Content » Vol 71, Issue 2

On the putative mechanism of induction and regulation of melanogenesis by L-tyrosine.

Howe J, Costantino R, Slominski A
DOI: 10.2340/0001555571150152


The stimulation of melanogenesis by L-tyrosine in hamster melanoma is several-fold higher than that by norepinephrine, epinephrine, clonidine and isoproterenol and absent in the case of tyramine dopamine and phenylephrine. Therefore, the melanogenic effect of L-tyrosine in hamster melanoma follows a different pathway than that linked to the activation of dopaminergic and adrenergic receptors.


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