Kanerva L.
DOI: 10.2340/0001555568359361

Tubuloreticular structures (TRS) are intracellular tubular inclusions that can be detected by means of electron microscopy. TRS have earlier been found in autoimmune, viral and neoplastic diseases. Here the occurrence of TRS is for the first time described in allergic patch tests, where they were detected in dermal macrophages. TRS are believed to be reaction products of metabolically active cells, and the TRS described here are probably formed as a result of the activation of the immune system in allergic patch tests.