Content » Vol 89, Issue 3

Clinical Report

Purely Cutaneous Langerhans' Cell Histiocytosis in an Adult Woman

Anna Campanati, Oriana Simonetti, Barbara Marconi, Katia Giuliodori, Giulia Ganzetti, Giuliano Brandozzi, Maria Luisa Bernardini, Renzo Ranaldi, Annamaria Offidani
DOI: 10.2340/00015555-0614


Langerhans’ cell histiocytosis (LCH) is a clonal, histiocytic, proliferative disorder of unknown aetiology originating from Langerhans’ cells. Although the clinical presentation and therapeutic approach to the disease in
children have been well established, few data are available concerning the disease in adults. Moreover, unique
cutaneous involvement by LCH in a woman older than 70 years has been described very rarely. We report here a case of a 75-year-old woman with cutaneous LCH confined to the inframammary fold, and highlight some medical problems regarding the management of a purely cutaneous form of LCH in adults.


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