Content » Vol 89, Issue 3

Clinical Report

Neopterin and C-Reactive Protein in the Course of Stevens-Johnson Syndrome: Report of a Case

Linda Bertram, Yvonne Liss and Michael Grözinger
DOI: 10.2340/00015555-0631

Abstract

We describe a patient originally suffering from a depressive syndrome who developed Stevens-Johnson syndrome after 12 days of treatment with lamotrigine. The clinical symptoms and the inflammation parameters neopterin and C-reactive protein were documented. Neopterin values showed a good correlation with the course of the disease, which, to the best of our knowledge, has not been reported previously. C-reactive protein followed the neopterin curve with a delay of 4 days. Since neopterin is a widely available parameter it should be considered as a routine measurement in this type of hyperergic reaction. It might help to identify the beginning, the maximum and the regression of the disease in order to support therapeutic decisions.

Significance

Supplementary content

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