Content

Content - Volume 79, Issue 2

Editor's choice in this issue

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The multifaceted face of Acta Dermato-Venereologica
Anders Vahlquist
This article does not have an abstract.
Page: 97
Abstract  PDF
Decreased Chymase Activity is Associated with Increased Levels of Protease Inhibitors in Mast Cells of Psoriatic Lesions
Ilkka T. Harvima, Leena Haapanen, Leena Ackermann, Anita Naukkarinen, Rauno J Harvima, Maija Horsmanheimo
Mast cells contain large amounts of the powerful serine proteinases, tryptase and chymase, of which only chymase can be inactivated by serum protease inhibitors. In this study, 20 patients with psoriasis and a control group of 13 with atopic dermatitis were biopsied for lesional and non-lesional skin specimens. The presence of chymase inhibitor α1-proteinase inhibitor (α1-PI), α1-antichymotryp ...
Pages: 98-104
Abstract  PDF
Expression and Function of ß2 Integrin CD11B/CD18 on Leukocytes from Patients with Psoriasis
F. Sjögren, O. Ljunghusen, A. Baas, B.-I. Coble, O. Stendahl
The expression of β2 integrin CD11b on granulocytes and monocytes from patients with psoriasis vulgaris and pustular psoriasis was examined by flow cytometry. The amount of CD11b expressed on both granulocytes and monocytes was greater in 4 patients with pustular psoriasis than in 16 patients with psoriasis vulgaris. Its expression correlated with the development of pustules on the sk ...
Pages: 105-110
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Proliferation is the Main Epidermal Target in the Treatment of Psoriatic Plaques with Once Daily Application of Tacalcitol Ointment
Fransje A. C. M. Castelijns, Marie-Jeanne Gerritsen, Ivonne J. J. van Vlijmen-Willems, Piet J. van Erp, Peter C. M. van de Kerkhof
We studied the effect of tacalcitol (1α,24 dihydroxy vitamin D3) ointment on clinical and immunohistochemical efficacy in psoriatic patients during 2 months of treatment. The psoriasis area and severity index decreased significantly after only 1 month and the total body surface index decreased 55% after 2 months. To characterize the epidermal compartment keratin 14, keratin 16, epidermal growth ...
Pages: 111-114
Abstract  PDF
Correlation Between the Greasiness and the Plasticizing Effect of Moisturizers
Gregor B.E. Jemec, Hans Christian Wulf
Moisturizers are used as cosmetics and as adjuvant therapy in dermatology. The strength or relative efficacy of moisturizers is poorly described and thus advising patients is difficult. It has been suggested that lipidization of the skin by moisturizers and the changes in skin mechanics following the application of a moisturizer may be useful measures of outcome. The aim of this study is to descr ...
Pages: 115-117
Abstract  PDF
Effect of EMLA Pre-treatment on Capsaicin-induced Burning and Hyperalgesia
Gil Yosipovitch, Howard I. Maibach, Michael C. Rowbotham
Capsaicin, which has been studied extensively as a treatment for itch and several chronic pain disorders, induces burning during the first week of therapy, causing a substantial percentage of patients to discontinue treatment prematurely. We examined whether pre-treatment with the topical anesthetic EMLA reduces the burning sensation induced by capsaicin and alters capsaicin effects on thermal se ...
Pages: 118-121
Abstract  PDF
Expression of Trichohyalin in Dermatological Disorders: a Comparative Study with Involucrin and Filaggrin by Immunohistochemical Staining
Seung-Chul Lee, Jee-Bum Lee, Jae-Jeong Seo, Young Pio Kim
To investigate the function of trichohyalin during terminal differentiation of the skin, immunohistochemical studies were performed on trichohyalin and its related proteins, filaggrin and involucrin, the components of the cornified cell envelope. In skin disorders unrelated to tumours, weak trichohyalin expression was found in a few granular cells or in the horny layer of psoriasis, ichthyosis, k ...
Pages: 122-126
Abstract  PDF
Does Class Switching Contribute to Remission in Bullous Pemphigoid?
B. Modre, J. Allen, F. Wojnarowska
A correlation between the titre of circulating IgG autoantibodies and disease activity has been difficult to demonstrate in bullous pemphigoid. We postulate that isotype switching from "inflammatory" IgG1 to "blocking" IgG4 subclass antibodies might contribute to disease remission. We studied 16 patients with bullous pemphigoid, 3 patients with cicatricial pemphigoid and 2 patients with epidermol ...
Pages: 127-131
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Squamous Cell Carcinoma-related Antigen (SCCr-Ag), sICAM-1 and ß2-Microglobulin are Useful Markers of Disease Activity in Psoriasis
O. De Pità, A. Frezzolini, A. Cianetti, G. De Sanctis, L. Fontana, V. Bottari
Several published studies suggest the involvement of immune and inflammatory factors in psoriasis. We recently demonstrated that the number of circulating ICAM-1+ lymphocytes and the levels β2-microglobulin are useful parameters in monitoring the activity of the disease. In this study we investigated serum levels of SCCr-Ag in 24 patients with psoriasis in order to determine whether this antigen ...
Pages: 132-135
Abstract  PDF
Unusual Skin Reaction to Silicone Content in Breast Implants
Jan A. Marcusson, Bolli Bjarnason
We present a patient who had a long history of unsuccessful bilateral mammary operations with insertion and extraction of various implants, some of which were filled with silicone gel, others with saline. In addition to complications in the tissue surrounding the prosthesis, she had distant widespread skin lesions which, we believe, were due to leakage from the implant. A cutaneous test with mate ...
Pages: 136-138
Abstract  PDF
Evaluation of Systemic Provocation Tests in Patients with Suspected Allergic and Pseudoallergic Drug Reactions
Ulrich R. Hein, Sibylla Chantraine-Hess, Margitta Worm, Torsten Zuberbier, Beate M. Henz
In order to examine the diagnostic value of systemic provocation tests, we studied 56 inpatients hospitalized for identification of the agent eliciting previous severe allergic or pseudoallergic reactions to non-steroidal anti-inflammatory drugs, local anaesthetics or antibiotics. Skin tests were positive in only 4 patients reacting to antibiotics and propyphenazone and were always negative for l ...
Pages: 139-142
Abstract  PDF
Most "Sporadic" Cases of X-linked Ichthyosis are not De Novo Mutations
S. A. Cuevas-Covarrubias, M. Valdes-Flores, E. Orozco Orozco, J. C. Díaz-Zagoya, S. H. Kofman-Alfaro
X-linked ichthyosis is an inherited disease with dark, regular and adherent scales as clinical characteristics. It is caused by a deficiency of the steroid sulphatase enzyme. Steroid sulphatase assay is a relative easy tool that enables correct diagnosis of X-linked ichthyosis patients and carriers. A large number of X-linked ichthyosis patients correspond to non-familial cases that seem to repre ...
Pages: 143-144
Abstract  PDF
Unilateral Linear Lichen Planus with Mucous Membrane Involvement
Christoph Hartl, Kay H. Steen, Holger Wegner, Heinz-Werner Seifert, Thomas Bieber
Linear lichen planus is a rare distinctive variant of lichen planus (LP) characterized by a pruritic eruption of lichenoid, violaceous papules in a linear distribution that sometimes assume a Blaschko line pattern. We describe a 33-year-old woman who presented with a 4-month history of a slightly pruritic unilateral linear array of papular lesions on the left side of her neck that were clinically ...
Pages: 145-146
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Skin Scrape Cytology in the Diagnosis of Nodular Basal Cell Carcinoma for Treatment by Photodynamic Therapy
Aasmund Berner, Ana Soler, Trond Warloe
Photodynamic therapy is a new mode of cancer treatment with promising results for basal cell carcinoma. The current study aims to investigate the accuracy of skin scrape cytology in the diagnosis of basal cell carcinoma as an integrated part of the treatment procedure. A total of 107 nodular basal cell carcinomas of the skin from 90 patients were examined and cytological and histological diagnose ...
Pages: 147-149
Abstract  PDF
Excision Repair Defect in Rothmund Thomson Syndrome
F. Vasseur, E. Delaporte, M. T. Zabot, M. N. Sturque, D. Barrut, J. B. Savary, L. Thomas, P. Thomas
Rothmund Thomson syndrome is a rare autosomal recessive skin disorder. The main clinical feature is poikiloderma appearing in early childhood associated with skeletal abnormalities. Early occurrence of malignancies is another relevant feature. Here we describe the clinical features of 2 patients with Rothmund Thomson syndrome who were investigated for the in vitro DNA repair capacities of ...
Pages: 150-152
Abstract  PDF
Cutaneous T-cell Lymphoma and Human Immunodeficiency Virus Infection: 2 Cases and a Review of the Literature
M. A. Muñoz-pérez, J. J. Ríos-Martín, A. Rodriguez-Pichardo, F. Camacho
Cutaneous non-Hodgkin's lymphomas are rare in patients with HIV-1 infection and almost all of the cases reported are of T-cell lineage with histopathological features of mycosis fungoides or Sezary syndrome. We studied 2 cases of mycosis fungoides in HIV-1-positive patients who were intravenous drug abusers and were in stage II and IV C2 (CDC'86), respectively. The first patient (stage II) had mu ...
Pages: 153-155
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The Role of Low Resistance Blood Flow Pathways in the Pathogenesis and Healing of Venous Leg Ulcers
Ken Malanin, Pertti J Kolari, Väinö K Havu
In an attempt to clarify the pathophysiology of haemodynamics in legs with venous ulcer we investigated the effect of a single intermittent pneumatic compression treatment on the peripheral resistance of leg arteries and the cutaneous laser Doppler flux in the leg. Eight patients with venous leg ulcers and 10 subjects with healthy legs were investigated. Doppler waveforms of the leg arteries and ...
Pages: 156-160
Abstract  PDF
Annular Pustular Psoriasis Localized to the Dorsa of the Feet
Young Min Park, Hoon Kang, Baik Kee Cho
This article does not have an abstract.
Pages: 161-162
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Cellular Neurothekeoma
R. Strumìa, A. R. Lombardi, L. Cavazzini
This article does not have an abstract.
Pages: 162-163
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Inflammatory Linear Verrucous Epidermal Naevus Arising on a Burn Scar
In Wook Lee, Sung Ku Ahn, Eung Ho Choi
This article does not have an abstract.
Pages: 164-165
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Anti-centromere Antibodies in 2 Patients with Discoid Lupus Erythematosus and No Signs of Systemic Sclerosis
M. G. Aragone, S. Balestrero, A. Parodi, A. Rebora
This article does not have an abstract.
Pages: 165-166
Abstract  PDF
Erythema Multiforme-like Eruptions Induced by Cytomegalovirus Infection in an Immunocompetent Adult
Tetsuya Koga, Yumiko Kubota, Juichiro Nakayama
This article does not have an abstract.
Page: 166
Abstract  PDF
Dermatomyositis Associated with Testicular Tumour with Elevation of Serum Lactate Dehydrogenase (LDH) Isoenzyme-1
Toshiyuki Ishizawa, Yoshihiko Mitsuhashi, Shigeo Kondo
This article does not have an abstract.
Page: 167
Abstract  PDF
Localized Chronic Urticaria at the Site of Healed Herpes Zoster
Hyun-Jeong Lee, Won-Keun Ahn, Koo-Seong Chae, Seog-Jun Ha, Jin-Wou Kim
This article does not have an abstract.
Page: 168
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Acne Conglobata after Pregnancy
Han P. A. van Pelt, Lennart Juhlin
This article does not have an abstract.
Page: 169
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Acute Balanoposthitis Caused by Infestation with Cordylobia anthropophaga
C. S. Petersen, C. Zachariae
This article does not have an abstract.
Page: 170
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Skin Necrosis Caused by Flunitrazepam Abuse
S. Menni, D. Boccardi, A. Coggi
This article does not have an abstract.
Page: 171
Abstract  PDF
Immunohistochemical Detection of erbB-4 Expression in Extramammary Paget's Disease
Sumihisa Imakado, Hisae Satomi, Fujio Otsuka
This article does not have an abstract.
Page: 172
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Chemotherapy-induced Acral Erythema
E. Vargas-Díez, P. Abajo, J. Fraga, J. Fernández-Herrera, A. García-Díez
This article does not have an abstract.
Pages: 173-174
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Announcements
This article does not have an abstract.
Page: 176
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Books Received
Lennart Juhlin
This article does not have an abstract.
Page: 176
Abstract  PDF