Content » Vol 95, Issue 5

Clinical Report

Cyclosporine Treatment in Severe Gestational Pemphigoid

Laura Huilaja, Kaarin Mäkikallio, Katariina Hannula-Jouppi, Liisa Väkevä, Johanna Höök-Nikanne, Kaisa Tasanen
DOI: 10.2340/00015555-2032


Gestational pemphigoid, a rare autoimmune skin disease typically occurring during pregnancy, is caused by autoantibodies against collagen XVII. Clinically it is characterised by severe itching followed by erythematous and bullous lesions of the skin. Topical or oral glucocorticoids usually relieve symptoms, but in more severe cases systemic immunosuppressive treatments are needed. Data on immunosuppressive medication controlling gestational pemphigoid are sparse. We report 3 intractable cases of gestational pemphigoid treated with cyclosporine.


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