Content - Volume 71, Issue 2
Mechanical trauma to genital skin may favor the transmission of sexually transmitted diseases. To study differences between vulvar and forearm skin in epidermal repair after standardized trauma, transepidermal water loss, capacitance and pH of forearm and vulvar skin in 10 healthy premenopausal women were monitored for 7 days after a standardized trauma induced by tape stripping to glistening. Vul ...
A new, non-invasive chamber sampling technique for HPLC analysis of human epidermal urocanic acid isomers is described. Easily processed samples are obtained in a rapid and non-invasive manner, without discomfort to the patient. HPLC data from chamber samples are reproducible, and recorded urocanic acid isomer levels are comparable to those measured in samples taken with tape stripping technique.
The zinc absorption from zinc oxide applied on intact and on wounded skin were compared using two vehicles: one containing gum rosin and the other containing hydrocolloids. After treatment of intact human forearm skin for 48 h, the zinc concentration was more than two-fold higher in the epidermis and interstitial fluid beneath the rosin vehicle than beneath the hydrocolloid vehicle. Systemic absor ...