Content » Vol 77, Issue 1

Clinical Report

Metaplastic Bone Formation in the Subcutaneous Nodule of a Patient with Mixed Connective Tissue Disease

Bernhard JD.
DOI: 10.2340/0001555577064065

Abstract

Cutaneous ossification is a rare phenomenon in collagen diseases, despite the rather frequent occurrence in these diseases of dystrophic calcinosis. We observed metaplastic woven bone formation associated with calcification in biopsy material obtained from a 49-year-old woman suffering from mixed connective tissue disease together with multiple subcutaneous indurations. This is the first case of the presence of metaplastic bone formation in a patient with mixed connective tissue disease.

Significance

Supplementary content

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