Content » Vol 62, Issue 5

Impairment of some microphage functions in recurrent herpes simplex

Simon M Jr, Djawari D.
DOI: 10.2340/0001555562434435

Abstract

Chemotactic, phagocytic and intracellular killing activities of polymorphonuclear leukocytes (PMNL) were investigated in vitro in 49 patients suffering from recurrent bouts of herpes simplex. A slight impairment of chemotactic activity and a markedly reduced capacity of killing Candida albicans blastospores were revealed. Phagocytic capacity and NADH-dependent oxidase activity of PMNL proved to be normal. The results point to an alteration of some PMNL functions in these patients.

Significance

Supplementary content

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