Content - Volume 62, Issue 3

All articles

Desmosome formation in normal human epidermal cell culture
H Hino, T Kobayasi, G Asboe-Hansen
Keratinocytes were dissociated from normal human adult epidermis with clostridial collagenase, dithio-erythritol and trypsin, and cultured. Immediately after this, no connection was seen between contiguous cells. Ruptured desmosomes, with masses of tonofilaments and distinct attachment plaques were still left on the cell surface. As culture proceeded, however, they became internalized into cytopla ...
Pages: 185-191
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Phenotype of cells involved in mycosis fungoides and Sézary syndrome (blood and skin lesions): immunomorphological study with monoclonal antibodies
D Schmitt, P Souteyrand, J Brochier, J Czernielewski, J Thivolet
The phenotypic expression of immunocompetent cells involved in lesions of cutaneous T-cell lymphoma (mycosis fungoides and S?©zary syndrome) was studied by using monoclonal antibodies specific for T-cell subsets and HLA-DR antigens (OKT3, T4, T6, T8) (BL 6, BL 5, BL 2). In S?©zary syndrome, the phenotype of S?©zary cell is homogeneous (T3+, T4+, T8-, T6-, BL2-) and corresponds to the phenotype ...
Pages: 193-199
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An immunological study of patients with bullous pemphigoid
A. Hovmark, E. Asbrink
No abstract available.
Pages: 201-204
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Antiserum to intercellular material and basement membrane produced by immunization with oral epithelial cells
G. Singh, AE. Dolby
Antisera to non-enzymatically released oral epithelial cells were produced in rabbits. Reactivity with gingival sections, by immunofluorescence, was observed for intercellular (IC) and basement membrane (BM) zones. Both IC and BM reactivity could be blocked with Concanavalin A (500 and 1000 micrograms/ml respectively) and anti-human fibronectin serum. Pretreatment with pemphigus serum blocked IC r ...
Pages: 205-209
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Blood glutathione-peroxidase levels in skin diseases: effect of selenium and vitamin E treatment
L Juhlin, LE Edqvist, LG Ekman, K Ljunghall, M Olsson
Blood glutathione-peroxidase (GSH-Px) was determined in 61 healthy subjects and 506 patients with various skin disorders. Depressed levels were observed in patients with psoriasis, eczema, atopic dermatitis, vasculitis, mycosis fungoides and dermatitis herpetiformis. Low values of GSH-Px were also found in some patients with pemphigoid, acne conglobata, polymyositis, rheumatoid arthritis, sclerode ...
Pages: 211-214
Abstract  PDF
Histamine release from rat peritoneal mast cells exposed to ultraviolet light
B. Fjellner, Ö. Hägermark
After irradiation with ultraviolet light, rat peritoneal mast cells incubated with the histamine liberator compound 48/80 were found to have reduced capacity to release histamine. The action spectrum for histamine release inhibition seemed to be in the wavelength region of UVB. UV-light per se did not induce histamine liberation other than for dosages greater than or equal to 1.45 J/cm2. No such r ...
Pages: 215-220
Abstract  PDF
Methylglyoxal BIS (guanylhydrazone) and alpha-difluoromethylornithine-induced polyamine deprivation in psoriatic lesions
M Kousa, K Käpyaho, J Lauharanta, K Linnamaa, J Jänne, K Mustakallio
No abstract available.
Pages: 221-224
Abstract  PDF
Food iron absorption in patients with dermatitis herpetiformis
I Braide, W Kastrup, B Magnusson, H Mobacken, L Rossander
No abstract available.
Pages: 225-228
Abstract  PDF
Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution
F Brandrup, N Holm, N Grunnet, K Henningsen, HE Hansen
The variation in expression of psoriasis, in individuals with identical genetic constitutions, i.e. monozygotic twins, has been studied in a population-based sample of monozygotic twins in the Danish Twin Register. All verified and probable cases of psoriasis in twins, born between 1891 and 1930 inclusive, were ascertained. Results are presented of an examination of all members of index pairs in w ...
Pages: 229-236
Abstract  PDF
Polymorphous light eruption: a common reaction uncommonly recognized
WL Morison, RS. Stern
Polymorphous light eruption (PMLE) is usually considered to be an uncommon complaint, although the prevalence in the general population has not been studied. In a survey of 271 apparently healthy subjects, 10% gave a history consistent with a diagnosis of PMLE. The clinical characteristics in the survey cases of PMLE were similar in most respects to those of patients presenting to a clinic with th ...
Pages: 237-240
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Immunological markers of Langerhans´ cells in mycosis fungoides skin lesions
U. Tjernlund
The patterns of two immunological markers of epidermal Langerhans´ cells were compared in normal skin and mycosis fungoides (MF) skin lesions. A double-staining indirect immunofluorescence method was used. Cells suggestive of keratinocytes reacted with the anti-Ia antibodies in some cases of MF lesions, while no such pattern was seen with the thymocyte-antigen antibodies (OK T6). In other cases o ...
Pages: 241-243
Abstract  PDF
Thiol levels in normal and psoriatic corneocytes
PD Mier, H. van Rennes
No abstract available.
Pages: 243-246
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Phototoxic reactions from some common drugs provoked by a high-intensity UVA lamp
K. Rosén, G. Swanbeck
No abstract available.
Pages: 246-248
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In vitro studies on blastogenic lymphokine activity in nickel allergy
TM MacLeod, F Hutchinson, EJ. Raffle
No abstract available.
Pages: 249-250
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Histamine receptor bearing suppressor cells in nickel sensitivity
S. Silvennoinen-Kassinen
No abstract available.
Pages: 251-253
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Clinical evaluation and pathomechanism of urticaria-like skin eruption in systemic lupus erythematosus
A. Horváth, M. Krámer, E. Ablonczy
Clinical observations of 10 SLE patients having urticaria-like skin symptoms showed that the clinical process of urticaria found in patients suffering from SLE differs from the classic one. On the basis of histological and immunohistological studies in 5 cases, a characteristic histological manifestation of leukocytoclastic vasculitis of small veins in the upper third of the cutis was found. The v ...
Pages: 253-256
Abstract  PDF
Cutaneous periarteritis nodosa occurring during pregnancy
A. Janin-Mercier, AJ Beyvin, M Pablo, B. Jacquetin
No abstract available.
Pages: 256-258
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Palmoplantar pustulosis: a neurocutaneous disease?
K. Hamann
No abstract available.
Pages: 258-260
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Forty years of diarrhoea in a patient with urticaria pigmentosa
JM Mahood, CI Harrington, DN Slater, CL. Corbett
A patient with urticaria pigmentosa who gave a 40-year history of diarrhoea was found to have systemic mastocytosis with gut involvement. The radiological appearance of the gut in this disease, although not widely recognized, are specific and should be looked for carefully in patients with urticaria pigmentosa who complain of gastro-intestinal symptoms. Gastro-intestinal symptoms, due mainly to al ...
Pages: 264-265
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Suppression of erythema nodosum by indomethacin
Z Ubogy, RH.Perselli
Erythema nodosum (EN) can be a debilitating illness. Many treatment modalities have been suggested but none is universally effective. We describe three patients with severe EN secondary to streptococcal pharyngitis who were unresponsive to large doses of aspirin. Following the administration of indomethacin in doses of 100 to 150 mg per day, all three showed a dramatic response, with prompt resolu ...
Pages: 265-266
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Comparison of two application schedules for clobetasol 17 propionate
LC vd Harst, H de Jonge, FPot, MK. Polano
No abstract available.
Pages: 270-273
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Ketoconazole in Trichophyton rubrum
G. Laurberg
10 patients with T. rubrum infection were treated with Ketoconazole 200-400 mg a day for 8 weeks. All patients had a skin infection and 2 in addition infection of the toe nails. Previous treatment with Griseofulvin and at least two different antifungal topicals had been ineffective. The infection was evaluated by clinical findings and mycological examination. The skin lesions disappeared in 6 pati ...
Pages: 273-274
Abstract  PDF
Venereal disease in patients with scabies: a five-year survey
JM Munkvad, AO Nielsen, L. Secher
No abstract available.
Pages: 274-275
Abstract  PDF