Content - Volume 68, Issue

All articles

Pharmacokinetics of small doses of methotrexate in patients with psoriasis
Kamel RS, al-Hakiem MH, Rademaker M, Meyrick Thomas RH, Munro DD
The pharmacokinetics of methotrexate was studied in 23 patients with chronic plaque psoriasis. Ten patients received a single oral does and 13 patients a single intramuscular injection of 25 mg methotrexate. Serum methotrexate was measured for 24 hours following administration of the drug using a magnetizable solid-phase radio-immunoassay. The disappearance of methotrexate from the serum fitted a ...
Pages: 267-270
Abstract  PDF
Does topical minoxidil increase skin blood flow? A laser Doppler flowmetry study
de Boer EM, Bezemer PD, Bruynzeel DP, Nieboer C.
Cutaneous blood flow was measured by Laser Doppler Flowmetry after topical application of minoxidil lotion, in 9 healthy males with androgenetic alopecia, and other volunteers. No reaction in the cutaneous blood flow was seen after application of 2%, 5%, or placebo minoxidil lotion.
Pages: 271-274
Abstract  PDF