIEW
Neonatal and Infant Dermatology, 3rd edition
Regina Fölster-Holst
Abstract is missing (Book review)
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